| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mark A Lovell, Chengsong Xie, Shuling Xiong, William R Markesber. Wilms' tumor suppressor (WT1) is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer's disease. Brain research. vol 983. issue 1-2. 2003-11-28. PMID:12914969. |
laser confocal microscopy of hippocampal neuron cultures undergoing apoptosis induced by amyloid beta peptide (abeta) or staurosporine demonstrated significant time-dependent elevations of wt1 correlating with increased levels of apoptosis. |
2003-11-28 |
2023-08-12 |
Not clear |
| Honghui Chen, Shenggang Sun, Yuanwu Mei, Changqin Liu, Anqiu Liu, Etang Ton. The effect of beta-amyloid on neurons and the influence of glucocorticoid and age on such effect. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 22. issue 3. 2003-11-26. PMID:12658818. |
to explore the relationship between beta-amyloid (a beta) and the pathogenesis of alzheimer disease (ad), after injection of beta-amyloid into the rat brain, the apoptosis of nerve cells and acetylcholine (ach) content in rat hippocampus were examined by employing tunel technique and base hydroxylamine colorimetry respectively. |
2003-11-26 |
2023-08-12 |
rat |
| Honghui Chen, Shenggang Sun, Yuanwu Mei, Changqin Liu, Anqiu Liu, Etang Ton. The effect of beta-amyloid on neurons and the influence of glucocorticoid and age on such effect. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 22. issue 3. 2003-11-26. PMID:12658818. |
a beta peptide could strongly induce the apoptosis of neurons in hippocampus, cortex and striate body (p < 0.05 or p < 0.01). |
2003-11-26 |
2023-08-12 |
rat |
| Olena Shakhman, Matthias Herkert, Christine Rose, Andreas Humeny, Cord-Michael Becke. Induction by beta-bungarotoxin of apoptosis in cultured hippocampal neurons is mediated by Ca(2+)-dependent formation of reactive oxygen species. Journal of neurochemistry. vol 87. issue 3. 2003-11-24. PMID:14535943. |
induction by beta-bungarotoxin of apoptosis in cultured hippocampal neurons is mediated by ca(2+)-dependent formation of reactive oxygen species. |
2003-11-24 |
2023-08-12 |
rat |
| Olena Shakhman, Matthias Herkert, Christine Rose, Andreas Humeny, Cord-Michael Becke. Induction by beta-bungarotoxin of apoptosis in cultured hippocampal neurons is mediated by Ca(2+)-dependent formation of reactive oxygen species. Journal of neurochemistry. vol 87. issue 3. 2003-11-24. PMID:14535943. |
the component of the venom of the taiwanese banded krait bungarus multicinctus, beta-bungarotoxin (beta-butx), acts as an extremely potent inducer of neuronal apoptosis when applied to rat hippocampal cultures. |
2003-11-24 |
2023-08-12 |
rat |
| Li Yang, Kyoko Omori, Koichiro Omori, Hitomi Otani, Junko Suzukawa, Chiyoko Inagak. GABAC receptor agonist suppressed ammonia-induced apoptosis in cultured rat hippocampal neurons by restoring phosphorylated BAD level. Journal of neurochemistry. vol 87. issue 3. 2003-11-24. PMID:14535961. |
gabac receptor agonist suppressed ammonia-induced apoptosis in cultured rat hippocampal neurons by restoring phosphorylated bad level. |
2003-11-24 |
2023-08-12 |
rat |
| Li Yang, Kyoko Omori, Koichiro Omori, Hitomi Otani, Junko Suzukawa, Chiyoko Inagak. GABAC receptor agonist suppressed ammonia-induced apoptosis in cultured rat hippocampal neurons by restoring phosphorylated BAD level. Journal of neurochemistry. vol 87. issue 3. 2003-11-24. PMID:14535961. |
ammonia-induced apoptosis and its prevention by gabac receptor stimulation were examined using primary cultured rat hippocampal neurons. |
2003-11-24 |
2023-08-12 |
rat |
| Matthew J During, Lei Cao, David S Zuzga, Jeremy S Francis, Helen L Fitzsimons, Xiangyang Jiao, Ross J Bland, Matthias Klugmann, William A Banks, Daniel J Drucker, Colin N Hail. Glucagon-like peptide-1 receptor is involved in learning and neuroprotection. Nature medicine. vol 9. issue 9. 2003-11-20. PMID:12925848. |
systemic administration of [ser(2)]exendin(1-9) in wild-type animals prevents kainate-induced apoptosis of hippocampal neurons. |
2003-11-20 |
2023-08-12 |
mouse |
| Inger Lauritzen, Marc Zanzouri, Eric Honoré, Fabrice Duprat, Markus U Ehrengruber, Michel Lazdunski, Amanda J Pate. K+-dependent cerebellar granule neuron apoptosis. Role of task leak K+ channels. The Journal of biological chemistry. vol 278. issue 34. 2003-10-29. PMID:12783883. |
rat mature cerebellar granule, unlike hippocampal neurons, die by apoptosis when cultured in a medium containing a physiological concentration of k+ but survive under high external k+ concentrations. |
2003-10-29 |
2023-08-12 |
rat |
| B Ahlemeyer, J Krieglstei. Pharmacological studies supporting the therapeutic use of Ginkgo biloba extract for Alzheimer's disease. Pharmacopsychiatry. vol 36 Suppl 1. 2003-10-15. PMID:13130383. |
bilobalide (100 microm) rescued cultured rat hippocampal neurons from apoptosis caused by serum deprivation (24h), whereas ginkgolide b (100 microm) and bilobalide (100 microm) reduced apoptotic damage induced by staurosporine (300 nm, 24h). |
2003-10-15 |
2023-08-12 |
mouse |
| Myoung-Hwa Lee, Hong Kim, Sung-Soo Kim, Taeck-Hyun Lee, Baek-Vin Lim, Hyun-Kyung Chang, Mi-Hyeon Jang, Min-Chul Shin, Mal-Soon Shin, Chang-Ju Ki. Treadmill exercise suppresses ischemia-induced increment in apoptosis and cell proliferation in hippocampal dentate gyrus of gerbils. Life sciences. vol 73. issue 19. 2003-09-30. PMID:12954454. |
treadmill exercise suppresses ischemia-induced increment in apoptosis and cell proliferation in hippocampal dentate gyrus of gerbils. |
2003-09-30 |
2023-08-12 |
Not clear |
| Myoung-Hwa Lee, Hong Kim, Sung-Soo Kim, Taeck-Hyun Lee, Baek-Vin Lim, Hyun-Kyung Chang, Mi-Hyeon Jang, Min-Chul Shin, Mal-Soon Shin, Chang-Ju Ki. Treadmill exercise suppresses ischemia-induced increment in apoptosis and cell proliferation in hippocampal dentate gyrus of gerbils. Life sciences. vol 73. issue 19. 2003-09-30. PMID:12954454. |
in the present study, the effects of treadmill exercise on apoptosis and cell proliferation in the hippocampal dentate gyrus following transient global ischemia in gerbils were investigated using terminal deoxynucleotidyl transferase-mediated dutp nick end labeling (tunel) assay and immunohistochemistry for caspase-3 and 5-bromo-2'-deoxyuridine (brdu). |
2003-09-30 |
2023-08-12 |
Not clear |
| Myoung-Hwa Lee, Hong Kim, Sung-Soo Kim, Taeck-Hyun Lee, Baek-Vin Lim, Hyun-Kyung Chang, Mi-Hyeon Jang, Min-Chul Shin, Mal-Soon Shin, Chang-Ju Ki. Treadmill exercise suppresses ischemia-induced increment in apoptosis and cell proliferation in hippocampal dentate gyrus of gerbils. Life sciences. vol 73. issue 19. 2003-09-30. PMID:12954454. |
it was shown that apoptotic cell death and cell proliferation in the hippocampal dentate gyrus were significantly increased following transient global ischemia in gerbils and that treadmill exercise suppressed the ischemia-induced increase in apoptosis and cell proliferation in the dentate gyrus. |
2003-09-30 |
2023-08-12 |
Not clear |
| Jongseok Lee, Dongwook Son, Pyeongjae Lee, Sun-Yeou Kim, Hocheol Kim, Chang-Ju Kim, Eunhee Li. Alkaloid fraction of Uncaria rhynchophylla protects against N-methyl-D-aspartate-induced apoptosis in rat hippocampal slices. Neuroscience letters. vol 348. issue 1. 2003-09-12. PMID:12893423. |
alkaloid fraction of uncaria rhynchophylla protects against n-methyl-d-aspartate-induced apoptosis in rat hippocampal slices. |
2003-09-12 |
2023-08-12 |
rat |
| Jongseok Lee, Dongwook Son, Pyeongjae Lee, Sun-Yeou Kim, Hocheol Kim, Chang-Ju Kim, Eunhee Li. Alkaloid fraction of Uncaria rhynchophylla protects against N-methyl-D-aspartate-induced apoptosis in rat hippocampal slices. Neuroscience letters. vol 348. issue 1. 2003-09-12. PMID:12893423. |
in the present study, the alkaloid fraction of u. rhynchophylla was shown to have a protective property against nmda-induced cytotoxicity by suppressing the nmda-induced apoptosis in rat hippocampal slices. |
2003-09-12 |
2023-08-12 |
rat |
| Su-Jin Yun, Doo-Jae Lee, Mi-Ok Kim, Bomi Jung, Sung Ok Kim, Nak Won Sohn, Eunjoo H Le. Reduction but not cleavage of poly(ADP-ribose) polymerase during stress-mediated cell death in the rat hippocampus. Neuroreport. vol 14. issue 7. 2003-09-02. PMID:12802178. |
we analyzed the molecular events related to apoptosis in the hippocampus of rats exposed to immobilization stress. |
2003-09-02 |
2023-08-12 |
rat |
| Muhammad Zafrullah Khan, Renato Brandimarti, Brian Joseph Musser, Danielle Marie Resue, Alessandro Fatatis, Olimpia Meucc. The chemokine receptor CXCR4 regulates cell-cycle proteins in neurons. Journal of neurovirology. vol 9. issue 3. 2003-08-29. PMID:12775414. |
the data indicate that changes in the nuclear and cytosolic levels of rb--which result in the functional loss of this protein--are associated with apoptosis in hippocampal or cerebellar granule neurons and in cell lines. |
2003-08-29 |
2023-08-12 |
human |
| Linda K Friedman, Jana Velísková, Jaspreet Kaur, Bonaventure W Magrys, Hongguang Li. GluR2(B) knockdown accelerates CA3 injury after kainate seizures. Journal of neuropathology and experimental neurology. vol 62. issue 7. 2003-08-22. PMID:12901700. |
therefore, hippocampal deprivation of glur2(b) subunits is insufficient to induce cell death in mature animals but may accelerate the already known ca3/hilar lesion, possibly by triggering apoptosis within ca3 neurons. |
2003-08-22 |
2023-08-12 |
rat |
| Tatyana Adayev, Indrani Ray, Rachna Sondhi, Tomasz Sobocki, Probal Banerje. The G protein-coupled 5-HT1A receptor causes suppression of caspase-3 through MAPK and protein kinase Calpha. Biochimica et biophysica acta. vol 1640. issue 1. 2003-08-21. PMID:12676358. |
the 5-ht(1a) agonist 8-hydroxy-2 (di-n-propylamino) tetralin (8-oh-dpat) causes inhibition of caspase-3 and apoptosis via the extracellular signal-regulated kinases (erk1/2) in hippocampal hn2-5 cells. |
2003-08-21 |
2023-08-12 |
Not clear |
| Shinichiro Mizumatsu, Michelle L Monje, Duncan R Morhardt, Radoslaw Rola, Theo D Palmer, John R Fik. Extreme sensitivity of adult neurogenesis to low doses of X-irradiation. Cancer research. vol 63. issue 14. 2003-08-13. PMID:12874001. |
young adult male c57bl mice received whole brain irradiation, and 6-48 h later, hippocampal tissue was assessed using immunohistochemistry for detection of apoptosis and numbers of proliferating cells and immature neurons. |
2003-08-13 |
2023-08-12 |
mouse |