Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Gareth P Harris, Vera M Hapiak, Rachel T Wragg, Sarah B Miller, Lindsay J Hughes, Robert J Hobson, Robert Steven, Bruce Bamber, Richard W Komunieck. Three distinct amine receptors operating at different levels within the locomotory circuit are each essential for the serotonergic modulation of chemosensation in Caenorhabditis elegans. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 5. 2009-02-24. PMID:19193891. |
in the present study, we examined the serotonergic stimulation of aversive responses to dilute octanol in animals containing null alleles of these 5-ht receptors. |
2009-02-24 |
2023-08-12 |
caenorhabditis_elegans |
Frederico G Graeff, Cristina M Del-Be. Neurobiology of panic disorder: from animal models to brain neuroimaging. Neuroscience and biobehavioral reviews. vol 32. issue 7. 2009-02-19. PMID:18573531. |
evidence from animal models of anxiety has led to the hypothesis that serotonin enhances inhibitory avoidance (related to anxiety) in the forebrain, but inhibits one-way escape (panic) in the midbrain periaqueductal gray (pag). |
2009-02-19 |
2023-08-12 |
rat |
Cladis L K Moraes, Leandro J Bertoglio, Antonio P Carobre. Interplay between glutamate and serotonin within the dorsal periaqueductal gray modulates anxiety-related behavior of rats exposed to the elevated plus-maze. Behavioural brain research. vol 194. issue 2. 2009-02-03. PMID:18675851. |
although both glutamate n-methyl-d-aspartic acid (nmda) and serotonin type 1-a (5-ht(1a)) receptors have been shown to interfere with these subtle responses, such as inhibitory avoidance, a possible interaction between them remains to be examined. |
2009-02-03 |
2023-08-12 |
rat |
Galina F Molodtsov. Serotonergic mechanisms of memory trace retrieval. Behavioural brain research. vol 195. issue 1. 2009-01-12. PMID:18243361. |
analysis of serotonin (5-ht) metabolism and specific binding of radioligand [(3)h]5-ht in various brain structures at different stages of a conditioned passive avoidance response in rats has demonstrated that 5-ht is involved in the processes of memory retrieval rather than in acquisition. |
2009-01-12 |
2023-08-12 |
rat |
b' Luisa E Galindo, Mar\\xc3\\xada Eugenia Gar\\xc3\\xadn-Aguilar, Andrea C Medina, Norma Seraf\\xc3\\xadn, Gina L Quirarte, Roberto A Prado-Alcal\\xc3\\xa. Acquisition and retention of enhanced active avoidance are unaffected by interference with serotonergic activity. Behavioural brain research. vol 195. issue 1. 2009-01-12. PMID:18342379.' |
these results indicate that the dose of pca administered, which is known to deplete cerebral serotonin, does not interfere with acquisition and retention of enhanced active avoidance training. |
2009-01-12 |
2023-08-12 |
rat |
Sven Ove Ogren, Therese M Eriksson, Elin Elvander-Tottie, Claudio D'Addario, Joanna C Ekström, Per Svenningsson, Björn Meister, Jan Kehr, Oliver Stied. The role of 5-HT(1A) receptors in learning and memory. Behavioural brain research. vol 195. issue 1. 2009-01-12. PMID:18394726. |
available results also implicate the 5-ht(1a) receptor in the retrieval of aversive or emotional memories, supporting an involvement in reconsolidation. |
2009-01-12 |
2023-08-12 |
Not clear |
Therese M Eriksson, Armita Golkar, Joanna C Ekström, Per Svenningsson, Sven Ove Ogre. 5-HT7 receptor stimulation by 8-OH-DPAT counteracts the impairing effect of 5-HT(1A) receptor stimulation on contextual learning in mice. European journal of pharmacology. vol 596. issue 1-3. 2009-01-12. PMID:18789922. |
the 5-ht(7) receptor antagonist (2r)-1-[(3-hydroxyphenyl)sulfonyl]-2-[2-(4-methyl-1-piperidinyl)ethyl] pyrrolidine (sb-269970) was combined with 8-oh-dpat to dissociate 5-ht(1a) from 5-ht(7) receptor-mediated effects, in the passive avoidance task for emotional learning. |
2009-01-12 |
2023-08-12 |
mouse |
Adriana Lourenço da Silva, Juliana G Ferreira, Bárbara da Silva Martins, Sabrina Oliveira, Nathalia Mai, Domingos S Nunes, Elaine Elisabetsk. Serotonin receptors contribute to the promnesic effects of P. olacoides (Marapuama). Physiology & behavior. vol 95. issue 1-2. 2008-12-18. PMID:18561960. |
the study reveals that poee promnesic effects on short-term (acquisition, consolidation and retrieval) and long-term (retrieval) declarative aversive memories are increased by 5ht(2a) (but not 5ht(1a)) serotonin antagonists (spiperone and pindolol, respectively). |
2008-12-18 |
2023-08-12 |
mouse |
S V Solntseva, V P Nikiti. Serotonin and NMDA glutamate receptor antagonists selectively impair the reactivation of associative memory in the common snail. Neuroscience and behavioral physiology. vol 38. issue 7. 2008-12-16. PMID:18709464. |
it is suggested that serotonin receptors are involved in the mechanisms underlying extraction of the memory trace of the aversive habit to the foodstuff in snails, while nmda glutamate receptors are involved in memory trace storage processes. |
2008-12-16 |
2023-08-12 |
Not clear |
S V Solntseva, V P Nikiti. [Neurochemical mechanisms of food aversion conditioning consolidation in snail helix lucorum]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 94. issue 8. 2008-10-28. PMID:18825927. |
food aversion conditioning was absent in snails after metiotepin, nonselective serotonin receptors antagonist, or after mk-801, nmda glutamate receptors antagonist, applications. |
2008-10-28 |
2023-08-12 |
Not clear |
D A F Robertson, J E Beattie, I C Reid, D J K Balfou. Influence of 5,7-dihydroxytryptamine lesions of the rat fornix-fimbria and cingulum bundles on spontaneous activity in an aversive maze. Journal of psychopharmacology (Oxford, England). vol 22. issue 3. 2008-10-23. PMID:18208913. |
this study explored the putative role of the principal 5-hydroxytryptamine (5-ht) neurones that project to the hippocampus from the median raphe nucleus in this response to an aversive environment by lesioning the 5-ht fibres that project through the fornix/fimbria and cingulum bundles. |
2008-10-23 |
2023-08-12 |
rat |
D A F Robertson, J E Beattie, I C Reid, D J K Balfou. Influence of 5,7-dihydroxytryptamine lesions of the rat fornix-fimbria and cingulum bundles on spontaneous activity in an aversive maze. Journal of psychopharmacology (Oxford, England). vol 22. issue 3. 2008-10-23. PMID:18208913. |
it is concluded that exposure to an explicitly aversive environment elicits a brief stimulation of the 5-ht neurones that project to the hippocampus from the median raphe nucleus and that this stimulation inhibits the initial burst of exploratory activity that is observed in animals placed in a less aversive novel environment. |
2008-10-23 |
2023-08-12 |
rat |
Therese M Eriksson, Nather Madjid, Elin Elvander-Tottie, Oliver Stiedl, Per Svenningsson, Sven Ove Ogre. Blockade of 5-HT 1B receptors facilitates contextual aversive learning in mice by disinhibition of cholinergic and glutamatergic neurotransmission. Neuropharmacology. vol 54. issue 7. 2008-10-14. PMID:18394658. |
this study examined the role of the 5-ht(1b) receptor in one-trial aversive contextual learning using the passive avoidance (pa) task in nmri mice. |
2008-10-14 |
2023-08-12 |
mouse |
Hsiun-Ing Chen, Li-Chun Lin, Lung Yu, Yu-Fan Liu, Yu-Min Kuo, A-Min Huang, Jih-Ing Chuang, Fong-Sen Wu, Pao-Chi Liao, Chauying J Je. Treadmill exercise enhances passive avoidance learning in rats: the role of down-regulated serotonin system in the limbic system. Neurobiology of learning and memory. vol 89. issue 4. 2008-07-15. PMID:17892954. |
moreover, pretreatment with 0.1 mg/kg 8-hydroxy-di-n-propylamino tetralin, a selective 5-ht(1a) receptor agonist, impaired the passive avoidance performance and completely abolished the exercise-enhanced fear memory. |
2008-07-15 |
2023-08-12 |
rat |
Alfred Beulig, Jonathan Fowle. Fish on Prozac: effect of serotonin reuptake inhibitors on cognition in goldfish. Behavioral neuroscience. vol 122. issue 2. 2008-06-03. PMID:18410181. |
in an active, two-way, shuttle-box avoidance task we compared escape and avoidance of shock among fish receiving chronic administration of fluoxetine (prozac), others receiving a 5-ht(1a) receptor antagonist (way 100,635; sigma, st. louis, mo) and controls. |
2008-06-03 |
2023-08-12 |
rat |
Milena de Barros Viana, Hélio Zangrossi, Gustavo Massaro Onusi. 5-HT1A receptors of the lateral septum regulate inhibitory avoidance but not escape behavior in rats. Pharmacology, biochemistry, and behavior. vol 89. issue 3. 2008-05-20. PMID:18282594. |
the data suggests that ls 5-ht(1a) receptors are involved in the control of inhibitory avoidance behavior and that a failure in this regulatory mechanism may be of importance to the physiopathology of generalized anxiety disorder. |
2008-05-20 |
2023-08-12 |
rat |
Peter Dayan, Quentin J M Huy. Serotonin, inhibition, and negative mood. PLoS computational biology. vol 4. issue 2. 2008-05-15. PMID:18248087. |
we show how a drop in behavioral inhibition, putatively resulting from an experimentally or psychiatrically influenced drop in serotonin, could result in unexpectedly large negative prediction errors and a significant aversive shift in reinforcement statistics. |
2008-05-15 |
2023-08-12 |
Not clear |
Peter Dayan, Quentin J M Huy. Serotonin, inhibition, and negative mood. PLoS computational biology. vol 4. issue 2. 2008-05-15. PMID:18248087. |
we suggest an interpretation of this finding that helps dissolve the apparent contradiction between the fact that inhibition of serotonin reuptake is the first-line treatment of depression, although serotonin itself is most strongly linked with aversive rather than appetitive outcomes and predictions. |
2008-05-15 |
2023-08-12 |
Not clear |
Lucinéia Dos Santos, Telma G C S de Andrade, Hélio Zangrossi Junio. 5-HT1A receptors in the dorsal hippocampus mediate the anxiogenic effect induced by the stimulation of 5-HT neurons in the median raphe nucleus. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 18. issue 4. 2008-04-23. PMID:17728111. |
intra-mrn administration of the excitatory amino acid kainic acid, which non-selectively stimulates 5-ht neurons in this brain area facilitated inhibitory avoidance and impaired escape performance, but also affected locomotion. |
2008-04-23 |
2023-08-12 |
rat |
Lucinéia Dos Santos, Telma G C S de Andrade, Hélio Zangrossi Junio. 5-HT1A receptors in the dorsal hippocampus mediate the anxiogenic effect induced by the stimulation of 5-HT neurons in the median raphe nucleus. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 18. issue 4. 2008-04-23. PMID:17728111. |
intra-mrn injection of way-100635, which has a disinhibitory effect on the activity of 5-ht neurons in this midbrain area, only facilitated inhibitory avoidance. |
2008-04-23 |
2023-08-12 |
rat |