| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Lin, D R Gehlert, D A York, G A Bra. Effect of enterostatin on the feeding responses to galanin and NPY. Obesity research. vol 1. issue 3. 2006-02-06. PMID:16353353. |
npy and galanin induced feeding responses in satiated rats. |
2006-02-06 |
2023-08-12 |
rat |
| Michael Koban, Wei Wei Le, Gloria E Hoffma. Changes in hypothalamic corticotropin-releasing hormone, neuropeptide Y, and proopiomelanocortin gene expression during chronic rapid eye movement sleep deprivation of rats. Endocrinology. vol 147. issue 1. 2006-02-03. PMID:16210372. |
consistent with changes in food intake patterns, npy expression rapidly increased in the hypothalamic arcuate nucleus by d 5 of rem-sd, peaking at d 20; by contrast, pomc expression decreased progressively during rem-sd. |
2006-02-03 |
2023-08-12 |
rat |
| Michael Koban, Wei Wei Le, Gloria E Hoffma. Changes in hypothalamic corticotropin-releasing hormone, neuropeptide Y, and proopiomelanocortin gene expression during chronic rapid eye movement sleep deprivation of rats. Endocrinology. vol 147. issue 1. 2006-02-03. PMID:16210372. |
furthermore, changes in npy and pomc agree with current models of food intake behavior, but they are opposite to their acute effects on peripheral energy metabolism and thermogenesis. |
2006-02-03 |
2023-08-12 |
rat |
| Linda Ste Marie, Serge Luquet, Toby B Cole, Richard D Palmite. Modulation of neuropeptide Y expression in adult mice does not affect feeding. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 51. 2006-01-31. PMID:16339312. |
these conflicting observations suggest that chronic lack of npy during development may lead to compensatory changes that normalize regulation of food intake and energy expenditure in the absence of npy. |
2006-01-31 |
2023-08-12 |
mouse |
| Linda Ste Marie, Serge Luquet, Toby B Cole, Richard D Palmite. Modulation of neuropeptide Y expression in adult mice does not affect feeding. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 51. 2006-01-31. PMID:16339312. |
mice chronically overexpressing npy had normal body weight, and administration of dox to these mice did not suppress feeding. |
2006-01-31 |
2023-08-12 |
mouse |
| Claudio Acuna-Goycolea, Anthony N van den Po. Peptide YY(3-36) inhibits both anorexigenic proopiomelanocortin and orexigenic neuropeptide Y neurons: implications for hypothalamic regulation of energy homeostasis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 45. 2006-01-25. PMID:16280589. |
dual pyy(3-36) inhibition of both npy and pomc cells may temporarily reduce the contribution of arcuate cells to feeding circuits, enhancing the role of other cns loci. |
2006-01-25 |
2023-08-12 |
Not clear |
| Star W Lee, B Glenn Stanle. NMDA receptors mediate feeding elicited by neuropeptide Y in the lateral and perifornical hypothalamus. Brain research. vol 1063. issue 1. 2006-01-23. PMID:16259968. |
neuropeptide y (npy) and n-methyl-d-aspartate (nmda) receptors in the lateral (lh) and perifornical hypothalamus (pfh) are believed to be involved in the stimulation of feeding behavior. |
2006-01-23 |
2023-08-12 |
rat |
| Star W Lee, B Glenn Stanle. NMDA receptors mediate feeding elicited by neuropeptide Y in the lateral and perifornical hypothalamus. Brain research. vol 1063. issue 1. 2006-01-23. PMID:16259968. |
to investigate the possibility that neurons with these receptors interact to stimulate eating, the nmda receptor antagonists d-(-)-2-amino-5-phosphonopentanoic acid (d-ap5) or 7-chlorokynurenic acid (7-ck) were injected into the lh or pfh of satiated rats 5 min prior to npy in the same site and subsequent food intake was measured 1, 2, and 4 h postinjection. |
2006-01-23 |
2023-08-12 |
rat |
| Star W Lee, B Glenn Stanle. NMDA receptors mediate feeding elicited by neuropeptide Y in the lateral and perifornical hypothalamus. Brain research. vol 1063. issue 1. 2006-01-23. PMID:16259968. |
the injection of npy (78 pmol/0.3 microl acsf) in the pfh produced an average food intake of 9.7 g in 4 h, compared to the intake of 1.3 g after the artificial cerebrospinal fluid (acsf) vehicle. |
2006-01-23 |
2023-08-12 |
rat |
| Star W Lee, B Glenn Stanle. NMDA receptors mediate feeding elicited by neuropeptide Y in the lateral and perifornical hypothalamus. Brain research. vol 1063. issue 1. 2006-01-23. PMID:16259968. |
consistent with the effects of d-ap5, the nmda receptor antagonist 7-ck (40 nmol/0.3 microl dimethyl sulfoxide, dmso) suppressed feeding elicited by npy in the lh by 78%. |
2006-01-23 |
2023-08-12 |
rat |
| Star W Lee, B Glenn Stanle. NMDA receptors mediate feeding elicited by neuropeptide Y in the lateral and perifornical hypothalamus. Brain research. vol 1063. issue 1. 2006-01-23. PMID:16259968. |
collectively, the findings suggest that the feeding elicited by npy is dependent upon the activation of the nmda receptors in the lh and pfh. |
2006-01-23 |
2023-08-12 |
rat |
| Michel Félétou, Nigel R Leven. Neuropeptide Y2 receptors as drug targets for the central regulation of body weight. Current opinion in investigational drugs (London, England : 2000). vol 6. issue 10. 2006-01-06. PMID:16259221. |
stimulation of npy y2 receptors with synthetic peptide ligands or the gut derived peptide py3-36 has been shown to reduce food intake. |
2006-01-06 |
2023-08-12 |
Not clear |
| Michel Félétou, Nigel R Leven. Neuropeptide Y2 receptors as drug targets for the central regulation of body weight. Current opinion in investigational drugs (London, England : 2000). vol 6. issue 10. 2006-01-06. PMID:16259221. |
stimulation of the npy y2 subtype at these sites produces a wide array of effects unrelated to changes in food intake. |
2006-01-06 |
2023-08-12 |
Not clear |
| Matthew J Paul, David A Freeman, Jin Ho Park, John Dar. Neuropeptide Y induces torpor-like hypothermia in Siberian hamsters. Brain research. vol 1055. issue 1-2. 2006-01-03. PMID:16098953. |
npy decreased 24-h food intake and this was exaggerated in the animals reaching criterion for torpor; the decrease in food intake was positively correlated with the magnitude of the decrease in tb. |
2006-01-03 |
2023-08-12 |
rat |
| Eva Gropp, Marya Shanabrough, Erzsebet Borok, Allison W Xu, Ruth Janoschek, Thorsten Buch, Leona Plum, Nina Balthasar, Brigitte Hampel, Ari Waisman, Gregory S Barsh, Tamas L Horvath, Jens C Brünin. Agouti-related peptide-expressing neurons are mandatory for feeding. Nature neuroscience. vol 8. issue 10. 2005-12-07. PMID:16158063. |
nevertheless, inactivation of the genes encoding npy and/or agrp has no impact on food intake in mice. |
2005-12-07 |
2023-08-12 |
mouse |
| Scott M Sternson, Gordon M G Shepherd, Jeffrey M Friedma. Topographic mapping of VMH --> arcuate nucleus microcircuits and their reorganization by fasting. Nature neuroscience. vol 8. issue 10. 2005-12-07. PMID:16172601. |
in the hypothalamic arcuate nucleus (arc), pro-opiomelanocortin (pomc) neurons inhibit feeding and neuropeptide-y (npy) neurons stimulate feeding. |
2005-12-07 |
2023-08-12 |
mouse |
| Yvan Dumont, Emmanuel Moyse, Alain Fournier, Rémi Quirio. Evidence for the existence of an additional class of neuropeptide Y receptor sites in rat brain. The Journal of pharmacology and experimental therapeutics. vol 315. issue 1. 2005-11-28. PMID:15947033. |
these results suggest the possible existence of at least one additional subtype of npy receptor sites in the rat brain, with enrichment seen in midbrain and brainstem areas involved in the regulation of food intake and cardiorespiratory parameters. |
2005-11-28 |
2023-08-12 |
human |
| Nicholas W Gilpin, Robert B Stewart, James M Murphy, Nancy E Badia-Elde. Sensitized effects of neuropeptide Y on multiple ingestive behaviors in P rats following ethanol abstinence. Pharmacology, biochemistry, and behavior. vol 81. issue 4. 2005-11-28. PMID:16023707. |
npy increased food intake in all groups, and this effect was greater following ethanol abstinence. |
2005-11-28 |
2023-08-12 |
rat |
| Serge Luquet, Francisco A Perez, Thomas S Hnasko, Richard D Palmite. NPY/AgRP neurons are essential for feeding in adult mice but can be ablated in neonates. Science (New York, N.Y.). vol 310. issue 5748. 2005-11-23. PMID:16254186. |
hypothalamic neurons that express neuropeptide y (npy) and agouti-related protein (agrp) are thought to be critical regulators of feeding behavior and body weight. |
2005-11-23 |
2023-08-12 |
mouse |
| Kevin M Gamber, Heather Macarthur, Thomas C Westfal. Cannabinoids augment the release of neuropeptide Y in the rat hypothalamus. Neuropharmacology. vol 49. issue 5. 2005-10-31. PMID:15949823. |
neuropeptide y (npy) is one of the most potent orexigenic factors and is a key mediator in the hypothalamic control of food intake. |
2005-10-31 |
2023-08-12 |
rat |