| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Prashant Nedungadi, Karen P Brisk. Effects of intracerebroventricular administration of the NPY-Y1 receptor antagonist, 1229U91, on hyperphagic and glycemic responses to acute and chronic intermediate insulin-induced hypoglycemia in female rats. Regulatory peptides. vol 159. issue 1-3. 2010-02-23. PMID:19616044. |
pretreatment with 1229u91 did not modify glucose profiles between +2 and +9 h after multiple dosing with nph, but prevented recovery from hypoglycemia at +12 h. the present results show that central npy y1 receptor antagonism inhibits hypoglycemic hyperphagia, and that this suppressive effect on feeding was of greater duration during recurring hypoglycemia. |
2010-02-23 |
2023-08-12 |
rat |
| T Prashant Nedungadi, Karen P Brisk. Effects of intracerebroventricular administration of the NPY-Y1 receptor antagonist, 1229U91, on hyperphagic and glycemic responses to acute and chronic intermediate insulin-induced hypoglycemia in female rats. Regulatory peptides. vol 159. issue 1-3. 2010-02-23. PMID:19616044. |
the current studies support the view that npy y1 receptors function within central neural pathways that govern feeding and glycemic responses to intermediate-acting insulin, and that y1 receptor-mediated stimulation of food intake may habituate in a positive manner to repetitive insulin-induced hypoglycemia. |
2010-02-23 |
2023-08-12 |
rat |
| Andrea Stofkova, Martin Haluzik, Blanka Zelezna, Alexander Kiss, Martina Skurlova, Zdenka Lacinova, Jana Jurcovicov. Enhanced expressions of mRNA for neuropeptide Y and interleukin 1 beta in hypothalamic arcuate nuclei during adjuvant arthritis-induced anorexia in Lewis rats. Neuroimmunomodulation. vol 16. issue 6. 2010-02-01. PMID:19609086. |
food intake is activated by hypothalamic orexigenic neuropeptide y (npy), which is mainly under the dual control of leptin and ghrelin. |
2010-02-01 |
2023-08-12 |
human |
| Benedek Erdos, Christopher S Broxson, Idan Cudykier, Bilgen Basgut, Melissa Whidden, Tessa Landa, Philip J Scarpace, Nihal Tüme. Effect of high-fat diet feeding on hypothalamic redox signaling and central blood pressure regulation. Hypertension research : official journal of the Japanese Society of Hypertension. vol 32. issue 11. 2010-01-12. PMID:19713964. |
furthermore, we investigated whether hf feeding affects catecholamine and neuropeptide y (npy) biosynthesis in the adrenal medulla. |
2010-01-12 |
2023-08-12 |
rat |
| Dawna Salter-Venzon, Alan G Watt. Site-specific attenuation of food intake but not the latency to eat after hypothalamic injections of neuropeptide Y in dehydrated-anorexic rats. American journal of physiology. Regulatory, integrative and comparative physiology. vol 297. issue 6. 2009-12-11. PMID:19741057. |
furthermore, the onset and size of the strong and rapidly induced compensatory feeding that follows the return of water to de-anorexic animals was also unaffected by any npy injections. |
2009-12-11 |
2023-08-12 |
rat |
| Su-Jin Kim, Sung-Jin Lee, Sanghyun Lee, Sungwook Chae, Man-Deuk Han, Woongchon Mar, Kung-Woo Na. Rutecarpine ameliorates bodyweight gain through the inhibition of orexigenic neuropeptides NPY and AgRP in mice. Biochemical and biophysical research communications. vol 389. issue 3. 2009-11-13. PMID:19732749. |
these results indicate that rutecarpine ameliorates obesity by inhibiting food intake, which involves inhibited expression of the orexigenic neuropeptides npy and agrp. |
2009-11-13 |
2023-08-12 |
mouse |
| Louise E Olofsson, Andrew A Pierce, Allison W X. Functional requirement of AgRP and NPY neurons in ovarian cycle-dependent regulation of food intake. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 37. 2009-11-13. PMID:19805233. |
functional requirement of agrp and npy neurons in ovarian cycle-dependent regulation of food intake. |
2009-11-13 |
2023-08-12 |
mouse |
| Louise E Olofsson, Andrew A Pierce, Allison W X. Functional requirement of AgRP and NPY neurons in ovarian cycle-dependent regulation of food intake. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 37. 2009-11-13. PMID:19805233. |
in this study, we show that changes in hypothalamic expression of agouti-related protein (agrp) and neuropeptide y (npy) coincide with the cyclic changes in feeding across the estrous cycle. |
2009-11-13 |
2023-08-12 |
mouse |
| Louise E Olofsson, Andrew A Pierce, Allison W X. Functional requirement of AgRP and NPY neurons in ovarian cycle-dependent regulation of food intake. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 37. 2009-11-13. PMID:19805233. |
this study indicates that neurons coexpressing agrp and npy are functionally required for the cyclic changes in feeding across estrous cycle and that agrp and npy neurons are essential mediators of estrogen's anorexigenic function. |
2009-11-13 |
2023-08-12 |
mouse |
| Birgitte Tiesjema, Susanne E la Fleur, Mieneke C M Luijendijk, Roger A H Ada. Sustained NPY overexpression in the PVN results in obesity via temporarily increasing food intake. Obesity (Silver Spring, Md.). vol 17. issue 7. 2009-10-08. PMID:19553928. |
sustained npy overexpression in the pvn results in obesity via temporarily increasing food intake. |
2009-10-08 |
2023-08-12 |
rat |
| Birgitte Tiesjema, Susanne E la Fleur, Mieneke C M Luijendijk, Roger A H Ada. Sustained NPY overexpression in the PVN results in obesity via temporarily increasing food intake. Obesity (Silver Spring, Md.). vol 17. issue 7. 2009-10-08. PMID:19553928. |
these data indicate that overexpression of npy in the pvn results in obesity by increasing food intake until a certain body weight is achieved. |
2009-10-08 |
2023-08-12 |
rat |
| Kenneth A Gruber, Wei Fan, Helena Akerberg, Dan Larhammar, Melissa J S Chee, William F Colmers, Roger D Con. Neuropeptide Y and gamma-melanocyte stimulating hormone (gamma-MSH) share a common pressor mechanism of action. Endocrine. vol 35. issue 3. 2009-09-11. PMID:19363600. |
for example, both the melanocortin and neuropeptide y (npy) peptide families, known to regulate food intake, also produce central hypertensive effects. |
2009-09-11 |
2023-08-12 |
Not clear |
| Koji Murashita, Tadahide Kurokawa, Lars O E Ebbesson, Sigurd O Stefansson, Ivar Rønnesta. Characterization, tissue distribution, and regulation of agouti-related protein (AgRP), cocaine- and amphetamine-regulated transcript (CART) and neuropeptide Y (NPY) in Atlantic salmon (Salmo salar). General and comparative endocrinology. vol 162. issue 2. 2009-09-03. PMID:19332070. |
agrp-1 and cart mrna levels in the brain decreased after 6 days of fasting while agrp-2 and npy showed no significant change, suggesting that agrp-1 and cart are involved in feeding regulation in atlantic salmon. |
2009-09-03 |
2023-08-12 |
Not clear |
| A W Ross, C E Johnson, L M Bell, L Reilly, J S Duncan, P Barrett, P D Heideman, P J Morga. Divergent regulation of hypothalamic neuropeptide Y and agouti-related protein by photoperiod in F344 rats with differential food intake and growth. Journal of neuroendocrinology. vol 21. issue 7. 2009-08-31. PMID:19490367. |
potentially, the sd increase in npy expression may inhibit growth by decreasing ghrh and somatostatin expression, whereas the decrease in agrp expression probably leads to reduced food intake. |
2009-08-31 |
2023-08-12 |
rat |
| A W Ross, C E Johnson, L M Bell, L Reilly, J S Duncan, P Barrett, P D Heideman, P J Morga. Divergent regulation of hypothalamic neuropeptide Y and agouti-related protein by photoperiod in F344 rats with differential food intake and growth. Journal of neuroendocrinology. vol 21. issue 7. 2009-08-31. PMID:19490367. |
the present study reveals an atypical and divergent regulation of npy and agrp, which may relate to their separate roles with respect to growth and food intake, respectively. |
2009-08-31 |
2023-08-12 |
rat |
| Sarath Chandra Peddu, Jason P Breves, Hiroyuki Kaiya, E Gordon Grau, Larry G Rile. Pre- and postprandial effects on ghrelin signaling in the brain and on the GH/IGF-I axis in the Mozambique tilapia (Oreochromis mossambicus). General and comparative endocrinology. vol 161. issue 3. 2009-08-25. PMID:19245815. |
tilapia that missed the scheduled feeding exhibited no changes in brain ghs-r1a, grln and npy postprandial mrna levels; whereas ghs-r1b mrna levels were significantly reduced 1 and 3 h postprandially. |
2009-08-25 |
2023-08-12 |
Not clear |
| Erin MacDonald, Hélène Volkof. Cloning, distribution and effects of season and nutritional status on the expression of neuropeptide Y (NPY), cocaine and amphetamine regulated transcript (CART) and cholecystokinin (CCK) in winter flounder (Pseudopleuronectes americanus). Hormones and behavior. vol 56. issue 1. 2009-08-21. PMID:19303880. |
our results suggest that npy and cck, but maybe not cart, might have a major role in the regulation of feeding in winter flounder and might contribute to the seasonal fluctuations in appetite in this species. |
2009-08-21 |
2023-08-12 |
Not clear |
| Kenji Kojima, Motoki Kamijo, Haruaki Kageyama, Minoru Uchiyama, Seiji Shioda, Kouhei Matsud. Neuronal relationship between orexin-A- and neuropeptide Y-induced orexigenic actions in goldfish. Neuropeptides. vol 43. issue 2. 2009-08-19. PMID:19261328. |
the stimulatory effect of intracerebroventricular injection of npy at 1 pmol/g body weight (bw) on food intake was abolished by treatment with the orexin receptor-1 antagonist, sb334867, at 10 pmol/g bw whereas the npy y1-receptor antagonist, bibp3226, at 100 pmol/g bw attenuated orexin-a (at 2.8 pmol/g bw)-stimulated feeding. |
2009-08-19 |
2023-08-12 |
Not clear |
| Tia Maric, Anna Cantor, Holly Cuccioletta, Stephanie Tobin, Uri Shale. Neuropeptide Y augments cocaine self-administration and cocaine-induced hyperlocomotion in rats. Peptides. vol 30. issue 4. 2009-08-05. PMID:19063928. |
central administration of npy induces feeding in sated animals, and importantly, is reported to increase the rewarding properties of food. |
2009-08-05 |
2023-08-12 |
rat |
| Kouhei Matsuda, Kenji Kojima, Sei-Ichi Shimakura, Tohru Miura, Minoru Uchiyama, Seiji Shioda, Hironori Ando, Akiyoshi Takahash. Relationship between melanin-concentrating hormone- and neuropeptide Y-containing neurons in the goldfish hypothalamus. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 153. issue 1. 2009-07-17. PMID:18950727. |
intracerebroventricular (icv) administration of melanin-concentrating hormone (mch) inhibits food intake in goldfish, unlike the orexigenic action in rodents, via the melanocortin system with suppression of neuropeptide y (npy) mrna expression. |
2009-07-17 |
2023-08-12 |
Not clear |