| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daniel Navar, Dana Saulis, Connie Corll, Frank Svec, Johnny R Porte. Dehydroepiandrosterone (DHEA) blocks the increase in food intake caused by neuropeptide Y (NPY) in the Zucker rat. Nutritional neuroscience. vol 9. issue 5-6. 2007-03-06. PMID:17263089. |
the objective of this study was to assess if dhea can block the npy induced increase in food intake in lean and obese zucker rats. |
2007-03-06 |
2023-08-12 |
rat |
| Satoshi Mashiko, Akane Ishihara, Hisashi Iwaasa, Hideki Sano, Junko Ito, Akira Gomori, Zenjun Oda, Ryuichi Moriya, Hiroko Matsushita, Makoto Jitsuoka, Osamu Okamoto, Douglas J MacNeil, Lex H T Van der Ploeg, Takehiro Fukami, Akio Kanatan. A pair-feeding study reveals that a Y5 antagonist causes weight loss in diet-induced obese mice by modulating food intake and energy expenditure. Molecular pharmacology. vol 71. issue 2. 2007-03-01. PMID:17105869. |
we recently reported that an npy y5 antagonist inhibits body weight gain in diet-induced obese (dio) mice, with a moderate reduction in food intake. |
2007-03-01 |
2023-08-12 |
mouse |
| Dean A Van Vugt, Marla E Lujan, Mark Froats, Alicja Krzemien, Pastor R Couceyro, Robert L Rei. Effect of fasting on cocaine-amphetamine-regulated transcript, neuropeptide Y, and leptin receptor expression in the non-human primate hypothalamus. Neuroendocrinology. vol 84. issue 2. 2007-02-26. PMID:17124379. |
leptin inhibits food intake in rodents by inhibiting the orexigenic neuropetides neuropeptide y (npy) and agouti regulated peptide (agrp) and stimulating the anorexigenic neuropeptides alpha-melanocyte-stimulating hormone (alpha-msh) and cocaine-amphetamine-regulated transcript (cart). |
2007-02-26 |
2023-08-12 |
monkey |
| Elzbieta Sucajtys-Szulc, Joanna Karbowska, Zdzislaw Kochan, Wojciech Wolyniec, Michal Chmielewski, Boleslaw Rutkowski, Julian Swierczynsk. Up-regulation of NPY gene expression in hypothalamus of rats with experimental chronic renal failure. Biochimica et biophysica acta. vol 1772. issue 1. 2007-02-21. PMID:17011171. |
considering that: (a) npy is one of the most important stimulants of food intake; (b) eating is a central nervous system regulated process and (c) npy is expressed in hypothalamus, we hypothesized that the decrease of npy gene expression in the hypothalamus could be an important factor contributing to anorexia associated with uremic state. |
2007-02-21 |
2023-08-12 |
rat |
| Sameer N Goyal, Dadasaheb M Kokare, Chandrabhan T Chopde, Nishikant K Subheda. Alpha-melanocyte stimulating hormone antagonizes antidepressant-like effect of neuropeptide Y in Porsolt's test in rats. Pharmacology, biochemistry, and behavior. vol 85. issue 2. 2007-02-20. PMID:17052748. |
the physiological and functional interaction between neuropeptide y (npy) and alpha-melanocyte stimulating hormone (alpha-msh) with reference to anxiety and food intake is well documented. |
2007-02-20 |
2023-08-12 |
rat |
| Yih-Shou Hsieh, Shun-Fa Yang, Dong-Yih Ku. Intracerebral administration of protein kinase A or cAMP response element-binding protein antisense oligonucleotide can modulate amphetamine-mediated appetite suppression in free-moving rats. American journal of physiology. Endocrinology and metabolism. vol 292. issue 1. 2007-02-16. PMID:16896163. |
it is suggested that hypothalamic pka and creb signaling may involve the central regulation of amph-mediated feeding suppression via the modulation of npy gene expression. |
2007-02-16 |
2023-08-12 |
rat |
| Timothy H Moran, Sheng B. Hyperphagia and obesity in OLETF rats lacking CCK-1 receptors. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 361. issue 1471. 2007-02-15. PMID:16815799. |
in intact rats npy and cck-1 receptors colocalize to neurons within the compact subregion of the dmh and local cck administration reduces food intake and decreases dmh npy mrna expression. |
2007-02-15 |
2023-08-12 |
rat |
| B Bec. Neuropeptide Y in normal eating and in genetic and dietary-induced obesity. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 361. issue 1471. 2007-02-15. PMID:16874931. |
the npy system for feeding regulation is mostly located in the hypothalamus. |
2007-02-15 |
2023-08-12 |
mouse |
| B Bec. Neuropeptide Y in normal eating and in genetic and dietary-induced obesity. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 361. issue 1471. 2007-02-15. PMID:16874931. |
finally, npy appears to play an important role in body weight and feeding regulation, and while it does not constitute the only target for drug treatment of obesity, it may nevertheless provide a useful target in conjunction with others. |
2007-02-15 |
2023-08-12 |
mouse |
| Vittorio Coiro, Gloria Saccani-Jotti, Pasquale Rubino, Guido Manfredi, Andrea Melani, Paolo Chioder. Effects of ghrelin on circulating neuropeptide Y levels in humans. Neuro endocrinology letters. vol 27. issue 6. 2007-02-15. PMID:17187020. |
neuropeptide y (npy) is a well-known stimulator of pathways favouring food intake and energy storage. |
2007-02-15 |
2023-08-12 |
Not clear |
| Eva Szentirmai, Levente Kapás, James M Kruege. Ghrelin microinjection into forebrain sites induces wakefulness and feeding in rats. American journal of physiology. Regulatory, integrative and comparative physiology. vol 292. issue 1. 2007-02-08. PMID:16917015. |
in the brain, orexin, neuropeptide y (npy), and ghrelin are parts of a food intake regulatory circuit. |
2007-02-08 |
2023-08-12 |
rat |
| Björn Meister, Burçak Gömüç, Elisabet Suarez, Yuko Ishii, Katrin Dürr, Linda Gillber. Hypothalamic proopiomelanocortin (POMC) neurons have a cholinergic phenotype. The European journal of neuroscience. vol 24. issue 10. 2007-01-30. PMID:17156199. |
neuropeptide y (npy)-producing neurons in the arcuate nucleus stimulate food intake, whereas arcuate nucleus neurons that release the proopiomelanocortin (pomc)-derived peptide alpha-melanocyte-stimulating hormone (alpha-msh) potently reduce food intake. |
2007-01-30 |
2023-08-12 |
rat |
| Sarika Arora, Anubhut. Role of neuropeptides in appetite regulation and obesity--a review. Neuropeptides. vol 40. issue 6. 2007-01-18. PMID:16935329. |
the structure and function of many hypothalamic peptides (neuropeptide y (npy), melanocortins, agouti-related peptide (agrp), cocaine and amphetamine regulated transcript (cart), melanin concentrating hormone (mch), orexins have been characterized in rodent models the peripheral neuropeptides such as cholecystokinin (cck), ghrelin, peptide yy (pyy3-36), amylin, bombesin regulate important gastrointestinal functions such as motility, secretion, absorption, provide feedback to the central nervous system on availability of nutrients and may play a part in regulating food intake. |
2007-01-18 |
2023-08-12 |
Not clear |
| Matti K Karvonen, Soile Ruottinen, Markku Koulu, Ullamari Pesonen, Harri Niinikoski, Leena Rask-Nissilä, Olli Simell, Tapani Rönnema. Nutrient intake, weight, and Leu7Pro polymorphism in prepro-neuropeptide Y in children. The Journal of clinical endocrinology and metabolism. vol 91. issue 11. 2007-01-12. PMID:16912140. |
the important role of neuropeptide y (npy) in the regulation of food intake and energy balance has been firmly documented in rodents, but human data are sparse. |
2007-01-12 |
2023-08-12 |
human |
| Sue Ritter, Thu T Dinh, Ai-Jun L. Hindbrain catecholamine neurons control multiple glucoregulatory responses. Physiology & behavior. vol 89. issue 4. 2007-01-04. PMID:16887153. |
epinephrine or ne neurons co-expressing neuropeptide y (npy) may be the neuronal phenotype required for glucoprivic feeding: they increase npy mrna expression in response to glucoprivation and are nearly eliminated by dsap injections that abolish glucoprivic feeding. |
2007-01-04 |
2023-08-12 |
Not clear |
| Sue Ritter, Thu T Dinh, Ai-Jun L. Hindbrain catecholamine neurons control multiple glucoregulatory responses. Physiology & behavior. vol 89. issue 4. 2007-01-04. PMID:16887153. |
in contrast, lesion of arcuate nucleus npy neurons, using the toxin, npy-saporin, does not impair glucoprivic feeding or hyperglycemic responses. |
2007-01-04 |
2023-08-12 |
Not clear |
| Hiralben R Patel, Yong Qi, Evan J Hawkins, Stanley M Hileman, Joel K Elmquist, Yumi Imai, Rexford S Ahim. Neuropeptide Y deficiency attenuates responses to fasting and high-fat diet in obesity-prone mice. Diabetes. vol 55. issue 11. 2007-01-04. PMID:17065347. |
neuropeptide y (npy) stimulates feeding and weight gain, but deletion of the npy gene does not affect food intake and body weight in mice bred on a mixed genetic background. |
2007-01-04 |
2023-08-12 |
mouse |
| Dong-Yih Ku. Hypothalamic neuropeptide Y (NPY) and the attenuation of hyperphagia in streptozotocin diabetic rats treated with dopamine D1/D2 agonists. British journal of pharmacology. vol 148. issue 5. 2006-12-26. PMID:16702993. |
changes in food intake and hypothalamic npy content of these rats were assessed and compared. |
2006-12-26 |
2023-08-12 |
rat |
| Carola Eva, Alessandra Oberto, Paolo Mele, Mariangela Serra, Giovanni Biggi. Role of brain neuroactive steroids in the functional interplay between the GABA(A) and the NPY-Y1 receptor mediated signals in the amygdala. Pharmacology, biochemistry, and behavior. vol 84. issue 4. 2006-12-20. PMID:16824587. |
various lines of evidence suggest a functional interaction between gaba(a) and neuropeptide y (npy)-y(1) receptor (y(1)r) mediated transmissions in various brain regions, which can be important in the regulation of sedation, feeding, anxious behaviour and neuronal excitability. |
2006-12-20 |
2023-08-12 |
mouse |
| Elizabeth F Gluck, Natalie Stephens, Steven J Swoa. Peripheral ghrelin deepens torpor bouts in mice through the arcuate nucleus neuropeptide Y signaling pathway. American journal of physiology. Regulatory, integrative and comparative physiology. vol 291. issue 5. 2006-11-29. PMID:16825418. |
two major pathways that regulate food intake reside in the arc, the anorexigenic alpha-melanocyte stimulating hormone (alpha-msh) pathway and the orexigenic neuropeptide y (npy) signaling pathway. |
2006-11-29 |
2023-08-12 |
mouse |