| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S P Kalra, P S Kalr. NPY and cohorts in regulating appetite, obesity and metabolic syndrome: beneficial effects of gene therapy. Neuropeptides. vol 38. issue 4. 2005-05-05. PMID:15337372. |
the circadian and ultradian rhythmicities in npy secretion imprint the daily circadian and episodic feeding patterns. |
2005-05-05 |
2023-08-12 |
Not clear |
| Thierry Pedrazzin. Importance of NPY Y1 receptor-mediated pathways: assessment using NPY Y1 receptor knockouts. Neuropeptides. vol 38. issue 4. 2005-05-05. PMID:15337379. |
the peptidic neurotransmitter neuropeptide y (npy) has been functionally implicated in feeding behavior, cardiovascular regulation, control of neuroendocrine axes, affective disorders, seizures, and memory retention. |
2005-05-05 |
2023-08-12 |
mouse |
| Ryang Yeo Kim, Seung Woo Shin, Byung Jin Kim, Weontae Lee, Ja-Hyun Bai. Dynamic regulation of hypothalamic neuropeptide gene expression and food intake by melanocortin analogues and reversal with melanocortin-4 receptor antagonist. Biochemical and biophysical research communications. vol 329. issue 4. 2005-05-03. PMID:15766551. |
administration of jkc-363, a selective mc4r-specific antagonist, coupled with [gln(6)]alpha-msh-nd, specifically reversed the [gln(6)]alpha-msh-nd-induced inhibition of food intake, but also reversed the hypothalamic expression levels of neuropeptides such as agrp, npy, mch, and pomc, which suggests [gln(6)]alpha-msh-nd can function as a selective mc4r agonist. |
2005-05-03 |
2023-08-12 |
mouse |
| I G A Kiris, O T Eroldoğan, M Kir, M Kuml. Influence of neuropeptide Y (NPY) on food intake and growth of penaeid shrimps Marsupenaeus japonicus and Penaeus semisulcatus (Decapoda: Penaeidae). Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 139. issue 2. 2005-04-18. PMID:15528173. |
influence of neuropeptide y (npy) on food intake and growth of penaeid shrimps marsupenaeus japonicus and penaeus semisulcatus (decapoda: penaeidae). |
2005-04-18 |
2023-08-12 |
Not clear |
| I G A Kiris, O T Eroldoğan, M Kir, M Kuml. Influence of neuropeptide Y (NPY) on food intake and growth of penaeid shrimps Marsupenaeus japonicus and Penaeus semisulcatus (Decapoda: Penaeidae). Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 139. issue 2. 2005-04-18. PMID:15528173. |
in experiment 1, food intake (fi) of marsupenaeus japonicus pls (0.96 g), injected with npy at 0.6 microg per g bw, was investigated within 48 h posttreatment. |
2005-04-18 |
2023-08-12 |
Not clear |
| I G A Kiris, O T Eroldoğan, M Kir, M Kuml. Influence of neuropeptide Y (NPY) on food intake and growth of penaeid shrimps Marsupenaeus japonicus and Penaeus semisulcatus (Decapoda: Penaeidae). Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 139. issue 2. 2005-04-18. PMID:15528173. |
the present findings indicated for the first time that npy is a potent stimulator of food intake when administered either intramuscularly or orally to penaeid shrimps. |
2005-04-18 |
2023-08-12 |
Not clear |
| Nina Pronchuk, William F Colmer. NPY presynaptic actions are reduced in the hypothalamic mpPVN of obese (fa/fa), but not lean, Zucker rats in vitro. British journal of pharmacology. vol 141. issue 6. 2005-04-11. PMID:14967739. |
neuropeptide y (npy) profoundly enhances feeding when injected intracerebroventricularly, or directly into hypothalamic nuclei, such as the paraventricular nucleus (pvn). |
2005-04-11 |
2023-08-12 |
rat |
| Nina Pronchuk, William F Colmer. NPY presynaptic actions are reduced in the hypothalamic mpPVN of obese (fa/fa), but not lean, Zucker rats in vitro. British journal of pharmacology. vol 141. issue 6. 2005-04-11. PMID:14967739. |
paradoxically, npy has a reduced action on feeding in obese zucker rats relative to lean zucker rats, although the obese rats have much higher levels of hypothalamic npy expression. |
2005-04-11 |
2023-08-12 |
rat |
| Sheng Bi, Karen A Scott, Jayson Hyun, Ellen E Ladenheim, Timothy H Mora. Running wheel activity prevents hyperphagia and obesity in Otsuka long-evans Tokushima Fatty rats: role of hypothalamic signaling. Endocrinology. vol 146. issue 4. 2005-04-08. PMID:15625240. |
together, these data suggest that the elevation of dmh crf expression may mediate the short-term feeding inhibitory effects of exercise and that exercise limits the elevation of dmh npy expression to account for the overall prevention of oletf rats' obesity. |
2005-04-08 |
2023-08-12 |
rat |
| B K Whitlock, J A Daniel, C D McMahon, F C Buonomo, C G Wagner, B Steele, J L Sarti. Intracerebroventricular melanin-concentrating hormone stimulates food intake in sheep. Domestic animal endocrinology. vol 28. issue 2. 2005-04-08. PMID:15713369. |
food intake was measured for 2 h before and at 2, 4, 6, 8, 12 and 24 h. in this experiment, feed intake was increased (pnpy treated sheep only. |
2005-04-08 |
2023-08-12 |
rat |
| B K Whitlock, J A Daniel, C D McMahon, F C Buonomo, C G Wagner, B Steele, J L Sarti. Intracerebroventricular melanin-concentrating hormone stimulates food intake in sheep. Domestic animal endocrinology. vol 28. issue 2. 2005-04-08. PMID:15713369. |
in the second experiment, the same sheep were fed to satiety and then randomized to receive one of six treatments [saline and either 0.1, 1.0 or 5.0 nmol/kg mch, 0.1 nmol/kg npy, or mch+npy (0.1 nmol/kg)] injected icv over 30 s. food intake was measured for 2 h before and at 2, 4, 6, 8, 12, and 24 h after icv injection. |
2005-04-08 |
2023-08-12 |
rat |
| B K Whitlock, J A Daniel, C D McMahon, F C Buonomo, C G Wagner, B Steele, J L Sarti. Intracerebroventricular melanin-concentrating hormone stimulates food intake in sheep. Domestic animal endocrinology. vol 28. issue 2. 2005-04-08. PMID:15713369. |
all doses of mch as well as npy resulted in greater (pfood intake than saline. |
2005-04-08 |
2023-08-12 |
rat |
| R Fernandez-Fernandez, E Aguilar, M Tena-Sempere, L Pinill. Effects of polypeptide YY(3-36) upon luteinizing hormone-releasing hormone and gonadotropin secretion in prepubertal rats: in vivo and in vitro studies. Endocrinology. vol 146. issue 3. 2005-04-04. PMID:15564330. |
polypeptide yy(3-36) (pyy(3-36)) is a gastrointestinal secreted molecule, agonist of neuropeptide y (npy) receptor subtypes y2 and y5, recently involved in the control of food intake. |
2005-04-04 |
2023-08-12 |
rat |
| Kanji A Takahashi, Roger D Con. Fasting induces a large, leptin-dependent increase in the intrinsic action potential frequency of orexigenic arcuate nucleus neuropeptide Y/Agouti-related protein neurons. Endocrinology. vol 146. issue 3. 2005-04-04. PMID:15591135. |
the neuropeptide y (npy)/agouti-related protein (agrp) neurons of the hypothalamic arcuate nucleus are thought to promote feeding. |
2005-04-04 |
2023-08-12 |
mouse |
| Kishor Bugarith, Thu T Dinh, Ai-Jun Li, Robert C Speth, Sue Ritte. Basomedial hypothalamic injections of neuropeptide Y conjugated to saporin selectively disrupt hypothalamic controls of food intake. Endocrinology. vol 146. issue 3. 2005-04-04. PMID:15604214. |
we injected npy-sap into the basomedial hypothalamus (bmh), just dorsal to the arcuate nucleus (arc), to investigate its neurotoxicity and to determine whether arc npy neurons are required for glucoprivic feeding. |
2005-04-04 |
2023-08-12 |
Not clear |
| Kishor Bugarith, Thu T Dinh, Ai-Jun Li, Robert C Speth, Sue Ritte. Basomedial hypothalamic injections of neuropeptide Y conjugated to saporin selectively disrupt hypothalamic controls of food intake. Endocrinology. vol 146. issue 3. 2005-04-04. PMID:15604214. |
thus, npy-sap destroyed npy receptor-expressing neurons in the arc and selectively disrupted controls of feeding dependent on those neurons but did not disrupt peptidergic or metabolic controls dependent upon circuitry outside the bmh. |
2005-04-04 |
2023-08-12 |
Not clear |
| P J King, G William. Role of ARC NPY neurons in energy homeostasis. Drug news & perspectives. vol 11. issue 7. 2005-03-30. PMID:15616681. |
the most noticeable effect of npy is the stimulation of feeding. |
2005-03-30 |
2023-08-12 |
human |
| P J King, G William. Role of ARC NPY neurons in energy homeostasis. Drug news & perspectives. vol 11. issue 7. 2005-03-30. PMID:15616681. |
the recent isolation and cloning of a rat npy receptor with the required pharmacology for the feeding response, called the y(5) receptor, has led to the suggestion that this is the "feeding" receptor. |
2005-03-30 |
2023-08-12 |
human |
| Christine G Wagner, Chris D McMahon, Daniel L Marks, Joseph A Daniel, Barbara Steele, James L Sarti. A role for agouti-related protein in appetite regulation in a species with continuous nutrient delivery. Neuroendocrinology. vol 80. issue 4. 2005-03-29. PMID:15604600. |
a 4th study was done to investigate the interactions of agrp and neuropeptide y (npy) on food intake over a 24-hour period. |
2005-03-29 |
2023-08-12 |
mouse |
| Christine G Wagner, Chris D McMahon, Daniel L Marks, Joseph A Daniel, Barbara Steele, James L Sarti. A role for agouti-related protein in appetite regulation in a species with continuous nutrient delivery. Neuroendocrinology. vol 80. issue 4. 2005-03-29. PMID:15604600. |
intracerebroventricular injections of either agrp or npy significantly increased cumulative food intake over saline controls. |
2005-03-29 |
2023-08-12 |
mouse |