Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
E Gottlieb, S M Armour, M H Harris, C B Thompso. Mitochondrial membrane potential regulates matrix configuration and cytochrome c release during apoptosis. Cell death and differentiation. vol 10. issue 6. 2004-02-19. PMID:12761579. |
mitochondrial membrane potential regulates matrix configuration and cytochrome c release during apoptosis. |
2004-02-19 |
2023-08-12 |
Not clear |
E Gottlieb, S M Armour, M H Harris, C B Thompso. Mitochondrial membrane potential regulates matrix configuration and cytochrome c release during apoptosis. Cell death and differentiation. vol 10. issue 6. 2004-02-19. PMID:12761579. |
in this work we show that, at the onset of apoptosis, changes in mmp control matrix remodeling prior to cytochrome c release. |
2004-02-19 |
2023-08-12 |
Not clear |
E Gottlieb, S M Armour, M H Harris, C B Thompso. Mitochondrial membrane potential regulates matrix configuration and cytochrome c release during apoptosis. Cell death and differentiation. vol 10. issue 6. 2004-02-19. PMID:12761579. |
matrix remodeling to the condensed state results in cristal unfolding and exposes cytochrome c to the intermembrane space facilitating its release from the mitochondria during apoptosis. |
2004-02-19 |
2023-08-12 |
Not clear |
Michael Mauro, Andrey Zlatopolskiy, Thomas J Raife, Jeffrey Laurenc. Thienopyridine-linked thrombotic microangiopathy: association with endothelial cell apoptosis and activation of MAP kinase signalling cascades. British journal of haematology. vol 124. issue 2. 2004-02-11. PMID:14687031. |
as ticlopidine can disrupt production of extracellular matrix (ecm) components critical to microvascular endothelial cell (mvec) integrity in vitro, we explored the hypotheses that ticlopidine and ticlopidine-linked ttp plasmas induce mvec apoptosis in a manner similar to that of idiopathic ttp plasmas, and that ecm components and related mitogen-activated protein kinase (mapk) signalling cascades may be involved in this process. |
2004-02-11 |
2023-08-12 |
human |
Guy Rosne. [Anoikis--a specific form of programmed cell death]. Harefuah. vol 142. issue 12. 2004-02-10. PMID:14702756. |
apoptosis triggered by cell detachment from the extracellular matrix, which occurs during hepatocyte isolation, is a phenomenon termed "anoikis". |
2004-02-10 |
2023-08-12 |
human |
T M Camp, S C Tyagi, R M Senior, M R Hayden, S C Tyag. Gelatinase B(MMP-9) an apoptotic factor in diabetic transgenic mice. Diabetologia. vol 46. issue 10. 2004-01-30. PMID:12928773. |
although matrix metalloproteinase-9 (mmp-9) is specifically induced and apoptosis of endothelial cells is evidenced in diabetes mellitus, the mechanism of endocardial endothelial dysfunction in diabetes mellitus is not clear. |
2004-01-30 |
2023-08-12 |
mouse |
Yan-Nien Liu, Bean-Bu Kang, J H Che. Transcriptional regulation of human osteopontin promoter by C/EBPalpha and AML-1 in metastatic cancer cells. Oncogene. vol 23. issue 1. 2004-01-28. PMID:14712233. |
it also mediates neovascularization, inhibits apoptosis, and plays important roles in extracellular matrix remodeling and angiogenesis. |
2004-01-28 |
2023-08-12 |
human |
William J Murdoch, Michelle L Gottsc. Proteolytic mechanisms in the ovulatory folliculo-luteal transformation. Connective tissue research. vol 44. issue 1. 2004-01-22. PMID:12945804. |
tumor necrosis factor alpha progressively induces matrix metalloproteinase gene expression, apoptosis, and inflammatory necrosis. |
2004-01-22 |
2023-08-12 |
Not clear |
Robert Sidbury, Nicole Neuschler, Erin Neuschler, Ping Sun, Xiao-qi Wang, Richard Miller, Mark Tomai, Elena Puscasiu, Sajiv Gugneja, Amy S Palle. Topically applied imiquimod inhibits vascular tumor growth in vivo. The Journal of investigative dermatology. vol 121. issue 5. 2004-01-22. PMID:14708627. |
imiquimod-treated tumors showed decreased tumor cell proliferation, increased tumor apoptosis, and increased expression of tissue inhibitor of matrix metalloproteinase-1 with decreased activity of matrix metalloproteinase-9. |
2004-01-22 |
2023-08-12 |
mouse |
Yasuyoshi Miyata, Shigehiko Koga, Shigeru Kanda, Masaharu Nishikido, Tomayoshi Hayashi, Hiroshi Kanetak. Expression of cyclooxygenase-2 in renal cell carcinoma: correlation with tumor cell proliferation, apoptosis, angiogenesis, expression of matrix metalloproteinase-2, and survival. Clinical cancer research : an official journal of the American Association for Cancer Research. vol 9. issue 5. 2004-01-12. PMID:12738729. |
expression of cyclooxygenase-2 in renal cell carcinoma: correlation with tumor cell proliferation, apoptosis, angiogenesis, expression of matrix metalloproteinase-2, and survival. |
2004-01-12 |
2023-08-12 |
Not clear |
Kenn Holmbeck, Paolo Bianco, Kali Chrysovergis, Susan Yamada, Henning Birkedal-Hanse. MT1-MMP-dependent, apoptotic remodeling of unmineralized cartilage: a critical process in skeletal growth. The Journal of cell biology. vol 163. issue 3. 2004-01-12. PMID:14610065. |
membrane-type 1 matrix metalloproteinase (mt1-mmp)-dependent dissolution of unmineralized cartilages, coupled with apoptosis of nonhypertrophic chondrocytes, mediates remodeling of these cartilages into other tissues. |
2004-01-12 |
2023-08-12 |
Not clear |
Kenn Holmbeck, Paolo Bianco, Kali Chrysovergis, Susan Yamada, Henning Birkedal-Hanse. MT1-MMP-dependent, apoptotic remodeling of unmineralized cartilage: a critical process in skeletal growth. The Journal of cell biology. vol 163. issue 3. 2004-01-12. PMID:14610065. |
the coordinated apoptosis and matrix metalloproteinase-directed cartilage dissolution is akin to metamorphosis and may thus represent its evolutionary legacy in mammals. |
2004-01-12 |
2023-08-12 |
Not clear |
Sergey G Kuznetsov, Friederike Anton-Erxleben, Thomas C G Bosc. Epithelial interactions in Hydra: apoptosis in interspecies grafts is induced by detachment from the extracellular matrix. The Journal of experimental biology. vol 205. issue Pt 24. 2004-01-09. PMID:12432005. |
epithelial interactions in hydra: apoptosis in interspecies grafts is induced by detachment from the extracellular matrix. |
2004-01-09 |
2023-08-12 |
Not clear |
Sergey G Kuznetsov, Friederike Anton-Erxleben, Thomas C G Bosc. Epithelial interactions in Hydra: apoptosis in interspecies grafts is induced by detachment from the extracellular matrix. The Journal of experimental biology. vol 205. issue Pt 24. 2004-01-09. PMID:12432005. |
we therefore suggest that in interspecies grafts, apoptosis is induced by the detachment of epithelial cells from the extracellular matrix (anoikis) and not by a discriminative allorecognition system. |
2004-01-09 |
2023-08-12 |
Not clear |
R Tracy Ballock, Regis J O'Keef. Physiology and pathophysiology of the growth plate. Birth defects research. Part C, Embryo today : reviews. vol 69. issue 2. 2004-01-06. PMID:12955857. |
through a sequential process of cell proliferation, extracellular matrix synthesis, cellular hypertrophy, matrix mineralization, vascular invasion, and eventually apoptosis, the cartilage model is continually replaced by bone as length increases. |
2004-01-06 |
2023-08-12 |
human |
Ju Hong Jeon, Chai Wan Kim, Dong Myung Shin, Kyu il Kim, Sung Yup Cho, Joon Cheol Kwon, Kyung Ho Choi, Heun Soo Kang, In Gyu Ki. Differential incorporation of biotinylated polyamines by transglutaminase 2. FEBS letters. vol 534. issue 1-3. 2004-01-05. PMID:12527383. |
polyamine incorporation or cross-linking of proteins, post-translational modifications mediated by transglutaminase 2 (tgase 2), have been implicated in a variety of physiological functions including cell adhesion, extracellular matrix formation and apoptosis. |
2004-01-05 |
2023-08-12 |
Not clear |
Antonio Pacifico, Philip D Henr. Structural pathways and prevention of heart failure and sudden death. Journal of cardiovascular electrophysiology. vol 14. issue 7. 2004-01-05. PMID:12930259. |
the microscopic myocardial anatomy of scd is incompletely defined but may include prevalent changes of advanced myocardial disease, including cardiomyocyte hypertrophy, cardiomyocyte apoptosis, fibroblast hyperplasia, diffuse and focal matrix protein accumulation, and recruitment of inflammatory cells. |
2004-01-05 |
2023-08-12 |
Not clear |
C S Adams, I M Shapir. Mechanisms by which extracellular matrix components induce osteoblast apoptosis. Connective tissue research. vol 44 Suppl 1. 2004-01-05. PMID:12952203. |
mechanisms by which extracellular matrix components induce osteoblast apoptosis. |
2004-01-05 |
2023-08-12 |
Not clear |
C S Adams, I M Shapir. Mechanisms by which extracellular matrix components induce osteoblast apoptosis. Connective tissue research. vol 44 Suppl 1. 2004-01-05. PMID:12952203. |
the aim of the current investigation is to elucidate the mechanism by which these extracellular matrix components induce bone cell apoptosis. |
2004-01-05 |
2023-08-12 |
Not clear |
C S Adams, I M Shapir. Mechanisms by which extracellular matrix components induce osteoblast apoptosis. Connective tissue research. vol 44 Suppl 1. 2004-01-05. PMID:12952203. |
the observation that two such pathways exist lends strength to the notion that apoptosis is carefully regulated in bone and that signals from both matrix components act together to trigger the remodeling process. |
2004-01-05 |
2023-08-12 |
Not clear |