| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dina M Schardt, Susanne Erk, Corinna Nüsser, Markus M Nöthen, Sven Cichon, Marcella Rietschel, Jens Treutlein, Thomas Goschke, Henrik Walte. Volition diminishes genetically mediated amygdala hyperreactivity. NeuroImage. vol 53. issue 3. 2011-01-03. PMID:19969089. |
individuals carrying the short allele of a common polymorphism in the promoter region of the serotonin transporter gene (5-httlpr) exhibit heightened amygdala responses to passive stimulation with aversive emotional material. |
2011-01-03 |
2023-08-12 |
human |
| Olga A Kharchenko, Vera V Grinkevich, Olga V Vorobiova, Larisa N Grinkevic. Learning-induced lateralized activation of the MAPK/ERK cascade in identified neurons of the food-aversion network in the mollusk Helix lucorum. Neurobiology of learning and memory. vol 94. issue 2. 2010-12-13. PMID:20452447. |
in the mollusk helix lucorum, serotonin induces activation of mapk/erk in the central nervous system (cns) upon food aversion learning. |
2010-12-13 |
2023-08-12 |
Not clear |
| Molly J Crockett, Luke Clark, Marc D Hauser, Trevor W Robbin. Serotonin selectively influences moral judgment and behavior through effects on harm aversion. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 40. 2010-11-16. PMID:20876101. |
serotonin selectively influences moral judgment and behavior through effects on harm aversion. |
2010-11-16 |
2023-08-12 |
human |
| Molly J Crockett, Luke Clark, Marc D Hauser, Trevor W Robbin. Serotonin selectively influences moral judgment and behavior through effects on harm aversion. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 40. 2010-11-16. PMID:20876101. |
here, we show that the neurotransmitter serotonin directly alters both moral judgment and behavior through increasing subjects' aversion to personally harming others. |
2010-11-16 |
2023-08-12 |
human |
| Molly J Crockett, Luke Clark, Marc D Hauser, Trevor W Robbin. Serotonin selectively influences moral judgment and behavior through effects on harm aversion. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 40. 2010-11-16. PMID:20876101. |
together, these findings provide unique evidence that serotonin could promote prosocial behavior by enhancing harm aversion, a prosocial sentiment that directly affects both moral judgment and moral behavior. |
2010-11-16 |
2023-08-12 |
human |
| Alessandro Bartolomucci, Valeria Carola, Tiziana Pascucci, Stefano Puglisi-Allegra, Simona Cabib, Klaus-Peter Lesch, Stefano Parmigiani, Paola Palanza, Cornelius Gros. Increased vulnerability to psychosocial stress in heterozygous serotonin transporter knockout mice. Disease models & mechanisms. vol 3. issue 7-8. 2010-10-07. PMID:20371729. |
heterozygous 5-htt knockout mice exposed to high stress also showed significantly lower levels of serotonin turnover than wild-type littermates, selectively in the frontal cortex, which is a structure that is known to control fear and avoidance responses, and that is implicated in susceptibility to depression. |
2010-10-07 |
2023-08-12 |
mouse |
| Roger Luis Henschel Pobbe, Helio Zangross. The lateral habenula regulates defensive behaviors through changes in 5-HT-mediated neurotransmission in the dorsal periaqueductal gray matter. Neuroscience letters. vol 479. issue 2. 2010-09-27. PMID:20478359. |
while stimulation of 5-ht(1a) receptors selectively affects escape performance, 5-ht(2a/2c) receptors modulate both inhibitory avoidance and escape. |
2010-09-27 |
2023-08-12 |
rat |
| M S Man, J W Dalley, A C Robert. Opposing effects of 5,7-DHT infusions into the orbitofrontal cortex and amygdala on flexible responding. Cerebral cortex (New York, N.Y. : 1991). vol 20. issue 7. 2010-08-31. PMID:19903764. |
serotonin depletion can lead to exaggerated aversive processing and deficient response inhibition, effects that have been linked to serotonin's actions in the amygdala and orbitofrontal cortex (ofc), respectively. |
2010-08-31 |
2023-08-12 |
Not clear |
| Gareth Harris, Holly Mills, Rachel Wragg, Vera Hapiak, Michelle Castelletto, Amanda Korchnak, Richard W Komunieck. The monoaminergic modulation of sensory-mediated aversive responses in Caenorhabditis elegans requires glutamatergic/peptidergic cotransmission. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 23. 2010-08-24. PMID:20534837. |
food or serotonin sensitize the ashs and stimulate aversive responses through a pathway requiring the release of nlp-3-encoded neuropeptides from the ashs. |
2010-08-24 |
2023-08-12 |
caenorhabditis_elegans |
| Matthew W Hale, Christopher E Stamper, Daniel R Staub, Christopher A Lowr. Urocortin 2 increases c-Fos expression in serotonergic neurons projecting to the ventricular/periventricular system. Experimental neurology. vol 224. issue 1. 2010-06-28. PMID:20382145. |
serotonin plays an important role in the regulation of anxiety states and physiological responses to aversive stimuli. |
2010-06-28 |
2023-08-12 |
Not clear |
| G S Kranz, S Kasper, R Lanzenberge. Reward and the serotonergic system. Neuroscience. vol 166. issue 4. 2010-06-17. PMID:20109531. |
pharmacological studies using agonists and antagonists of serotonergic receptor subtypes and approaches investigating an increase or decrease of the extracellular level of serotonin offer strong evidence for a serotonergic mediation, ranging from aversion to pleasure. |
2010-06-17 |
2023-08-12 |
human |
| Ciara McCabe, Zevic Mishor, Philip J Cowen, Catherine J Harme. Diminished neural processing of aversive and rewarding stimuli during selective serotonin reuptake inhibitor treatment. Biological psychiatry. vol 67. issue 5. 2010-05-20. PMID:20034615. |
diminished neural processing of aversive and rewarding stimuli during selective serotonin reuptake inhibitor treatment. |
2010-05-20 |
2023-08-12 |
Not clear |
| Jermaine D Jones, F Scott Hall, George R Uhl, Anthony L Rile. Dopamine, norepinephrine and serotonin transporter gene deletions differentially alter cocaine-induced taste aversion. Pharmacology, biochemistry, and behavior. vol 94. issue 4. 2010-04-29. PMID:19969013. |
dopamine, norepinephrine and serotonin transporter gene deletions differentially alter cocaine-induced taste aversion. |
2010-04-29 |
2023-08-12 |
mouse |
| Jermaine D Jones, F Scott Hall, George R Uhl, Anthony L Rile. Dopamine, norepinephrine and serotonin transporter gene deletions differentially alter cocaine-induced taste aversion. Pharmacology, biochemistry, and behavior. vol 94. issue 4. 2010-04-29. PMID:19969013. |
monoamine transporter knockout mice have been useful in the study of many different aspects of cocaine effects relevant to human drug use and addiction, yet an assessment of the effects of deletion of the genes for the dopamine, norepinephrine and serotonin transporters (dat, net, and sert, respectively) on cocaine's aversive properties has yet to be performed (uhl et al., 2002). |
2010-04-29 |
2023-08-12 |
mouse |
| U Dannlowski, C Konrad, V Arolt, T Suslo. [Neurogenetics of emotional processes. Neuroimaging findings as endophenotypes for depression]. Der Nervenarzt. vol 81. issue 1. 2010-04-08. PMID:20013254. |
a recent study, reporting an association of the risk allele in a serotonin transporter polymorphism (5-httlpr) with increased amygdala responsiveness to aversive stimuli, stimulated the new research field of imaging genetics, which is characterized by the choice of neurobiological activity patterns as endophenotypes. |
2010-04-08 |
2023-08-12 |
Not clear |
| Avishek Adhikari, Mihir A Topiwala, Joshua A Gordo. Synchronized activity between the ventral hippocampus and the medial prefrontal cortex during anxiety. Neuron. vol 65. issue 2. 2010-03-09. PMID:20152131. |
increases in mpfc theta power predicted avoidance of the aversive compartments of each arena and were larger in serotonin 1a receptor knockout mice, a genetic model of increased anxiety-like behavior. |
2010-03-09 |
2023-08-12 |
mouse |
| J M Wheeler, C Reed, S Burkhart-Kasch, N Li, C L Cunningham, A Janowsky, F H Franken, K M Wiren, J G Hashimoto, A C Scibelli, T J Phillip. Genetically correlated effects of selective breeding for high and low methamphetamine consumption. Genes, brain, and behavior. vol 8. issue 8. 2010-02-10. PMID:19689456. |
genes differentially expressed in the drug-naï ve state, including slc6a4 (serotonin transporter), htr3a (serotonin receptor 3a), rela [nuclear factor kappab (nfkappab)] and fos (cfos), represent candidates whose expression levels may predict methamphetamine consumption and susceptibility to methamphetamine reward and aversion. |
2010-02-10 |
2023-08-12 |
mouse |
| Elin Elvander-Tottie, Therese M Eriksson, Johan Sandin, Sven Ove Ogre. 5-HT(1A) and NMDA receptors interact in the rat medial septum and modulate hippocampal-dependent spatial learning. Hippocampus. vol 19. issue 12. 2010-01-28. PMID:19309036. |
intraseptal infusion of the 5-ht(1a) receptor agonist (r)-8-oh-dpat (1 or 4 microg/rat) did not affect spatial learning in the water maze task but impaired emotional memory in the passive avoidance task at the higher dose tested (4 microg/rat). |
2010-01-28 |
2023-08-12 |
rat |
| Saori C Tanaka, Kazuhiro Shishida, Nicolas Schweighofer, Yasumasa Okamoto, Shigeto Yamawaki, Kenji Doy. Serotonin affects association of aversive outcomes to past actions. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 50. 2010-01-26. PMID:20016081. |
serotonin affects association of aversive outcomes to past actions. |
2010-01-26 |
2023-08-12 |
human |
| S O Ogren, S B Ross, A C Holm, L Bauman. 5-Hydroxytryptamine and avoidance performance in the rat. Antagonism of the acute effect of p-chloroamphetamine by zimelidine, an inhibitor of 5-hydroxytryptamine uptake. Neuroscience letters. vol 7. issue 4. 2009-12-16. PMID:19605135. |
5-hydroxytryptamine and avoidance performance in the rat. |
2009-12-16 |
2023-08-12 |
rat |