| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J-Y Sun, M-Y Jing, J-F Wang, X-Y Wen. The approach to the mechanism of calcitonin gene-related peptide-inducing inhibition of food intake. Journal of animal physiology and animal nutrition. vol 94. issue 5. 2011-03-02. PMID:19906139. |
npy and mch) expression, and ultimately suppressed food intake that was functionally coupled to camp/pka pathway activation. |
2011-03-02 |
2023-08-12 |
rat |
| L Zhang, N J Lee, A D Nguyen, R F Enriquez, S J Riepler, B Stehrer, E Yulyaningsih, S Lin, Y C Shi, P A Baldock, H Herzog, A Sainsbur. Additive actions of the cannabinoid and neuropeptide Y systems on adiposity and lipid oxidation. Diabetes, obesity & metabolism. vol 12. issue 7. 2011-02-24. PMID:20590734. |
cannabinoids, acting via the cannabinoid-1 (cb1) receptor, and neuropeptide y (npy) are important modulators of feeding behaviour, energy metabolism and body composition. |
2011-02-24 |
2023-08-12 |
Not clear |
| Marta Conde-Sieira, Maria J Agulleiro, Ariel J Aguilar, Jesús M Míguez, José M Cerdá-Reverter, José L Soenga. Effect of different glycaemic conditions on gene expression of neuropeptides involved in control of food intake in rainbow trout; interaction with stress. The Journal of experimental biology. vol 213. issue Pt 22. 2011-02-24. PMID:21037065. |
to assess mechanisms relating to food intake and glucosensing in fish, and their interaction with stress, we evaluated changes in the expression of orexigenic (npy) and anorexigenic (pomc, cart and crf) peptides in central glucosensing areas (hypothalamus and hindbrain) of rainbow trout subjected to normoglycaemic (control), hypoglycaemic (4 mg insulin kg(-1)) or hyperglycaemic (500 mg glucose kg(-1)) conditions for 6 h under normal stocking density (nsd; 10 kg fish mass m(-3)) or under stress conditions induced by high stocking density (hsd; 70 kg fish mass m(-3)). |
2011-02-24 |
2023-08-12 |
Not clear |
| Michelle Pelling, Neal Anthwal, David McNay, Gerard Gradwohl, Andrew B Leiter, Francois Guillemot, Siew-Lan An. Differential requirements for neurogenin 3 in the development of POMC and NPY neurons in the hypothalamus. Developmental biology. vol 349. issue 2. 2011-02-24. PMID:21074524. |
given the opposing roles of pomc and npy neurons in regulating food intake, these results indicate that ngn3 plays a central role in the generation of neuronal populations controlling energy homeostasis in mice. |
2011-02-24 |
2023-08-12 |
mouse |
| L V K S Bhaskar, K Thangaraj, G Pardhasaradhi, K P Kumar, L Singh, V R Ra. Neuropeptide Y gene polymorphisms are not associated with obesity in a South Indian population. European journal of clinical nutrition. vol 64. issue 8. 2011-02-10. PMID:20531438. |
among the primary functions associated with npy are its acute effects on feeding behavior and energy expenditure. |
2011-02-10 |
2023-08-12 |
Not clear |
| Angela M Lyons, Todd E Thiel. Neuropeptide Y conjugated to saporin alters anxiety-like behavior when injected into the central nucleus of the amygdala or basomedial hypothalamus in BALB/cJ mice. Peptides. vol 31. issue 12. 2011-02-10. PMID:20863864. |
recently, the neurotoxin saporin, when conjugated to npy (npy-sap), was shown to selectively kill npy receptor-expressing neurons and has been used as a tool to study the central npy neurocircuitry involved with feeding behaviors. |
2011-02-10 |
2023-08-12 |
mouse |
| Shaun P Brothers, Claes Wahlested. Therapeutic potential of neuropeptide Y (NPY) receptor ligands. EMBO molecular medicine. vol 2. issue 11. 2011-02-09. PMID:20972986. |
since its discovery, npy has been implicated in metabolic regulation and, although interest in its role in central mechanisms related to food intake and obesity has somewhat diminished, the topic remains a strong focus of research concerning npy signalling. |
2011-02-09 |
2023-08-12 |
human |
| M W A de Backer, M A D Brans, A J van Rozen, E M van der Zwaal, M C M Luijendijk, K G Garner, M de Krom, O van Beekum, S E la Fleur, R A H Ada. Suppressor of cytokine signaling 3 knockdown in the mediobasal hypothalamus: counterintuitive effects on energy balance. Journal of molecular endocrinology. vol 45. issue 5. 2011-02-02. PMID:20819948. |
since leptin is known to stimulate npy transcription in the absence of socs3, these data suggest that knockdown of socs3 mrna limited to the mbh increases npy mrna levels, which subsequently decreases locomotor activity and alters feeding patterns. |
2011-02-02 |
2023-08-12 |
mouse |
| Andrea Stofkova, Blanka Zelezna, Marianna Romzova, Olga Ulicna, Alexander Kiss, Martina Skurlova, Jana Jurcovicov. Effect of feeding status on adjuvant arthritis severity, cachexia, and insulin sensitivity in male Lewis rats. Mediators of inflammation. vol 2010. 2011-02-02. PMID:20953376. |
independently of feeding status, aa induced cachexia, in which modulation of mrna expressions for appetite-regulating neuropeptides (npy, agrp, pomc, cart) in the arcuate nucleus (arc) does not play a primary role. |
2011-02-02 |
2023-08-12 |
rat |
| Sean P Bradley, Lucia M Pattullo, Priyesh N Patel, Brian J Prendergas. Photoperiodic regulation of the orexigenic effects of ghrelin in Siberian hamsters. Hormones and behavior. vol 58. issue 4. 2011-01-24. PMID:20600050. |
the data also identify photoperiod-induced changes in the ability of ghrelin to activate arc npy neurons as a possible mechanism by which changes in day length alter food intake. |
2011-01-24 |
2023-08-12 |
Not clear |
| Vinicius F Campos, Tiago Collares, João C Deschamps, Fabiana K Seixas, Odir A Dellagostin, Carlos Frederico C Lanes, Juliana Sandrini, Luis Fernando Marins, Marcelo Okamoto, Luís A Sampaio, Ricardo B Robald. Identification, tissue distribution and evaluation of brain neuropeptide Y gene expression in the Brazilian flounder Paralichthys orbignyanus. Journal of biosciences. vol 35. issue 3. 2011-01-14. PMID:20826950. |
neuropeptide y (npy) is one of the most potent stimulants of food intake in vertebrates, mammals and fish. |
2011-01-14 |
2023-08-12 |
Not clear |
| Vinicius F Campos, Tiago Collares, João C Deschamps, Fabiana K Seixas, Odir A Dellagostin, Carlos Frederico C Lanes, Juliana Sandrini, Luis Fernando Marins, Marcelo Okamoto, Luís A Sampaio, Ricardo B Robald. Identification, tissue distribution and evaluation of brain neuropeptide Y gene expression in the Brazilian flounder Paralichthys orbignyanus. Journal of biosciences. vol 35. issue 3. 2011-01-14. PMID:20826950. |
the objectives of this study were to clone npy cdna, evaluate the mrna levels in different tissues of flounder, and also evaluate brain npy expression to associate food intake with npy expression levels. |
2011-01-14 |
2023-08-12 |
Not clear |
| Vinicius F Campos, Tiago Collares, João C Deschamps, Fabiana K Seixas, Odir A Dellagostin, Carlos Frederico C Lanes, Juliana Sandrini, Luis Fernando Marins, Marcelo Okamoto, Luís A Sampaio, Ricardo B Robald. Identification, tissue distribution and evaluation of brain neuropeptide Y gene expression in the Brazilian flounder Paralichthys orbignyanus. Journal of biosciences. vol 35. issue 3. 2011-01-14. PMID:20826950. |
no significant differences were observed in brain npy gene expression over 24 h after food intake at a temperature of 15 +or- 3 degrees c. no correlation was observed among plasma glucose, total protein, cholesterol, triglycerides and npy expression levels during this 24 h period. |
2011-01-14 |
2023-08-12 |
Not clear |
| Xiaomeng Pei, Hua A. [Relationship between ghrelin and food intake or obesity]. Wei sheng yan jiu = Journal of hygiene research. vol 36. issue 1. 2010-12-10. PMID:17424866. |
ghrelin stimulates food intake and regulates energy homeostasis through activating the expression of the orexigenic neuropeptides npy (neuropeptide y)/agrp (agouti-related protein) in hypothalamic neurons, by which it plays a key role in obesity pathogenesis. |
2010-12-10 |
2023-08-12 |
Not clear |
| Megan J Dailey, Timothy J Bartnes. Arcuate nucleus destruction does not block food deprivation-induced increases in food foraging and hoarding. Brain research. vol 1323. 2010-11-22. PMID:20138163. |
neuropeptide y (npy) and agouti-related protein (agrp), two orexigenic neuropeptides known to stimulate food intake in a variety of species, applied centrally to siberian hamsters increases foraging and especially hoarding with lesser increases in food intake. |
2010-11-22 |
2023-08-12 |
Not clear |
| Pallab K Gangul. Neuropeptide Y level in paraventricular nucleus of experimental diabetic rats: correlation with sympathetic activity and body weight. International journal of general medicine. vol 3. 2010-11-15. PMID:21042571. |
neuropeptide y (npy), colocalized with norepinephrine neuron, is known to modulate sympathetic activity and feeding behavior. |
2010-11-15 |
2023-08-12 |
rat |
| Pallab K Gangul. Neuropeptide Y level in paraventricular nucleus of experimental diabetic rats: correlation with sympathetic activity and body weight. International journal of general medicine. vol 3. 2010-11-15. PMID:21042571. |
while npy level was increased immediately within 2 weeks (along with feeding behavior), norepinephrine level was increased only after 8 weeks following injection of streptozotocin. |
2010-11-15 |
2023-08-12 |
rat |
| Pallab K Gangul. Neuropeptide Y level in paraventricular nucleus of experimental diabetic rats: correlation with sympathetic activity and body weight. International journal of general medicine. vol 3. 2010-11-15. PMID:21042571. |
these results are interpreted to mean that a strong correlation exists between the feeding behavior and npy level in pvn. |
2010-11-15 |
2023-08-12 |
rat |
| Pallab K Gangul. Neuropeptide Y level in paraventricular nucleus of experimental diabetic rats: correlation with sympathetic activity and body weight. International journal of general medicine. vol 3. 2010-11-15. PMID:21042571. |
in addition, controversy exists regarding pleiotropic activities of npy related to the feeding behavior of these animals. |
2010-11-15 |
2023-08-12 |
rat |
| Szilamér Ferenczi, Cristina Núñez, Bernadett Pintér-Kübler, Anna Földes, Fátima Martín, Vera Ladnyánszky Márkus, M Victoria Milanés, Krisztina J Kovác. Changes in metabolic-related variables during chronic morphine treatment. Neurochemistry international. vol 57. issue 3. 2010-11-04. PMID:20600437. |
the disregulated feeding pattern was not reflected in changes of orexin transcription, however, a compensatory upregulation was revealed in hypothalamic npy expression. |
2010-11-04 |
2023-08-12 |
rat |