| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P J Lucassen, G K Vollmann-Honsdorf, M Gleisberg, B Czéh, E R De Kloet, E Fuch. Chronic psychosocial stress differentially affects apoptosis in hippocampal subregions and cortex of the adult tree shrew. The European journal of neuroscience. vol 14. issue 1. 2001-09-27. PMID:11488960. |
we conclude that (i) low frequent apoptosis occurs throughout the adult tree shrew brain, and (ii) 28 days of chronic stress differentially affects its occurrence in distinct hippocampal subregions and entorhinal cortex. |
2001-09-27 |
2023-08-12 |
Not clear |
| N A Tatton, C Hagl, S Nandor, S Insolia, D Spielvogel, R B Griep. Apoptotic cell death in the hippocampus due to prolonged hypothermic circulatory arrest: comparison of cyclosporine A and cycloheximide on neuron survival. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery. vol 19. issue 6. 2001-09-20. PMID:11404126. |
to determine whether cyclosporine a (csa) or cycloheximide (chx) can reduce neuronal apoptosis in the hippocampus in a chronic animal model of hypothermic circulatory arrest (hca). |
2001-09-20 |
2023-08-12 |
Not clear |
| A Ravati, B Ahlemeyer, A Becker, S Klumpp, J Krieglstei. Preconditioning-induced neuroprotection is mediated by reactive oxygen species and activation of the transcription factor nuclear factor-kappaB. Journal of neurochemistry. vol 78. issue 4. 2001-09-20. PMID:11520911. |
preconditioning was performed by incubating mixed cultures of neurons and astrocytes from neonatal rat hippocampus with xanthine/xanthine oxidase or feso4 for 15 min followed by 24 h of recovery which protected the neurons against subsequent staurosporine-induced (200 nm, 24 h) apoptosis. |
2001-09-20 |
2023-08-12 |
rat |
| B Ahlemeyer, E Bauerbach, M Plath, M Steuber, C Heers, F Tegtmeier, J Krieglstei. Retinoic acid reduces apoptosis and oxidative stress by preservation of SOD protein level. Free radical biology & medicine. vol 30. issue 10. 2001-08-30. PMID:11369496. |
in this study, we determined the effect of ra on the mrna and protein levels of the cu-,zn-superoxide dismutase (sod-1) and mn-superoxide dismutase (sod-2) during staurosporine-induced apoptosis in primary cultures from neonatal rat hippocampus. |
2001-08-30 |
2023-08-12 |
rat |
| C L Yen, M H Mar, R B Meeker, A Fernandes, S H Zeise. Choline deficiency induces apoptosis in primary cultures of fetal neurons. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 15. issue 10. 2001-08-30. PMID:11481217. |
we now examine whether choline deprivation induces apoptosis in nondividing primary neuronal cultures of fetal rat cortex and hippocampus. |
2001-08-30 |
2023-08-12 |
rat |
| O Ghribi, D A DeWitt, M S Forbes, M M Herman, J Savor. Co-involvement of mitochondria and endoplasmic reticulum in regulation of apoptosis: changes in cytochrome c, Bcl-2 and Bax in the hippocampus of aluminum-treated rabbits. Brain research. vol 903. issue 1-2. 2001-08-16. PMID:11382389. |
co-involvement of mitochondria and endoplasmic reticulum in regulation of apoptosis: changes in cytochrome c, bcl-2 and bax in the hippocampus of aluminum-treated rabbits. |
2001-08-16 |
2023-08-12 |
human |
| M Runnerstam, F Bao, Y Huang, J Shi, E Gutierrez, A Hamberger, H A Hansson, D Viano, K Hagli. A new model for diffuse brain injury by rotational acceleration: II. Effects on extracellular glutamate, intracranial pressure, and neuronal apoptosis. Journal of neurotrauma. vol 18. issue 3. 2001-08-09. PMID:11284547. |
the initial response of the brain after rotational head injury involves brain edema after 24 h and an excitotoxic neuronal microenvironment in the first hour, which leads to extensive delayed neuronal cell death by apoptosis necrosis in the cerebral cortex, hippocampus and cerebellum. |
2001-08-09 |
2023-08-12 |
Not clear |
| T Trapp, L Oláh, I Hölker, M Besselmann, C Tiesler, K Maeda, K A Hossman. GTPase RhoB: an early predictor of neuronal death after transient focal ischemia in mice. Molecular and cellular neurosciences. vol 17. issue 5. 2001-08-09. PMID:11358485. |
apoptosis in a murine hippocampal cell line was also associated with an early increase in rhob protein. |
2001-08-09 |
2023-08-12 |
mouse |
| E Gozal, B W Row, A Schurr, D Goza. Developmental differences in cortical and hippocampal vulnerability to intermittent hypoxia in the rat. Neuroscience letters. vol 305. issue 3. 2001-08-02. PMID:11403939. |
intermittent hypoxia (ih) leads to increases in apoptosis in the cortex and hippocampus of the adult rat, peaking at 48 h of exposure. |
2001-08-02 |
2023-08-12 |
rat |
| E M Eves, C Skoczylas, K Yoshida, E S Alnemri, M R Rosne. FGF induces a switch in death receptor pathways in neuronal cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 14. 2001-07-26. PMID:11438575. |
fgf suppresses the fas death pathway but also induces apoptosis by activation of a tnfalpha death pathway in both h19-7 and hippocampal progenitor cells. |
2001-07-26 |
2023-08-12 |
rat |
| J Qiu, M R Grafe, S M Schmura, J N Glasgow, T A Kent, D K Rassin, J R Perez-Pol. Differential NF-kappa B regulation of bcl-x gene expression in hippocampus and basal forebrain in response to hypoxia. Journal of neuroscience research. vol 64. issue 3. 2001-07-19. PMID:11319766. |
we found that 1) hypoxia induced apoptosis in the hippocampus and basal forebrain; 2) the nf-kappa b dimers c-rel/p50 and p50/p50 bound to the bcl-x promoter nf-kappa b sequence (cs4) in the hippocampus, but only p50/p50 bound to the cs4 sequence in the basal forebrain and hypoxia-induced differential binding patterns of c-rel/p50 and p50/p50 correlated with the bcl-x expression pattern in the hippocampus; 3) the hypoxia-induced patterns of binding of c-rel/p50 to the bcl-x promoter cs4 sequence were different from those to the igg-kappa b enhancer sequence, whereas those of p50/p50 were similar to both sequences; 4) nuclear protein levels of c-rel, but not p50, correlated with the c-rel/p50 dna binding patterns to the bcl-x cs4 site; and 5) there were differential responses to hypoxia among the different nf-kappa b protein subunits. |
2001-07-19 |
2023-08-12 |
rat |
| J Qiu, M R Grafe, S M Schmura, J N Glasgow, T A Kent, D K Rassin, J R Perez-Pol. Differential NF-kappa B regulation of bcl-x gene expression in hippocampus and basal forebrain in response to hypoxia. Journal of neuroscience research. vol 64. issue 3. 2001-07-19. PMID:11319766. |
the absence of these regulating features in the basal forebrain may account for the early appearance of apoptosis in response to hypoxia as compared with that in hippocampus. |
2001-07-19 |
2023-08-12 |
rat |
| M J Kim, Y Kim, S A Kim, H J Lee, B K Choe, M Nam, B S Kim, J W Kim, S V Yim, C J Kim, J H Chun. Increases in cell proliferation and apoptosis in dentate gyrus of anorexia (anx/anx) mice. Neuroscience letters. vol 302. issue 2-3. 2001-07-12. PMID:11290399. |
in order to investigate changes in the occurrence of cell proliferation and apoptosis in the dentate gyrus of the hippocampus of anx/anx mice, 5-bromo-2'-deoxyuridine (brdu) immunohistochemistry and terminal deoxynucleotidyl transferase-mediated dutp nick end-labeling (tunel) assay were performed in this study. |
2001-07-12 |
2023-08-12 |
mouse |
| C Lu, W Fu, M P Mattso. Caspase-mediated suppression of glutamate (AMPA) receptor channel activity in hippocampal neurons in response to DNA damage promotes apoptosis and prevents necrosis: implications for neurological side effects of cancer therapy and neurodegenerative disorders. Neurobiology of disease. vol 8. issue 2. 2001-07-12. PMID:11300717. |
caspase-mediated suppression of glutamate (ampa) receptor channel activity in hippocampal neurons in response to dna damage promotes apoptosis and prevents necrosis: implications for neurological side effects of cancer therapy and neurodegenerative disorders. |
2001-07-12 |
2023-08-12 |
Not clear |
| L E Haynes, M R Griffiths, R E Hyde, D J Barber, I J Mitchel. Dexamethasone induces limited apoptosis and extensive sublethal damage to specific subregions of the striatum and hippocampus: implications for mood disorders. Neuroscience. vol 104. issue 1. 2001-07-12. PMID:11311531. |
dexamethasone induces limited apoptosis and extensive sublethal damage to specific subregions of the striatum and hippocampus: implications for mood disorders. |
2001-07-12 |
2023-08-12 |
human |
| L E Haynes, M R Griffiths, R E Hyde, D J Barber, I J Mitchel. Dexamethasone induces limited apoptosis and extensive sublethal damage to specific subregions of the striatum and hippocampus: implications for mood disorders. Neuroscience. vol 104. issue 1. 2001-07-12. PMID:11311531. |
subsequent quantitative analysis of silver/methenamine-stained sections confirmed that acute administration of dexamethasone induced apoptosis in the striatum and all regions of the hippocampus at doses as low as 0.7mg/kg. |
2001-07-12 |
2023-08-12 |
human |
| L E Haynes, M R Griffiths, R E Hyde, D J Barber, I J Mitchel. Dexamethasone induces limited apoptosis and extensive sublethal damage to specific subregions of the striatum and hippocampus: implications for mood disorders. Neuroscience. vol 104. issue 1. 2001-07-12. PMID:11311531. |
the levels of dexamethasone-induced striatal and hippocampal apoptosis were attenuated by pretreatment with the corticosteroid receptor antagonist ru38486 (mifepristone), which implies that the cell death was mediated by a corticosteroid receptor-dependent process. |
2001-07-12 |
2023-08-12 |
human |
| A Yamaguchi, M Tamatani, H Matsuzaki, K Namikawa, H Kiyama, M P Vitek, N Mitsuda, M Tohyam. Akt activation protects hippocampal neurons from apoptosis by inhibiting transcriptional activity of p53. The Journal of biological chemistry. vol 276. issue 7. 2001-06-28. PMID:11054421. |
akt activation protects hippocampal neurons from apoptosis by inhibiting transcriptional activity of p53. |
2001-06-28 |
2023-08-12 |
Not clear |
| A Yamaguchi, M Tamatani, H Matsuzaki, K Namikawa, H Kiyama, M P Vitek, N Mitsuda, M Tohyam. Akt activation protects hippocampal neurons from apoptosis by inhibiting transcriptional activity of p53. The Journal of biological chemistry. vol 276. issue 7. 2001-06-28. PMID:11054421. |
we eliminated p53 by employing p53-deficient neurons and increased p53 by infection with recombinant adenovirus capable of transducing p53 expression, and we now show that p53 is implicated in the apoptosis induced by hypoxia or no treatments of primary cultured hippocampal neurons. |
2001-06-28 |
2023-08-12 |
Not clear |
| C Culmsee, S Bondada, M P Mattso. Hippocampal neurons of mice deficient in DNA-dependent protein kinase exhibit increased vulnerability to DNA damage, oxidative stress and excitotoxicity. Brain research. Molecular brain research. vol 87. issue 2. 2001-06-28. PMID:11245929. |
we now report that cultured hippocampal neurons from severe combined immunodeficient (scid) mice which lack dna-pk activity are hypersensitive to apoptosis induced by exposure to topoisomerase inhibitors, amyloid beta peptide (a beta) and glutamate. |
2001-06-28 |
2023-08-12 |
mouse |