| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Rex, J P Voigt, H Fin. Anxiety but not arousal increases 5-hydroxytryptamine release in the rat ventral hippocampus in vivo. The European journal of neuroscience. vol 22. issue 5. 2006-01-10. PMID:16176361. |
exposure to the x-maze for 20 min was accompanied by an 'anxious' behaviour in the rats and increased extracellular 5-ht to 165% of basal release, whereas exposure to a less aversive 'deactivated' plus maze (115+/-6%) or to white noise for 20 min in the familiar surroundings of the home cage (98+/-6%) did not change hippocampal 5-ht release significantly, despite similar behavioural activation indicated by increased locomotor activity. |
2006-01-10 |
2023-08-12 |
rat |
| G Telegdy, H Tiricz, A Adami. Involvement of neurotransmitters in urocortin-induced passive avoidance learning in mice. Brain research bulletin. vol 67. issue 3. 2005-12-15. PMID:16144661. |
d2, muscarinic cholinergic, alfa-adrenergic, crf, serotonergic (5ht 1-2), gaba b receptors are involved in the consolidation of the passive avoidance response. |
2005-12-15 |
2023-08-12 |
mouse |
| Machiko Matsumoto, Kasane Higuchi, Hiroko Togashi, Hiroyo Koseki, Taku Yamaguchi, Manabu Kanno, Mitsuhiro Yoshiok. Early postnatal stress alters the 5-HTergic modulation to emotional stress at postadolescent periods of rats. Hippocampus. vol 15. issue 6. 2005-10-13. PMID:15999341. |
these data suggest that aversive stress exposed at 2w is attributable to changes in the 5-ht(1a) receptor-mediated synaptic plasticity, which may be responsible for the attenuation of freezing behavior. |
2005-10-13 |
2023-08-12 |
rat |
| S Eccles, E-M Kim, E O'Har. Granisetron attenuates exercise-induced conditioned taste aversion in the rat. Appetite. vol 44. issue 3. 2005-09-26. PMID:15927732. |
a conditioned taste aversion (cta) paradigm was used in the present study to investigate whether cta produced by exercise could be attenuated by the 5-ht(3) receptor antagonist granisetron. |
2005-09-26 |
2023-08-12 |
human |
| A Swarowsky, A F Monteiro, L L Xavier, D M Zancan, M Achava. Serotonergic immunoreactivity in the pedal ganglia of the pulmonate snail Megalobulimus abbreviatus after thermal stimulus: A semi-quantitative analysis. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 141. issue 2. 2005-09-22. PMID:15979914. |
in the anterior neurons, significant differences (p < 0.01) were observed between the groups of animals stimulated at 50 degrees c and 22 degrees c and sacrificed after 6 h. in the medial neurons, significant differences (p < 0.05) were observed between the control group and the groups of animals stimulated at 50 degrees c and sacrificed after 6 and 24 h. neuropilar area 1 showed differences (p < 0.01) in 5ht-ir between the control group and the groups of animals stimulated at 50 degrees c and sacrificed after 3 and 24 h. neuropilar area 2 showed a significant difference (p < 0.05) between the groups of animals stimulated at 22 degrees c and sacrificed after 3 and 24 h. these results suggest the involvement of 5-ht in the nociceptive circuit of m. abbreviatus, mainly that of the medial neurons and neuropilar area 1, which showed increases in 5ht-ir after thermal aversive stimuli. |
2005-09-22 |
2023-08-12 |
Not clear |
| Anna Szúcs, Péter Halás. [Somnambulism: clinical and eletrophysiological aspects]. Orvosi hetilap. vol 146. issue 23. 2005-07-22. PMID:15988917. |
clonazepam and selective serotonin reuptake inhibitors prove sometimes effective, but the most effective methods in decreasing the frequency of somnambule episodes are the regular sleep-wakefulness schedule and the avoidance of sleep deprivation. |
2005-07-22 |
2023-08-12 |
Not clear |
| Carlos Eduardo Macedo, Raquel Chacon Ruiz Martinez, Maria Angélica de Souza Silva, Marcus Lira Brandã. Increases in extracellular levels of 5-HT and dopamine in the basolateral, but not in the central, nucleus of amygdala induced by aversive stimulation of the inferior colliculus. The European journal of neuroscience. vol 21. issue 4. 2005-05-16. PMID:15787718. |
increases in extracellular levels of 5-ht and dopamine in the basolateral, but not in the central, nucleus of amygdala induced by aversive stimulation of the inferior colliculus. |
2005-05-16 |
2023-08-12 |
rat |
| G F Molodtsov. [Changes in brain serotonin metabolism and [3H]-serotonin receptor binding during recall of conditioned passive avoidance in rats]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 54. issue 4. 2005-05-02. PMID:15481391. |
[changes in brain serotonin metabolism and [3h]-serotonin receptor binding during recall of conditioned passive avoidance in rats]. |
2005-05-02 |
2023-08-12 |
rat |
| G F Molodtsov. [Changes in brain serotonin metabolism and [3H]-serotonin receptor binding during recall of conditioned passive avoidance in rats]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 54. issue 4. 2005-05-02. PMID:15481391. |
the content of serotonin and its metabolite 5-hydroxyindoleacetic acid, monoamine oxidase activity, and [3h]-serotonin radioligand receptor binding were examined in the prefrontal cortex, striatum, amygdala, hippocampus and periaqueductal gray matter at different time after one-trial passive avoidance training of rats. |
2005-05-02 |
2023-08-12 |
rat |
| Gabor Oroszi, David Goldma. Alcoholism: genes and mechanisms. Pharmacogenomics. vol 5. issue 8. 2005-04-12. PMID:15584875. |
functional alleles that alter alcoholism-related intermediate phenotypes include common alcohol dehydrogenase 1b and aldehyde dehydrogenase 2 variants that cause the aversive flushing reaction; catechol-o-methyltransferase (comt) val158met leading to differences in three aspects of neurobiology: executive cognitive function, stress/anxiety response, and opioid function; opioid receptor micro1 (oprm1) asn40asp, which may serve as a gatekeeper molecule in the action of naltrexone, a drug used in alcoholism treatment; and httlpr, which alters serotonin transporter function and appears to affect stress response and anxiety/dysphoria, which are factors relevant to initial vulnerability, the process of addiction, and relapse. |
2005-04-12 |
2023-08-12 |
Not clear |
| Miguel A Díaz del Guante, Mauricio Rivas, Roberto A Prado-Alcalá, Gina L Quirart. Amnesia produced by pre-training infusion of serotonin into the substantia nigra. Neuroreport. vol 15. issue 16. 2005-03-14. PMID:15538188. |
pre-training injections of serotonin into the nigra of rats produced strong amnesia of an aversively-motivated task (inhibitory avoidance) compared to similar injections into the cerebral cortex and zona incerta. |
2005-03-14 |
2023-08-12 |
rat |
| Carlos Eduardo Macedo, Gabriel Cuadra, Victor Molina, Marcus L Brandã. Aversive stimulation of the inferior colliculus changes dopamine and serotonin extracellular levels in the frontal cortex: modulation by the basolateral nucleus of amygdala. Synapse (New York, N.Y.). vol 55. issue 1. 2005-02-17. PMID:15515004. |
aversive stimulation of the inferior colliculus changes dopamine and serotonin extracellular levels in the frontal cortex: modulation by the basolateral nucleus of amygdala. |
2005-02-17 |
2023-08-12 |
rat |
| Cheryl L Limebeer, Linda A Parker, Paul J Fletche. 5,7-dihydroxytryptamine lesions of the dorsal and median raphe nuclei interfere with lithium-induced conditioned gaping, but not conditioned taste avoidance, in rats. Behavioral neuroscience. vol 118. issue 6. 2005-02-14. PMID:15598147. |
these results parallel previous pharmacological findings indicating that reduction of serotonin activity interferes with conditioned gaping, but not conditioned taste avoidance. |
2005-02-14 |
2023-08-12 |
rat |
| L H J Eberhart, G Geldner, S Hörle, H Wul. [Prophylaxis and treatment of nausea and vomiting after outpatient ophthalmic surgery]. Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft. vol 101. issue 9. 2005-02-08. PMID:14999416. |
however, when general anesthesia is necessary avoidance of volatile anesthetics, nitrous oxide, and administration of 5-ht(3) antagonists is recommended. |
2005-02-08 |
2023-08-12 |
Not clear |
| Michael Y Chao, Hidetoshi Komatsu, Hana S Fukuto, Heather M Dionne, Anne C Har. Feeding status and serotonin rapidly and reversibly modulate a Caenorhabditis elegans chemosensory circuit. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 43. 2004-12-09. PMID:15492222. |
here, we show that both food and 5-ht signaling modulate chemosensory avoidance response of octanol in c. elegans, and that this modulation is both rapid and reversible. |
2004-12-09 |
2023-08-12 |
caenorhabditis_elegans |
| Vanessa de Paula Soares, Hélio Zangross. Involvement of 5-HT1A and 5-HT2 receptors of the dorsal periaqueductal gray in the regulation of the defensive behaviors generated by the elevated T-maze. Brain research bulletin. vol 64. issue 2. 2004-11-29. PMID:15342106. |
previous studies have shown that serotonin plays an inhibitory role in escape behavior induced by the aversive stimulation of the dorsal periaqueductal gray matter (dpag). |
2004-11-29 |
2023-08-12 |
rat |
| Vanessa de Paula Soares, Hélio Zangross. Involvement of 5-HT1A and 5-HT2 receptors of the dorsal periaqueductal gray in the regulation of the defensive behaviors generated by the elevated T-maze. Brain research bulletin. vol 64. issue 2. 2004-11-29. PMID:15342106. |
ketanserin and sdz ser 082, but not way-100635 antagonized the effect of serotonin in facilitating inhibitory avoidance. |
2004-11-29 |
2023-08-12 |
rat |
| Vanessa de Paula Soares, Hélio Zangross. Involvement of 5-HT1A and 5-HT2 receptors of the dorsal periaqueductal gray in the regulation of the defensive behaviors generated by the elevated T-maze. Brain research bulletin. vol 64. issue 2. 2004-11-29. PMID:15342106. |
the results indicate that serotonin in the dpag exerts a phasic regulatory control on inhibitory avoidance and escape behaviors in the elevated t-maze. |
2004-11-29 |
2023-08-12 |
rat |
| Arthur Tomie, Aidaluz D Tirado, Lung Yu, Larissa A Pohoreck. Pavlovian autoshaping procedures increase plasma corticosterone and levels of norepinephrine and serotonin in prefrontal cortex in rats. Behavioural brain research. vol 153. issue 1. 2004-09-27. PMID:15219711. |
enhanced corticosterone release can be induced by aversive stimulation or stressful situations, where it is often accompanied by higher levels of norepinephrine (ne) and serotonin (5-ht) in prefrontal cortex (pfc) but not in striatum (st). |
2004-09-27 |
2023-08-12 |
rat |
| Frederico G Graef. Serotonin, the periaqueductal gray and panic. Neuroscience and biobehavioral reviews. vol 28. issue 3. 2004-09-17. PMID:15225969. |
evidence with conflict tests in experimental animals indicates that 5-ht enhances anxiety, whereas results with aversive stimulation of the dorsal periaqueductal gray point to an anxiolytic role of 5-ht. |
2004-09-17 |
2023-08-12 |
human |