| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christopher J Carbone, Xavier Graña, E Premkumar Reddy, Dale S Haine. p21 loss cooperates with INK4 inactivation facilitating immortalization and Bcl-2-mediated anchorage-independent growth of oncogene-transduced primary mouse fibroblasts. Cancer research. vol 67. issue 9. 2007-06-18. PMID:17483323. |
in addition, absence of prb function renders h-ras(v12) + c-myc-transduced fibroblasts prone to apoptosis when deprived of the extracellular matrix, and oncogene-induced anchorage-independent growth of pocket protein-deficient cells requires apoptotic suppression. |
2007-06-18 |
2023-08-12 |
mouse |
| Sudhiranjan Gupta, Biswajit Das, Subha Se. Cardiac hypertrophy: mechanisms and therapeutic opportunities. Antioxidants & redox signaling. vol 9. issue 6. 2007-06-18. PMID:17511580. |
many factors have been implicated in cardiac remodeling, including alterations in gene expression in myocytes, cardiomyocytes apoptosis, cytokines and growth factors that influence cardiac dynamics, and deficits in energy metabolism as well as alterations in cardiac extracellular matrix composition. |
2007-06-18 |
2023-08-12 |
Not clear |
| Ravi Dhurjati, Xiaomei Liu, Carol V Gay, Andrea M Mastro, Erwin A Vogle. Extended-term culture of bone cells in a compartmentalized bioreactor. Tissue engineering. vol 12. issue 11. 2007-06-18. PMID:17518620. |
cells in the bioreactor basically matched results obtained in tcps over a 15-day culture interval, but loss of insoluble extracellular matrix and an approximate doubling of apoptosis rates in tcps after 30 days indicated that progressive instability of cultures maintained in tcps with periodic refeeding but without subculture. |
2007-06-18 |
2023-08-12 |
mouse |
| Thomas Effert. Willmar Schwabe Award 2006: antiplasmodial and antitumor activity of artemisinin--from bench to bedside. Planta medica. vol 73. issue 4. 2007-06-14. PMID:17354163. |
the identified genes are from classes with diverse biological functions; for example, regulation of proliferation (bub3, cyclins, cdc25a), angiogenesis (vascular endothelial growth factor and its receptor, matrix metalloproteinase-9, angiostatin, thrombospondin-1) or apoptosis (bcl-2, bax, nf-kappab). |
2007-06-14 |
2023-08-12 |
mouse |
| b' Iva Orli\\xc4\\x87, Fran Borovecki, Petra Simi\\xc4\\x87, Slobodan Vukicevi\\xc4\\x8. Gene expression profiling in bone tissue of osteoporotic mice. Arhiv za higijenu rada i toksikologiju. vol 58. issue 1. 2007-06-12. PMID:17424779.' |
following ovx, genes involved in immune response, cell cycle regulation, growth, apoptosis and bone resorption were upregulated, while genes that are important for regular cell processes, mitosis, metabolism of carbohydrates, extracellular matrix structure, angiogenesis, skeletal development and morphogenesis were downregulated. |
2007-06-12 |
2023-08-12 |
mouse |
| Francisco García-Esteo, Gemma Pascual, Alberto Gallardo, Julio San-Román, Julia Buján, Juan Manuel Belló. A biodegradable copolymer for the slow release of growth hormone expedites scarring in diabetic rats. Journal of biomedical materials research. Part B, Applied biomaterials. vol 81. issue 2. 2007-06-11. PMID:16969827. |
our findings indicate that gh induces cell proliferation, enhances cd4(+) infiltration; increases extracellular matrix protein deposition; stimulates angiogenesis; and diminishes apoptosis at the diabetic wound site. |
2007-06-11 |
2023-08-12 |
rat |
| Giacomo Finocchiaro, Francesco Mattia Mancuso, Davide Cittaro, Heiko Mulle. Graph-based identification of cancer signaling pathways from published gene expression signatures using PubLiME. Nucleic acids research. vol 35. issue 7. 2007-06-05. PMID:17389643. |
the identified communities consist of cell cycle, apoptosis, phosphorylation cascade, extra cellular matrix, interferon and immune response regulators as well as communities of unknown function. |
2007-06-05 |
2023-08-12 |
Not clear |
| Masaki Fujita, Yoichi Nakanish. The pathogenesis of COPD: lessons learned from in vivo animal models. Medical science monitor : international medical journal of experimental and clinical research. vol 13. issue 2. 2007-05-31. PMID:17261992. |
several important factors such as matrix metalloproteinases, apoptosis, protease-antiprotease imbalance, are considered to contribute to the development of copd. |
2007-05-31 |
2023-08-12 |
Not clear |
| M L Bowie, M M Troch, J Delrow, E C Dietze, G R Bean, C Ibarra, G Pandiyan, V L Seewald. Interferon regulatory factor-1 regulates reconstituted extracellular matrix (rECM)-mediated apoptosis in human mammary epithelial cells. Oncogene. vol 26. issue 14. 2007-05-23. PMID:17016442. |
interferon regulatory factor-1 regulates reconstituted extracellular matrix (recm)-mediated apoptosis in human mammary epithelial cells. |
2007-05-23 |
2023-08-12 |
human |
| J-P Upton, A J Valentijn, L Zhang, A P Gilmor. The N-terminal conformation of Bax regulates cell commitment to apoptosis. Cell death and differentiation. vol 14. issue 5. 2007-05-23. PMID:17273174. |
using anoikis as a model, we have shown that bax translocation does not commit cells to apoptosis, and they can be rescued by reattachment to extracellular matrix within a specific time. |
2007-05-23 |
2023-08-12 |
Not clear |
| Ajaikumar B Kunnumakkara, Sushovan Guha, Sunil Krishnan, Parmeswaran Diagaradjane, Juri Gelovani, Bharat B Aggarwa. Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappaB-regulated gene products. Cancer research. vol 67. issue 8. 2007-05-23. PMID:17440100. |
in vivo, tumors from nude mice injected with pancreatic cancer cells and treated with a combination of curcumin and gemcitabine showed significant reductions in volume (p = 0.008 versus control; p = 0.036 versus gemcitabine alone), ki-67 proliferation index (p = 0.030 versus control), nf-kappab activation, and expression of nf-kappab-regulated gene products (cyclin d1, c-myc, bcl-2, bcl-xl, cellular inhibitor of apoptosis protein-1, cyclooxygenase-2, matrix metalloproteinase, and vascular endothelial growth factor) compared with tumors from control mice treated with olive oil only. |
2007-05-23 |
2023-08-12 |
mouse |
| Peter V N Bodine, Barry S Kom. Wnt signaling and osteoblastogenesis. Reviews in endocrine & metabolic disorders. vol 7. issue 1-2. 2007-05-22. PMID:16960757. |
studies of knockout and transgenic mouse models for wnt pathway components like wnt-10b, lrp-5/6, secreted frizzled-related protein-1, dickkopf-2, axin-2 and beta-catenin have demonstrated that canonical signaling modulates most aspects of osteoblast physiology including proliferation, differentiation, bone matrix formation/mineralization and apoptosis as well as coupling to osteoclastogenesis and bone resorption. |
2007-05-22 |
2023-08-12 |
mouse |
| R Zaragozá, A Gimeno, V J Miralles, E R García-Trevijano, R Carmena, C García, M Mata, I R Puertes, L Torres, J R Viñ. Retinoids induce MMP-9 expression through RARalpha during mammary gland remodeling. American journal of physiology. Endocrinology and metabolism. vol 292. issue 4. 2007-05-21. PMID:17164434. |
the aim of this paper was to study the role of ra during weaning, which consists of three events: apoptosis of the secretory cells, degradation of the extracellular matrix, and adipogenesis. |
2007-05-21 |
2023-08-12 |
rat |
| T John, P F Stahel, S J Morgan, G Schulze-Tanzi. Impact of the complement cascade on posttraumatic cartilage inflammation and degradation. Histology and histopathology. vol 22. issue 7. 2007-05-17. PMID:17455152. |
the local inflammatory response contributes to the pathogenesis of osteoarthritis by inducing chondrocyte apoptosis and the de-regulation of chondrocyte matrix remodelling. |
2007-05-17 |
2023-08-12 |
Not clear |
| Oxana Ibraghimov-Beskrovnaya, Nikolay O Bukano. In vitro cystogenesis: the search for drugs antagonizing cyst development. Nephrologie & therapeutique. vol 2 Suppl 2. 2007-05-14. PMID:17373209. |
autosomal dominant polycystic kidney disease (adpkd) cystogenesis has been extensively studied and major characteristic abnormalities were identified including increased proliferation, apoptosis, changes in cellular polarity, abnormal matrix composition and fluid secretion. |
2007-05-14 |
2023-08-12 |
Not clear |
| Wa Xian, Kathryn L Schwertfeger, Jeffrey M Rose. Distinct roles of fibroblast growth factor receptor 1 and 2 in regulating cell survival and epithelial-mesenchymal transition. Molecular endocrinology (Baltimore, Md.). vol 21. issue 4. 2007-05-07. PMID:17284663. |
in contrast, ifgfr2 activation induced cell apoptosis even in the cells in direct contact with the extracellular matrix. |
2007-05-07 |
2023-08-12 |
mouse |
| Pier Paolo Piccaluga, Claudio Agostinelli, Andrea Califano, Maura Rossi, Katia Basso, Simonetta Zupo, Philip Went, Ulf Klein, Pier Luigi Zinzani, Michele Baccarani, Riccardo Dalla Favera, Stefano A Piler. Gene expression analysis of peripheral T cell lymphoma, unspecified, reveals distinct profiles and new potential therapeutic targets. The Journal of clinical investigation. vol 117. issue 3. 2007-05-04. PMID:17304354. |
when compared with normal t cells, ptcls/u display deregulation of functional programs often involved in tumorigenesis (e.g., apoptosis, proliferation, cell adhesion, and matrix remodeling). |
2007-05-04 |
2023-08-12 |
Not clear |
| Muhammad G Kibriya, Farzana Jasmine, Maria Argos, Wendy J Verret, Muhammad Rakibuz-Zaman, Alauddin Ahmed, Faruque Parvez, Habibul Ahsa. Changes in gene expression profiles in response to selenium supplementation among individuals with arsenic-induced pre-malignant skin lesions. Toxicology letters. vol 169. issue 2. 2007-05-03. PMID:17293063. |
when mapped to a biological association network, many of the differentially expressed genes were found to regulate functional classes such as fibroblast growth factor, collagenase, matrix metalloproteinase and stromelysin-1, and thus, considered to affect cellular processes like apoptosis, proliferation and others. |
2007-05-03 |
2023-08-12 |
human |
| Tobias Schmelzle, Arnaud A Mailleux, Michael Overholtzer, Jason S Carroll, Nicole L Solimini, Eric S Lightcap, Ole P Veiby, Joan S Brugg. Functional role and oncogene-regulated expression of the BH3-only factor Bmf in mammary epithelial anoikis and morphogenesis. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 10. 2007-04-24. PMID:17360431. |
the formation of a lumen in three-dimensional mammary epithelial acinar structures in vitro involves selective apoptosis of centrally localized cells that lack matrix attachment. |
2007-04-24 |
2023-08-12 |
mouse |
| Tobias Schmelzle, Arnaud A Mailleux, Michael Overholtzer, Jason S Carroll, Nicole L Solimini, Eric S Lightcap, Ole P Veiby, Joan S Brugg. Functional role and oncogene-regulated expression of the BH3-only factor Bmf in mammary epithelial anoikis and morphogenesis. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 10. 2007-04-24. PMID:17360431. |
similarly, apoptosis is induced by forced detachment of mammary epithelial cells from matrix, a process referred to as anoikis. |
2007-04-24 |
2023-08-12 |
mouse |