| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Liang Yang, Karen A Scott, Jayson Hyun, Kellie L Tamashiro, Nancy Tray, Timothy H Moran, Sheng B. Role of dorsomedial hypothalamic neuropeptide Y in modulating food intake and energy balance. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 1. 2009-04-08. PMID:19129396. |
to elucidate such actions, we used the adenoassociated virus (aav) system to alter npy gene expression in the dmh and examined the effects of these alterations on food intake and energy balance as well as explored its downstream signaling pathway. |
2009-04-08 |
2023-08-12 |
rat |
| Liang Yang, Karen A Scott, Jayson Hyun, Kellie L Tamashiro, Nancy Tray, Timothy H Moran, Sheng B. Role of dorsomedial hypothalamic neuropeptide Y in modulating food intake and energy balance. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 1. 2009-04-08. PMID:19129396. |
we found that aav-mediated overexpression of npy in the dmh of lean rats increased food intake and body weight, and exacerbated high-fat diet-induced obesity. |
2009-04-08 |
2023-08-12 |
rat |
| Liang Yang, Karen A Scott, Jayson Hyun, Kellie L Tamashiro, Nancy Tray, Timothy H Moran, Sheng B. Role of dorsomedial hypothalamic neuropeptide Y in modulating food intake and energy balance. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 1. 2009-04-08. PMID:19129396. |
npy knockdown in the dmh produced a nocturnal and meal size-specific feeding effect. |
2009-04-08 |
2023-08-12 |
rat |
| Liang Yang, Karen A Scott, Jayson Hyun, Kellie L Tamashiro, Nancy Tray, Timothy H Moran, Sheng B. Role of dorsomedial hypothalamic neuropeptide Y in modulating food intake and energy balance. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 1. 2009-04-08. PMID:19129396. |
dmh npy knockdown increased the feeding inhibitory and nts c-fos responses to peripheral administration of cholecystokinin. |
2009-04-08 |
2023-08-12 |
rat |
| Liang Yang, Karen A Scott, Jayson Hyun, Kellie L Tamashiro, Nancy Tray, Timothy H Moran, Sheng B. Role of dorsomedial hypothalamic neuropeptide Y in modulating food intake and energy balance. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 1. 2009-04-08. PMID:19129396. |
together, these results indicate that dmh npy plays an important role in modulating food intake and energy balance and its dysregulation causes disordered energy balance leading to obesity. |
2009-04-08 |
2023-08-12 |
rat |
| Ai-Jun Li, Qing Wang, Thu T Dinh, Sue Ritte. Simultaneous silencing of Npy and Dbh expression in hindbrain A1/C1 catecholamine cells suppresses glucoprivic feeding. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 1. 2009-04-08. PMID:19129404. |
simultaneous silencing of npy and dbh expression in hindbrain a1/c1 catecholamine cells suppresses glucoprivic feeding. |
2009-04-08 |
2023-08-12 |
Not clear |
| Ai-Jun Li, Qing Wang, Thu T Dinh, Sue Ritte. Simultaneous silencing of Npy and Dbh expression in hindbrain A1/C1 catecholamine cells suppresses glucoprivic feeding. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 1. 2009-04-08. PMID:19129404. |
previous data have strongly implicated hindbrain catecholamine/neuropeptide y (npy) coexpressing neurons as key mediators of the glucoprivic feeding response. |
2009-04-08 |
2023-08-12 |
Not clear |
| Ai-Jun Li, Qing Wang, Thu T Dinh, Sue Ritte. Simultaneous silencing of Npy and Dbh expression in hindbrain A1/C1 catecholamine cells suppresses glucoprivic feeding. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 1. 2009-04-08. PMID:19129404. |
silencing of either npy or dbh alone did not reduce glucoprivic feeding or hyperglycemic responses, compared with responses of ntrna-injected controls. |
2009-04-08 |
2023-08-12 |
Not clear |
| Ai-Jun Li, Qing Wang, Thu T Dinh, Sue Ritte. Simultaneous silencing of Npy and Dbh expression in hindbrain A1/C1 catecholamine cells suppresses glucoprivic feeding. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 1. 2009-04-08. PMID:19129404. |
in contrast, simultaneous silencing of both npy and dbh reduced 2dg-induced feeding by 61%. |
2009-04-08 |
2023-08-12 |
Not clear |
| Hiroshi Higuchi, Takeshi Niki, Tomohiro Shiiy. Feeding behavior and gene expression of appetite-related neuropeptides in mice lacking for neuropeptide Y Y5 receptor subclass. World journal of gastroenterology. vol 14. issue 41. 2009-04-03. PMID:19009645. |
neuropeptide y (npy) is a potent neurotransmitter for feeding. |
2009-04-03 |
2023-08-12 |
mouse |
| Hiroshi Higuchi, Takeshi Niki, Tomohiro Shiiy. Feeding behavior and gene expression of appetite-related neuropeptides in mice lacking for neuropeptide Y Y5 receptor subclass. World journal of gastroenterology. vol 14. issue 41. 2009-04-03. PMID:19009645. |
besides npy, orexigenic neuropeptides such as agouti-related protein (agrp), and anorexigenic neuropeptides such as alpha-melatonin stimulating hormone (msh) and cocaine-amphetamine-regulated transcript (cart) are also involved in central feeding regulation. |
2009-04-03 |
2023-08-12 |
mouse |
| Hiroshi Higuchi, Takeshi Niki, Tomohiro Shiiy. Feeding behavior and gene expression of appetite-related neuropeptides in mice lacking for neuropeptide Y Y5 receptor subclass. World journal of gastroenterology. vol 14. issue 41. 2009-04-03. PMID:19009645. |
to clarify the compensatory mechanism of knock-out of npy system on feeding, change in gene expressions of appetite-related neuropeptides and the feeding behavior was studied in npy y5-ko mice. |
2009-04-03 |
2023-08-12 |
mouse |
| Daisuke Kohno, Shigetomo Suyama, Toshihiko Yad. Leptin transiently antagonizes ghrelin and long-lastingly orexin in regulation of Ca2+ signaling in neuropeptide Y neurons of the arcuate nucleus. World journal of gastroenterology. vol 14. issue 41. 2009-04-03. PMID:19009650. |
to explore the mechanism for interactions of leptin with ghrelin and orexin in the arcuate nucleus (arc) activating neuropeptide y (npy) neurons during physiological regulation of feeding. |
2009-04-03 |
2023-08-12 |
Not clear |
| Dong-Yih Kuo, Shun-Fa Yang, Shu-Chen Chu, Chin-Hsiu Chen, Yih-Shou Hsie. Roles of protein kinase Calpha isozyme in the regulation of oxidative stress and neuropeptide Y gene expression in phenylpropanolamine-mediated appetite suppression. Journal of neurochemistry. vol 108. issue 6. 2009-04-02. PMID:19183253. |
changes in food intake, hypothalamic npy, pkc, and proopiomelanocortin (pomc) mrna levels were assessed and compared. |
2009-04-02 |
2023-08-12 |
rat |
| Dong-Yih Kuo, Shun-Fa Yang, Shu-Chen Chu, Chin-Hsiu Chen, Yih-Shou Hsie. Roles of protein kinase Calpha isozyme in the regulation of oxidative stress and neuropeptide Y gene expression in phenylpropanolamine-mediated appetite suppression. Journal of neurochemistry. vol 108. issue 6. 2009-04-02. PMID:19183253. |
results showed that the npy gene was down-regulated following ppa treatment, which was parallel with the decrease of feeding. |
2009-04-02 |
2023-08-12 |
rat |
| Li Shen, Michael J Keenan, Roy J Martin, Richard T Tulley, Anne M Raggio, Kathleen L McCutcheon, Jun Zho. Dietary resistant starch increases hypothalamic POMC expression in rats. Obesity (Silver Spring, Md.). vol 17. issue 1. 2009-03-24. PMID:18948970. |
at the end of study, body fat, food intake, plasma peptide yy (pyy) and glucagon-like peptide 1 (glp-1), and hypothalamic pro-opiomelanocortin (pomc), neuropeptide y (npy), agouti-related peptide (agrp) gene expressions were measured. |
2009-03-24 |
2023-08-12 |
rat |
| Mary W Walker, Toni D Wolinsky, Vrej Jubian, Gamini Chandrasena, Huailing Zhong, Xinyan Huang, Silke Miller, Laxminarayan G Hegde, Douglas A Marsteller, Mohammad R Marzabadi, Mariusz Papp, David H Overstreet, Christophe P G Gerald, Douglas A Crai. The novel neuropeptide Y Y5 receptor antagonist Lu AA33810 [N-[[trans-4-[(4,5-dihydro[1]benzothiepino[5,4-d]thiazol-2-yl)amino]cyclohexyl]methyl]-methanesulfonamide] exerts anxiolytic- and antidepressant-like effects in rat models of stress sensitivity. The Journal of pharmacology and experimental therapeutics. vol 328. issue 3. 2009-03-24. PMID:19098165. |
blocked feeding elicited by intracerebroventricular injection of the y(5) receptor-selective agonist [cpp(1-7),npy(19-23),ala(31),aib(32),gln(34)]-hpancreatic polypeptide in sprague-dawley rats. |
2009-03-24 |
2023-08-12 |
rat |
| Bojlul Bahar, Torres Sweene. Mapping of the transcription start site (TSS) and identification of SNPs in the bovine neuropeptide Y (NPY) gene. BMC genetics. vol 9. 2009-03-23. PMID:19105820. |
mutations in the regulatory and coding regions of the bovine npy gene can potentially affect the neuronal regulation of appetite and feeding behaviour in cattle. |
2009-03-23 |
2023-08-12 |
cattle |
| Erika Pétervári, Márta Balaskó, Boglárka Uzsoki, Miklós Székel. Effects of neuropeptide Y antagonists on food intake in rats: differences with cold-adaptation. Peptides. vol 27. issue 1. 2009-03-04. PMID:16040156. |
with cold-adaptation the sensitivity to npy and to its antagonists increases, but the hypothalamic npy loses from its fundamental role in the regulation of food intake, and the hyperphagia seen in cold-adaptation may need some other explanation. |
2009-03-04 |
2023-08-12 |
rat |
| Jinghong Shi, Jianqun Yan, Qi Lei, Junjie Zhao, Ke Chen, Dejun Yang, Xiaolin Zhao, Yuan Zhan. Intragastric administration of evodiamine suppresses NPY and AgRP gene expression in the hypothalamus and decreases food intake in rats. Brain research. vol 1247. 2009-02-19. PMID:18955035. |
intragastric administration of evodiamine suppresses npy and agrp gene expression in the hypothalamus and decreases food intake in rats. |
2009-02-19 |
2023-08-12 |
rat |