| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Danny Titolo, Fang Cai, Denise D Belsha. Coordinate regulation of neuropeptide Y and agouti-related peptide gene expression by estrogen depends on the ratio of estrogen receptor (ER) alpha to ERbeta in clonal hypothalamic neurons. Molecular endocrinology (Baltimore, Md.). vol 20. issue 9. 2006-09-28. PMID:16675543. |
neuropeptide y (npy) and agouti-related peptide (agrp) stimulate feeding, whereas npy also facilitates the estrogen-mediated preovulatory gnrh surge. |
2006-09-28 |
2023-08-12 |
Not clear |
| John-Paul Baird, Nora E Gray, Shannon G Fische. Effects of neuropeptide Y on feeding microstructure: dissociation of appetitive and consummatory actions. Behavioral neuroscience. vol 120. issue 4. 2006-09-28. PMID:16893299. |
therefore, npy also increased appetitive feeding behaviors, but its consummatory effects were limited to caloric solutions. |
2006-09-28 |
2023-08-12 |
Not clear |
| E Szentirmai, J M Kruege. Central administration of neuropeptide Y induces wakefulness in rats. American journal of physiology. Regulatory, integrative and comparative physiology. vol 291. issue 2. 2006-09-27. PMID:16914434. |
neuropeptide y (npy) is a well-characterized neuromodulator in the central nervous system, primarily implicated in the regulation of feeding. |
2006-09-27 |
2023-08-12 |
rat |
| E Szentirmai, J M Kruege. Central administration of neuropeptide Y induces wakefulness in rats. American journal of physiology. Regulatory, integrative and comparative physiology. vol 291. issue 2. 2006-09-27. PMID:16914434. |
npy, orexins, and ghrelin form a hypothalamic food intake regulatory circuit. |
2006-09-27 |
2023-08-12 |
rat |
| E Szentirmai, J M Kruege. Central administration of neuropeptide Y induces wakefulness in rats. American journal of physiology. Regulatory, integrative and comparative physiology. vol 291. issue 2. 2006-09-27. PMID:16914434. |
npy stimulated food intake in the first hour after both routes of administration. |
2006-09-27 |
2023-08-12 |
rat |
| E Szentirmai, J M Kruege. Central administration of neuropeptide Y induces wakefulness in rats. American journal of physiology. Regulatory, integrative and comparative physiology. vol 291. issue 2. 2006-09-27. PMID:16914434. |
data are consistent with the hypothesis that npy has a role in the integration of feeding, metabolism, and sleep regulation. |
2006-09-27 |
2023-08-12 |
rat |
| Lourdes Mounien, Patrice Bizet, Isabelle Boutelet, Guillaume Gourcerol, Magali Basille, Bruno Gonzalez, Hubert Vaudry, Sylvie Jego. Expression of PACAP receptor mRNAs by neuropeptide Y neurons in the rat arcuate nucleus. Annals of the New York Academy of Sciences. vol 1070. 2006-09-25. PMID:16888209. |
neuropeptide y (npy) and pituitary adenylate cyclase-activating polypeptide (pacap) exert opposite actions in energy homeostasis: npy is a potent orexigenic peptide whereas pacap reduces food intake. |
2006-09-25 |
2023-08-12 |
rat |
| Lourdes Mounien, Patrice Bizet, Isabelle Boutelet, Guillaume Gourcerol, Magali Basille, Bruno Gonzalez, Hubert Vaudry, Sylvie Jego. Expression of PACAP receptor mRNAs by neuropeptide Y neurons in the rat arcuate nucleus. Annals of the New York Academy of Sciences. vol 1070. 2006-09-25. PMID:16888209. |
this observation indicates that pacap may regulate the activity of npy neurons, suggesting that the inhibitory effect of pacap on food intake may be mediated, at least in part, through modulation of npy neurotransmission. |
2006-09-25 |
2023-08-12 |
rat |
| Paula J Brunton, Juliana Bales, John A Russel. Neuroendocrine stress but not feeding responses to centrally administered neuropeptide Y are suppressed in pregnant rats. Endocrinology. vol 147. issue 8. 2006-08-31. PMID:16675522. |
metabolic peptides such as orexin and neuropeptide y (npy) exert profound effects on feeding but also act centrally to stimulate the hypothalamo-pituitary-adrenal (hpa) axis. |
2006-08-31 |
2023-08-12 |
rat |
| Paula J Brunton, Juliana Bales, John A Russel. Neuroendocrine stress but not feeding responses to centrally administered neuropeptide Y are suppressed in pregnant rats. Endocrinology. vol 147. issue 8. 2006-08-31. PMID:16675522. |
npy increased food intake and drinking similarly in virgin and pregnant rats. |
2006-08-31 |
2023-08-12 |
rat |
| Tomas A Larsson, Frida Olsson, Görel Sundström, Sydney Brenner, Byrappa Venkatesh, Dan Larhamma. Pufferfish and zebrafish have five distinct NPY receptor subtypes, but have lost appetite receptors Y1 and Y5. Annals of the New York Academy of Sciences. vol 1040. 2006-08-29. PMID:15891066. |
the two neuropeptide y (npy) receptors y1 and y5 stimulate feeding in mammals, but are missing in the euteleosts, zebrafish and pufferfish (takifugu rubripes). |
2006-08-29 |
2023-08-12 |
zebrafish |
| Tomas A Larsson, Frida Olsson, Görel Sundström, Sydney Brenner, Byrappa Venkatesh, Dan Larhamma. Pufferfish and zebrafish have five distinct NPY receptor subtypes, but have lost appetite receptors Y1 and Y5. Annals of the New York Academy of Sciences. vol 1040. 2006-08-29. PMID:15891066. |
rt-pcr studies in pufferfish show that all five are expressed in the brain and may mediate npy effects on feeding. |
2006-08-29 |
2023-08-12 |
zebrafish |
| Sujean Choi, Valarie Blake, Sara Cole, John D Fernstro. Effects of chronic fenfluramine administration on hypothalamic neuropeptide mRNA expression. Brain research. vol 1087. issue 1. 2006-08-25. PMID:16626640. |
injections for 15 days and measured mrna expression of corticotropin releasing factor (crf), neuropeptide y (npy) and proopiomelanocortin (pomc) in hypothalamic neurons on days 1, 2 and 15. dl-fen decreased food intake on days 1-2 but not on day 15. |
2006-08-25 |
2023-08-12 |
rat |
| Sujean Choi, Valarie Blake, Sara Cole, John D Fernstro. Effects of chronic fenfluramine administration on hypothalamic neuropeptide mRNA expression. Brain research. vol 1087. issue 1. 2006-08-25. PMID:16626640. |
thus, only the npy mrna response to dl-fen correlated with changes in food intake over time in a manner consistent with the known effects of npy on food intake. |
2006-08-25 |
2023-08-12 |
rat |
| E Szentirmai, I Hajdu, F Obal, James M Kruege. Ghrelin-induced sleep responses in ad libitum fed and food-restricted rats. Brain research. vol 1088. issue 1. 2006-08-25. PMID:16631138. |
hypothalamic ghrelin-, neuropeptide y (npy)-, and orexin-containing neurons form a feeding regulatory circuit. |
2006-08-25 |
2023-08-12 |
rat |
| Shinya Ishii, Jun Kamega. [Thyroid hormone and various other hormones regulate hypothalamic neuropeptide Y (NPY) expression and feeding behavior]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 127. issue 2. 2006-08-18. PMID:16595976. |
[thyroid hormone and various other hormones regulate hypothalamic neuropeptide y (npy) expression and feeding behavior]. |
2006-08-18 |
2023-08-12 |
Not clear |
| Akio Kanatani, Akane Ishihara, Hisashi Iwaasa, Douglas J MacNeil, Takehiro Fukam. [Development of anorectic NPY antagonists: possible roles of Y1 and Y5 receptors in feeding regulation]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 127. issue 2. 2006-08-18. PMID:16595978. |
[development of anorectic npy antagonists: possible roles of y1 and y5 receptors in feeding regulation]. |
2006-08-18 |
2023-08-12 |
Not clear |
| Michel Félétou, Jean-Pierre Galizzi, Nigel R Leven. NPY receptors as drug targets for the central regulation of body weight. CNS & neurological disorders drug targets. vol 5. issue 3. 2006-08-18. PMID:16787228. |
neuropeptide y (npy) is present in the hypothalamus, where it is believed to play a key role in the control of food intake. |
2006-08-18 |
2023-08-12 |
mouse |
| Michel Félétou, Jean-Pierre Galizzi, Nigel R Leven. NPY receptors as drug targets for the central regulation of body weight. CNS & neurological disorders drug targets. vol 5. issue 3. 2006-08-18. PMID:16787228. |
evidence for this assertion has come from studies demonstrating that acute administration of npy into the hypothalamus or into the brain ventricles leads to increased food intake. |
2006-08-18 |
2023-08-12 |
mouse |
| Michel Félétou, Jean-Pierre Galizzi, Nigel R Leven. NPY receptors as drug targets for the central regulation of body weight. CNS & neurological disorders drug targets. vol 5. issue 3. 2006-08-18. PMID:16787228. |
npy levels in the hypothalamus are temporally correlated with food intake and are markedly elevated in response to energy depletion. |
2006-08-18 |
2023-08-12 |
mouse |