| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mattie Tops, Sascha Russo, Maarten A S Boksem, Don M Tucke. Serotonin: modulator of a drive to withdraw. Brain and cognition. vol 71. issue 3. 2009-12-09. PMID:19423206. |
one function suggested for serotonin systems is the avoidance of threat. |
2009-12-09 |
2023-08-12 |
human |
| Hirokazu Matsuzaki, Takeshi Izumi, Machiko Matsumoto, Hiroko Togashi, Taku Yamaguchi, Takayuki Yoshida, Masahiko Watanabe, Mitsuhiro Yoshiok. Early postnatal stress affects 5-HT1A receptor function in the medial prefrontal cortex in adult rats. European journal of pharmacology. vol 615. issue 1-3. 2009-11-10. PMID:19470384. |
therefore, aversive stress in the third week of the postnatal period attenuates 5-ht(1a) receptor function in the medial prefrontal cortex in adulthood and produces feedback inhibition of the raphe nuclei via postsynaptic 5-ht(1a) receptors. |
2009-11-10 |
2023-08-12 |
rat |
| Molly J Crockett, Luke Clark, Trevor W Robbin. Reconciling the role of serotonin in behavioral inhibition and aversion: acute tryptophan depletion abolishes punishment-induced inhibition in humans. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 38. 2009-10-09. PMID:19776285. |
reconciling the role of serotonin in behavioral inhibition and aversion: acute tryptophan depletion abolishes punishment-induced inhibition in humans. |
2009-10-09 |
2023-08-12 |
human |
| Molly J Crockett, Luke Clark, Trevor W Robbin. Reconciling the role of serotonin in behavioral inhibition and aversion: acute tryptophan depletion abolishes punishment-induced inhibition in humans. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 38. 2009-10-09. PMID:19776285. |
one influential hypothesis has implicated serotonin in aversive processing; another has proposed a more general role for serotonin in behavioral inhibition. |
2009-10-09 |
2023-08-12 |
human |
| Molly J Crockett, Luke Clark, Trevor W Robbin. Reconciling the role of serotonin in behavioral inhibition and aversion: acute tryptophan depletion abolishes punishment-induced inhibition in humans. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 38. 2009-10-09. PMID:19776285. |
here, we show that serotonin is critical for punishment-induced inhibition but not overall motor response inhibition or reporting aversive outcomes. |
2009-10-09 |
2023-08-12 |
human |
| Molly J Crockett, Luke Clark, Trevor W Robbin. Reconciling the role of serotonin in behavioral inhibition and aversion: acute tryptophan depletion abolishes punishment-induced inhibition in humans. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 38. 2009-10-09. PMID:19776285. |
we used acute tryptophan depletion to temporarily lower brain serotonin in healthy human volunteers as they completed a novel task designed to obtain separate measures of motor response inhibition, punishment-induced inhibition, and sensitivity to aversive outcomes. |
2009-10-09 |
2023-08-12 |
human |
| Molly J Crockett, Luke Clark, Trevor W Robbin. Reconciling the role of serotonin in behavioral inhibition and aversion: acute tryptophan depletion abolishes punishment-induced inhibition in humans. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 38. 2009-10-09. PMID:19776285. |
these findings extend and clarify previous research on the role of serotonin in aversive processing and behavioral inhibition and fit with current theorizing on the involvement of serotonin in predicting aversive outcomes. |
2009-10-09 |
2023-08-12 |
human |
| Jermaine D Jones, F Scott Hall, George R Uhl, Kenner Rice, Anthony L Rile. Differential involvement of the norepinephrine, serotonin and dopamine reuptake transporter proteins in cocaine-induced taste aversion. Pharmacology, biochemistry, and behavior. vol 93. issue 1. 2009-08-19. PMID:19376154. |
differential involvement of the norepinephrine, serotonin and dopamine reuptake transporter proteins in cocaine-induced taste aversion. |
2009-08-19 |
2023-08-12 |
Not clear |
| Jermaine D Jones, F Scott Hall, George R Uhl, Kenner Rice, Anthony L Rile. Differential involvement of the norepinephrine, serotonin and dopamine reuptake transporter proteins in cocaine-induced taste aversion. Pharmacology, biochemistry, and behavior. vol 93. issue 1. 2009-08-19. PMID:19376154. |
combined, the results of these investigations indicate little or no involvement of dopaminergic systems in cocaine's aversive effects while ne appears to contribute most substantially, with a possible modulatory involvement by serotonin. |
2009-08-19 |
2023-08-12 |
Not clear |
| André Tadić, Anja Victor, Omür Başkaya, Robert von Cube, Julia Hoch, Ioanna Kouti, Nina J Anicker, Wolfgang Höppner, Klaus Lieb, Norbert Dahme. Interaction between gene variants of the serotonin transporter promoter region (5-HTTLPR) and catechol O-methyltransferase (COMT) in borderline personality disorder. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 150B. issue 4. 2009-07-30. PMID:18756498. |
recently, an investigation in male healthy volunteers found gene-gene effects of the catechol-o-methyl-transferase (comt) low-activity (met(158)) and the low-expression allele of the deletion/insertion (short/long or s/l, respectively) polymorphism in the serotonin transporter-linked promoter region (5-httlpr) on the central processing of aversive stimuli. |
2009-07-30 |
2023-08-12 |
human |
| Ranji Cui, Katsuya Suemaru, Bingjin Li, Shuntaro Kohnomi, Hiroaki Arak. Tropisetron attenuates naloxone-induced place aversion in single-dose morphine-treated rats: role of alpha7 nicotinic receptors. European journal of pharmacology. vol 609. issue 1-3. 2009-07-13. PMID:19374878. |
in the present study, we studied the effect of tropisetron, an alpha7 nicotinic receptor agonist and 5-hydroxytryptamine 3 (5-ht(3)) receptor antagonist, on place aversion induced by naloxone in morphine-treated rats. |
2009-07-13 |
2023-08-12 |
rat |
| Adam Z Weitemier, Niall P Murph. Accumbal dopamine and serotonin activity throughout acquisition and expression of place conditioning: correlative relationships with preference and aversion. The European journal of neuroscience. vol 29. issue 5. 2009-06-09. PMID:19245370. |
accumbal dopamine and serotonin activity throughout acquisition and expression of place conditioning: correlative relationships with preference and aversion. |
2009-06-09 |
2023-08-12 |
mouse |
| Adam Z Weitemier, Niall P Murph. Accumbal dopamine and serotonin activity throughout acquisition and expression of place conditioning: correlative relationships with preference and aversion. The European journal of neuroscience. vol 29. issue 5. 2009-06-09. PMID:19245370. |
in contrast, avoidance of an aversively-paired stimulus (the opiate antagonist naloxone) was associated with enhanced extracellular da levels, and also the balance between da and 5-ht responses. |
2009-06-09 |
2023-08-12 |
mouse |
| T Petrásek, A Stuchlí. Serotonin-depleted rats are capable of learning in active place avoidance, a spatial task requiring cognitive coordination. Physiological research. vol 58. issue 2. 2009-06-05. PMID:19397387. |
the present study examined the effects of serotonin depletion with p-chlorophenylalanine on learning of rats in active place avoidance, a spatial task requiring allothetic mapping and cognitive coordination and highly dependent upon hippocampus. |
2009-06-05 |
2023-08-12 |
rat |
| T Petrásek, A Stuchlí. Serotonin-depleted rats are capable of learning in active place avoidance, a spatial task requiring cognitive coordination. Physiological research. vol 58. issue 2. 2009-06-05. PMID:19397387. |
serotonin depletion transiently increased locomotor activity in response to footshocks, but it did not change the avoidance efficiency measured by three spatial parameters. |
2009-06-05 |
2023-08-12 |
rat |
| S V Solntseva, v P Nikiti. [Neurochemical mechanisms of food aversion conditioning consolidation in snail Helix lucorum]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 94. issue 11. 2009-05-12. PMID:19140302. |
food aversion conditioning was absent in snails after applications of metiotepin, nonselective serotonin receptors antagonist, or after mk-801, nmda glutamate receptors antagonist. |
2009-05-12 |
2023-08-12 |
Not clear |
| Vanessa de Paula Soares, Hélio Zangross. Stimulation of 5-HT1A or 5-HT2A receptors in the ventrolateral periaqueductal gray causes anxiolytic-, but not panicolytic-like effect in rats. Behavioural brain research. vol 197. issue 1. 2009-04-10. PMID:18801389. |
our results showed that intra-vlpag injection of the endogenous agonist serotonin, the 5-ht1a/7 agonist 8-oh-dpat or 5-ht2a/2c agonist doi impaired the acquisition of inhibitory avoidance, without interfering with escape performance. |
2009-04-10 |
2023-08-12 |
rat |
| Oliver Stiedl, René F Jansen, Anton W Pieneman, Sven Ove Ogren, Michael Meye. Assessing aversive emotional states through the heart in mice: implications for cardiovascular dysregulation in affective disorders. Neuroscience and biobehavioral reviews. vol 33. issue 2. 2009-03-25. PMID:18824021. |
these studies included pharmacological and genetic interventions of brain systems implicated in aversive emotional states, the corticotropin-releasing factor (crf) system and the serotonin (5-ht)1a receptor. |
2009-03-25 |
2023-08-12 |
mouse |
| Karina Santos Gomes, Eduardo Ferreira de Carvalho-Netto, Kátia Cristina Da Silva Monte, Bruno Acco, Paulo José de Campos Nogueira, Ricardo Luiz Nunes-de-Souz. Contrasting effects of acute and chronic treatment with imipramine and fluoxetine on inhibitory avoidance and escape responses in mice exposed to the elevated T-maze. Brain research bulletin. vol 78. issue 6. 2009-03-13. PMID:19047015. |
injections for 15 consecutive days) treatment with imipramine or fluoxetine, non-selective and selective serotonin reuptake inhibitors, respectively, on inhibitory avoidance and escape tasks in the mouse etm. |
2009-03-13 |
2023-08-12 |
mouse |
| Karina Santos Gomes, Eduardo Ferreira de Carvalho-Netto, Kátia Cristina Da Silva Monte, Bruno Acco, Paulo José de Campos Nogueira, Ricardo Luiz Nunes-de-Souz. Contrasting effects of acute and chronic treatment with imipramine and fluoxetine on inhibitory avoidance and escape responses in mice exposed to the elevated T-maze. Brain research bulletin. vol 78. issue 6. 2009-03-13. PMID:19047015. |
with this selective serotonin reuptake inhibitor (ssri) produced an opposite effect, i.e., it impaired inhibitory avoidance acquisition and facilitated open arm withdrawal. |
2009-03-13 |
2023-08-12 |
mouse |