| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Amit Verma, Kapil Meht. Tissue transglutaminase-mediated chemoresistance in cancer cells. Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy. vol 10. issue 4-5. 2008-01-03. PMID:17662645. |
tg2 is the most diverse and ubiquitous member of the transglutaminase family of proteins that is implicated to play a role in apoptosis, wound healing, cell migration, cell attachment, cell growth, angiogenesis, and matrix assembly. |
2008-01-03 |
2023-08-12 |
Not clear |
| b' M Magaraggia, L Marigo, A Pagnan, G Jori, A Vison\\xc3\\xa. Porphyrin-photosensitized processes: their applications in the prevention of arterial restenosis. Cardiovascular & hematological agents in medicinal chemistry. vol 5. issue 4. 2008-01-03. PMID:17979690.' |
extension of these investigations to an in vivo rabbit model showed that znpc mainly accumulated in the media layer, where pdt induces the main damage through cellular depletion due to apoptosis of smc, changes in the extracellular matrix with generation of a barrier to cellular migration, and acceleration of re-endothelization. |
2008-01-03 |
2023-08-12 |
rabbit |
| Hye-Ryun Kang, Chun Geun Lee, Robert J Homer, Jack A Elia. Semaphorin 7A plays a critical role in TGF-beta1-induced pulmonary fibrosis. The Journal of experimental medicine. vol 204. issue 5. 2008-01-02. PMID:17485510. |
tgf-beta(1) stimulated sema 7a via a largely smad 3-independent mechanism and stimulated sema 7a receptors, matrix proteins, ccn proteins, fibroblast growth factor 2, interleukin 13 receptor components, proteases, antiprotease, and apoptosis regulators via smad 2/3-independent and sema 7a-dependent mechanisms. |
2008-01-02 |
2023-08-12 |
Not clear |
| Sahin Coban, Osman Yüksel, Muhammed Cem Koçkar, Seyfettin Köklü, Omer Basar, Hüseyin Tutkak, Necati Ormec. The significance of serum transforming growth factor beta 1 in detecting of gastric and colon cancers. Hepato-gastroenterology. vol 54. issue 77. 2007-12-27. PMID:17708279. |
tgf-beta1 is a growth factor with wide ranging effects on proliferation, differentiation, immune suppression, apoptosis and matrix remodeling. |
2007-12-27 |
2023-08-12 |
Not clear |
| Gretchen A Repasky, Yixing Zhou, Staeci Morita, Channing J De. Ras-mediated intestinal epithelial cell transformation requires cyclooxygenase-2-induced prostaglandin E2 signaling. Molecular carcinogenesis. vol 46. issue 12. 2007-12-20. PMID:17477350. |
finally, we found that pge2 stimulated the activation of ras and erk, but not akt, and reduced matrix deprivation-induced apoptosis, in untransformed epithelial cells. |
2007-12-20 |
2023-08-12 |
Not clear |
| Alex Y Hui, Scott L Friedma. Molecular basis of hepatic fibrosis. Expert reviews in molecular medicine. vol 5. issue 5. 2007-12-18. PMID:14987408. |
major advances include: (1) elucidation of the effects (and signalling pathways) of key cytokines on hscs; (2) understanding the transcriptional regulation of hsc activation; (3) characterisation of matrix proteases and their inhibitors; (4) demonstration of apoptosis as an important event in the resolution of hepatic fibrosis, and identification of its mediators;(5) elucidation of the complex and dynamic interaction between hscs and matrix; and (6) understanding the role of other cellular elements in hepatic fibrosis and their interaction with hscs. |
2007-12-18 |
2023-08-12 |
Not clear |
| William Macne. Pathogenesis of chronic obstructive pulmonary disease. Clinics in chest medicine. vol 28. issue 3. 2007-12-18. PMID:17720039. |
other processes, such as failure to resolve inflammation, abnormal cell repair, apoptosis, abnormal cellular maintenance programs, extracellular matrix destruction (protease/antiprotease imbalance), and oxidative stress (oxidant/antioxidant imbalance) also have a role. |
2007-12-18 |
2023-08-12 |
Not clear |
| Mei G Sun, James Williams, Cristina Munoz-Pinedo, Guy A Perkins, Joshua M Brown, Mark H Ellisman, Douglas R Green, Terrence G Fre. Correlated three-dimensional light and electron microscopy reveals transformation of mitochondria during apoptosis. Nature cell biology. vol 9. issue 9. 2007-12-17. PMID:17721514. |
we have identified a remodelling of the inner mitochondrial membrane into many separate vesicular matrix compartments that accompanies release of proteins; however, this remodelling is not required for efficient release of cytochrome c. swelling occurs only late in apoptosis after release of cytochrome c and loss of the mitochondrial membrane potential. |
2007-12-17 |
2023-08-12 |
Not clear |
| E Zeldich, R Koren, M Dard, C Nemcovsky, M Weinre. Enamel matrix derivative protects human gingival fibroblasts from TNF-induced apoptosis by inhibiting caspase activation. Journal of cellular physiology. vol 213. issue 3. 2007-12-14. PMID:17607712. |
enamel matrix derivative protects human gingival fibroblasts from tnf-induced apoptosis by inhibiting caspase activation. |
2007-12-14 |
2023-08-12 |
human |
| D Eberli, R Susaeta, J J Yoo, A Atal. Tunica repair with acellular bladder matrix maintains corporal tissue function. International journal of impotence research. vol 19. issue 6. 2007-12-07. PMID:17673933. |
biocompatibility testing was performed on the matrix, which included mitochondrial metabolic activity, cell viability and apoptosis. |
2007-12-07 |
2023-08-12 |
Not clear |
| Andrea Telek, Tamás Bíró, Eniko Bodó, Balázs I Tóth, István Borbíró, George Kunos, Ralf Pau. Inhibition of human hair follicle growth by endo- and exocannabinoids. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 21. issue 13. 2007-12-03. PMID:17567570. |
namely, the endocannabinoid n-arachidonoylethanolamide (anandamide, aea) as well as the exocannabinnoid delta (9) -tetrahydrocannabinol dose-dependently inhibited hair shaft elongation and the proliferation of hair matrix keratinocytes, and induced intraepithelial apoptosis and premature hf regression (catagen). |
2007-12-03 |
2023-08-12 |
human |
| Nicholas T Woods, Hirohito Yamaguchi, Francis Y Lee, Kapil N Bhalla, Hong-Gang Wan. Anoikis, initiated by Mcl-1 degradation and Bim induction, is deregulated during oncogenesis. Cancer research. vol 67. issue 22. 2007-12-03. PMID:18006817. |
anoikis, a bax-dependent apoptosis triggered by detachment from the extracellular matrix, is often dysfunctional in metastatic cancer cells. |
2007-12-03 |
2023-08-12 |
Not clear |
| D J Scott, A T Parkes, F Ponchel, M Cummings, I Poola, V Speir. Changes in expression of steroid receptors, their downstream target genes and their associated co-regulators during the sequential acquisition of tamoxifen resistance in vitro. International journal of oncology. vol 31. issue 3. 2007-11-30. PMID:17671682. |
in addition, genes associated with cell cycle, cell adhesion and extracellular matrix, were up-regulated while those associated with apoptosis or growth factors/hormones were down-regulated. |
2007-11-30 |
2023-08-12 |
Not clear |
| Takashi Hasebe, Mitsuko Kajita, Kenta Fujimoto, Yoshio Yaoita, Atsuko Ishizuya-Ok. Expression profiles of the duplicated matrix metalloproteinase-9 genes suggest their different roles in apoptosis of larval intestinal epithelial cells during Xenopus laevis metamorphosis. Developmental dynamics : an official publication of the American Association of Anatomists. vol 236. issue 8. 2007-11-28. PMID:17654707. |
expression profiles of the duplicated matrix metalloproteinase-9 genes suggest their different roles in apoptosis of larval intestinal epithelial cells during xenopus laevis metamorphosis. |
2007-11-28 |
2023-08-12 |
xenopus_laevis |
| Eniko Bodó, Desmond J Tobin, York Kamenisch, Tamás Bíró, Mark Berneburg, Wolfgang Funk, Ralf Pau. Dissecting the impact of chemotherapy on the human hair follicle: a pragmatic in vitro assay for studying the pathogenesis and potential management of hair follicle dystrophy. The American journal of pathology. vol 171. issue 4. 2007-11-26. PMID:17823286. |
here, we show that these organ-cultured hfs respond to a key cyclophosphamide metabolite, 4-hydroperoxycyclophosphamide (4-hc), in a manner that resembles chemotherapy-induced hf dystrophy as it occurs in vivo: namely, 4-hc induced melanin clumping and melanin incontinence, down-regulated keratinocyte proliferation, massively up-regulated apoptosis of hair matrix keratinocytes, prematurely induced catagen, and up-regulated p53. |
2007-11-26 |
2023-08-12 |
human |
| Srikumar Sengupta, Johan A den Boon, I-How Chen, Michael A Newton, David B Dahl, Meng Chen, Yu-Juen Cheng, William H Westra, Chien-Jen Chen, Allan Hildesheim, Bill Sugden, Paul Ahlquis. Genome-wide expression profiling reveals EBV-associated inhibition of MHC class I expression in nasopharyngeal carcinoma. Cancer research. vol 66. issue 16. 2007-11-13. PMID:16912175. |
our data clearly reflect such tumor promotion, showing that deregulation of key proteins involved in apoptosis (bcl2-related protein a1 and fas apoptotic inhibitory molecule), cell cycle checkpoints (akip, scyl1, and nin), and metastasis (matrix metalloproteinase 1) is closely correlated with the levels of ebv gene expression in npc. |
2007-11-13 |
2023-08-12 |
human |
| K Edamura, Y Nasu, M Takaishi, T Kobayashi, F Abarzua, M Sakaguchi, Y Kashiwakura, S Ebara, T Saika, M Watanabe, N-H Huh, H Kumo. Adenovirus-mediated REIC/Dkk-3 gene transfer inhibits tumor growth and metastasis in an orthotopic prostate cancer model. Cancer gene therapy. vol 14. issue 9. 2007-11-13. PMID:17599093. |
these therapeutic responses were consistent with the intratumoral apoptosis induction and in vitro suppression of cell invasion/migration with reduced matrix metalloprotease-2 activity. |
2007-11-13 |
2023-08-12 |
mouse |
| Anja Sachse, Gunter Wol. Angiotensin II-induced reactive oxygen species and the kidney. Journal of the American Society of Nephrology : JASN. vol 18. issue 9. 2007-11-13. PMID:17687073. |
they are transducers of cell growth, apoptosis, and cell migration and affect expression of inflammatory and extracellular matrix genes. |
2007-11-13 |
2023-08-12 |
human |
| Sashwati Roy, Savita Khanna, Donald E Kuhn, Cameron Rink, Willis T Williams, Jay L Zweier, Chandan K Se. Transcriptome analysis of the ischemia-reperfused remodeling myocardium: temporal changes in inflammation and extracellular matrix. Physiological genomics. vol 25. issue 3. 2007-11-08. PMID:16554547. |
the candidate genes represented three major functional categories: extracellular matrix, apoptosis, and inflammation. |
2007-11-08 |
2023-08-12 |
rat |
| Kate D Sutherland, Geoffrey J Lindeman, Jane E Visvade. The molecular culprits underlying precocious mammary gland involution. Journal of mammary gland biology and neoplasia. vol 12. issue 1. 2007-11-08. PMID:17323120. |
over the past few years, significant advances have been made in understanding the signaling pathways and downstream effectors that regulate epithelial cell apoptosis in the first phase of involution, and the importance of matrix metalloproteinases and their inhibitors in both phases of involution. |
2007-11-08 |
2023-08-12 |
mouse |