| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Zhang, L Zhao, D Zhao, G Lin, B Guo, Y Li, Z Liang, X J Zhao, X Fan. Inhibition of tumor growth and induction of apoptosis in prostate cancer cell lines by overexpression of tissue inhibitor of matrix metalloproteinase-3. Cancer gene therapy. vol 17. issue 3. 2010-05-04. PMID:19798124. |
inhibition of tumor growth and induction of apoptosis in prostate cancer cell lines by overexpression of tissue inhibitor of matrix metalloproteinase-3. |
2010-05-04 |
2023-08-12 |
mouse |
| James Wes. Cross talk between Smad, MAPK, and actin in the etiology of pulmonary arterial hypertension. Advances in experimental medicine and biology. vol 661. 2010-04-26. PMID:20204736. |
functional consequences of bmpr2 mutation, largely ascertained from animal models, include a shift from contractile to synthetic phenotype in smooth muscle, probably downstream of smad signal; alterations in expression of actin organization related genes, possibly related to focal adhesions; alterations in cytokines and inflammatory cell recruitment; increased proliferation and apoptosis; and increased collagen and matrix. |
2010-04-26 |
2023-08-12 |
Not clear |
| Hisataka Kitano, Shinichiro Kokubun, Chiaki Hida. The extracellular matrix protein Del1 induces apoptosis via its epidermal growth factor motif. Biochemical and biophysical research communications. vol 393. issue 4. 2010-04-20. PMID:20171188. |
the extracellular matrix protein del1 induces apoptosis via its epidermal growth factor motif. |
2010-04-20 |
2023-08-12 |
mouse |
| G Vinothini, C Balachandran, S Nagin. Evaluation of molecular markers in canine mammary tumors: correlation with histological grading. Oncology research. vol 18. issue 5-6. 2010-04-20. PMID:20225757. |
we analyzed changes in the expression of markers of hormone and receptor status (estradiol, estrogen receptor; er and her-2/neu), hormone metabolism (cyp1a1 and cyp1b1), cell proliferation and survival [proliferating cell nuclear antigen (pcna), glutathione s-transferase-p (gst-p), nuclear factor-kappab (nf-kappab-p50, nf-kappab-p65), phosphorylated-inhibitor of kappab-alpha (p-ikappab-alpha) and ikappab], apoptosis (bcl-2, bax, caspases, apaf-1, cytochrome-c, and parp), invasion [matrix metalloproteinases-2 and -9 (mmp-2, mmp-9), tissue inhibitor of matrix metalloproteinase-2 (timp-2), and reversion-inducing cysteine-rich protein with kazal motifs (reck)], angiogenesis [vascular endothelial growth factor (vegf)], and epigenetics [dna methyltransferase (dnmt-1), histone deacetylase (hdac-1)] by immunohistochemical localization and western blot analysis and correlated these with histological grade. |
2010-04-20 |
2023-08-12 |
human |
| Anguraj Sadanandam, Erin G Rosenbaugh, Seema Singh, Michelle Varney, Rakesh K Sing. Semaphorin 5A promotes angiogenesis by increasing endothelial cell proliferation, migration, and decreasing apoptosis. Microvascular research. vol 79. issue 1. 2010-04-12. PMID:19850054. |
in addition, our data suggest that sema5a decreases apoptosis through activation of akt, increases migration through activating met tyrosine kinases and extracellular matrix degradation through matrix metalloproteinase 9. |
2010-04-12 |
2023-08-12 |
mouse |
| Adam J W Paige, Manuela Zucknick, Szymon Janczar, Jim Paul, Charles A Mein, Karen J Taylor, Moira Stewart, Charlie Gourley, Sylvia Richardson, Timothy Perren, Trivadi S Ganesan, John F Smyth, Robert Brown, Hani Gabr. WWOX tumour suppressor gene polymorphisms and ovarian cancer pathology and prognosis. European journal of cancer (Oxford, England : 1990). vol 46. issue 4. 2010-04-09. PMID:20074932. |
in ovarian cancer cells wwox transfection abolishes tumourigenicity, suppresses tumour cell adhesion to extracellular matrix and induces apoptosis in non-adherent cells. |
2010-04-09 |
2023-08-12 |
mouse |
| Sophie Rösler, Tobias Haase, Horst Claassen, Ute Schulze, Martin Schicht, Dagmar Riemann, Jörg Brandt, David Wohlrab, Brigitte Müller-Hilke, Mary B Goldring, Saadettin Sel, Deike Varoga, Fabian Garreis, Friedrich P Paulse. Trefoil factor 3 is induced during degenerative and inflammatory joint disease, activates matrix metalloproteinases, and enhances apoptosis of articular cartilage chondrocytes. Arthritis and rheumatism. vol 62. issue 3. 2010-04-02. PMID:20131235. |
trefoil factor 3 is induced during degenerative and inflammatory joint disease, activates matrix metalloproteinases, and enhances apoptosis of articular cartilage chondrocytes. |
2010-04-02 |
2023-08-12 |
Not clear |
| Meagan M Grudzien, Philip Steven Low, Peter C Manning, Melissa Arredondo, Robert J Belton, Romana A Nowa. The antifibrotic drug halofuginone inhibits proliferation and collagen production by human leiomyoma and myometrial smooth muscle cells. Fertility and sterility. vol 93. issue 4. 2010-04-01. PMID:19135664. |
to investigate the effects of the antifibrotic drug halofuginone on extracellular matrix production, cell proliferation, and apoptosis of cultured myometrial and leiomyoma smooth muscle cells. |
2010-04-01 |
2023-08-12 |
human |
| Lusine Aghajanova, Jose A Horcajadas, James L Weeks, Francisco J Esteban, Camran N Nezhat, Marco Conti, Linda C Giudic. The protein kinase A pathway-regulated transcriptome of endometrial stromal fibroblasts reveals compromised differentiation and persistent proliferative potential in endometriosis. Endocrinology. vol 151. issue 3. 2010-03-26. PMID:20068008. |
hesf(endo) treated with 8-br-camp exhibited altered expression of immune response, extracellular matrix, cytoskeleton, and apoptosis genes. |
2010-03-26 |
2023-08-12 |
human |
| Johanna Myllyharju, Ernestina Schipan. Extracellular matrix genes as hypoxia-inducible targets. Cell and tissue research. vol 339. issue 1. 2010-03-23. PMID:19662436. |
the ability of cells to survive under hypoxia or to adapt to it depends on a family of hypoxia-inducible transcription factors (hifs) that induce the expression of a number of genes involved in hematopoiesis, angiogenesis, iron transport, glucose utilization, resistance to oxidative stress, cell proliferation, survival and apoptosis, and extracellular matrix homeostasis. |
2010-03-23 |
2023-08-12 |
human |
| Gary Sweene. Cardiovascular effects of leptin. Nature reviews. Cardiology. vol 7. issue 1. 2010-03-23. PMID:19949425. |
accordingly, many studies have examined the contribution of leptin to cardiac remodeling in heart failure and whether the effects of leptin on metabolism, apoptosis, extracellular matrix remodeling, and hypertrophy could explain the so-called obesity paradox. |
2010-03-23 |
2023-08-12 |
human |
| Jort Robertus, Wesley R Browne, Ben L Fering. Dynamic control over cell adhesive properties using molecular-based surface engineering strategies. Chemical Society reviews. vol 39. issue 1. 2010-03-23. PMID:20023857. |
in complex organisms, cells are often dependent on their extracellular matrix (ecm) for structural integrity, the mechanical properties of tissues, and for signaled regulation of cellular processes including adhesion, migration, growth, secretion, gene expression and apoptosis. |
2010-03-23 |
2023-08-12 |
Not clear |
| Hideto Sano, Jared P Leboeuf, Sergey V Novitskiy, Seungwoon Seo, Snjezana Zaja-Milatovic, Mikhail M Dikov, Tsutomu Kum. The Foxc2 transcription factor regulates tumor angiogenesis. Biochemical and biophysical research communications. vol 392. issue 2. 2010-03-19. PMID:20060810. |
consistently, expression levels of several angiogenic factors, including vascular endothelial growth factor (vegf), matrix metallopeptidase 2 (mmp2), and platelet-derived growth factor-b (pdgfb), were significantly decreased in b16 tumors grown in foxc2+/- mice, and tumor blood vessels formed in foxc2+/- mice showed reduced coverage of mural cells and endothelial cell apoptosis. |
2010-03-19 |
2023-08-12 |
mouse |
| Yury Popov, Deanna Y Sverdlov, K Ramakrishnan Bhaskar, Anisha K Sharma, Gunda Millonig, Eleonora Patsenker, Stephan Krahenbuhl, Lukas Krahenbuhl, Detlef Schuppa. Macrophage-mediated phagocytosis of apoptotic cholangiocytes contributes to reversal of experimental biliary fibrosis. American journal of physiology. Gastrointestinal and liver physiology. vol 298. issue 3. 2010-03-15. PMID:20056896. |
we investigated the possible functional link between apoptosis, macrophages, and matrix turnover in rat liver during reversal of fibrosis secondary to bile duct ligation (bdl). |
2010-03-15 |
2023-08-12 |
rat |
| Alexandra Krettek, Sara Sjöber. CD44 - a new cardiovascular drug target or merely an innocent bystander? Cardiovascular & hematological disorders drug targets. vol 9. issue 4. 2010-03-09. PMID:20044914. |
although major functions involve adhesion and migration, cd44 also affects leukocyte homing and recruitment, phagocytosis, matrix remodeling, proliferation, and apoptosis. |
2010-03-09 |
2023-08-12 |
human |
| Ju-mei Zhao, Tao Liu, Yu-quan Wei, Yan-jun Wen, Yang W. [Apoptosis of colon carcinoma cells of mice induced by vesicular stomatitis virus matrix protein in vitro]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition. vol 40. issue 2. 2010-03-04. PMID:19462891. |
[apoptosis of colon carcinoma cells of mice induced by vesicular stomatitis virus matrix protein in vitro]. |
2010-03-04 |
2023-08-12 |
mouse |
| Toshio Imai, Hisataka Ii, Ken Yaegaki, Takatoshi Murata, Tsutomu Sato, Takeshi Kamod. Oral malodorous compound inhibits osteoblast proliferation. Journal of periodontology. vol 80. issue 12. 2010-03-04. PMID:19961386. |
previous studies demonstrated that volatile sulfur compounds (vscs) were highly toxic to periodontal tissues, causing a large reduction in the amount of collagen in human gingival fibroblasts and extracellular matrix as well as, for example, apoptosis, immunologic responses, and matrix metalloproteinase production. |
2010-03-04 |
2023-08-12 |
human |
| Qin Guo, Minghua Wu, Ping Lian, Mantian Liao, Zhiming Xiao, Xiaoyan Wang, Shourong She. Synergistic effect of indomethacin and NGX6 on proliferation and invasion by human colorectal cancer cells through modulation of the Wnt/beta-catenin signaling pathway. Molecular and cellular biochemistry. vol 330. issue 1-2. 2010-03-02. PMID:19353243. |
however, they did not have synergistic effects on enhancing apoptosis and suppressing extracellular matrix adhesion of ht-29 and sw620 cells. |
2010-03-02 |
2023-08-12 |
human |
| Gerardo Caruso, Mariella Caffo, Giuseppe Raudino, Concetta Alafaci, Francesco M Salpietro, Francesco Tomasell. Antisense oligonucleotides as innovative therapeutic strategy in the treatment of high-grade gliomas. Recent patents on CNS drug discovery. vol 5. issue 1. 2010-03-01. PMID:19832690. |
the extracellular matrix plays a pivotal role in processes such as differentiation, apoptosis, and migration in both the normal and the pathologic nervous system. |
2010-03-01 |
2023-08-12 |
Not clear |
| Erzsébet Gáspár, Celine Hardenbicker, Eniko Bodó, Björn Wenzel, Yuval Ramot, Wolfgang Funk, Arno Kromminga, Ralf Pau. Thyrotropin releasing hormone (TRH): a new player in human hair-growth control. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 24. issue 2. 2010-02-25. PMID:19825978. |
it also increases proliferation and inhibits apoptosis of hair matrix keratinocytes. |
2010-02-25 |
2023-08-12 |
human |