| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wei Jiang, Min Guo, Min Gong, Li Chen, Yang Bi, Yun Zhang, Yuan Shi, Ping Qu, Youxue Liu, Jie Chen, Tingyu L. Vitamin A bio-modulates apoptosis via the mitochondrial pathway after hypoxic-ischemic brain damage. Molecular brain. vol 11. issue 1. 2018-10-22. PMID:29534734. |
additionally, we showed that hippocampal apoptosis was weaker in the van group than that in vad group. |
2018-10-22 |
2023-08-13 |
rat |
| Hanwoong Woo, Caroline Jeeyeon Hong, Seonghee Jung, Seongwon Choe, Seong-Woon Y. Chronic restraint stress induces hippocampal memory deficits by impairing insulin signaling. Molecular brain. vol 11. issue 1. 2018-10-22. PMID:29970188. |
corticosterone treatment of mouse hippocampal neurons in vitro caused neurotoxicity with an increase in the markers of autophagy but not apoptosis. |
2018-10-22 |
2023-08-13 |
mouse |
| Jian Han, Qi-Hua Yin, Yang Fang, Wei-Qing Shou, Cong-Cong Zhang, Fu-Qiang Gu. Atorvastatin protects BV‑2 mouse microglia and hippocampal neurons against oxygen‑glucose deprivation‑induced neuronal inflammatory injury by suppressing the TLR4/TRAF6/NF‑κB pathway. Molecular medicine reports. vol 18. issue 1. 2018-10-19. PMID:29845194. |
atorvastatin also inhibited the apoptosis of ogd hippocampal neurons by regulating the expression of apoptosis‑associated proteins. |
2018-10-19 |
2023-08-13 |
mouse |
| D Sağır, B Eren, B D Yılmaz, Z Eren, O N Keleş, A B Gökç. Effects of prenatal PPAR-γ agonist rosiglitazone exposure on rat hippocampus development in a time-dependent manner: A stereological and histopathological study. Human & experimental toxicology. vol 37. issue 8. 2018-10-18. PMID:29025280. |
hdr affected apoptosis or the proliferation and maturation of progenitor cells to the pyramidal neuron during neurodevelopment in the hippocampus, whereas ldr did not adversely affect neuronal development and did not cause congenital anomalies. |
2018-10-18 |
2023-08-13 |
rat |
| Wei Jiang, Xian Zhang, Ai-Ling Zho. [The role of TLR Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 32. issue 6. 2018-10-18. PMID:29926630. |
[the role of tlr to investigate the effects of the toll like receptor 4 (tlr4) -p38-jnk signaling pathway in the apoptosis of hippocampal neurons in rats and its mechanisms. |
2018-10-18 |
2023-08-13 |
rat |
| Lei Wu, Yushuang Li, Minhua Yu, Fei Yang, Mengqi Tu, Haibo X. Notch Signaling Regulates Microglial Activation and Inflammatory Reactions in a Rat Model of Temporal Lobe Epilepsy. Neurochemical research. vol 43. issue 6. 2018-10-15. PMID:29737480. |
likewise, the neuronal apoptosis and loss in the hippocampus after se were attenuated by the γ-secretase inhibitor. |
2018-10-15 |
2023-08-13 |
rat |
| Zhaoling Shi, Chen Li, Yue Yin, Zheng Yang, Han Xue, Nan Mu, Yishi Wang, Manling Liu, Heng M. Aerobic Interval Training Regulated SIRT3 Attenuates High-Fat-Diet-Associated Cognitive Dysfunction. BioMed research international. vol 2018. 2018-10-15. PMID:29765980. |
as a result, the ros and mda levels were significantly increased, which leads to the neuron apoptosis in the hippocampus. |
2018-10-15 |
2023-08-13 |
mouse |
| Zhaoling Shi, Chen Li, Yue Yin, Zheng Yang, Han Xue, Nan Mu, Yishi Wang, Manling Liu, Heng M. Aerobic Interval Training Regulated SIRT3 Attenuates High-Fat-Diet-Associated Cognitive Dysfunction. BioMed research international. vol 2018. 2018-10-15. PMID:29765980. |
the hippocampus neuron oxidative stress and apoptosis were both decreased compared to untrained hfd group, which finally improved cognitive function of hfd mice. |
2018-10-15 |
2023-08-13 |
mouse |
| Giti Kalantarian, Nasrin Ziamajidi, Reza Mahjub, Mohammad Taghi Goodarzi, Massoud Saidijam, Sara Soleimani Asl, Roghayeh Abbasalipourkabi. Effect of insulin-coated trimethyl chitosan nanoparticles on IGF-1, IGF-2, and apoptosis in the hippocampus of diabetic male rats. Restorative neurology and neuroscience. vol 36. issue 4. 2018-10-15. PMID:29889083. |
effect of insulin-coated trimethyl chitosan nanoparticles on igf-1, igf-2, and apoptosis in the hippocampus of diabetic male rats. |
2018-10-15 |
2023-08-13 |
rat |
| Shuang Liu, Xiaohui Li, Jianmei Gao, Yuangui Liu, Jingshan Shi, Qihai Gon. Icariside II, a Phosphodiesterase-5 Inhibitor, Attenuates Beta-Amyloid-Induced Cognitive Deficits via BDNF/TrkB/CREB Signaling. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 49. issue 3. 2018-10-12. PMID:30196289. |
our previous study has proved that ics ii protects against learning and memory impairments and neuronal apoptosis in the hippocampus induced by beta-amyloid25-35 (aβ25-35) in rats. |
2018-10-12 |
2023-08-13 |
rat |
| Jian Chen, Yanli Bi, Lei Chen, Qi Zhang, Linhao X. Tanshinone IIA exerts neuroprotective effects on hippocampus-dependent cognitive impairments in diabetic rats by attenuating ER stress-induced apoptosis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 104. 2018-10-11. PMID:29800917. |
this study aimed to investigate the mechanism by which tanshinone iia (tan iia) suppresses neuronal apoptosis in the hippocampus of diabetic rats. |
2018-10-11 |
2023-08-13 |
rat |
| Jian Chen, Yanli Bi, Lei Chen, Qi Zhang, Linhao X. Tanshinone IIA exerts neuroprotective effects on hippocampus-dependent cognitive impairments in diabetic rats by attenuating ER stress-induced apoptosis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 104. 2018-10-11. PMID:29800917. |
superoxide dismutase (sod) activity was reduced, and reactive oxygen species (ros) production, malondialdehyde (mda) content, and 78-kda glucose-regulated protein (grp78), growth arrest and dna damage-inducible gene 153 (chop/gad153) and cleaved caspase-3 levels were increased in the hippocampus of diabetic rats compared with that of control rats, changes that were accompanied by an increase in neuronal apoptosis in diabetic rats compared with control rats (p < 0.01). |
2018-10-11 |
2023-08-13 |
rat |
| Qinghua Zhang, Yang Liu, Hui Wang, Li Ma, Hechun Xia, Jianguo Niu, Tao Sun, Li Zhan. The preventive effects of taurine on neural tube defects through the Wnt/PCP-Jnk-dependent pathway. Amino acids. vol 49. issue 9. 2018-10-10. PMID:28718066. |
ht-22 cells (a hippocampal neuron cell line) were divided into a control group, a glutamate-induced apoptosis group, and glutamate (4.0 mmol/l) plus low-dose taurine (l; 0.5 mmol/l) and high-dose taurine (h; 2.0 mmol/l) groups. |
2018-10-10 |
2023-08-13 |
mouse |
| Zai-Ming Liu, Qian-Xue Chen, Zhi-Biao Chen, Dao-Feng Tian, Ming-Chang Li, Jun-Min Wang, Long Wang, Bao-Hui Liu, Shen-Qi Zhang, Fei Li, Hui Ye, Long Zho. RIP3 deficiency protects against traumatic brain injury (TBI) through suppressing oxidative stress, inflammation and apoptosis: Dependent on AMPK pathway. Biochemical and biophysical research communications. vol 499. issue 2. 2018-10-09. PMID:29470982. |
further, tbi induced hippocampus apoptosis, evidenced by the increase of cleaved caspase-8/-3 and poly (adp)-ribose polymerase (parp) in wt mice, whereas being decreased by rip3-knockout. |
2018-10-09 |
2023-08-13 |
mouse |
| Qipeng Zhao, Ailing Chen, Xiaobo Wang, Zhuanzhuan Zhang, Yunsheng Zhao, Yu Huang, Shuanglai Ren, Yafei Zh. Protective effects of dehydrocostuslactone on rat hippocampal slice injury induced by oxygen‑glucose deprivation/reoxygenation. International journal of molecular medicine. vol 42. issue 2. 2018-10-09. PMID:29786748. |
these results suggested that dhl elicited protective effects against hippocampal ogd/r injury, and its underlying mechanism may be associated with inhibiting apoptosis. |
2018-10-09 |
2023-08-13 |
rat |
| Piangkwan Sa-Nguanmoo, Pongpan Tanajak, Sasiwan Kerdphoo, Thidarat Jaiwongkam, Xiaojie Wang, Guang Liang, Xiaokun Li, Chao Jiang, Wasana Pratchayasakul, Nipon Chattipakorn, Siriporn C Chattipakor. FGF21 and DPP-4 inhibitor equally prevents cognitive decline in obese rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 97. 2018-10-05. PMID:29793329. |
the results demonstrated that the rats fed on hfd had obese-insulin resistance, increased systemic inflammation, brain mitochondrial dysfunction, increased brain apoptosis, impaired hippocampal plasticity, and demonstrated cognitive decline. |
2018-10-05 |
2023-08-13 |
human |
| Shuangyue Li, Lijun Yang, Yan Zhang, Cong Zhang, Jing Shao, Xiaohui Liu, Yachen Li, Fengyuan Pia. Taurine Ameliorates Arsenic-Induced Apoptosis in the Hippocampus of Mice Through Intrinsic Pathway. Advances in experimental medicine and biology. vol 975 Pt 1. 2018-10-02. PMID:28849454. |
taurine ameliorates arsenic-induced apoptosis in the hippocampus of mice through intrinsic pathway. |
2018-10-02 |
2023-08-13 |
mouse |
| Shuangyue Li, Lijun Yang, Yan Zhang, Cong Zhang, Jing Shao, Xiaohui Liu, Yachen Li, Fengyuan Pia. Taurine Ameliorates Arsenic-Induced Apoptosis in the Hippocampus of Mice Through Intrinsic Pathway. Advances in experimental medicine and biology. vol 975 Pt 1. 2018-10-02. PMID:28849454. |
our group previously reported that arsenic (as) exposure induced apoptosis in hippocampus neurons. |
2018-10-02 |
2023-08-13 |
mouse |
| Shuangyue Li, Lijun Yang, Yan Zhang, Cong Zhang, Jing Shao, Xiaohui Liu, Yachen Li, Fengyuan Pia. Taurine Ameliorates Arsenic-Induced Apoptosis in the Hippocampus of Mice Through Intrinsic Pathway. Advances in experimental medicine and biology. vol 975 Pt 1. 2018-10-02. PMID:28849454. |
the aim of the present study was to clarify the protective capacity of taurine (tau) on as-induced neuronal apoptosis and the related mechanism in mouse hippocampus. |
2018-10-02 |
2023-08-13 |
mouse |
| Shuangyue Li, Lijun Yang, Yan Zhang, Cong Zhang, Jing Shao, Xiaohui Liu, Yachen Li, Fengyuan Pia. Taurine Ameliorates Arsenic-Induced Apoptosis in the Hippocampus of Mice Through Intrinsic Pathway. Advances in experimental medicine and biology. vol 975 Pt 1. 2018-10-02. PMID:28849454. |
the results indicated that tau supplement markedly ameliorates as-induced apoptosis by mitochondria-related pathway in mouse hippocampus. |
2018-10-02 |
2023-08-13 |
mouse |