| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Matthew K H Wong, Yuan Chen, Mulan He, Chengyuan Lin, Zhaoxiang Bian, Anderson O L Won. Mouse Spexin: (II) Functional Role as a Satiety Factor inhibiting Food Intake by Regulatory Actions Within the Hypothalamus. Frontiers in endocrinology. vol 12. 2021-11-18. PMID:34276562. |
furthermore, ip injection of spx was effective in reducing food intake with parallel attenuation in transcript expression of npy, agrp, npy type 5 receptor (npy5r), and ghrelin receptor (ghsr) in the hypothalamus, and these inhibitory effects could be blocked by galr3 but not galr2 antagonism. |
2021-11-18 |
2023-08-13 |
mouse |
| Matthew K H Wong, Yuan Chen, Mulan He, Chengyuan Lin, Zhaoxiang Bian, Anderson O L Won. Mouse Spexin: (II) Functional Role as a Satiety Factor inhibiting Food Intake by Regulatory Actions Within the Hypothalamus. Frontiers in endocrinology. vol 12. 2021-11-18. PMID:34276562. |
through galr3 activation, this spx signal can act within the hypothalamus to trigger feedback inhibition on feeding by differential modulation of feeding regulators (npy and agrp) and their receptors (npy5r, ghsr, lepr, and mc4r) involved in the feeding circuitry within the cns. |
2021-11-18 |
2023-08-13 |
mouse |
| Izabelle Dias Benfato, Ana Carolina Silvares Quintanilha, Jessica Salles Henrique, Melyssa Alves Souza, Barbara Dos Anjos Rosário, Jose Ivo Araújo Beserra Filho, Robson Luiz Oliveira Santos, Alessandra Mussi Ribeiro, Luciana Le Sueur Maluf, Camila Aparecida Machado de Oliveir. Effects of long-term social isolation on central, behavioural and metabolic parameters in middle-aged mice. Behavioural brain research. vol 417. 2021-11-15. PMID:34656691. |
food intake was also affected, but the direction depended on how it was measured in the social group (individually or in the group) with no alteration in Δfosb at the hypothalamus. |
2021-11-15 |
2023-08-13 |
mouse |
| Lorena López-Ferreras, Francesco Longo, Jennifer E Richard, Kim Eerola, Olesya T Shevchouk, Madeleine Tuzinovic, Karolina P Skibick. Key role for hypothalamic interleukin-6 in food-motivated behavior and body weight regulation. Psychoneuroendocrinology. vol 131. 2021-11-12. PMID:34090139. |
thus, collectively these data support the idea that brain-produced il-6 engages the hypothalamus to control feeding behavior. |
2021-11-12 |
2023-08-13 |
rat |
| Lucia Recinella, Annalisa Chiavaroli, Giustino Orlando, Claudio Ferrante, Iacopo Gesmundo, Riccarda Granata, Renzhi Cai, Wei Sha, Andrew V Schally, Luigi Brunetti, Sheila Leon. Growth hormone-releasing hormone antagonistic analog MIA-690 stimulates food intake in mice. Peptides. vol 142. 2021-11-09. PMID:34051291. |
the stimulation of feeding could be mediated, albeit partially, by elevation of agrp gene expression and ne levels and decreased 5-ht levels in the hypothalamus, along with reduced leptin gene expression, in the visceral adipose tissue. |
2021-11-09 |
2023-08-13 |
mouse |
| Kelly Meneyrol, Ánxela Estévez-Salguero, Ismael González-García, Jeanne Guitton, Mohammed Taouis, Yacir Benomar, Christophe Magnan, Miguel López, Hervé Le Stunf. Ovarian insufficiency impairs glucose-stimulated insulin secretion through activation of hypothalamic de novo ceramide synthesis. Metabolism: clinical and experimental. vol 123. 2021-11-09. PMID:34371064. |
oestrogens regulate body weight through their action on hypothalamus to modulate food intake and energy expenditure. |
2021-11-09 |
2023-08-13 |
rat |
| Kazuhiro Nakamura, Yoshiko Nakamura, Naoya Kataok. A hypothalamomedullary network for physiological responses to environmental stresses. Nature reviews. Neuroscience. 2021-11-03. PMID:34728833. |
under starvation stress, medullary reticular neurons activated by hunger signalling from the hypothalamus suppress thermogenic drive from the rmr for energy saving and prime mastication to promote food intake. |
2021-11-03 |
2023-08-13 |
Not clear |
| Nanette Y Schneider, Sylvie Chaudy, Alberto L Epstein, Cécile Viollet, Alexandre Benani, Luc Pénicaud, Xavier Grosmaître, Frédérique Datiche, Jean Gascue. Centrifugal projections to the main olfactory bulb revealed by transsynaptic retrograde tracing in mice. The Journal of comparative neurology. vol 528. issue 11. 2021-11-02. PMID:31872441. |
our tracing experiments showed that the arcuate nucleus of the hypothalamus, as a major site for regulation of food intake, sends only very indirect projections onto the mob. |
2021-11-02 |
2023-08-13 |
mouse |
| Jo B Henningsen, Camilla Scheel. Brown Adipose Tissue: A Metabolic Regulator in a Hypothalamic Cross Talk? Annual review of physiology. vol 83. 2021-11-01. PMID:33158377. |
interestingly, bat is regulated by multiple interactions with the hypothalamus from regions overlapping with centers for feeding behavior and metabolic control. |
2021-11-01 |
2023-08-13 |
human |
| Adrián Díaz-Rúa, Mauro Chivite, Sara Comesaña, Cristina Velasco, José L Soengas, Marta Conde-Sieir. Central administration of endocannabinoids exerts bimodal effects in food intake of rainbow trout. Hormones and behavior. vol 134. 2021-11-01. PMID:34242873. |
the results obtained indicate that whereas high doses of endocannabinoids did not elicit changes in food intake levels, low doses of the endocannabinoids produce an orexigenic effect that could be due to a possible inhibition of gabaergic neurotransmission and the modulation of neural plasticity in brain areas related to appetite control, such as hypothalamus and telencephalon. |
2021-11-01 |
2023-08-13 |
Not clear |
| Felicitas Lopez-Vicchi, Catalina De Winne, Belen Brie, Eleonora Sorianello, Sharon R Ladyman, Damasia Becu-Villalobo. Metabolic functions of prolactin: Physiological and pathological aspects. Journal of neuroendocrinology. vol 32. issue 11. 2021-10-29. PMID:33463813. |
prolactin receptors are found in many tissues involved in metabolism and food intake, such as the pancreas, liver, hypothalamus, small intestine and adipose tissue. |
2021-10-29 |
2023-08-13 |
Not clear |
| Tomasz Antoni Guzel, Katarzyna Mech, Marek Wroński, Katarzyna Gerkowicz, Agata Bednarczyk, Weronika Adamczyk, Monika Radecka, Maciej Słodkowsk. Brain-derived neurotrophic factor in gastroenterology oncology - short review of current literature. Annals of agricultural and environmental medicine : AAEM. vol 28. issue 3. 2021-10-26. PMID:34558255. |
in the hypothalamus it is described as playing a role in energy metabolism and feeding behaviour. |
2021-10-26 |
2023-08-13 |
Not clear |
| Tetsuya Shiuchi, Airi Otsuka, Noriyuki Shimizu, Sachiko Chikahisa, Hiroyoshi Sé. Feeding Rhythm-Induced Hypothalamic Agouti-Related Protein Elevation via Glucocorticoids Leads to Insulin Resistance in Skeletal Muscle. International journal of molecular sciences. vol 22. issue 19. 2021-10-25. PMID:34639172. |
hepatic vagotomy enhanced agrp expression in the hypothalamus even during ad-lib feeding in wild-type mice but not in agrp-gr-ko mice. |
2021-10-25 |
2023-08-13 |
mouse |
| Xiao-Yan Liu, Jian-Hua Shi, Wen-Hua DU, Yan-Ping Fan, Xiao-Lei Hu, Chen-Chen Zhang, Huan-Bai Xu, Yan-Jun Miao, Hai-Yan Zhou, Ping Xiang, Feng-Ling Che. Glucocorticoids decrease body weight and food intake and inhibit appetite regulatory peptide expression in the hypothalamus of rats. Experimental and therapeutic medicine. vol 2. issue 5. 2021-10-21. PMID:22977608. |
glucocorticoids decrease body weight and food intake and inhibit appetite regulatory peptide expression in the hypothalamus of rats. |
2021-10-21 |
2023-08-12 |
rat |
| Qingchun Tong, Yong X. Central Leptin Regulation of Obesity and Fertility. Current obesity reports. vol 1. issue 4. 2021-10-21. PMID:23243628. |
it is now well established that the brain, especially the hypothalamus, maintains body weight homeostasis by effectively adjusting food intake and energy expenditure in response to changes in levels of various nutritional status indicators, including leptin. |
2021-10-21 |
2023-08-12 |
Not clear |
| M Dworak, T Kim, R W McCarley, R Bashee. Sleep, brain energy levels, and food intake: Relationship between hypothalamic ATP concentrations, food intake, and body weight during sleep-wake and sleep deprivation in rats. Somnologie : Schlafforschung und Schlafmedizin = Somnology : sleep research and sleep medicine. vol 15. issue 2. 2021-10-21. PMID:23585726. |
the feeling of hunger and feeding, a wake-state-dependent behavior, is regulated by specific centers within the hypothalamus. |
2021-10-21 |
2023-08-12 |
rat |
| Dongsheng Cai, Sudarshana Purkayasth. A New Horizon: Oxytocin as a Novel Therapeutic Option for Obesity and Diabetes. Drug discovery today. Disease mechanisms. vol 10. issue 1-2. 2021-10-21. PMID:24159336. |
in light of metabolic control, oxt has been shown to induce feeding restriction and body weight lowering through acting on brain regulatory regions, in particular the hypothalamus. |
2021-10-21 |
2023-08-12 |
human |
| Asli Zengin Turkmen, Asiye Nurten, Mine Erguven, Emine Bilg. Effects of scopolamine treatment and consequent convulsion development in c‑fos expression in fed, fasted, and refed mice. Acta neurobiologiae experimentalis. vol 81. issue 3. 2021-10-21. PMID:34672296. |
these results demonstrate that re‑feeding and scopolamine treatment induces neuronal activity in the hypothalamus, while scopolamine induced convulsions after food intake suppressed the c‑fos activity. |
2021-10-21 |
2023-08-13 |
mouse |
| Theodore P Braun, Daniel L Mark. Pathophysiology and treatment of inflammatory anorexia in chronic disease. Journal of cachexia, sarcopenia and muscle. vol 1. issue 2. 2021-10-20. PMID:21475703. |
one of the targets of inflammatory mediators is the central nervous system, and in particular feeding centers in the hypothalamus located in the ventral diencephalon. |
2021-10-20 |
2023-08-12 |
Not clear |
| Patrick J Antonellis, Staci E Engle, Kathryn M Brewer, Nicolas F Berbar. The Hedgehog Signaling Pathway is Expressed in the Adult Mouse Hypothalamus and Modulated by Fasting. eNeuro. vol 8. issue 5. 2021-10-20. PMID:34535504. |
here, we provide a detailed analysis of the expression of core components of the hedgehog signaling pathway in the adult mouse hypothalamus with an emphasis on feeding centers. |
2021-10-20 |
2023-08-13 |
mouse |