| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| James R C Parkinson, Waljit S Dhillo, Caroline J Small, Owais B Chaudhri, Gavin A Bewick, Iain Pritchard, Stanley Moore, Mohammed A Ghatei, Stephen R Bloo. PYY3-36 injection in mice produces an acute anorexigenic effect followed by a delayed orexigenic effect not observed with other anorexigenic gut hormones. American journal of physiology. Endocrinology and metabolism. vol 294. issue 4. 2008-05-22. PMID:18285527. |
pyy(3-36), the major circulating form of the peptide, is thought to reduce food intake in humans and rodents via high-affinity binding to the autoinhibitory neuropeptide y (npy) receptor within the arcuate nucleus. |
2008-05-22 |
2023-08-12 |
mouse |
| E Salaneck, T A Larsson, E T Larson, D Larhamma. Birth and death of neuropeptide Y receptor genes in relation to the teleost fish tetraploidization. Gene. vol 409. issue 1-2. 2008-05-20. PMID:18191918. |
the unexpected absence of the two appetite-stimulating receptors y(1) and y(5) in some euteleosts, along with our discovery of duplicates of the peptide ligands npy and pyy, has implications for the role of the npy system in euteleost feeding behavior. |
2008-05-20 |
2023-08-12 |
zebrafish |
| Rinko Kawagoe, Yukiyo Yamamoto, Kazuyasu Kubo, Kazushige Dobashi, Kohtaro Asayama, Yoichi Ueta, Akira Shirahat. Postnatal development of galanin-like peptide mRNA expression in rat hypothalamus. Regulatory peptides. vol 145. issue 1-3. 2008-05-06. PMID:17950941. |
neuropeptide y (npy) and proopiomelanocortin (pomc) mrna in the hypothalamus were also examined because they are important in the regulation of food intake. |
2008-05-06 |
2023-08-12 |
rat |
| Karolina Bojkowska, Magdalena M Hamczyk, Houng-Wei Tsai, Anna Riggan, Emilie F Rissma. Neuropeptide Y influences acute food intake and energy status affects NPY immunoreactivity in the female musk shrew (Suncus murinus). Hormones and behavior. vol 53. issue 2. 2008-05-06. PMID:18191134. |
neuropeptide y influences acute food intake and energy status affects npy immunoreactivity in the female musk shrew (suncus murinus). |
2008-05-06 |
2023-08-12 |
Not clear |
| Karolina Bojkowska, Magdalena M Hamczyk, Houng-Wei Tsai, Anna Riggan, Emilie F Rissma. Neuropeptide Y influences acute food intake and energy status affects NPY immunoreactivity in the female musk shrew (Suncus murinus). Hormones and behavior. vol 53. issue 2. 2008-05-06. PMID:18191134. |
neuropeptide y (npy) stimulates feeding, depresses sexual behavior, and its expression in the brain is modulated by energetic status. |
2008-05-06 |
2023-08-12 |
Not clear |
| Karolina Bojkowska, Magdalena M Hamczyk, Houng-Wei Tsai, Anna Riggan, Emilie F Rissma. Neuropeptide Y influences acute food intake and energy status affects NPY immunoreactivity in the female musk shrew (Suncus murinus). Hormones and behavior. vol 53. issue 2. 2008-05-06. PMID:18191134. |
intracerebroventricular infusion of npy enhanced acute food intake in shrews; however, npy had little affect on sexual receptivity. |
2008-05-06 |
2023-08-12 |
Not clear |
| Karolina Bojkowska, Magdalena M Hamczyk, Houng-Wei Tsai, Anna Riggan, Emilie F Rissma. Neuropeptide Y influences acute food intake and energy status affects NPY immunoreactivity in the female musk shrew (Suncus murinus). Hormones and behavior. vol 53. issue 2. 2008-05-06. PMID:18191134. |
in two midbrain regions, both of which contain high levels of gonadotropin releasing hormone ii (gnrh ii), which has anorexigenic actions in shrews, npy immunoreactivity was more sensitive to changes in food intake. |
2008-05-06 |
2023-08-12 |
Not clear |
| Coralia Pérez, Teresa Fernández-Agulló, Alain J De Solís, Manuel Ros, Antonio Andrés, José M Carrascos. Effects of chronic acarbose treatment on adipocyte insulin responsiveness, serum levels of leptin and adiponectin and hypothalamic NPY expression in obese diabetic Wistar rats. Clinical and experimental pharmacology & physiology. vol 35. issue 3. 2008-04-29. PMID:18290871. |
in the present study, we have investigated the effect of 3 months treatment with acarbose on adiposity, food intake and the modulation of hypothalamic neuropeptide y (npy) in obese diabetic wistar (wdf) rats and the possible correlation between changes in overall insulin sensitivity and the level of circulating adipokines, leptin and adiponectin. |
2008-04-29 |
2023-08-12 |
rat |
| Coralia Pérez, Teresa Fernández-Agulló, Alain J De Solís, Manuel Ros, Antonio Andrés, José M Carrascos. Effects of chronic acarbose treatment on adipocyte insulin responsiveness, serum levels of leptin and adiponectin and hypothalamic NPY expression in obese diabetic Wistar rats. Clinical and experimental pharmacology & physiology. vol 35. issue 3. 2008-04-29. PMID:18290871. |
although food intake was not significantly reduced in rats treated with acarbose, the acarbose-treated rats had lower npy expression in the arcuate nucleus. |
2008-04-29 |
2023-08-12 |
rat |
| Coralia Pérez, Teresa Fernández-Agulló, Alain J De Solís, Manuel Ros, Antonio Andrés, José M Carrascos. Effects of chronic acarbose treatment on adipocyte insulin responsiveness, serum levels of leptin and adiponectin and hypothalamic NPY expression in obese diabetic Wistar rats. Clinical and experimental pharmacology & physiology. vol 35. issue 3. 2008-04-29. PMID:18290871. |
acarbose neither decreases food intake nor reverts obesity, but decreases leptin levels and the expression of the orexigenic npy in the hypothalamus. |
2008-04-29 |
2023-08-12 |
rat |
| Kousaku Ohinata, Kuniko Takagi, Kyoko Biyajima, Yoko Fujiwara, Shingo Fukumoto, Naomi Eguchi, Yoshihiro Urade, Akihiro Asakawa, Mineko Fujimiya, Akio Inui, Masaaki Yoshikaw. Central prostaglandin D(2) stimulates food intake via the neuropeptide Y system in mice. FEBS letters. vol 582. issue 5. 2008-04-24. PMID:18258196. |
taken together, pgd(2) may stimulate food intake through central dp(1) receptor coupled to the npy system. |
2008-04-24 |
2023-08-12 |
mouse |
| Denise D Belsha. Hormonal regulation of clonal, immortalized hypothalamic neurons expressing neuropeptides involved in reproduction and feeding. Molecular neurobiology. vol 35. issue 2. 2008-04-04. PMID:17917107. |
a number of these neuronal cell lines express neuropeptides linked to the control of feeding behavior and reproduction, including neuropeptide y (npy) and neurotensin (nt). |
2008-04-04 |
2023-08-12 |
Not clear |
| Colin T Phillips, Richard D Palmite. Role of agouti-related protein-expressing neurons in lactation. Endocrinology. vol 149. issue 2. 2008-03-27. PMID:17974621. |
hypothalamic neurons that express agouti-related protein (agrp) and neuropeptide y (npy) are thought to be important for regulation of feeding, especially under conditions of negative energy balance. |
2008-03-27 |
2023-08-12 |
mouse |
| John-Paul Baird, Catalina Rios, Jasmine L Loveland, Janine Beck, Alice Tran, Carrie E Mahone. Effects of hindbrain melanin-concentrating hormone and neuropeptide Y administration on licking for water, saccharin, and sucrose solutions. American journal of physiology. Regulatory, integrative and comparative physiology. vol 294. issue 2. 2008-03-27. PMID:17989139. |
the effects of fourth ventricle (4v) infusions of npy (5 microg) and mch (5 microg) on licking for water, 4 mm saccharin, and sucrose (0.1 and 1.0 m) solutions were compared to identify the contributions of each peptide to hindbrain-stimulated feeding. |
2008-03-27 |
2023-08-12 |
Not clear |
| John-Paul Baird, Catalina Rios, Jasmine L Loveland, Janine Beck, Alice Tran, Carrie E Mahone. Effects of hindbrain melanin-concentrating hormone and neuropeptide Y administration on licking for water, saccharin, and sucrose solutions. American journal of physiology. Regulatory, integrative and comparative physiology. vol 294. issue 2. 2008-03-27. PMID:17989139. |
the dissociation between mch and npy effects observed for 4v injections is consistent with reports that forebrain icv injections of mch and npy produced nearly dichotomous effects on the pattern of licking microstructure, and, collectively, the results indicate that the two peptides have separate sites of feeding action in the brain. |
2008-03-27 |
2023-08-12 |
Not clear |
| Bernard Beck, Sebastien Richy, Alain Stricker-Krongra. Responsiveness of obese Zucker rats to [D-Trp34]-NPY supports the targeting of Y5 receptor for obesity treatment. Nutritional neuroscience. vol 10. issue 5-6. 2008-03-20. PMID:18284029. |
they support the role of the neuropeptide y5 receptor in the regulation of food intake and suggest that npy y5 antagonism might be useful for treating obesity. |
2008-03-20 |
2023-08-12 |
rat |
| Praveen Vats, Vijay Kumar Singh, Som Nath Singh, Shashi Bala Sing. High altitude induced anorexia: effect of changes in leptin and oxidative stress levels. Nutritional neuroscience. vol 10. issue 5-6. 2008-03-20. PMID:18284032. |
in present study effect of ha exposure on levels of leptin and npy was evaluated along with n-acetyl cysteine (nac) and vitamin e supplementation in relation to food intake and body weight changes. |
2008-03-20 |
2023-08-12 |
human |
| Hui Chen, Michelle J Hansen, Jessica E Jones, Ross Vlahos, Gary P Anderson, Margaret J Morri. Detrimental metabolic effects of combining long-term cigarette smoke exposure and high-fat diet in mice. American journal of physiology. Endocrinology and metabolism. vol 293. issue 6. 2008-02-25. PMID:17940214. |
neuropeptide y (npy) is a powerful hypothalamic feeding stimulator that promotes obesity. |
2008-02-25 |
2023-08-12 |
mouse |
| Sara Xapelli, Fabienne Agasse, Raquel Ferreira, Ana P Silva, João O Malv. Neuropeptide Y as an endogenous antiepileptic, neuroprotective and pro-neurogenic peptide. Recent patents on CNS drug discovery. vol 1. issue 3. 2008-02-15. PMID:18221213. |
neuropeptide y (npy) is a small peptide important in cardiovascular physiology, feeding, anxiety, depression and epilepsy. |
2008-02-15 |
2023-08-12 |
Not clear |
| M Ruscica, E Dozio, M Motta, P Magn. Relevance of the neuropeptide Y system in the biology of cancer progression. Current topics in medicinal chemistry. vol 7. issue 17. 2008-02-05. PMID:17979777. |
within this family of peptides, npy, a highly conserved 36-aminoacid residue peptide, is involved in the regulation of a wide range of physiological functions, such as food intake and energy metabolism, as well as in the promotion of some remarkable aspects of tumor progression, including cell proliferation, matrix invasion, metastatization, and angiogenesis. |
2008-02-05 |
2023-08-12 |
Not clear |