| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yoshitaka Tatebayashi, Moon H Lee, Liang Li, Khalid Iqbal, Inge Grundke-Iqba. The dentate gyrus neurogenesis: a therapeutic target for Alzheimer's disease. Acta neuropathologica. vol 105. issue 3. 2003-04-23. PMID:12557008. |
cerebrolysin, a neurotrophic drug which has been shown to improve cognition and mood of ad patients, was found to increase neuron-like differentiated adult rat hippocampal progenitors in culture both by reducing apoptosis and by counteracting the fgf-2-induced polarity shift. |
2003-04-23 |
2023-08-12 |
human |
| Madhuri Roy, Robert M Sapolsk. The exacerbation of hippocampal excitotoxicity by glucocorticoids is not mediated by apoptosis. Neuroendocrinology. vol 77. issue 1. 2003-04-23. PMID:12624538. |
the exacerbation of hippocampal excitotoxicity by glucocorticoids is not mediated by apoptosis. |
2003-04-23 |
2023-08-12 |
Not clear |
| Madhuri Roy, Robert M Sapolsk. The exacerbation of hippocampal excitotoxicity by glucocorticoids is not mediated by apoptosis. Neuroendocrinology. vol 77. issue 1. 2003-04-23. PMID:12624538. |
in this study we investigate whether the gc-mediated exacerbation of hippocampal excitotoxicity in culture involves apoptosis. |
2003-04-23 |
2023-08-12 |
Not clear |
| Madhuri Roy, Robert M Sapolsk. The exacerbation of hippocampal excitotoxicity by glucocorticoids is not mediated by apoptosis. Neuroendocrinology. vol 77. issue 1. 2003-04-23. PMID:12624538. |
specifically, we show that while the magnitude of hippocampal neuron death caused by the excitotoxin kainic acid is indeed worsened in the presence of gcs, there is no evidence of increased markers of apoptosis. |
2003-04-23 |
2023-08-12 |
Not clear |
| Madhuri Roy, Robert M Sapolsk. The exacerbation of hippocampal excitotoxicity by glucocorticoids is not mediated by apoptosis. Neuroendocrinology. vol 77. issue 1. 2003-04-23. PMID:12624538. |
thus, gcs appear to augment excitotoxic death in hippocampal neurons without augmenting the occurrence of apoptosis. |
2003-04-23 |
2023-08-12 |
Not clear |
| Hae Sook Noh, Yoon Sook Kim, Hee Po Lee, Ki Myung Chung, Dong Wook Kim, Sang Soo Kang, Gyeong Jae Cho, Wan Sung Cho. The protective effect of a ketogenic diet on kainic acid-induced hippocampal cell death in the male ICR mice. Epilepsy research. vol 53. issue 1-2. 2003-04-09. PMID:12576173. |
these findings indicate that kd has an antiepileptic effect via a neuroprotective action that involves the inhibition of caspase-3-mediated apoptosis of hippocampal neurons. |
2003-04-09 |
2023-08-12 |
mouse |
| Catherine E Adams, Ron S Broide, Yiling Chen, Ursula H Winzer-Serhan, Theodore A Henderson, Frances M Leslie, Robert Freedma. Development of the alpha7 nicotinic cholinergic receptor in rat hippocampal formation. Brain research. Developmental brain research. vol 139. issue 2. 2003-04-02. PMID:12480132. |
the early appearance and complex, prolonged pattern of development of the alpha7 receptor suggest that it may influence processes as diverse as cell migration, dendritic elaboration and apoptosis during hippocampal maturation. |
2003-04-02 |
2023-08-12 |
rat |
| Hongxin Dong, Cynthia A Csernansky, Brian Goico, John G Csernansk. Hippocampal neurogenesis follows kainic acid-induced apoptosis in neonatal rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 5. 2003-03-24. PMID:12629178. |
hippocampal neurogenesis follows kainic acid-induced apoptosis in neonatal rats. |
2003-03-24 |
2023-08-12 |
rat |
| Xiaoqin Ye, Isao Ishii, Marcy A Kingsbury, Jerold Chu. Lysophosphatidic acid as a novel cell survival/apoptotic factor. Biochimica et biophysica acta. vol 1585. issue 2-3. 2003-03-18. PMID:12531543. |
paradoxically, lpa also induces apoptosis in certain cells, such as myeloid progenitor cells, hippocampal neurons, and pc12 cells, in which the activation of the rho-dependent pathways and caspase cascades has been implicated. |
2003-03-18 |
2023-08-12 |
Not clear |
| D A Cottrell, G M Borthwick, M A Johnson, P G Ince, D M Turnbul. The role of cytochrome c oxidase deficient hippocampal neurones in Alzheimer's disease. Neuropathology and applied neurobiology. vol 28. issue 5. 2003-03-12. PMID:12366820. |
cox-deficient, succinate dehydrogenase-positive hippocampal neurones indicative of high mtdna mutation load do not appear to be prone to apoptosis or to directly participate in the over production of tau or beta-amyloid. |
2003-03-12 |
2023-08-12 |
Not clear |
| Quanguang Zhang, Guangyi Zhang, Fanjie Meng, Hui Tia. Biphasic activation of apoptosis signal-regulating kinase 1-stress-activated protein kinase 1-c-Jun N-terminal protein kinase pathway is selectively mediated by Ca2+-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors involving oxidative stress following brain ischemia in rat hippocampus. Neuroscience letters. vol 337. issue 1. 2003-03-12. PMID:12524169. |
biphasic activation of apoptosis signal-regulating kinase 1-stress-activated protein kinase 1-c-jun n-terminal protein kinase pathway is selectively mediated by ca2+-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors involving oxidative stress following brain ischemia in rat hippocampus. |
2003-03-12 |
2023-08-12 |
rat |
| Devin S Gary, Ollivier Milhavet, Simonetta Camandola, Mark P Mattso. Essential role for integrin linked kinase in Akt-mediated integrin survival signaling in hippocampal neurons. Journal of neurochemistry. vol 84. issue 4. 2003-03-05. PMID:12562530. |
we report that integrin signaling prevents apoptosis of embryonic hippocampal neurons by a mechanism involving integrin-linked kinase (ilk) that activates akt kinase. |
2003-03-05 |
2023-08-12 |
Not clear |
| Devin S Gary, Ollivier Milhavet, Simonetta Camandola, Mark P Mattso. Essential role for integrin linked kinase in Akt-mediated integrin survival signaling in hippocampal neurons. Journal of neurochemistry. vol 84. issue 4. 2003-03-05. PMID:12562530. |
activation of integrins using a peptide containing the amino acid sequence eikllis derived from the alpha chain of laminin protected hippocampal neurons from apoptosis induced by glutamate or staurosporine, and increased akt activity in a beta1 integrin-dependent manner. |
2003-03-05 |
2023-08-12 |
Not clear |
| J J Miguel-Hidalgo, X A Alvarez, R Cacabelos, G Quac. Neuroprotection by memantine against neurodegeneration induced by beta-amyloid(1-40). Brain research. vol 958. issue 1. 2003-02-25. PMID:12468047. |
abeta(1-40), but not water, injections into hippocampus led to neuronal loss in the ca1 subfield, evidence of widespread apoptosis, and astrocytic and microglial activation and hypertrophy. |
2003-02-25 |
2023-08-12 |
rat |
| Wenshuai Wan, Paolo B DePetrill. Ritonavir protects hippocampal neurons against oxidative stress-induced apoptosis. Neurotoxicology. vol 23. issue 3. 2003-02-21. PMID:12387358. |
ritonavir protects hippocampal neurons against oxidative stress-induced apoptosis. |
2003-02-21 |
2023-08-12 |
Not clear |
| Wenshuai Wan, Paolo B DePetrill. Ritonavir protects hippocampal neurons against oxidative stress-induced apoptosis. Neurotoxicology. vol 23. issue 3. 2003-02-21. PMID:12387358. |
the present study demonstrated that the hydrophobic hiv protease inhibitor, ritonavir inhibited hne-mediated apoptosis in hippocampal primary neurons. |
2003-02-21 |
2023-08-12 |
Not clear |
| Roland Nau, Sabine Haase, Stephanie Bunkowski, Wolfgang Brüc. Neuronal apoptosis in the dentate gyrus in humans with subarachnoid hemorrhage and cerebral hypoxia. Brain pathology (Zurich, Switzerland). vol 12. issue 3. 2003-02-14. PMID:12146801. |
apoptosis appears to be the predominant mechanism of death in dentate granule cells irrespective of the underlying disease, whereas neuronal death in the hippocampus generally is of necrotic morphology. |
2003-02-14 |
2023-08-12 |
Not clear |
| Canan Türkyilmaz, Zafer Türkyilmaz, Yildiz Atalay, Figen Söylemezoglu, Bülent Celasu. Magnesium pre-treatment reduces neuronal apoptosis in newborn rats in hypoxia-ischemia. Brain research. vol 955. issue 1-2. 2003-01-31. PMID:12419529. |
the right apoptosis index of the hippocampus in magnesium pre-treated rats (mean+/-s.d. |
2003-01-31 |
2023-08-12 |
human |
| D Perkins, E F R Pereira, L Aurelia. The herpes simplex virus type 2 R1 protein kinase (ICP10 PK) functions as a dominant regulator of apoptosis in hippocampal neurons involving activation of the ERK survival pathway and upregulation of the antiapoptotic protein Bag-1. Journal of virology. vol 77. issue 2. 2003-01-22. PMID:12502846. |
the herpes simplex virus type 2 r1 protein kinase (icp10 pk) functions as a dominant regulator of apoptosis in hippocampal neurons involving activation of the erk survival pathway and upregulation of the antiapoptotic protein bag-1. |
2003-01-22 |
2023-08-12 |
Not clear |
| D Perkins, E F R Pereira, L Aurelia. The herpes simplex virus type 2 R1 protein kinase (ICP10 PK) functions as a dominant regulator of apoptosis in hippocampal neurons involving activation of the ERK survival pathway and upregulation of the antiapoptotic protein Bag-1. Journal of virology. vol 77. issue 2. 2003-01-22. PMID:12502846. |
we have recently shown that the protein kinase activity of the large subunit of the hsv-2 ribonucleotide reductase (r1) protein (icp10 pk) blocks apoptosis in cultured hippocampal neurons by activating the extracellular signal-regulated kinase (erk) survival pathway (perkins et al., j. virol. |
2003-01-22 |
2023-08-12 |
Not clear |