| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiyi Hu, Linglian Kong, Chuanpi Xiao, Qidong Zhu, Zhigang Son. The AMPK-mTOR signaling pathway is involved in regulation of food intake in the hypothalamus of stressed chickens. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 258. 2021-09-02. PMID:33991669. |
the ampk-mtor signaling pathway is involved in regulation of food intake in the hypothalamus of stressed chickens. |
2021-09-02 |
2023-08-13 |
Not clear |
| b' V Hainer, I Aldhoon Hainerov\\xc3\\xa1, M Kune\\xc5\\xa1ov\\xc3\\xa1, R Taxov\\xc3\\xa1 Braunerov\\xc3\\xa1, H Zamrazilov\\xc3\\xa1, B Bendlov\\xc3\\xa. Melanocortin pathways: suppressed and stimulated melanocortin-4 receptor (MC4R). Physiological research. vol 69. issue Suppl 2. 2021-08-31. PMID:33094623.' |
enhanced melanocortin signaling in the hypothalamus results in both decreased food intake and increased energy expenditure. |
2021-08-31 |
2023-08-13 |
Not clear |
| Yang-Wen Hsieh, Yi-Wen Tsai, Hsin-Hung Lai, Chi-Yu Lai, Chiu-Ya Lin, Guor Mour He. Depletion of Alpha-Melanocyte-Stimulating Hormone Induces Insatiable Appetite and Gains in Energy Reserves and Body Weight in Zebrafish. Biomedicines. vol 9. issue 8. 2021-08-30. PMID:34440144. |
the functions of anorexigenic neurons secreting proopiomelanocortin (pomc)/alpha-melanocyte-stimulating hormone (α-msh) of the melanocortin system in the hypothalamus in vertebrates are energy homeostasis, food intake, and body weight regulation. |
2021-08-30 |
2023-08-13 |
zebrafish |
| Ehsan Pashay Ahi, Emmanouil Tsakoumis, Mathilde Brunel, Monika Schmit. Transcriptional study reveals a potential leptin-dependent gene regulatory network in zebrafish brain. Fish physiology and biochemistry. vol 47. issue 4. 2021-08-25. PMID:34236575. |
in mammals and many teleost fish species, leptin has an anorexigenic role and inhibits food intake by influencing the appetite centres in the hypothalamus. |
2021-08-25 |
2023-08-13 |
zebrafish |
| Cecilie Hundahl, Petra Kotzbeck, Hayley B Burm, Søren H Christiansen, Lola Torz, Aske W Helge, Martin P Madsen, Cecilia Ratner, Annette K Serup, Jonatan J Thompson, Thomas O Eichmann, Tune H Pers, David P D Woldbye, Daniele Piomelli, Bente Kiens, Rudolf Zechner, Louise J Skov, Birgitte Hols. Hypothalamic hormone-sensitive lipase regulates appetite and energy homeostasis. Molecular metabolism. vol 47. 2021-08-19. PMID:33549847. |
the goal of this study was to investigate the importance of central hormone-sensitive lipase (hsl) expression in the regulation of food intake and body weight in mice to clarify whether intracellular lipolysis in the mammalian hypothalamus plays a role in regulating appetite. |
2021-08-19 |
2023-08-13 |
mouse |
| Rafael C Gaspar, Susana C B R Nakandakari, Vitor R Muñoz, Renan F L Vieira, Adelino S R da Silva, Dennys E Cintra, Leandro P de Moura, Eduardo R Ropelle, José Rodrigo Paul. Acute physical exercise increases PI3K-p110α protein content in the hypothalamus of obese mice. Journal of anatomy. vol 238. issue 3. 2021-08-13. PMID:33094520. |
thus, in the current study, we evaluated the role of acute exercise in the leptin and insulin pathways in the hypothalamus, as well as in food intake control in obese mice. |
2021-08-13 |
2023-08-13 |
mouse |
| Rafael C Gaspar, Susana C B R Nakandakari, Vitor R Muñoz, Renan F L Vieira, Adelino S R da Silva, Dennys E Cintra, Leandro P de Moura, Eduardo R Ropelle, José Rodrigo Paul. Acute physical exercise increases PI3K-p110α protein content in the hypothalamus of obese mice. Journal of anatomy. vol 238. issue 3. 2021-08-13. PMID:33094520. |
for the first time, our results indicate physical exercise can increase pi3k-p110α protein content in the hypothalamus of obese mice and regulate food intake. |
2021-08-13 |
2023-08-13 |
mouse |
| Taylor Landry, Daniel Shookster, Alec Chaves, Katrina Free, Tony Nguyen, Hu Huan. Energy Status Differentially Modifies Feeding Behavior and POMC Frontiers in endocrinology. vol 12. 2021-08-10. PMID:34220725. |
consequently, the current study utilized a translational, well-controlled, within-subject, treadmill exercise protocol to investigate the differential effects of energy status and exercise intensity on post-exercise feeding behavior and appetite-controlling neurons in the hypothalamus. |
2021-08-10 |
2023-08-13 |
mouse |
| Silvie R Ruigrok, Nina Stöberl, Kit-Yi Yam, Chiara de Lucia, Paul J Lucassen, Sandrine Thuret, Aniko Koros. Modulation of the Hypothalamic Nutrient Sensing Pathways by Sex and Early-Life Stress. Frontiers in neuroscience. vol 15. 2021-08-10. PMID:34366778. |
the hypothalamus regulates food intake and energy expenditure by sensing the organism's energy state via metabolic hormones (leptin, insulin, ghrelin) and nutrients (glucose, fatty acids). |
2021-08-10 |
2023-08-13 |
mouse |
| Jingjing Sun, Yuqing She, Penghua Fang, Xuewen Gu, Zhenwen Zhan. Time-restricted feeding prevents metabolic diseases through the regulation of galanin/GALR1 expression in the hypothalamus of mice. Eating and weight disorders : EWD. 2021-08-09. PMID:34370270. |
time-restricted feeding prevents metabolic diseases through the regulation of galanin/galr1 expression in the hypothalamus of mice. |
2021-08-09 |
2023-08-13 |
mouse |
| Jianfeng Liu, Stoyan Dimitrov, Anuck Sawangjit, Jan Born, Ingrid Ehrlich, Manfred Hallschmi. Short-term high-fat feeding induces a reversible net decrease in synaptic AMPA receptors in the hypothalamus. The Journal of nutritional biochemistry. vol 87. 2021-08-04. PMID:33022406. |
short-term high-fat feeding induces a reversible net decrease in synaptic ampa receptors in the hypothalamus. |
2021-08-04 |
2023-08-13 |
rat |
| Li Wang, Chao-Chao Yu, Jia Li, Qing Tian, Yan-Jun D. Mechanism of Action of Acupuncture in Obesity: A Perspective From the Hypothalamus. Frontiers in endocrinology. vol 12. 2021-07-30. PMID:33868169. |
as the key pivot of appetite signals, the hypothalamus receives afferent and efferent signals from the brainstem and peripheral tissue, leading to the formation of a complex appetite regulation circuit, thereby effectively regulating food intake and energy homeostasis. |
2021-07-30 |
2023-08-13 |
Not clear |
| Cristina Velasco, Marta Conde-Sieira, Sara Comesaña, Mauro Chivite, Jesús M Míguez, José L Soenga. Role of the G protein-coupled receptors GPR84 and GPR119 in the central regulation of food intake in rainbow trout. The Journal of experimental biology. vol 224. issue 13. 2021-07-30. PMID:34114000. |
in the second experiment, we assessed the impact of the same treatments on mrna abundance in the hypothalamus and hindbrain of neuropeptides involved in the metabolic control of food intake (npy, agrp1, pomca1 and cartpt) as well as in changes in parameters related to signalling pathways and transcription factors involved in the integrative response leading to neuropeptide production. |
2021-07-30 |
2023-08-13 |
Not clear |
| Darren Mehay, Yuval Silberman, Amy C Arnol. The Arcuate Nucleus of the Hypothalamus and Metabolic Regulation: An Emerging Role for Renin-Angiotensin Pathways. International journal of molecular sciences. vol 22. issue 13. 2021-07-29. PMID:34208939. |
the control of energy balance involves the actions of circulating hormones on a widely distributed network of brain regions involved in the regulation of food intake and energy expenditure, including the arcuate nucleus of the hypothalamus. |
2021-07-29 |
2023-08-13 |
Not clear |
| Mahtab Keshvari, Mahdieh Nejadtaghi, Farnaz Hosseini-Beheshti, Ali Rastqar, Niraj Pate. Exploring the role of circadian clock gene and association with cancer pathophysiology. Chronobiology international. vol 37. issue 2. 2021-07-28. PMID:31791146. |
in mammals, the circadian clock system is hierarchically organized such that the master clock in the suprachiasmatic nuclei of the hypothalamus integrates environmental information and synchronizes the phase of oscillators in peripheral tissues.the circadian system is responsible for regulating a variety of physiological and behavioral processes, including feeding behavior and energy metabolism. |
2021-07-28 |
2023-08-13 |
Not clear |
| Virginie Tolle, Nicolas Ramoz, Jacques Epelbau. Is there a hypothalamic basis for anorexia nervosa? Handbook of clinical neurology. vol 181. 2021-07-28. PMID:34238474. |
the hypothalamus has long been known to control food intake and energy metabolism through a complex network of primary and secondary neurons and glial cells. |
2021-07-28 |
2023-08-13 |
Not clear |
| María Paz Hernández-Cáceres, Karina Cereceda, Sergio Hernández, Ying Li, Carla Narro, Patricia Rivera, Patricio Silva, Yenniffer Ávalos, Claudia Jara, Paulina Burgos, Lilian Toledo-Valenzuela, Pablo Lagos, Flavia Cifuentes Araneda, Claudio Perez-Leighton, Cristina Bertocchi, Deborah J Clegg, Alfredo Criollo, Cheril Tapia-Rojas, Patricia V Burgos, Eugenia Morsell. Palmitic acid reduces the autophagic flux in hypothalamic neurons by impairing autophagosome-lysosome fusion and endolysosomal dynamics. Molecular & cellular oncology. vol 7. issue 5. 2021-07-26. PMID:32944643. |
long-term feeding with hfd increases the concentration of the saturated fatty acid palmitic acid (pa) in the hypothalamus. |
2021-07-26 |
2023-08-13 |
Not clear |
| L D Prezotto, J F Thorson, V Prevot, D A Redmer, A T Grazul-Bilsk. Nutritionally induced tanycytic plasticity in the hypothalamus of adult ewes. Domestic animal endocrinology. vol 72. 2021-07-23. PMID:32388344. |
the blood-brain barrier regulates the transport of molecules that convey global energetic status to the feeding circuitry within the hypothalamus. |
2021-07-23 |
2023-08-13 |
Not clear |
| Liu Ye, Gongwei Jia, Yuejie Li, Ying Wang, Hong Chen, Lehua Yu, Dandong W. C1q/TNF-related protein 4 restores leptin sensitivity by downregulating NF-κB signaling and microglial activation. Journal of neuroinflammation. vol 18. issue 1. 2021-07-22. PMID:34275474. |
c1qtnf-related protein 4 (ctrp4) acts in the hypothalamus to modulate food intake in diet-induced obese mice and has been shown to exert an anti-inflammatory effect on macrophages. |
2021-07-22 |
2023-08-13 |
mouse |
| Yirui He, Cheng Zhang, Yong Luo, Jinhua Chen, Mengliu Yang, Ling Li, Harvest F Gu, Gangyi Yang, Xianxiang Zhan. Hypothalamic BMP9 suppresses glucose production by central PI3K/Akt/mTOR pathway. The Journal of endocrinology. vol 248. issue 2. 2021-07-20. PMID:33337347. |
overexpression of bmp9 in the mediobasal hypothalamus reduced food intake, body weight, and blood glucose level, and elevated the energy expenditure in high-fat diet (hfd)-fed mice. |
2021-07-20 |
2023-08-13 |
mouse |