| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mark A Carlson, Amy K Prall, Jeremiah J Gums, Alex Lesiak, Valerie K Shostro. Biologic variability of human foreskin fibroblasts in 2D and 3D culture: implications for a wound healing model. BMC research notes. vol 2. 2009-12-16. PMID:19922655. |
it was hypothesized that anchorage disruption of the collagen matrix would produce p53-dependent apoptosis in the embedded fibroblasts, but results of hypothesis testing were variant. |
2009-12-16 |
2023-08-12 |
human |
| L Lahtinen, N Huusko, H Myöhänen, A-K Lehtivarjo, R Pellinen, M P Turunen, S Ylä-Herttuala, E Pirinen, A Pitkäne. Expression of urokinase-type plasminogen activator receptor is increased during epileptogenesis in the rat hippocampus. Neuroscience. vol 163. issue 1. 2009-12-15. PMID:19527776. |
urokinase-type plasminogen activator receptor (upar) is functionally a pleiotropic mediator involved in cell adhesion, proliferation, differentiation and migration as well as in matrix degradation, apoptosis, and angiogenesis in cancer tissue. |
2009-12-15 |
2023-08-12 |
rat |
| S M Coope. A perspective on the use of minocycline for rheumatoid arthritis. Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases. vol 5. issue 4. 2009-12-14. PMID:19078393. |
laboratory investigations that support a possible anti-arthritic action of tetracyclines through their effect on nitric oxide generation, matrix metalloprotease inhibition, and chondrocyte apoptosis are discussed. |
2009-12-14 |
2023-08-12 |
Not clear |
| Li Wan. [Resistance of leukemia cells to Fas/FasL-mediated apoptosis and strategies replying to antiapoptosis of leukemia cells--review]. Zhongguo shi yan xue ye xue za zhi. vol 15. issue 6. 2009-12-11. PMID:18088494. |
in recent years studies related to mechanisms of leukemia cell resistance to fas/fasl-mediated apoptosis such as fas and fasl mutation and expression abnormality, fas signaling transduction pathway abnormality, and regulatory affect of apoptotic regulatory genes on fas/fasl system, as well as strategies replying to antiapoptosis of leukemia cells including nf-kappab, xiap, membrane receptor cd28 and matrix metalloproteinase 7 obtained some progresses. |
2009-12-11 |
2023-08-12 |
Not clear |
| Karen L Posey, Alka C Veerisetty, Pieman Liu, Huiqiu R Wang, Brian J Poindexter, Roger Bick, Joseph L Alcorn, Jacqueline T Hech. An inducible cartilage oligomeric matrix protein mouse model recapitulates human pseudoachondroplasia phenotype. The American journal of pathology. vol 175. issue 4. 2009-12-09. PMID:19762713. |
in contrast, the structure of the mt-comp growth plate recapitulated the findings of human psach growth plate morphology, including (1) retention of ecm proteins, (2) intracellular matrix formation in the rer cisternae, and (3) increased chondrocyte apoptosis. |
2009-12-09 |
2023-08-12 |
mouse |
| Carrie A Franzen, Chih-Chiun Chen, Viktor Todorović, Vladislava Juric, Ricardo I Monzon, Lester F La. Matrix protein CCN1 is critical for prostate carcinoma cell proliferation and TRAIL-induced apoptosis. Molecular cancer research : MCR. vol 7. issue 7. 2009-12-03. PMID:19584265. |
matrix protein ccn1 is critical for prostate carcinoma cell proliferation and trail-induced apoptosis. |
2009-12-03 |
2023-08-12 |
Not clear |
| Jesus Munoz, Yanwen Zhou, Harry W Jarret. LG4-5 domains of laminin-211 binds alpha-dystroglycan to allow myotube attachment and prevent anoikis. Journal of cellular physiology. vol 222. issue 1. 2009-11-23. PMID:19739104. |
incorporation of merosin (laminin-211) or the short laminin globular (lg4-5) modules of the laminin-alpha2 chain c-terminus (called 2e3) that binds alpha-dystroglycan diminishes both apoptosis and necrosis and increases viability while bovine serum albumin had a much lesser effect, showing the specificity of this effect for these matrix proteins. |
2009-11-23 |
2023-08-12 |
mouse |
| Antti Saraste, Stephan G Nekolla, Markus Schwaige. Cardiovascular molecular imaging: an overview. Cardiovascular research. vol 83. issue 4. 2009-11-16. PMID:19553359. |
imaging probes detecting myocardial apoptosis, metabolic alterations, injury to extracellular matrix, angiogenesis, or innervation may provide tools for assessing risk of arrhythmias and left ventricular remodelling associated with progressive cardiac dysfunction and heart failure. |
2009-11-16 |
2023-08-12 |
Not clear |
| Héloïse P Gaide Chevronnay, Christine Galant, Pascale Lemoine, Pierre J Courtoy, Etienne Marbaix, Patrick Henrie. Spatiotemporal coupling of focal extracellular matrix degradation and reconstruction in the menstrual human endometrium. Endocrinology. vol 150. issue 11. 2009-11-16. PMID:19819954. |
strikingly, in addition to genes products associated with tissue degradation (matrix metalloproteinase and plasmin systems) and apoptosis, superficial lysed stroma was enriched in gene products associated with ecm biosynthesis (collagens and their processing enzymes). |
2009-11-16 |
2023-08-12 |
mouse |
| Ritsuko Nakano-Kurimoto, Koji Ikeda, Maki Uraoka, Yusuke Nakagawa, Kotaro Yutaka, Masahiro Koide, Tomosaburo Takahashi, Satoaki Matoba, Hiroyuki Yamada, Mitsuhiko Okigaki, Hiroaki Matsubar. Replicative senescence of vascular smooth muscle cells enhances the calcification through initiating the osteoblastic transition. American journal of physiology. Heart and circulatory physiology. vol 297. issue 5. 2009-11-12. PMID:19749165. |
we also found that statin and rho-kinase inhibitor effectively reduced the vsmc calcification by inhibiting p(i)-induced apoptosis and potentially enhancing matrix gla protein expression in the senescent vsmcs. |
2009-11-12 |
2023-08-12 |
mouse |
| Jorge I Alvarez, Janani Krishnamurthy, Judy M Teal. Doxycycline treatment decreases morbidity and mortality of murine neurocysticercosis: evidence for reduction of apoptosis and matrix metalloproteinase activity. The American journal of pathology. vol 175. issue 2. 2009-10-27. PMID:19574432. |
doxycycline treatment decreases morbidity and mortality of murine neurocysticercosis: evidence for reduction of apoptosis and matrix metalloproteinase activity. |
2009-10-27 |
2023-08-12 |
Not clear |
| Guadalupe Ortiz-Muñoz, Xavier Houard, Jose-Luis Martín-Ventura, Brian Y Ishida, Stéphane Loyau, Patrick Rossignol, Juan-Antonio Moreno, John P Kane, Robert J Chalkley, Alma L Burlingame, Jean-Baptiste Michel, Olivier Meilha. HDL antielastase activity prevents smooth muscle cell anoikis, a potential new antiatherogenic property. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 23. issue 9. 2009-10-23. PMID:19417089. |
hdl-associated aat was able to inhibit extracellular matrix degradation, cell detachment, and apoptosis induced by elastase in human vascular smooth muscle cells (vsmcs) and in mammary artery cultured ex vivo. |
2009-10-23 |
2023-08-12 |
human |
| Yu-Ping Lin, Chung-Chen Su, Jyun-Yuan Huang, Huan-Chin Lin, Yu-Jung Cheng, Ming-Fei Liu, Bei-Chang Yan. Aberrant integrin activation induces p38 MAPK phosphorylation resulting in suppressed Fas-mediated apoptosis in T cells: implications for rheumatoid arthritis. Molecular immunology. vol 46. issue 16. 2009-10-20. PMID:19698994. |
exposure to ra synovial fluid or soluble collagen, a degradation product of extracellular matrix abundant in ra synovium, induced the phosphorylation of p38 mapk in jurkat t cells accompanied by resistance against fas-mediated apoptosis. |
2009-10-20 |
2023-08-12 |
Not clear |
| Dennis R Warner, Henry S Smith, Cynthia L Webb, Robert M Greene, M Michele Pisan. Expression of Wnts in the developing murine secondary palate. The International journal of developmental biology. vol 53. issue 7. 2009-10-19. PMID:19598129. |
morphogenesis of the mammalian secondary palate requires coordination of cell migration, proliferation, differentiation, apoptosis and synthesis of extracellular matrix molecules by numerous signal transduction pathways. |
2009-10-19 |
2023-08-12 |
Not clear |
| Hee Joon Kang, Sang Hun Lee, Janet E Price, Lee Su Ki. Curcumin suppresses the paclitaxel-induced nuclear factor-kappaB in breast cancer cells and potentiates the growth inhibitory effect of paclitaxel in a breast cancer nude mice model. The breast journal. vol 15. issue 3. 2009-10-19. PMID:19645775. |
in an experimental breast cancer murine model using mda-mb-231 cells, combination therapy with paclitaxel and curcumin significantly reduced tumor size and decreased tumor cell proliferation, increased apoptosis, and decreased the expression of matrix metalloprotease 9 compared with either agent alone. |
2009-10-19 |
2023-08-12 |
mouse |
| Jesús San Migue. Characteristics, pathogenesis, and novel treatments for multiple myeloma. Journal of the National Comprehensive Cancer Network : JNCCN. vol 2 Suppl 4. 2009-10-14. PMID:19791422. |
adhesion to the extracellular matrix and bone marrow stromal cells augments drug resistance and inhibits apoptosis. |
2009-10-14 |
2023-08-12 |
Not clear |
| Hiroyuki Tsutsui, Shintaro Kinugawa, Shouji Matsushim. Oxidative stress and mitochondrial DNA damage in heart failure. Circulation journal : official journal of the Japanese Circulation Society. vol 72 Suppl A. 2009-10-02. PMID:18772530. |
reactive oxygen species induce myocyte hypertrophy, apoptosis, and interstitial fibrosis by activating matrix metalloproteinases. |
2009-10-02 |
2023-08-12 |
Not clear |
| Neena Philips, Luiji Dulaj, Tajali Upadhy. Cancer cell growth and extracellular matrix remodeling mechanism of ascorbate; beneficial modulation by P. leucotomos. Anticancer research. vol 29. issue 8. 2009-09-30. PMID:19661340. |
we examined melanoma cell viability and ecm remodeling mechanisms of ascorbate and its modulation by an extract from polypodium leucotomos (pl) (a fern) via the regulation of apoptosis, heat-shock proteins (hsps), mmp-1 or tissue inhibitors of matrix metalloproteinase-1 (timp-1) that inhibits mmp-1. |
2009-09-30 |
2023-08-12 |
Not clear |
| M W Roomi, N W Roomi, T Kalinovsky, M Rath, A Niedzwieck. Marked inhibition of growth and invasive parameters of head and neck squamous carcinoma FaDu by a nutrient mixture. Integrative cancer therapies. vol 8. issue 2. 2009-09-29. PMID:19679626. |
cell proliferation was assessed by mtt assay, matrix metalloproteinase (mmp) secretion by gelatinase zymography, invasion through matrigel, apoptosis by live-green caspases, and cell morphology by hematoxylin-eosin staining. |
2009-09-29 |
2023-08-12 |
mouse |
| Wei Shi, Qingqing Tang, Xiancheng Chen, Ping Cheng, Peidu Jiang, Xiaomei Jing, Xiang Chen, Ping Chen, Yongsheng Wang, Yuquan Wei, Yanjun We. Antitumor and antimetastatic activities of vesicular stomatitis virus matrix protein in a murine model of breast cancer. Journal of molecular medicine (Berlin, Germany). vol 87. issue 5. 2009-09-28. PMID:19259640. |
vesicular stomatitis virus (vsv) matrix protein (mp) is capable of inducing in vitro apoptosis of tumor cells in the absence of other viral components. |
2009-09-28 |
2023-08-12 |
mouse |