| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jing He, Amit Varma, Lisa A Weissfeld, Sherin U Devaska. Postnatal glucocorticoid exposure alters the adult phenotype. American journal of physiology. Regulatory, integrative and comparative physiology. vol 287. issue 1. 2004-07-13. PMID:15001431. |
we conclude that postnatal dex treatment causes permanent sex-specific changes in the adult phenotype, setting the stage for future development of diabetes (increased glucose:insulin ratio), obesity (increased npy and food intake), and neurological impairment (loss of cerebral volume). |
2004-07-13 |
2023-08-12 |
rat |
| Tami Wolden-Hanson, Brett T Marck, Alvin M Matsumot. Blunted hypothalamic neuropeptide gene expression in response to fasting, but preservation of feeding responses to AgRP in aging male Brown Norway rats. American journal of physiology. Regulatory, integrative and comparative physiology. vol 287. issue 1. 2004-07-13. PMID:15001433. |
to test the food intake response to appetite-stimulating neuropeptides, y, m, o, and very old (vo; 33 mo) rats (n = 4-8/group) received one intracerebroventricular injection of each of three treatments: 0.1 nmol agrp, 2.34 nmol npy, and saline control. |
2004-07-13 |
2023-08-12 |
rat |
| Tami Wolden-Hanson, Brett T Marck, Alvin M Matsumot. Blunted hypothalamic neuropeptide gene expression in response to fasting, but preservation of feeding responses to AgRP in aging male Brown Norway rats. American journal of physiology. Regulatory, integrative and comparative physiology. vol 287. issue 1. 2004-07-13. PMID:15001433. |
in contrast, npy increased food intake more in y than in older animals and its effects did not last >24 h. we conclude that the mechanisms by which arcuate nucleus neurons influence appetite are differentially affected by age and speculate that the melanocortin system may be a useful target for treatment of the anorexia of aging. |
2004-07-13 |
2023-08-12 |
rat |
| Jessica D Coppola, Barbara A Horwitz, Jock Hamilton, Roger B McDonal. Expression of NPY Y1 and Y5 receptors in the hypothalamic paraventricular nucleus of aged Fischer 344 rats. American journal of physiology. Regulatory, integrative and comparative physiology. vol 287. issue 1. 2004-07-13. PMID:15044185. |
the spontaneous decrease in food intake and body weight is associated with attenuated responses to intracerebroventricular injections of neuropeptide y (npy) compared with old presenescent or with young adult rats. |
2004-07-13 |
2023-08-12 |
rat |
| Jessica D Coppola, Barbara A Horwitz, Jock Hamilton, Roger B McDonal. Expression of NPY Y1 and Y5 receptors in the hypothalamic paraventricular nucleus of aged Fischer 344 rats. American journal of physiology. Regulatory, integrative and comparative physiology. vol 287. issue 1. 2004-07-13. PMID:15044185. |
in the present study, we tested the hypothesis that this blunted responsiveness involves the number and expression of hypothalamic paraventricular nucleus (pvn) y(1) and/or y(5) npy receptors, both of which are thought to mediate npy-induced food intake. |
2004-07-13 |
2023-08-12 |
rat |
| O Della-Zuana, L Revereault, A Beck-Sickinger, A Monge, D-H Caignard, J-L Fauchère, J-M Henlin, V Audinot, J A Boutin, S Chamorro, M Félétou, N Leven. A potent and selective NPY Y5 antagonist reduces food intake but not through blockade of the NPY Y5 receptor. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. vol 28. issue 4. 2004-07-09. PMID:14758341. |
a potent and selective npy y5 antagonist reduces food intake but not through blockade of the npy y5 receptor. |
2004-07-09 |
2023-08-12 |
Not clear |
| O Della-Zuana, L Revereault, A Beck-Sickinger, A Monge, D-H Caignard, J-L Fauchère, J-M Henlin, V Audinot, J A Boutin, S Chamorro, M Félétou, N Leven. A potent and selective NPY Y5 antagonist reduces food intake but not through blockade of the NPY Y5 receptor. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. vol 28. issue 4. 2004-07-09. PMID:14758341. |
these studies were performed to test the hypothesis that endogenous neuropeptide y (npy) acting on the npy y(5) receptor subtype contributes to the control of food intake. |
2004-07-09 |
2023-08-12 |
Not clear |
| H Y Chen, M E Trumbauer, A S Chen, D T Weingarth, J R Adams, E G Frazier, Z Shen, D J Marsh, S D Feighner, X-M Guan, Z Ye, R P Nargund, R G Smith, L H T Van der Ploeg, A D Howard, D J MacNeil, S Qia. Orexigenic action of peripheral ghrelin is mediated by neuropeptide Y and agouti-related protein. Endocrinology. vol 145. issue 6. 2004-06-24. PMID:14962995. |
pharmacological evidence indicates that ghrelin's effects on food intake are mediated by neuropeptide y (npy) and agouti-related protein (agrp) in the central nervous system. |
2004-06-24 |
2023-08-12 |
mouse |
| Abelardo Aguilera, Rosa Codoceo, María A Bajo, Pedro Iglesias, Juan J Diéz, Guillermina Barril, Secundino Cigarrán, Vicente Alvarez, Olga Celadilla, Antonio Fernández-Perpén, Agustín Montero, Rafael Selga. Eating behavior disorders in uremia: a question of balance in appetite regulation. Seminars in dialysis. vol 17. issue 1. 2004-06-21. PMID:14717811. |
high levels of cholecystokinin (cck) (a powerful anorexigen) are associated with early satiety for carbohydrates and neuropeptide y (npy) (an orexigen) with repeated food intake. |
2004-06-21 |
2023-08-12 |
Not clear |
| Ai-Jun Li, Sue Ritte. Glucoprivation increases expression of neuropeptide Y mRNA in hindbrain neurons that innervate the hypothalamus. The European journal of neuroscience. vol 19. issue 8. 2004-06-18. PMID:15090041. |
while the specific roles of these distinct sources of innervation are not known, npy neurotransmission within the hypothalamus appears to contribute to glucoregulatory feeding. |
2004-06-18 |
2023-08-12 |
rat |
| Ai-Jun Li, Sue Ritte. Glucoprivation increases expression of neuropeptide Y mRNA in hindbrain neurons that innervate the hypothalamus. The European journal of neuroscience. vol 19. issue 8. 2004-06-18. PMID:15090041. |
the responsiveness of hindbrain npy neurons to glucose deficit suggests that these neurons participate in glucoprivic feeding or other glucoregulatory responses. |
2004-06-18 |
2023-08-12 |
rat |
| Satya P Kalra, Pushpa S Kalr. Neuropeptide Y: a physiological orexigen modulated by the feedback action of ghrelin and leptin. Endocrine. vol 22. issue 1. 2004-06-17. PMID:14610298. |
episodic npy neurosecretion in hypothalamic target sites is temporally linked with onset of the daily feeding pattern. |
2004-06-17 |
2023-08-12 |
Not clear |
| Satya P Kalra, Pushpa S Kalr. Neuropeptide Y: a physiological orexigen modulated by the feedback action of ghrelin and leptin. Endocrine. vol 22. issue 1. 2004-06-17. PMID:14610298. |
npy receptors, y1, y2, and y5, expressed by various components of the npy network, mediate npy-induced feeding. |
2004-06-17 |
2023-08-12 |
Not clear |
| E J Crespi, H Vaudry, R J Denve. Roles of corticotropin-releasing factor, neuropeptide Y and corticosterone in the regulation of food intake in Xenopus laevis. Journal of neuroendocrinology. vol 16. issue 3. 2004-06-15. PMID:15049859. |
in mammals, hypothalamic control of food intake involves counterregulation of appetite by an orexigenic peptides such as corticotropin-releasing factor (crf), and orexigenic peptides such as neuropeptide y (npy). |
2004-06-15 |
2023-08-12 |
xenopus_laevis |
| E J Crespi, H Vaudry, R J Denve. Roles of corticotropin-releasing factor, neuropeptide Y and corticosterone in the regulation of food intake in Xenopus laevis. Journal of neuroendocrinology. vol 16. issue 3. 2004-06-15. PMID:15049859. |
glucocorticoids also stimulate food intake by inhibiting crf while facilitating npy actions. |
2004-06-15 |
2023-08-12 |
xenopus_laevis |
| E J Crespi, H Vaudry, R J Denve. Roles of corticotropin-releasing factor, neuropeptide Y and corticosterone in the regulation of food intake in Xenopus laevis. Journal of neuroendocrinology. vol 16. issue 3. 2004-06-15. PMID:15049859. |
to gain a better understanding of the diversity and evolution of neuroendocrine feeding controls in vertebrates, we analysed the effects of crf, npy and glucocorticoids on food intake in juvenile xenopus laevis. |
2004-06-15 |
2023-08-12 |
xenopus_laevis |
| E J Crespi, H Vaudry, R J Denve. Roles of corticotropin-releasing factor, neuropeptide Y and corticosterone in the regulation of food intake in Xenopus laevis. Journal of neuroendocrinology. vol 16. issue 3. 2004-06-15. PMID:15049859. |
injection of frog npy and short-term corticosterone treatment increased food intake. |
2004-06-15 |
2023-08-12 |
xenopus_laevis |
| E J Crespi, H Vaudry, R J Denve. Roles of corticotropin-releasing factor, neuropeptide Y and corticosterone in the regulation of food intake in Xenopus laevis. Journal of neuroendocrinology. vol 16. issue 3. 2004-06-15. PMID:15049859. |
semi-quantitative reverse transcription-polymerase chain reaction analyses showed that crf and npy mrna fluctuated with food intake in the brain region containing the mid-posterior hypothalamus, pretectum, and optic tectum: crf mrna decreased 6 h after a meal and remained low through 31 days of food deprivation; npy mrna content also decreased 6 h after a meal, but increased to prefeeding levels by 24 h. plasma corticosterone concentration increased 6 h after a meal, returned to prefeeding levels by 24 h, and did not change with prolonged food deprivation. |
2004-06-15 |
2023-08-12 |
xenopus_laevis |
| E J Crespi, H Vaudry, R J Denve. Roles of corticotropin-releasing factor, neuropeptide Y and corticosterone in the regulation of food intake in Xenopus laevis. Journal of neuroendocrinology. vol 16. issue 3. 2004-06-15. PMID:15049859. |
overall, our data support the conclusion that, similar to other vertebrates, crf is anorexigenic while npy is orexigenic in x. laevis, and crf secretion modulates food intake in the absence of stress by exerting an inhibitory tone on appetite. |
2004-06-15 |
2023-08-12 |
xenopus_laevis |
| Seung Hun Cha, Zhiyuan Hu, M Daniel Lan. Long-term effects of a fatty acid synthase inhibitor on obese mice: food intake, hypothalamic neuropeptides, and UCP3. Biochemical and biophysical research communications. vol 317. issue 2. 2004-06-01. PMID:15063757. |
decreased food intake correlated with decreased expression of hypothalamic neuropeptide mrnas for npy, agrp, and mch and an increased expression of neuropeptide mrnas for alphamsh (i.e., pomc) and cart. |
2004-06-01 |
2023-08-12 |
mouse |