| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rebecca E Mercer, Melissa J S Chee, William F Colmer. The role of NPY in hypothalamic mediated food intake. Frontiers in neuroendocrinology. vol 32. issue 4. 2012-01-23. PMID:21726573. |
the role of npy in hypothalamic mediated food intake. |
2012-01-23 |
2023-08-12 |
human |
| Luigi Brunetti, Chiara Di Nisio, Lucia Recinella, Annalisa Chiavaroli, Sheila Leone, Claudio Ferrante, Giustino Orlando, Michele Vacc. Effects of vaspin, chemerin and omentin-1 on feeding behavior and hypothalamic peptide gene expression in the rat. Peptides. vol 32. issue 9. 2012-01-12. PMID:21855588. |
therefore, vaspin is an adipokine triggering anorectic pathways in the hypothalamus, where reduction of npy and increase of pomc mrna levels mediate feeding inhibition. |
2012-01-12 |
2023-08-12 |
mouse |
| M F Wiater, S Mukherjee, A-J Li, T T Dinh, E M Rooney, S M Simasko, S Ritte. Circadian integration of sleep-wake and feeding requires NPY receptor-expressing neurons in the mediobasal hypothalamus. American journal of physiology. Regulatory, integrative and comparative physiology. vol 301. issue 5. 2011-12-22. PMID:21880863. |
circadian integration of sleep-wake and feeding requires npy receptor-expressing neurons in the mediobasal hypothalamus. |
2011-12-22 |
2023-08-12 |
rat |
| Annabelle Reaux-Le Goazigo, Laurence Bodineau, Nadia De Mota, Lydie Jeandel, Nicolas Chartrel, Claude Knauf, Carine Raad, Philippe Valet, Catherine Llorens-Corte. Apelin and the proopiomelanocortin system: a new regulatory pathway of hypothalamic α-MSH release. American journal of physiology. Endocrinology and metabolism. vol 301. issue 5. 2011-12-20. PMID:21846903. |
in the arc, neuropeptide y (npy)-producing neurons stimulate food intake, whereas neurons releasing the proopiomelanocortin (pomc)-derived peptide α-melanocyte-stimulating hormone (α-msh) strongly decrease food intake. |
2011-12-20 |
2023-08-12 |
mouse |
| Wagner L Prado, Lila M Oyama, Mara C Lofrano-Prado, Aline de Piano, Sérgio G Stella, Cláudia M O Nascimento, June Carnier, Danielle A Caranti, Lian Tock, Sérgio Tufik, Marco Túlio de Mello, Ana R Dâmas. Alterations in downstream mediators involved in central control of eating behavior in obese adolescents submitted to a multidisciplinary therapy. The Journal of adolescent health : official publication of the Society for Adolescent Medicine. vol 49. issue 3. 2011-12-20. PMID:21856523. |
the aim of this study was to verify the effects of a multidisciplinary therapy (24 weeks) on neurohormonal control of food intake, specifically in orexigenic (total ghrelin, agouti-related protein [agrp], neuropeptide y [npy], and melanin-concentrating hormone) and anorexigenic factors (leptin, insulin, and alpha-melanocyte stimulating hormone [α-msh]), in obese adolescents. |
2011-12-20 |
2023-08-12 |
Not clear |
| R M Señarís, M L Trujillo, B Navia, G Comes, B Ferrer, M Giralt, J Hidalg. Interleukin-6 regulates the expression of hypothalamic neuropeptides involved in body weight in a gender-dependent way. Journal of neuroendocrinology. vol 23. issue 8. 2011-12-12. PMID:21564350. |
neuropeptide y (npy), agouti-related peptide (agrp), melanin-concentrating hormone (mch), prepro-orexin (preproox) (orexigenic and anabolic neuropeptides), pro-opiomelanocortin (pomc) and corticotrophin-releasing hormone (crh) (anorexigenic and catabolic peptides) mrna levels were determined using in situ hybridisation in young (2-4 month-old) and old (10-12 month-old) female and male mice under different feeding conditions: normal diet (control) and high-fat diet (hfd), and 24 h-food deprivation. |
2011-12-12 |
2023-08-12 |
mouse |
| Natalie L Trent, Janet L Menar. Infusions of neuropeptide Y into the lateral septum reduce anxiety-related behaviors in the rat. Pharmacology, biochemistry, and behavior. vol 99. issue 4. 2011-12-09. PMID:21693128. |
in experiment 1, the effects of infusions of npy (1.5 μg) into the lateral septum were investigated in three animal models of anxiety: the elevated plus-maze, novelty-induced suppression of feeding, and shock-probe burying tests. |
2011-12-09 |
2023-08-12 |
rat |
| Natalie L Trent, Janet L Menar. Infusions of neuropeptide Y into the lateral septum reduce anxiety-related behaviors in the rat. Pharmacology, biochemistry, and behavior. vol 99. issue 4. 2011-12-09. PMID:21693128. |
in the novelty-induced suppression of feeding test, rats infused with npy showed decreases in the latency to consume a palatable snack in a novel (but not familiar) environment, suggesting a reduction in anxiety independent of increases in appetite. |
2011-12-09 |
2023-08-12 |
rat |
| Natalie L Trent, Janet L Menar. Infusions of neuropeptide Y into the lateral septum reduce anxiety-related behaviors in the rat. Pharmacology, biochemistry, and behavior. vol 99. issue 4. 2011-12-09. PMID:21693128. |
it is concluded that npy produces anxiolytic-like actions in the lateral septum in two animal models of anxiety: the novelty-induced suppression of feeding, and shock-probe burying tests, and that this anxiolysis is dependent on y1 receptor activation in the feeding test. |
2011-12-09 |
2023-08-12 |
rat |
| Lígia Sousa-Ferreira, Manuel Garrido, Isabel Nascimento-Ferreira, Clévio Nobrega, Ana Santos-Carvalho, Ana Rita Alvaro, Joana Rosmaninho-Salgado, Manuella Kaster, Sebastian Kügler, Luís Pereira de Almeida, Claudia Cavada. Moderate long-term modulation of neuropeptide Y in hypothalamic arcuate nucleus induces energy balance alterations in adult rats. PloS one. vol 6. issue 7. 2011-12-06. PMID:21799827. |
in addition, moderate down-regulation of npy did not affect basal feeding or normal body weight gain but the response to food deprivation was compromised since fasting-induced hyperphagia was inhibited and fasting-induced decrease in locomotor activity was absent.these results highlight the importance of the physiological arc npy levels oscillations on feeding regulation, fasting response and body weight preservation, and are important for the design of therapeutic interventions for obesity that include the npy. |
2011-12-06 |
2023-08-12 |
rat |
| Young Wha Moon, Si Ho Choi, Sang Bae Yoo, Jong-Ho Lee, Jeong Won Jahn. 5-hydroxy-L-tryptophan Suppressed Food Intake in Rats Despite an Increase in the Arcuate NPY Expression. Experimental neurobiology. vol 19. issue 3. 2011-11-23. PMID:22110352. |
5-hydroxy-l-tryptophan suppressed food intake in rats despite an increase in the arcuate npy expression. |
2011-11-23 |
2023-08-12 |
rat |
| Sabrina Diano, Zhong-Wu Liu, Jin Kwon Jeong, Marcelo O Dietrich, Hai-Bin Ruan, Esther Kim, Shigetomo Suyama, Kaitlin Kelly, Erika Gyengesi, Jack L Arbiser, Denise D Belsham, David A Sarruf, Michael W Schwartz, Anton M Bennett, Marya Shanabrough, Charles V Mobbs, Xiaoyong Yang, Xiao-Bing Gao, Tamas L Horvat. Peroxisome proliferation-associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity. Nature medicine. vol 17. issue 9. 2011-11-18. PMID:21873987. |
here we show that suppression of ros diminishes pro-opiomelanocortin (pomc) cell activation and promotes the activity of neuropeptide y (npy)- and agouti-related peptide (agrp)-co-producing (npy/agrp) neurons and feeding, whereas ros-activates pomc neurons and reduces feeding. |
2011-11-18 |
2023-08-12 |
mouse |
| Aifen Yan, Lingjuang Zhang, Zhiguo Tang, Yanhong Zhang, Chaobin Qin, Bo Li, Wensheng Li, Haoran Li. Orange-spotted grouper (Epinephelus coioides) orexin: molecular cloning, tissue expression, ontogeny, daily rhythm and regulation of NPY gene expression. Peptides. vol 32. issue 7. 2011-11-07. PMID:21600944. |
our results imply that orexin may be involved in feeding in the orange-spotted grouper and orexin-a is a stimulator of npy mrna expression in vivo and in vitro. |
2011-11-07 |
2023-08-12 |
Not clear |
| Daisuke Kohno, Hideyuki Sone, Shigeyasu Tanaka, Hideharu Kurita, Darambazar Gantulga, Toshihiko Yad. AMP-activated protein kinase activates neuropeptide Y neurons in the hypothalamic arcuate nucleus to increase food intake in rats. Neuroscience letters. vol 499. issue 3. 2011-11-07. PMID:21658429. |
intracerebroventricular administration of aicar increased food intake, and the aicar-induced food intake was abolished by the co-administration of npy y1 receptor antagonist, 1229u91. |
2011-11-07 |
2023-08-12 |
rat |
| Daisuke Kohno, Hideyuki Sone, Shigeyasu Tanaka, Hideharu Kurita, Darambazar Gantulga, Toshihiko Yad. AMP-activated protein kinase activates neuropeptide Y neurons in the hypothalamic arcuate nucleus to increase food intake in rats. Neuroscience letters. vol 499. issue 3. 2011-11-07. PMID:21658429. |
these results indicate that the activation of ampk leads to the activation of arc npy neurons through ca(2+) influx, thereby causing npy-dependent food intake. |
2011-11-07 |
2023-08-12 |
rat |
| Jill S Carmody, Phyllis Wan, Domenico Accili, Lori M Zeltser, Rudolph L Leibe. Respective contributions of maternal insulin resistance and diet to metabolic and hypothalamic phenotypes of progeny. Obesity (Silver Spring, Md.). vol 19. issue 3. 2011-10-04. PMID:20948526. |
quantification of proopiomelanocortin (pomc) and neuropeptide-y (npy) populations in the arcuate nucleus of the hypothalamus (arh) of offspring of wild-type vs. insr(+/-) dams was performed to determine whether maternal ir affects the formation of central feeding circuits. |
2011-10-04 |
2023-08-12 |
mouse |
| Jian-Guo Cui, Gang-Bing Tang, De-Hua Wan. Hypothalamic neuropeptides, not leptin sensitivity, contributes to the hyperphagia in lactating Brandt's voles, Lasiopodomys brandtii. The Journal of experimental biology. vol 214. issue Pt 13. 2011-10-03. PMID:21653818. |
food intake was positively correlated with npy and agrp mrna expression but negatively correlated with pomc mrna expression during lactation. |
2011-10-03 |
2023-08-12 |
Not clear |
| Jian-Guo Cui, Gang-Bing Tang, De-Hua Wan. Hypothalamic neuropeptides, not leptin sensitivity, contributes to the hyperphagia in lactating Brandt's voles, Lasiopodomys brandtii. The Journal of experimental biology. vol 214. issue Pt 13. 2011-10-03. PMID:21653818. |
these data suggest that hyperphagia during lactation was associated with low leptin levels, but not impaired leptin sensitivity, and that the hypothalamic neuropeptides npy, agrp and pomc are involved in mediating the role of leptin in food intake regulation in lactating brandt's voles. |
2011-10-03 |
2023-08-12 |
Not clear |
| R Valen, A-E O Jordal, K Murashita, I Rønnesta. Postprandial effects on appetite-related neuropeptide expression in the brain of Atlantic salmon, Salmo salar. General and comparative endocrinology. vol 171. issue 3. 2011-09-23. PMID:21377470. |
following feeding of a single meal to atlantic salmon, the temporal changes in the brain mrna expression of neuropeptide y (npy), cocaine-amphetamine regulated transcript (cart), peptide yy (pyy), two isoforms of agouti-related protein (agrp), two isoforms of cholecystokinin (cck), and four isoforms of proopiomelanocortin (pomc) were assessed by q-pcr. |
2011-09-23 |
2023-08-12 |
Not clear |
| R Valen, A-E O Jordal, K Murashita, I Rønnesta. Postprandial effects on appetite-related neuropeptide expression in the brain of Atlantic salmon, Salmo salar. General and comparative endocrinology. vol 171. issue 3. 2011-09-23. PMID:21377470. |
on the other hand, the npy and agrp isoforms which have been described as playing orexigenic roles in mammals, showed an opposite response in salmon and both were elevated in the first 3h after feeding. |
2011-09-23 |
2023-08-12 |
Not clear |