| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Tagami, K Ikeda, K Yamagata, Y Nara, H Fujino, A Kubota, F Numano, Y Yamor. Vitamin E prevents apoptosis in hippocampal neurons caused by cerebral ischemia and reperfusion in stroke-prone spontaneously hypertensive rats. Laboratory investigation; a journal of technical methods and pathology. vol 79. issue 5. 1999-05-28. PMID:10334572. |
cerebral ischemia followed by oxygen reperfusion induced apoptosis in hippocampal neurons in stroke-prone spontaneously hypertensive rats (shrsp) but not in wistar kyoto rats. |
1999-05-28 |
2023-08-12 |
rat |
| M Niwa, A Hara, T Iwai, M Nakashima, N Yoshimi, H Mori, T Uemats. Prevention of ischemia-induced hippocampal neuronal damage by 2-deoxy-D-glucose in gerbils. Life sciences. vol 64. issue 18. 1999-05-26. PMID:10328529. |
it has been reported that delayed neuronal death (dnd) in the hippocampus following transient forebrain ischemia is associated with internucleosomal dna fragmentation, indicating apoptosis. |
1999-05-26 |
2023-08-12 |
Not clear |
| T A Kent, M Quast, G Taglialatela, C Rea, J Wei, Z Tao, J R Perez-Pol. Effect of NGF treatment on outcome measures in a rat model of middle cerebral artery occlusion. Journal of neuroscience research. vol 55. issue 3. 1999-05-25. PMID:10348667. |
also, we observed that the striatum is an early target for oxidative stress that is followed by energy metabolic impairment and altered neurotrophin levels that were detected by noninvasive magnetic resonance imaging (mri) measurements of cytotoxicity and conventional biochemical determinations of apoptosis, glutathione, and nerve growth factor (ngf) protein levels in a pattern distinct from that observed in the hippocampus. |
1999-05-25 |
2023-08-12 |
rat |
| b' F J Gunn-Moore, J M Tavar\\xc3\\xa. Apoptosis of cerebellar granule cells induced by serum withdrawal, glutamate or beta-amyloid, is independent of Jun kinase or p38 mitogen activated protein kinase activation. Neuroscience letters. vol 250. issue 1. 1999-05-19. PMID:9696064.' |
it has been reported that in differentiated pc12 cells and neurons from the superior cervical ganglion and hippocampus, that the activation of the stress-activated protein kinases jun-n-terminal kinase (jnk) and/or p38 mitogen-activated protein (p38map) kinase is central to the induction of apoptosis by serum or neurotrophic factor withdrawal. |
1999-05-19 |
2023-08-12 |
Not clear |
| T Fukuda, H Wang, H Nakanishi, K Yamamoto, T Kosak. Novel non-apoptotic morphological changes in neurons of the mouse hippocampus following transient hypoxic-ischemia. Neuroscience research. vol 33. issue 1. 1999-05-17. PMID:10096471. |
a small population of dentate granule cells showed typical apoptotic ultrastructures that could be used as internal morphological standards of apoptosis, whereas most other hippocampal neurons consistently showed a distinct form of cellular disintegration. |
1999-05-17 |
2023-08-12 |
mouse |
| J K Lee, W S Hwang, Y D Lee, P L Ha. Dynamic expression of SEK1 suggests multiple roles of the gene during embryogenesis and in adult brain of mice. Brain research. Molecular brain research. vol 66. issue 1-2. 1999-05-13. PMID:10095085. |
the strongest expression of the sek1 was found in the ca3 region of hippocampus, the region being highly vulnerable to exitotoxicity-induced apoptosis in kainate-treated animal models. |
1999-05-13 |
2023-08-12 |
mouse |
| S Chen, N Mantei, L Dong, M Schachne. Prevention of neuronal cell death by neural adhesion molecules L1 and CHL1. Journal of neurobiology. vol 38. issue 3. 1999-05-07. PMID:10022583. |
cerebellar granule neurons of mouse and hippocampal neurons of rat embryo undergo apoptosis when cultured in serum-free medium. |
1999-05-07 |
2023-08-12 |
mouse |
| H Ozawa, S Shioda, K Dohi, H Matsumoto, H Mizushima, C J Zhou, H Funahashi, Y Nakai, S Nakajo, K Matsumot. Delayed neuronal cell death in the rat hippocampus is mediated by the mitogen-activated protein kinase signal transduction pathway. Neuroscience letters. vol 262. issue 1. 1999-05-06. PMID:10076872. |
transient global ischemia caused by 5 min of cardiac arrest induced delayed neuronal cell death (apoptosis) in the ca1 region of the rat hippocampus. |
1999-05-06 |
2023-08-12 |
rat |
| H Ozawa, S Shioda, K Dohi, H Matsumoto, H Mizushima, C J Zhou, H Funahashi, Y Nakai, S Nakajo, K Matsumot. Delayed neuronal cell death in the rat hippocampus is mediated by the mitogen-activated protein kinase signal transduction pathway. Neuroscience letters. vol 262. issue 1. 1999-05-06. PMID:10076872. |
to characterize the molecular mechanisms that regulate apoptosis in vivo, the contributions to cell death of mitogen-activated protein kinase family members were examined in the hippocampal region after brain ischemia-reperfusion. |
1999-05-06 |
2023-08-12 |
rat |
| M Tamatani, S Ogawa, G Nuñez, M Tohyam. Growth factors prevent changes in Bcl-2 and Bax expression and neuronal apoptosis induced by nitric oxide. Cell death and differentiation. vol 5. issue 10. 1999-05-06. PMID:10203697. |
both igf-1 and bfgf prevented apoptosis induced by no donors, sodium nitroprusside (snp) or 3-morpholinosydnonimin (sin-1) in hippocampal neuronal cultures. |
1999-05-06 |
2023-08-12 |
Not clear |
| Y Ishikawa, T Satoh, Y Enokido, C Nishio, T Ikeuchi, H Hatanak. Generation of reactive oxygen species, release of L-glutamate and activation of caspases are required for oxygen-induced apoptosis of embryonic hippocampal neurons in culture. Brain research. vol 824. issue 1. 1999-05-05. PMID:10095044. |
generation of reactive oxygen species, release of l-glutamate and activation of caspases are required for oxygen-induced apoptosis of embryonic hippocampal neurons in culture. |
1999-05-05 |
2023-08-12 |
Not clear |
| H G Wang, N Pathan, I M Ethell, S Krajewski, Y Yamaguchi, F Shibasaki, F McKeon, T Bobo, T F Franke, J C Ree. Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD. Science (New York, N.Y.). vol 284. issue 5412. 1999-05-04. PMID:10195903. |
in hippocampal neurons, l-glutamate, an inducer of ca2+ influx and calcineurin activation, triggered mitochondrial targeting of bad and apoptosis, which were both suppressible by coexpression of a dominant-inhibitory mutant of calcineurin or pharmacological inhibitors of this phosphatase. |
1999-05-04 |
2023-08-12 |
Not clear |
| K J Ivins, E T Bui, C W Cotma. Beta-amyloid induces local neurite degeneration in cultured hippocampal neurons: evidence for neuritic apoptosis. Neurobiology of disease. vol 5. issue 5. 1999-04-27. PMID:10069579. |
beta-amyloid induces local neurite degeneration in cultured hippocampal neurons: evidence for neuritic apoptosis. |
1999-04-27 |
2023-08-12 |
Not clear |
| b' K A Waters, B Meehan, J Q Huang, R A Gravel, J Michaud, A C\\xc3\\xb4t\\xc3\\xa. Neuronal apoptosis in sudden infant death syndrome. Pediatric research. vol 45. issue 2. 1999-04-16. PMID:10022585.' |
we found significant neuronal apoptosis in 79% of the sids cases: 55% of the cases positive in the hippocampus and 96% positive in the brainstem. |
1999-04-16 |
2023-08-12 |
Not clear |
| b' K A Waters, B Meehan, J Q Huang, R A Gravel, J Michaud, A C\\xc3\\xb4t\\xc3\\xa. Neuronal apoptosis in sudden infant death syndrome. Pediatric research. vol 45. issue 2. 1999-04-16. PMID:10022585.' |
whereas the distribution of apoptosis in the hippocampus was in hypoxia-sensitive subregions, the distribution in the brainstem was mostly in dorsal nuclei, including those involved with sensation in the face and position of the head (nucleus of the spinal trigeminal tract and vestibular nuclei). |
1999-04-16 |
2023-08-12 |
Not clear |
| b' K A Waters, B Meehan, J Q Huang, R A Gravel, J Michaud, A C\\xc3\\xb4t\\xc3\\xa. Neuronal apoptosis in sudden infant death syndrome. Pediatric research. vol 45. issue 2. 1999-04-16. PMID:10022585.' |
the control cases showed no significant apoptosis in the hippocampus and a mild degree in the brainstem in three cases. |
1999-04-16 |
2023-08-12 |
Not clear |
| E M Montgomery, M E Bardgett, B Lall, C A Csernansky, J G Csernansk. Delayed neuronal loss after administration of intracerebroventricular kainic acid to preweanling rats. Brain research. Developmental brain research. vol 112. issue 1. 1999-04-13. PMID:9974164. |
ka does not produce immediate neuronal loss in preweanling rats, the hippocampus is altered so that neuronal loss occurs after a delay, perhaps through apoptosis. |
1999-04-13 |
2023-08-12 |
rat |
| J S Braun, R Novak, K H Herzog, S M Bodner, J L Cleveland, E I Tuomane. Neuroprotection by a caspase inhibitor in acute bacterial meningitis. Nature medicine. vol 5. issue 3. 1999-04-13. PMID:10086385. |
hippocampal neuronal death was due to apoptosis derived from the inflammatory response in the cerebrospinal fluid. |
1999-04-13 |
2023-08-12 |
human |
| T Adayev, Y El-Sherif, M Barua, N J Penington, P Banerje. Agonist stimulation of the serotonin1A receptor causes suppression of anoxia-induced apoptosis via mitogen-activated protein kinase in neuronal HN2-5 cells. Journal of neurochemistry. vol 72. issue 4. 1999-04-13. PMID:10098853. |
using a hippocampal neuron-derived cell line (hn2-5) that is ca2+ channel-deficient, we demonstrate here that an alternative pathway is responsible for 5-ht1a-r-mediated protection of these cells from anoxia-triggered apoptosis, assessed by deoxynucleotidyl-transferase-mediated dutp nick end-labeling (tunel). |
1999-04-13 |
2023-08-12 |
Not clear |
| C D Albright, A Y Tsai, C B Friedrich, M H Mar, S H Zeise. Choline availability alters embryonic development of the hippocampus and septum in the rat. Brain research. Developmental brain research. vol 113. issue 1-2. 1999-04-07. PMID:10064869. |
in the present study, the effects of dietary choline on cell proliferation, migration, and apoptosis in neuronal progenitor cells in the hippocampus and septum were analyzed in fetal brains at different stages of embryonic development. |
1999-04-07 |
2023-08-12 |
rat |