| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jessica D Coppola, Barbara A Horwitz, Jock Hamilton, James E Blevins, Roger B McDonal. Reduced feeding response to muscimol and neuropeptide Y in senescent F344 rats. American journal of physiology. Regulatory, integrative and comparative physiology. vol 288. issue 6. 2005-06-15. PMID:15731400. |
senescent rats exhibited an attenuated npy-induced food intake, no increase in response to mus, and a response to npy + mus that was no larger than that of npy alone. |
2005-06-15 |
2023-08-12 |
rat |
| Jessica D Coppola, Barbara A Horwitz, Jock Hamilton, James E Blevins, Roger B McDonal. Reduced feeding response to muscimol and neuropeptide Y in senescent F344 rats. American journal of physiology. Regulatory, integrative and comparative physiology. vol 288. issue 6. 2005-06-15. PMID:15731400. |
we conclude that pvn injections of gaba, as well as npy, are less effective in stimulating feeding in senescent rats and suggest that alterations in their signaling pathways play a role in the involuntary feeding decrease seen near the end of life. |
2005-06-15 |
2023-08-12 |
rat |
| Yih-Shou Hsieh, Jeng-Dong Hsu, Shun-Fa Yang, Dong-Yih Ku. Immunohistochemical and genomic evidence for the involvement of hypothalamic neuropeptide Y (NPY) in phenylpropranolamine-mediated appetite suppression. Peptides. vol 25. issue 12. 2005-06-07. PMID:15572205. |
our results provided immunohistochemical and genomic evidence to suggest that ppa might reduce feeding by altering npy gene expression. |
2005-06-07 |
2023-08-12 |
rat |
| Ei-Suke Saito, Hiroyuki Kaiya, Tetsuya Tachibana, Shozo Tomonaga, D Michel Denbow, Kenji Kangawa, Mitsuhiro Furus. Inhibitory effect of ghrelin on food intake is mediated by the corticotropin-releasing factor system in neonatal chicks. Regulatory peptides. vol 125. issue 1-3. 2005-05-24. PMID:15582733. |
it is known that, in rats, central and peripheral ghrelin increases food intake mainly through activation of neuropeptide y (npy) neurons. |
2005-05-24 |
2023-08-12 |
rat |
| Ei-Suke Saito, Hiroyuki Kaiya, Tetsuya Tachibana, Shozo Tomonaga, D Michel Denbow, Kenji Kangawa, Mitsuhiro Furus. Inhibitory effect of ghrelin on food intake is mediated by the corticotropin-releasing factor system in neonatal chicks. Regulatory peptides. vol 125. issue 1-3. 2005-05-24. PMID:15582733. |
in addition, we also investigated the effect of ghrelin on npy-induced food intake and on expression of hypothalamic npy mrna. |
2005-05-24 |
2023-08-12 |
rat |
| Ei-Suke Saito, Hiroyuki Kaiya, Tetsuya Tachibana, Shozo Tomonaga, D Michel Denbow, Kenji Kangawa, Mitsuhiro Furus. Inhibitory effect of ghrelin on food intake is mediated by the corticotropin-releasing factor system in neonatal chicks. Regulatory peptides. vol 125. issue 1-3. 2005-05-24. PMID:15582733. |
co-injection of ghrelin with npy inhibited npy-induced increase in food intake, and the icv injection of ghrelin did not change npy mrna expression. |
2005-05-24 |
2023-08-12 |
rat |
| Ei-Suke Saito, Hiroyuki Kaiya, Tetsuya Tachibana, Shozo Tomonaga, D Michel Denbow, Kenji Kangawa, Mitsuhiro Furus. Inhibitory effect of ghrelin on food intake is mediated by the corticotropin-releasing factor system in neonatal chicks. Regulatory peptides. vol 125. issue 1-3. 2005-05-24. PMID:15582733. |
these results indicate that central ghrelin does not interact with npy as seen in rodents, but instead inhibits food intake by interacting with the endogenous crf and its receptor. |
2005-05-24 |
2023-08-12 |
rat |
| Thomas R Stratford, David Wirtshafte. NPY mediates the feeding elicited by muscimol injections into the nucleus accumbens shell. Neuroreport. vol 15. issue 17. 2005-05-16. PMID:15570176. |
npy mediates the feeding elicited by muscimol injections into the nucleus accumbens shell. |
2005-05-16 |
2023-08-12 |
rat |
| Thomas R Stratford, David Wirtshafte. NPY mediates the feeding elicited by muscimol injections into the nucleus accumbens shell. Neuroreport. vol 15. issue 17. 2005-05-16. PMID:15570176. |
this suggests that the npy system may participate in the expression of acbsh-mediated feeding behavior. |
2005-05-16 |
2023-08-12 |
rat |
| Thomas R Stratford, David Wirtshafte. NPY mediates the feeding elicited by muscimol injections into the nucleus accumbens shell. Neuroreport. vol 15. issue 17. 2005-05-16. PMID:15570176. |
our results suggest that the acbsh influences food intake, in part, through the release of npy. |
2005-05-16 |
2023-08-12 |
rat |
| Toshiro Kishi, Carl J Aschkenasi, Brian J Choi, Marisol E Lopez, Charlotte E Lee, Hongyan Liu, Anthony N Hollenberg, Jeffrey M Friedman, Joel K Elmquis. Neuropeptide Y Y1 receptor mRNA in rodent brain: distribution and colocalization with melanocortin-4 receptor. The Journal of comparative neurology. vol 482. issue 3. 2005-05-12. PMID:15690487. |
the central neuropeptide y (npy) y1 receptor (y1-r) system has been implicated in feeding, endocrine, and autonomic regulation. |
2005-05-12 |
2023-08-12 |
mouse |
| Eduardo J B Ramos, Michael M Meguid, Antonio C L Campos, Julio C U Coelh. Neuropeptide Y, alpha-melanocyte-stimulating hormone, and monoamines in food intake regulation. Nutrition (Burbank, Los Angeles County, Calif.). vol 21. issue 2. 2005-05-11. PMID:15723758. |
two main systems are implicated in food intake regulation: neuropeptide y (npy) and pro-opiomelanocortin. |
2005-05-11 |
2023-08-12 |
Not clear |
| Eduardo J B Ramos, Michael M Meguid, Antonio C L Campos, Julio C U Coelh. Neuropeptide Y, alpha-melanocyte-stimulating hormone, and monoamines in food intake regulation. Nutrition (Burbank, Los Angeles County, Calif.). vol 21. issue 2. 2005-05-11. PMID:15723758. |
the predominant npy orexigenic receptors are npy-y1 and npy-y5, and the two anorexigenic melanocortin receptors involved in hypothalamic food intake control are mc3-r and mc4-r. |
2005-05-11 |
2023-08-12 |
Not clear |
| Zhiyuan Hu, Seung Hun Cha, Goedelle van Haasteren, Jing Wang, M Daniel Lan. Effect of centrally administered C75, a fatty acid synthase inhibitor, on ghrelin secretion and its downstream effects. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 11. 2005-05-09. PMID:15728730. |
these effects closely correlate with appropriate changes downstream in the expression of the hypothalamic neuropeptides that regulate feeding behavior, i.e., down-regulation of the expression of npy and agrp and up-regulation of the expression of proopiomelanocortin/alpha-melanocyte-stimulating hormone, provoked by c75 and reversed by ghrelin. |
2005-05-09 |
2023-08-12 |
Not clear |
| D R Gehler. Introduction to the reviews on neuropeptide Y. Neuropeptides. vol 38. issue 4. 2005-05-05. PMID:15337366. |
while initial findings identified npy is an important contributor to the regulation of feeding, body weight and blood pressure, more recent work as revealed more subtle functions of this peptide and its potential role in affective disorders, bone formation and cravings. |
2005-05-05 |
2023-08-12 |
Not clear |
| D Larhammar, E Salanec. Molecular evolution of NPY receptor subtypes. Neuropeptides. vol 38. issue 4. 2005-05-05. PMID:15337367. |
nevertheless, teleost fishes seem to respond to npy with increased feeding why some other subtype probably mediates this effect. |
2005-05-05 |
2023-08-12 |
zebrafish |
| Norman Koglin, Annette G Beck-Sickinge. Novel modified and radiolabelled neuropeptide Y analogues to study Y-receptor subtypes. Neuropeptides. vol 38. issue 4. 2005-05-05. PMID:15337368. |
besides the important role of npy in the regulation of food intake and other physiological functions, recently npy receptors have been identified to play an important role in several types of cancer. |
2005-05-05 |
2023-08-12 |
Not clear |
| S P Kalra, P S Kalr. NPY and cohorts in regulating appetite, obesity and metabolic syndrome: beneficial effects of gene therapy. Neuropeptides. vol 38. issue 4. 2005-05-05. PMID:15337372. |
the circadian and ultradian rhythmicities in npy secretion imprint the daily circadian and episodic feeding patterns. |
2005-05-05 |
2023-08-12 |
Not clear |
| Thierry Pedrazzin. Importance of NPY Y1 receptor-mediated pathways: assessment using NPY Y1 receptor knockouts. Neuropeptides. vol 38. issue 4. 2005-05-05. PMID:15337379. |
the peptidic neurotransmitter neuropeptide y (npy) has been functionally implicated in feeding behavior, cardiovascular regulation, control of neuroendocrine axes, affective disorders, seizures, and memory retention. |
2005-05-05 |
2023-08-12 |
mouse |
| Ryang Yeo Kim, Seung Woo Shin, Byung Jin Kim, Weontae Lee, Ja-Hyun Bai. Dynamic regulation of hypothalamic neuropeptide gene expression and food intake by melanocortin analogues and reversal with melanocortin-4 receptor antagonist. Biochemical and biophysical research communications. vol 329. issue 4. 2005-05-03. PMID:15766551. |
administration of jkc-363, a selective mc4r-specific antagonist, coupled with [gln(6)]alpha-msh-nd, specifically reversed the [gln(6)]alpha-msh-nd-induced inhibition of food intake, but also reversed the hypothalamic expression levels of neuropeptides such as agrp, npy, mch, and pomc, which suggests [gln(6)]alpha-msh-nd can function as a selective mc4r agonist. |
2005-05-03 |
2023-08-12 |
mouse |