| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tao Wu, Luna Yang, Yan Chen, Yinhua Ni, Jianguo Jiang, Wanjing Zhang, Qianchen Zhou, Xiaojun Zheng, Qi Wang, Zhengwei Fu, Haifeng L. Pilose antler polypeptides ameliorates hypoxic-ischemic encephalopathy by activated neurotrophic factors and SDF1/CXCR4 axis in rats. Acta biochimica et biophysica Sinica. vol 50. issue 3. 2018-10-02. PMID:29385398. |
real-time quantitative polymerase chain reaction (rt-qpcr) analysis indicated that pap administration decreased the expressions of inflammatory cytokines and apoptosis genes in hippocampus compared with hi group. |
2018-10-02 |
2023-08-13 |
rat |
| Gui-Nan Shen, Lei Liu, Li Feng, Yu Jin, Mei-Hua Jin, Ying-Hao Han, Cheng-Hao Jin, Yong-Zhe Jin, Dong-Soek Lee, Tae Ho Kwon, Yu-Dong Cui, Hu-Nan Su. Knockdown of peroxiredoxin V increases glutamate‑induced apoptosis in HT22 hippocampal neuron cells. Molecular medicine reports. vol 17. issue 6. 2018-09-26. PMID:29620243. |
knockdown of peroxiredoxin v increases glutamate‑induced apoptosis in ht22 hippocampal neuron cells. |
2018-09-26 |
2023-08-13 |
Not clear |
| Man-He Zhang, Xiu-Min Zhou, Jian-Zhong Cui, Kai-Jie Wang, Yan Feng, Hong-Ao Zhan. Neuroprotective effects of dexmedetomidine on traumatic brain injury: Involvement of neuronal apoptosis and HSP70 expression. Molecular medicine reports. vol 17. issue 6. 2018-09-26. PMID:29693126. |
the aim of the present study was to investigate the protective effect of dexmedetomidine (dex) on traumatic brain injury (tbi), and further evaluate whether the underlying neuroprotective mechanisms are associated with neurological apoptosis and the expression of 70 kda heat shock protein (hsp70) in the hippocampus. |
2018-09-26 |
2023-08-13 |
rat |
| Man-He Zhang, Xiu-Min Zhou, Jian-Zhong Cui, Kai-Jie Wang, Yan Feng, Hong-Ao Zhan. Neuroprotective effects of dexmedetomidine on traumatic brain injury: Involvement of neuronal apoptosis and HSP70 expression. Molecular medicine reports. vol 17. issue 6. 2018-09-26. PMID:29693126. |
in conclusion, the results of the present study suggested that administration of dex may serve as a neuroprotective agent against brain injury, at least partially via the inhibition of neuronal apoptosis and upregulation of hsp70 expression in the hippocampus. |
2018-09-26 |
2023-08-13 |
rat |
| Xiaofeng Lei, Lijian Lei, Zhiqing Zhang, Yan Chen. Diazoxide inhibits of ER stress‑mediated apoptosis during oxygen‑glucose deprivation in vitro and cerebral ischemia‑reperfusion in vivo. Molecular medicine reports. vol 17. issue 6. 2018-09-26. PMID:29693708. |
however, the effects of dzx on er stress during i/r‑induced neuronal apoptosis in the hippocampus remains to be elucidated. |
2018-09-26 |
2023-08-13 |
rat |
| Xiaofeng Lei, Lijian Lei, Zhiqing Zhang, Yan Chen. Diazoxide inhibits of ER stress‑mediated apoptosis during oxygen‑glucose deprivation in vitro and cerebral ischemia‑reperfusion in vivo. Molecular medicine reports. vol 17. issue 6. 2018-09-26. PMID:29693708. |
in the present study, pretreatment of hippocampal neurons with dzx was revealed to inhibit oxygen‑glucose deprivation (ogd)‑stimulated apoptosis in vitro and to alleviate i/r‑induced hippocampal injury and behavioral deficits in rats in vivo. |
2018-09-26 |
2023-08-13 |
rat |
| Xiaofeng Lei, Lijian Lei, Zhiqing Zhang, Yan Chen. Diazoxide inhibits of ER stress‑mediated apoptosis during oxygen‑glucose deprivation in vitro and cerebral ischemia‑reperfusion in vivo. Molecular medicine reports. vol 17. issue 6. 2018-09-26. PMID:29693708. |
these findings suggested that dzx may protect cells against apoptosis via regulating the expression of er stress‑associated proteins in vitro and in vivo, thus enhancing the survival of hippocampal cells. |
2018-09-26 |
2023-08-13 |
rat |
| Chao Chen, Bin Li, Guangqing Cheng, Xiaoni Yang, Ningning Zhao, Ran Sh. Amentoflavone Ameliorates Aβ Neurochemical research. vol 43. issue 4. 2018-09-24. PMID:29411261. |
cell survival and apoptosis in the hippocampal region in an animal model were detected using nissl staining and a terminal deoxynucleotidyl transferased utp nick-end labeling assay, respectively. |
2018-09-24 |
2023-08-13 |
rat |
| Chao Chen, Bin Li, Guangqing Cheng, Xiaoni Yang, Ningning Zhao, Ran Sh. Amentoflavone Ameliorates Aβ Neurochemical research. vol 43. issue 4. 2018-09-24. PMID:29411261. |
our results showed that af significantly attenuated aβ-induced deficits in neurological functions as well as neuronal cell death and apoptosis in the hippocampal region. |
2018-09-24 |
2023-08-13 |
rat |
| Yushan Cui, Zushan Zhang, Bin Zhang, Liang Zhao, Changchun Hou, Qiang Zeng, Junyan Nie, Jingwen Yu, Yang Zhao, Tongning Gao, Aiguo Wang, Hongliang Li. Excessive apoptosis and disordered autophagy flux contribute to the neurotoxicity induced by high iodine in Sprague-Dawley rat. Toxicology letters. vol 297. 2018-09-24. PMID:30172000. |
moreover, high iodine increased hippocampal apoptosis, as confirmed by elevation of apoptotic proteins and tunel-positive incidence. |
2018-09-24 |
2023-08-13 |
rat |
| Qingyun Li, Jinhua Wang, Yuwang Li, Xiaolin X. Neuroprotective effects of salidroside administration in a mouse model of Alzheimer's disease. Molecular medicine reports. vol 17. issue 5. 2018-09-21. PMID:29568861. |
in addition, terminal deoxynucleotidyl‑transferase‑mediated dutp nick end labeling was used to investigate the rate of neuronal apoptosis in the hippocampus. |
2018-09-21 |
2023-08-13 |
mouse |
| Guoyao Zang, Lizheng Fang, Liying Chen, Chenyao Wan. Ameliorative effect of nicergoline on cognitive function through the PI3K/AKT signaling pathway in mouse models of Alzheimer's disease. Molecular medicine reports. vol 17. issue 5. 2018-09-21. PMID:29568940. |
evidence suggests that nicergoline serves an important role in the apoptosis of hippocampal cells, memory recovery, cognitive function and neuronal survival. |
2018-09-21 |
2023-08-13 |
mouse |
| Guoyao Zang, Lizheng Fang, Liying Chen, Chenyao Wan. Ameliorative effect of nicergoline on cognitive function through the PI3K/AKT signaling pathway in mouse models of Alzheimer's disease. Molecular medicine reports. vol 17. issue 5. 2018-09-21. PMID:29568940. |
the apoptosis rates of hippocampal cells were studied in mice with alzheimer's disease treated with nicergoline compared with the negative control. |
2018-09-21 |
2023-08-13 |
mouse |
| Guoyao Zang, Lizheng Fang, Liying Chen, Chenyao Wan. Ameliorative effect of nicergoline on cognitive function through the PI3K/AKT signaling pathway in mouse models of Alzheimer's disease. Molecular medicine reports. vol 17. issue 5. 2018-09-21. PMID:29568940. |
the results of the present study demonstrated that nicergoline ameliorated apoptosis in hippocampal cells and hippocampus tissue in 3xtg‑ad mice with alzheimer's disease. |
2018-09-21 |
2023-08-13 |
mouse |
| Zhao Li, Shuang Zhao, Hai-Lin Zhang, Peng Liu, Fei-Fei Liu, Yue-Xian Guo, Xiu-Li Wan. Proinflammatory Factors Mediate Paclitaxel-Induced Impairment of Learning and Memory. Mediators of inflammation. vol 2018. 2018-09-17. PMID:29681766. |
neuronal apoptosis was assessed by tunel assay in the hippocampus. |
2018-09-17 |
2023-08-13 |
Not clear |
| Yu Zhou, Chaolin Ma, Bao-Ming Li, Chong Su. Polygala japonica Houtt. reverses depression-like behavior and restores reduced hippocampal neurogenesis in chronic stress mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 99. 2018-09-17. PMID:29710497. |
we also found that pj had no significant effect on cell proliferation and neuronal differentiation in dentate gyrus (dg) of the hippocampus, but it inhibited the apoptosis of the newborn neurons by activation of bcl-2 and phopho-erk1/2 and increased the number of the newborn neurons. |
2018-09-17 |
2023-08-13 |
mouse |
| Yu Zhou, Chaolin Ma, Bao-Ming Li, Chong Su. Polygala japonica Houtt. reverses depression-like behavior and restores reduced hippocampal neurogenesis in chronic stress mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 99. 2018-09-17. PMID:29710497. |
our results demonstrate that administration of pj to chronic stress mice alleviates depression-like behaviors and normalizes the deficit in hippocampal neurogenesis with inhibiting newborn neuron apoptosis. |
2018-09-17 |
2023-08-13 |
mouse |
| Shuai Lian, Di Wang, Bin Xu, Wenjin Guo, Lipeng Wang, Wenjie Li, Hong Ji, Jianfa Wang, Fanzhi Kong, Li Zhen, Shize Li, Liping Zhang, Jingru Guo, Huanmin Yan. Prenatal cold stress: Effect on maternal hippocampus and offspring behavior in rats. Behavioural brain research. vol 346. 2018-09-11. PMID:29421306. |
furthermore, we demonstrated that cold stress enhanced phosphorylation of p65 on ser536, and led to apoptosis of the hippocampus in a caspase 3-independent manner. |
2018-09-11 |
2023-08-13 |
rat |
| Weronika Krzyżanowska, Bartosz Pomierny, Beata Starek-Świechowicz, Żaneta Broniowska, Beata Strach, Bogusława Budziszewsk. The effects of benzophenone-3 on apoptosis and the expression of sex hormone receptors in the frontal cortex and hippocampus of rats. Toxicology letters. vol 296. 2018-09-04. PMID:30099065. |
the effects of benzophenone-3 on apoptosis and the expression of sex hormone receptors in the frontal cortex and hippocampus of rats. |
2018-09-04 |
2023-08-13 |
rat |
| Weronika Krzyżanowska, Bartosz Pomierny, Beata Starek-Świechowicz, Żaneta Broniowska, Beata Strach, Bogusława Budziszewsk. The effects of benzophenone-3 on apoptosis and the expression of sex hormone receptors in the frontal cortex and hippocampus of rats. Toxicology letters. vol 296. 2018-09-04. PMID:30099065. |
the aim of the present study was to determine the effects of bp-3 on apoptosis and the expression of oestrogen, androgen and arylhydrocarbon receptors (ahr) in the rat frontal cortex and hippocampus. |
2018-09-04 |
2023-08-13 |
rat |