| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daisuke Kohno, Hideyuki Sone, Yasuhiko Minokoshi, Toshihiko Yad. Ghrelin raises [Ca2+]i via AMPK in hypothalamic arcuate nucleus NPY neurons. Biochemical and biophysical research communications. vol 366. issue 2. 2008-02-05. PMID:18068666. |
ghrelin, an orexigenic hormone, directly activates neuropeptide (npy) neurons in the hypothalamic arcuate nucleus (arc), and thereby stimulates food intake. |
2008-02-05 |
2023-08-12 |
Not clear |
| P R Lingo, Z Zhao, P She. Co-regulation of cold-resistant food acquisition by insulin- and neuropeptide Y-like systems in Drosophila melanogaster. Neuroscience. vol 148. issue 2. 2008-01-25. PMID:17658221. |
genetic analyses reveal that the neural activity of npfr1, a receptor of neuropeptide f (npf, the sole fly homolog of neuropeptide y or npy), was required for cold-resistant feeding behavior of fasted larvae. |
2008-01-25 |
2023-08-12 |
drosophila_melanogaster |
| Birgitte Tiesjema, Roger A H Adan, Mieneke C M Luijendijk, Andries Kalsbeek, Susanne E la Fleu. Differential effects of recombinant adeno-associated virus-mediated neuropeptide Y overexpression in the hypothalamic paraventricular nucleus and lateral hypothalamus on feeding behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 51. 2008-01-14. PMID:18094253. |
it is well known that neuropeptide y (npy) increases food intake. |
2008-01-14 |
2023-08-12 |
rat |
| Birgitte Tiesjema, Roger A H Adan, Mieneke C M Luijendijk, Andries Kalsbeek, Susanne E la Fleu. Differential effects of recombinant adeno-associated virus-mediated neuropeptide Y overexpression in the hypothalamic paraventricular nucleus and lateral hypothalamus on feeding behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 51. 2008-01-14. PMID:18094253. |
although it is obvious that increased energy intake may lead to obesity, it is less understood which aspects of feeding behavior are affected and whether one or multiple neural sites mediate the effects of long-term increased npy signaling. |
2008-01-14 |
2023-08-12 |
rat |
| Birgitte Tiesjema, Roger A H Adan, Mieneke C M Luijendijk, Andries Kalsbeek, Susanne E la Fleu. Differential effects of recombinant adeno-associated virus-mediated neuropeptide Y overexpression in the hypothalamic paraventricular nucleus and lateral hypothalamus on feeding behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 51. 2008-01-14. PMID:18094253. |
by long-term overexpressing npy in either the pvn or the lh, we uncovered brain site-specific effects of npy on meal frequency, meal size, and diurnal feeding patterns. |
2008-01-14 |
2023-08-12 |
rat |
| A Gyte, L E Pritchard, H B Jones, J C Brennand, A Whit. Reduced expression of the KATP channel subunit, Kir6.2, is associated with decreased expression of neuropeptide Y and agouti-related protein in the hypothalami of Zucker diabetic fatty rats. Journal of neuroendocrinology. vol 19. issue 12. 2008-01-02. PMID:18001323. |
the hypothalamic neuropeptides, pro-opiomelanocortin (pomc), neuropeptide y (npy) and agouti-related protein (agrp) are central to the regulation of food intake and have been implicated in glucose homeostasis. |
2008-01-02 |
2023-08-12 |
rat |
| Su Gao, Kimberly P Kinzig, Susan Aja, Karen A Scott, Wendy Keung, Sandra Kelly, Ken Strynadka, Shigeru Chohnan, Wanli W Smith, Kellie L K Tamashiro, Ellen E Ladenheim, Gabriele V Ronnett, Yajun Tu, Morris J Birnbaum, Gary D Lopaschuk, Timothy H Mora. Leptin activates hypothalamic acetyl-CoA carboxylase to inhibit food intake. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 44. 2007-12-27. PMID:17956983. |
inhibiting hypothalamic acc with 5-tetradecyloxy-2-furoic acid, a specific acc inhibitor, blocks leptin-mediated decreases in food intake, body weight, and mrna level of the orexigenic neuropeptide npy. |
2007-12-27 |
2023-08-12 |
Not clear |
| P C Konturek, J W Konturek, M Cześnikiewicz-Guzik, T Brzozowski, E Sito, S J Konture. Neuro-hormonal control of food intake: basic mechanisms and clinical implications. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 56 Suppl 6. 2007-12-18. PMID:16340035. |
there are two distinct types of neurons in arc that are important in control of food intake; (1) preopiomelanocortin (pomc) neurons activated by an orexigenic hormones and releasing alpha-melanocyte-stimulating hormone (alpha-msh) in satiety center and (2) neurons activated by orexigenic peptides such as ghrelin that release the substances including neuropeptide y (npy) and agouti-related peptide (agrp) in hunger center. |
2007-12-18 |
2023-08-12 |
Not clear |
| Yih-Shou Hsieh, Shun-Fa Yang, Shu-Chen Chu, Dong-Yih Ku. Transcript of protein kinase A knock-down modulates feeding behavior and neuropeptide Y gene expression in phenylpropanolamine-treated rats. Physiological genomics. vol 31. issue 2. 2007-12-13. PMID:17684035. |
changes in daily food intake and hypothalamic npy, pka, camp response element binding protein (creb), and pro-opiomelanocortin (pomc) gene expression were measured and compared. |
2007-12-13 |
2023-08-12 |
rat |
| Yih-Shou Hsieh, Shun-Fa Yang, Shu-Chen Chu, Dong-Yih Ku. Transcript of protein kinase A knock-down modulates feeding behavior and neuropeptide Y gene expression in phenylpropanolamine-treated rats. Physiological genomics. vol 31. issue 2. 2007-12-13. PMID:17684035. |
results showed that daily pka, creb, and pomc expression were increased following ppa treatment, which showed a closely reverse relationship with alterations of decreased feeding behaviors and npy mrna levels. |
2007-12-13 |
2023-08-12 |
rat |
| Gui-Qian Chen, Xiu-Fang Hu, Kunio Sugahara, Ji-Shuang Chen, Xue-Mei Song, Hui-Chao Zheng, Yong-Qing Jiang, Xin Huang, Jun-Fang Jiang, Wei-Dong Zho. Type-dependent differential expression of neuropeptide Y in chicken hypothalamus (Gallus domesticus). Journal of Zhejiang University. Science. B. vol 8. issue 11. 2007-12-06. PMID:17973346. |
neuropeptide y (npy) is one of the most important orexigenic agents in central regulation of feeding behavior, body weight and energy homeostasis in domestic chickens. |
2007-12-06 |
2023-08-12 |
chicken |
| Gui-Qian Chen, Xiu-Fang Hu, Kunio Sugahara, Ji-Shuang Chen, Xue-Mei Song, Hui-Chao Zheng, Yong-Qing Jiang, Xin Huang, Jun-Fang Jiang, Wei-Dong Zho. Type-dependent differential expression of neuropeptide Y in chicken hypothalamus (Gallus domesticus). Journal of Zhejiang University. Science. B. vol 8. issue 11. 2007-12-06. PMID:17973346. |
to examine differences in the hypothalamic npy between layer-type and meat-type of chickens, which are two divergent kinds of the domestic chickens in feeding behavior and body weight, we detected mrna levels of npy in hypothalamic infundibular nucleus (in), paraventricular nucleus (pvn) and lateral hypothalamic area (lha) of these two types of chickens using one-step real time rt-pcr. |
2007-12-06 |
2023-08-12 |
chicken |
| M M Kamiji, A Inu. Neuropeptide y receptor selective ligands in the treatment of obesity. Endocrine reviews. vol 28. issue 6. 2007-11-27. PMID:17785427. |
within the hypothalamus, npy plays an essential role in the control of food intake and body weight. |
2007-11-27 |
2023-08-12 |
human |
| M M Kamiji, A Inu. Neuropeptide y receptor selective ligands in the treatment of obesity. Endocrine reviews. vol 28. issue 6. 2007-11-27. PMID:17785427. |
centrally administered npy causes robust increases in food intake and body weight and, with chronic administration, can eventually produce obesity. |
2007-11-27 |
2023-08-12 |
human |
| Xu-Fang Liang, Guang-Zhao Li, Wei Yao, Lai-Wan Cheong, Wan-Qin Lia. Molecular characterization of neuropeptide Y gene in Chinese perch, an acanthomorph fish. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. vol 148. issue 1. 2007-11-20. PMID:17537656. |
these results indicated that chinese perch npy might be involved in the food intake control by leptin and cortisol system, and diversification of npy signaling should exist between acanthomorph fishes and cyprinid fishes as well as mammals. |
2007-11-20 |
2023-08-12 |
rat |
| Yih-Shou Hsieh, Shun-Fa Yang, Hui-Ling Chiou, Dong-Yih Ku. Roles of central catecholamine and hypothalamic neuropeptide Y genome in the development of tolerance to phenylpropanolamine-mediated appetite suppression. Behavioral neuroscience. vol 121. issue 5. 2007-11-20. PMID:17907825. |
moreover, results also revealed that the alteration in npy messenger rna level coincided with the change of feeding behavior during ppa treatment and that infusions of npy antisense oligonucleotide into the cerebroventricle abolished the effect of ppa tolerance. |
2007-11-20 |
2023-08-12 |
cat |
| ChuanFeng Wang, Eric Bomberg, Allen Levine, Charles Billington, Catherine M Kot. Brain-derived neurotrophic factor in the ventromedial nucleus of the hypothalamus reduces energy intake. American journal of physiology. Regulatory, integrative and comparative physiology. vol 293. issue 3. 2007-10-17. PMID:17553842. |
we evaluated the effect of bdnf, given into the ventromedial nucleus of the hypothalamus (vmh), on normal and deprivation- and neuropeptide y (npy)-induced feeding behavior and body weight. |
2007-10-17 |
2023-08-12 |
rat |
| ChuanFeng Wang, Eric Bomberg, Charles Billington, Allen Levine, Catherine M Kot. Brain-derived neurotrophic factor in the hypothalamic paraventricular nucleus reduces energy intake. American journal of physiology. Regulatory, integrative and comparative physiology. vol 293. issue 3. 2007-10-17. PMID:17581841. |
pvn bdnf significantly decreased pvn neuropeptide y (npy)-induced feeding at 1, 2, and 4 h following injection. |
2007-10-17 |
2023-08-12 |
rat |
| Jaroslaw Staszkiewicz, Ronald Horswell, George Argyropoulo. Chronic consumption of a low-fat diet leads to increased hypothalamic agouti-related protein and reduced leptin. Nutrition (Burbank, Los Angeles County, Calif.). vol 23. issue 9. 2007-10-11. PMID:17643264. |
this study examined the hypothesis that dietary fat under ad libitum feeding conditions influences expression levels (mrna) of the mouse agouti-related protein (agrp), leptin, leptin receptor (obrb), and neuropeptide y (npy) at early stages of development. |
2007-10-11 |
2023-08-12 |
mouse |
| Nianhong Yang, Chongjian Wang, Mingjia Xu, Limei Mao, Liegang Liu, Xiufa Su. Interaction of dietary composition and PYY gene expression in diet-induced obesity in rats. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 25. issue 3. 2007-10-02. PMID:16201260. |
weight gain and food intake were measured, food efficiency was calculated, and the concentrations of plasma neuropeptide y (npy) and pyy were assayed. |
2007-10-02 |
2023-08-12 |
rat |