| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dong-Yih Kuo, Pei-Ni Chen, Meng-Hsien Kuo, Chin-Hsiu Chen, Yih-Shou Hsieh, Shu-Chen Ch. NF-κB knockdown can modulate amphetamine-mediated feeding response. Neuropharmacology. vol 62. issue 4. 2012-07-27. PMID:22182781. |
the npy gene was down-regulated with maximal response on day 2 during amph treatment, which was consistent with the response to feeding behavior. |
2012-07-27 |
2023-08-12 |
rat |
| Dong-Yih Kuo, Pei-Ni Chen, Shu-Chen Chu, Yih-Shou Hsie. Knocking down the transcript of NF-kappaB modulates the reciprocal regulation of endogenous antioxidants and feeding behavior in phenylpropanolamine-treated rats. Archives of toxicology. vol 86. issue 3. 2012-07-17. PMID:21989786. |
it has been reported that oxidative stress, antioxidants, and neuropeptide y (npy) are involved in regulating the feeding behavior of phenylpropanolamine (ppa), a sympathomimetic drug. |
2012-07-17 |
2023-08-12 |
rat |
| Dong-Yih Kuo, Pei-Ni Chen, Shu-Chen Chu, Yih-Shou Hsie. Knocking down the transcript of NF-kappaB modulates the reciprocal regulation of endogenous antioxidants and feeding behavior in phenylpropanolamine-treated rats. Archives of toxicology. vol 86. issue 3. 2012-07-17. PMID:21989786. |
results showed that nf-κb, sod, and gpx increased, with a maximal response on day 2, while the food intake and npy decreased with the biggest reduction on day 2 during ppa treatment. |
2012-07-17 |
2023-08-12 |
rat |
| E Yokobori, M Azuma, R Nishiguchi, K S Kang, M Kamijo, M Uchiyama, K Matsud. Neuropeptide Y stimulates food intake in the Zebrafish, Danio rerio. Journal of neuroendocrinology. vol 24. issue 5. 2012-07-09. PMID:22250860. |
neuropeptide y (npy) is a potent orexigenic neuropeptide implicated in feeding regulation in mammals. |
2012-07-09 |
2023-08-12 |
zebrafish |
| E Yokobori, M Azuma, R Nishiguchi, K S Kang, M Kamijo, M Uchiyama, K Matsud. Neuropeptide Y stimulates food intake in the Zebrafish, Danio rerio. Journal of neuroendocrinology. vol 24. issue 5. 2012-07-09. PMID:22250860. |
however, except for the case of the goldfish, the involvement of npy in the feeding behaviour of teleost fish has not well been studied. |
2012-07-09 |
2023-08-12 |
zebrafish |
| E Yokobori, M Azuma, R Nishiguchi, K S Kang, M Kamijo, M Uchiyama, K Matsud. Neuropeptide Y stimulates food intake in the Zebrafish, Danio rerio. Journal of neuroendocrinology. vol 24. issue 5. 2012-07-09. PMID:22250860. |
therefore, we investigated the role of npy in food intake using a zebrafish (danio rerio) model because the molecular bases of npy and its receptor have been well studied in this species. |
2012-07-09 |
2023-08-12 |
zebrafish |
| E Yokobori, M Azuma, R Nishiguchi, K S Kang, M Kamijo, M Uchiyama, K Matsud. Neuropeptide Y stimulates food intake in the Zebrafish, Danio rerio. Journal of neuroendocrinology. vol 24. issue 5. 2012-07-09. PMID:22250860. |
we examined the effect of feeding status on npy-like immunoreactivity and the expression level of the npy transcript in the brain. |
2012-07-09 |
2023-08-12 |
zebrafish |
| E Yokobori, M Azuma, R Nishiguchi, K S Kang, M Kamijo, M Uchiyama, K Matsud. Neuropeptide Y stimulates food intake in the Zebrafish, Danio rerio. Journal of neuroendocrinology. vol 24. issue 5. 2012-07-09. PMID:22250860. |
administration of npy on food intake. |
2012-07-09 |
2023-08-12 |
zebrafish |
| Sara L Hargrave, Kimberly P Kinzi. Repeated gastric distension alters food intake and neuroendocrine profiles in rats. Physiology & behavior. vol 105. issue 4. 2012-05-24. PMID:22115950. |
despite equivalent body weights and daily caloric consumption, rgd animals had significantly decreased leptin levels (p<0.05), and tended to have increased fasting arcuate npy levels (p=0.08), which were suppressed more than control animals following food intake (control and rgd decreases from baseline were 184.95% and 257.42%, respectively). |
2012-05-24 |
2023-08-12 |
rat |
| A Mitra, C M Kotz, E M Kim, M K Grace, M A Kuskowski, C J Billington, A S Levin. Effects of butorphanol on feeding and neuropeptide Y in the rat. Pharmacology, biochemistry, and behavior. vol 100. issue 3. 2012-05-04. PMID:21925202. |
this is consistent with npy's role in normal feeding. |
2012-05-04 |
2023-08-12 |
rat |
| Adam P Chambers, Stephen C Wood. The role of neuropeptide Y in energy homeostasis. Handbook of experimental pharmacology. issue 209. 2012-04-25. PMID:22249809. |
when administered into the brain, npy acts at y1 and y5 receptors to increase food intake. |
2012-04-25 |
2023-08-12 |
Not clear |
| P J Verhulst, S Janssen, J Tack, I Depoorter. Role of the AMP-activated protein kinase (AMPK) signaling pathway in the orexigenic effects of endogenous ghrelin. Regulatory peptides. vol 173. issue 1-3. 2012-04-19. PMID:21963822. |
ghrelin, released from the stomach, stimulates food intake through activation of the ghrelin receptor (ghs-r) located on neuropeptide y (npy)/agouti-related peptide (agrp) neurons in the hypothalamus. |
2012-04-19 |
2023-08-12 |
mouse |
| Zane B Andrew. Central mechanisms involved in the orexigenic actions of ghrelin. Peptides. vol 32. issue 11. 2012-04-16. PMID:21619904. |
in particular, ghrelin does not activate npy neurons in diet-induced obese mice and ghrelin does not increase food intake. |
2012-04-16 |
2023-08-12 |
mouse |
| Karolina P Skibicka, Rozita H Shirazi, Caroline Hansson, Suzanne L Dickso. Ghrelin interacts with neuropeptide Y Y1 and opioid receptors to increase food reward. Endocrinology. vol 153. issue 3. 2012-04-16. PMID:22210742. |
npy mediates the effect of ghrelin on food intake via activation of npy-y1 receptor (npy-y1r); their connection with respect to motivated behavior is unexplored. |
2012-04-16 |
2023-08-12 |
rat |
| Karolina P Skibicka, Rozita H Shirazi, Caroline Hansson, Suzanne L Dickso. Ghrelin interacts with neuropeptide Y Y1 and opioid receptors to increase food reward. Endocrinology. vol 153. issue 3. 2012-04-16. PMID:22210742. |
thus, we identify central npy and opioid signaling as the necessary mediators of food intake and reward effects of ghrelin and localize these interactions to the mesolimbic vta. |
2012-04-16 |
2023-08-12 |
rat |
| Tadashi Yoshida, Laura Semprun-Prieto, Richard D Wainford, Sergiy Sukhanov, Daniel R Kapusta, Patrice Delafontain. Angiotensin II reduces food intake by altering orexigenic neuropeptide expression in the mouse hypothalamus. Endocrinology. vol 153. issue 3. 2012-04-16. PMID:22234465. |
systemic ang ii (1 μg/kg · min) infusion in fvb mice rapidly reduced hypothalamic expression of neuropeptide y (npy) and orexin and decreased food intake at 6 h compared with sham-infused controls but did not change peripheral leptin, ghrelin, adiponectin, glucagon-like peptide, peptide yy, or cholecystokinin levels. |
2012-04-16 |
2023-08-12 |
mouse |
| Tadashi Yoshida, Laura Semprun-Prieto, Richard D Wainford, Sergiy Sukhanov, Daniel R Kapusta, Patrice Delafontain. Angiotensin II reduces food intake by altering orexigenic neuropeptide expression in the mouse hypothalamus. Endocrinology. vol 153. issue 3. 2012-04-16. PMID:22234465. |
intracerebroventricular ang ii infusion (50 ng/kg · min) caused a reduction of food intake, and ang ii dose dependently reduced npy and orexin expression in the hypothalamus cultured ex vivo. |
2012-04-16 |
2023-08-12 |
mouse |
| Tadashi Yoshida, Laura Semprun-Prieto, Richard D Wainford, Sergiy Sukhanov, Daniel R Kapusta, Patrice Delafontain. Angiotensin II reduces food intake by altering orexigenic neuropeptide expression in the mouse hypothalamus. Endocrinology. vol 153. issue 3. 2012-04-16. PMID:22234465. |
thus, ang ii type 1a receptor-dependent ang ii signaling reduces food intake by suppressing the hypothalamic expression of npy and orexin, likely via ampk dephosphorylation. |
2012-04-16 |
2023-08-12 |
mouse |
| Yuko Maejima, Daisuke Kohno, Yusaku Iwasaki, Toshihiko Yad. Insulin suppresses ghrelin-induced calcium signaling in neuropeptide Y neurons of the hypothalamic arcuate nucleus. Aging. vol 3. issue 11. 2012-04-02. PMID:22081645. |
neuropeptide y (npy) neurons in the hypothalamic arcuate nucleus (arc) play an important role in feeding regulation. |
2012-04-02 |
2023-08-12 |
rat |
| Yuko Maejima, Daisuke Kohno, Yusaku Iwasaki, Toshihiko Yad. Insulin suppresses ghrelin-induced calcium signaling in neuropeptide Y neurons of the hypothalamic arcuate nucleus. Aging. vol 3. issue 11. 2012-04-02. PMID:22081645. |
our results suggest that postprandial increase in plasma insulin/ghrelin ratio and insulin inhibition of ghrelin action on arc npy neurons cooperate to effectively inhibit the neuron activity and terminate feeding. |
2012-04-02 |
2023-08-12 |
rat |