| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F Chrétien, A Dorandeu, H Adle-Biassette, T Ereau, L Wingertsmann, F Brion, F Gra. [A process of programmed cell death as a mechanisms of neuronal death in prion diseases]. Clinical and experimental pathology. vol 47. issue 3-4. 1999-09-30. PMID:10472738. |
apoptosis of rat hippocampal neurons, in cultures exposed to a synthetic peptide homologous to the prion protein, has been identified on morphological criteria after staining by a fluorescent marker of dna and by gel electrophoresis of neuronal dna. |
1999-09-30 |
2023-08-12 |
mouse |
| A J Krohn, T Wahlbrink, J H Preh. Mitochondrial depolarization is not required for neuronal apoptosis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 17. 1999-09-23. PMID:10460246. |
we induced apoptosis in cultured rat hippocampal neurons by exposure to the protein kinase inhibitor staurosporine (sts) (300 nm). |
1999-09-23 |
2023-08-12 |
rat |
| C D Albright, C B Friedrich, E C Brown, M H Mar, S H Zeise. Maternal dietary choline availability alters mitosis, apoptosis and the localization of TOAD-64 protein in the developing fetal rat septum. Brain research. Developmental brain research. vol 115. issue 2. 1999-09-13. PMID:10407130. |
these results show that dietary choline availability during pregnancy alters the timing of mitosis, apoptosis and the early commitment to neuronal differentiation by progenitor cells in regions of the fetal brain septum, as well as hippocampus, two brain regions known to be associated with learning and memory. |
1999-09-13 |
2023-08-12 |
rat |
| S L Chan, W S Griffin, M P Mattso. Evidence for caspase-mediated cleavage of AMPA receptor subunits in neuronal apoptosis and Alzheimer's disease. Journal of neuroscience research. vol 57. issue 3. 1999-09-08. PMID:10412022. |
we now report that caspase activity is increased in brain tissue and neurons from ad patients, and in cultured hippocampal neurons undergoing apoptosis after exposure to amyloid beta-peptide (abeta). |
1999-09-08 |
2023-08-12 |
Not clear |
| S L Chan, S P Tammariello, S Estus, M P Mattso. Prostate apoptosis response-4 mediates trophic factor withdrawal-induced apoptosis of hippocampal neurons: actions prior to mitochondrial dysfunction and caspase activation. Journal of neurochemistry. vol 73. issue 2. 1999-08-13. PMID:10428045. |
prostate apoptosis response-4 mediates trophic factor withdrawal-induced apoptosis of hippocampal neurons: actions prior to mitochondrial dysfunction and caspase activation. |
1999-08-13 |
2023-08-12 |
rat |
| I Gomes, W Xiong, T Miki, M R Rosne. A proline- and glutamine-rich protein promotes apoptosis in neuronal cells. Journal of neurochemistry. vol 73. issue 2. 1999-08-13. PMID:10428057. |
to determine whether pqr acts as a mediator of apoptosis in neuronal cells, the hippocampal h19-7 cells were microinjected with either a plasmid expressing pqr cdna or an antibody against pqr. |
1999-08-13 |
2023-08-12 |
rat |
| I Gomes, W Xiong, T Miki, M R Rosne. A proline- and glutamine-rich protein promotes apoptosis in neuronal cells. Journal of neurochemistry. vol 73. issue 2. 1999-08-13. PMID:10428057. |
these results demonstrate that pqr can be induced by growth factors and differentiating agents and can itself induce apoptosis in hippocampal h19-7 cells. |
1999-08-13 |
2023-08-12 |
rat |
| I I Kruman, A Nath, W F Maragos, S L Chan, M Jones, V M Rangnekar, R J Jakel, M P Mattso. Evidence that Par-4 participates in the pathogenesis of HIV encephalitis. The American journal of pathology. vol 155. issue 1. 1999-07-26. PMID:10393834. |
we now report that levels of par-4, a protein recently linked to neuronal apoptosis in alzheimer's disease, are increased in neurons in hippocampus of human patients with hiv encephalitis and in monkeys infected with a chimeric strain of hiv-1 and simian immunodeficiency virus. |
1999-07-26 |
2023-08-12 |
human |
| I I Kruman, A Nath, W F Maragos, S L Chan, M Jones, V M Rangnekar, R J Jakel, M P Mattso. Evidence that Par-4 participates in the pathogenesis of HIV encephalitis. The American journal of pathology. vol 155. issue 1. 1999-07-26. PMID:10393834. |
par-4 levels increased rapidly in cultured hippocampal neurons following exposure to the neurotoxic hiv-1 protein tat, and treatment of the cultures with a par-4 antisense oligonucleotide protected the neurons against tat-induced apoptosis. |
1999-07-26 |
2023-08-12 |
human |
| b' G Bagetta, M T Corasaniti, L Berliocchi, R Nistic\\xc3\\xb3, A M Giammarioli, W Malorni, L Aloe, A Finazzi-Agr\\xc3\\xb. Involvement of interleukin-1beta in the mechanism of human immunodeficiency virus type 1 (HIV-1) recombinant protein gp120-induced apoptosis in the neocortex of rat. Neuroscience. vol 89. issue 4. 1999-07-22. PMID:10362294.' |
by contrast, in the hippocampus, gp120-enhanced interleukin-1beta expression elevates nerve growth factor that may prevent or delay apoptosis in this plastic region of the rat brain. |
1999-07-22 |
2023-08-12 |
human |
| B Ahlemeyer, A Glaser, C Schaper, I Semkova, J Krieglstei. The 5-HT1A receptor agonist Bay x 3702 inhibits apoptosis induced by serum deprivation in cultured neurons. European journal of pharmacology. vol 370. issue 2. 1999-07-16. PMID:10323272. |
in primary cultures of chick embryonic neurons and in mixed neuronal/glial cultures from neonatal rat hippocampus, bay x 3702 (1 microm) rescued serum-deprived neurons from apoptosis. |
1999-07-16 |
2023-08-12 |
rat |
| Y Zhu, J H Prehn, C Culmsee, J Krieglstei. The beta2-adrenoceptor agonist clenbuterol modulates Bcl-2, Bcl-xl and Bax protein expression following transient forebrain ischemia. Neuroscience. vol 90. issue 4. 1999-07-16. PMID:10338295. |
we have demonstrated previously that neuronal apoptosis can be induced in the hippocampus and striatum after global ischemia. |
1999-07-16 |
2023-08-12 |
rat |
| C C Weihl, G D Ghadge, S G Kennedy, N Hay, R J Miller, R P Roo. Mutant presenilin-1 induces apoptosis and downregulates Akt/PKB. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 13. 1999-07-15. PMID:10377346. |
using primary cultured hippocampal neurons (hns) and rat pheochromocytoma (pc12) cells transiently transfected with replication-defective recombinant adenoviral vectors expressing wild-type or mutant ps1, we demonstrate that mutant ps1s induce apoptosis, downregulate the survival factor akt/pkb, and affect several akt/pkb downstream targets, including glycogen synthase kinase-3beta and beta-catenin. |
1999-07-15 |
2023-08-12 |
rat |
| L K Weave. Carbon monoxide poisoning. Critical care clinics. vol 15. issue 2. 1999-07-01. PMID:10331130. |
additionally, various animal studies have demonstrated that co interferes with myoglobin, p450, and other enzyme function; causes lipid peroxidation through neutrophil activation; produces oxidative stress manifested by peroxynitrate deposition in endothelium; binds to cytochrome aa3, disrupting intracellular oxygen utilization; can cause neuroexcitotoxicity; and contributes to hippocampal cellular death through apoptosis. |
1999-07-01 |
2023-08-12 |
Not clear |
| D Xu, Y Bureau, D C McIntyre, D W Nicholson, P Liston, Y Zhu, W G Fong, S J Crocker, R G Korneluk, G S Robertso. Attenuation of ischemia-induced cellular and behavioral deficits by X chromosome-linked inhibitor of apoptosis protein overexpression in the rat hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 12. 1999-06-28. PMID:10366635. |
attenuation of ischemia-induced cellular and behavioral deficits by x chromosome-linked inhibitor of apoptosis protein overexpression in the rat hippocampus. |
1999-06-28 |
2023-08-12 |
rat |
| B Ahlemeyer, A Möwes, J Krieglstei. Inhibition of serum deprivation- and staurosporine-induced neuronal apoptosis by Ginkgo biloba extract and some of its constituents. European journal of pharmacology. vol 367. issue 2-3. 1999-06-22. PMID:10079019. |
we induced apoptosis in cultured chick embryonic neurons as well as in mixed cultures of neurons and astrocytes from neonatal rat hippocampus by serum deprivation and staurosporine. |
1999-06-22 |
2023-08-12 |
rat |
| S Krajewski, M Krajewska, L M Ellerby, K Welsh, Z Xie, Q L Deveraux, G S Salvesen, D E Bredesen, R E Rosenthal, G Fiskum, J C Ree. Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia. Proceedings of the National Academy of Sciences of the United States of America. vol 96. issue 10. 1999-06-17. PMID:10318956. |
similarly, in an animal model of transient global cerebral ischemia, caspase-9 release from mitochondria and accumulation in nuclei was observed in hippocampal and other vulnerable neurons exhibiting early postischemic changes preceding apoptosis. |
1999-06-17 |
2023-08-12 |
Not clear |
| Y Matsuoka, Y Kitamura, H Takahashi, I Tooyama, H Kimura, P J Gebicke-Haerter, Y Nomura, T Taniguch. Interferon-gamma plus lipopolysaccharide induction of delayed neuronal apoptosis in rat hippocampus. Neurochemistry international. vol 34. issue 2. 1999-06-10. PMID:10213066. |
interferon-gamma plus lipopolysaccharide induction of delayed neuronal apoptosis in rat hippocampus. |
1999-06-10 |
2023-08-12 |
rat |
| Y Matsuoka, Y Kitamura, H Takahashi, I Tooyama, H Kimura, P J Gebicke-Haerter, Y Nomura, T Taniguch. Interferon-gamma plus lipopolysaccharide induction of delayed neuronal apoptosis in rat hippocampus. Neurochemistry international. vol 34. issue 2. 1999-06-10. PMID:10213066. |
these results suggest that ifn-gamma/lps induces delayed neuronal apoptosis in the hippocampus in vivo, and it possibly involves excessive no production by inos. |
1999-06-10 |
2023-08-12 |
rat |
| M Tagami, K Ikeda, K Yamagata, Y Nara, H Fujino, A Kubota, F Numano, Y Yamor. Vitamin E prevents apoptosis in hippocampal neurons caused by cerebral ischemia and reperfusion in stroke-prone spontaneously hypertensive rats. Laboratory investigation; a journal of technical methods and pathology. vol 79. issue 5. 1999-05-28. PMID:10334572. |
vitamin e prevents apoptosis in hippocampal neurons caused by cerebral ischemia and reperfusion in stroke-prone spontaneously hypertensive rats. |
1999-05-28 |
2023-08-12 |
rat |