| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sthephen L Leib, Chris Heimgartner, Yoeng-Delphine Bifrare, Jutta M Loeffler, Martin G Täaube. Dexamethasone aggravates hippocampal apoptosis and learning deficiency in pneumococcal meningitis in infant rats. Pediatric research. vol 54. issue 3. 2004-07-09. PMID:12788989. |
neuronal apoptosis in the hippocampal dentate gyrus 34 h after infection was significantly aggravated by dexamethasone treatment compared with vehicle controls (p = 0.02). |
2004-07-09 |
2023-08-12 |
rat |
| Hajnalka Abraham, Carlos Gustavo Pérez-García, Gundela Meye. p73 and Reelin in Cajal-Retzius cells of the developing human hippocampal formation. Cerebral cortex (New York, N.Y. : 1991). vol 14. issue 5. 2004-07-09. PMID:15054064. |
in the fetal human hippocampus, cajal-retzius (cr) cells coexpress p73, a p53-family member involved in cell survival and apoptosis, and the glycoprotein reelin, crucial for radial migration. |
2004-07-09 |
2023-08-12 |
human |
| Christian Gianinazzi, Denis Grandgirard, Franziska Simon, Hans Imboden, Philipp Joss, Martin G Täuber, Stephen L Lei. Apoptosis of hippocampal neurons in organotypic slice culture models: direct effect of bacteria revisited. Journal of neuropathology and experimental neurology. vol 63. issue 6. 2004-07-08. PMID:15217089. |
apoptosis of hippocampal neurons in organotypic slice culture models: direct effect of bacteria revisited. |
2004-07-08 |
2023-08-12 |
rat |
| Anna Kolarova, Ralph Ringer, Martin G Täuber, Stephen L Lei. Blockade of NMDA receptor subtype NR2B prevents seizures but not apoptosis of dentate gyrus neurons in bacterial meningitis in infant rats. BMC neuroscience. vol 4. 2004-07-07. PMID:13129439. |
here we evaluated the effect of ro 25-6981 on hippocampal neuronal apoptosis in an infant rat model of meningitis due to streptococcus pneumoniae. |
2004-07-07 |
2023-08-12 |
rat |
| Marina Ioudina, Etsuro Uemura, Heather West Greenle. Glucose insufficiency alters neuronal viability and increases susceptibility to glutamate toxicity. Brain research. vol 1004. issue 1-2. 2004-06-24. PMID:15033434. |
we investigated the effect of a restricted supply of glucose on neuronal vulnerability to glutamate by assaying cellular atp levels (cellular energy production), 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (mtt) reduction (mitochondrial function), lactate dehydrogenase (ldh) release (cellular viability) and activation of caspase-3 (apoptosis) in rat hippocampal neurons cultured in media (1.7, 5 and 25 mm glucose) with or without 100 microm glutamate. |
2004-06-24 |
2023-08-12 |
rat |
| Katsunori Iwasaki, Kenichi Mishima, Nobuaki Egashira, Izzettin Hatip Al-Khatib, Daisuke Ishibashi, Keiichi Irie, Hirotoshi Kobayashi, Takashi Egawa, Michihiro Fujiwar. Effect of nilvadipine on the cerebral ischemia-induced impairment of spatial memory and hippocampal apoptosis in rats. Journal of pharmacological sciences. vol 93. issue 2. 2004-06-18. PMID:14578587. |
effect of nilvadipine on the cerebral ischemia-induced impairment of spatial memory and hippocampal apoptosis in rats. |
2004-06-18 |
2023-08-12 |
rat |
| Katsunori Iwasaki, Kenichi Mishima, Nobuaki Egashira, Izzettin Hatip Al-Khatib, Daisuke Ishibashi, Keiichi Irie, Hirotoshi Kobayashi, Takashi Egawa, Michihiro Fujiwar. Effect of nilvadipine on the cerebral ischemia-induced impairment of spatial memory and hippocampal apoptosis in rats. Journal of pharmacological sciences. vol 93. issue 2. 2004-06-18. PMID:14578587. |
on the other hand, repeated cerebral ischemia (10 min ischemia x 2, 1 h interval) impaired spatial memory and induced hippocampal apoptosis 7 days after the final occlusion/reperfusion. |
2004-06-18 |
2023-08-12 |
rat |
| Katsunori Iwasaki, Kenichi Mishima, Nobuaki Egashira, Izzettin Hatip Al-Khatib, Daisuke Ishibashi, Keiichi Irie, Hirotoshi Kobayashi, Takashi Egawa, Michihiro Fujiwar. Effect of nilvadipine on the cerebral ischemia-induced impairment of spatial memory and hippocampal apoptosis in rats. Journal of pharmacological sciences. vol 93. issue 2. 2004-06-18. PMID:14578587. |
however, mrna expression of the apoptosis-related early oncogene bax and cpp 32 (caspase-3) was observed after 24 h. in these rats, nilvadipine, but not amlodipine, significantly improved memory, concomitantly decreased hippocampal apoptosis, and suppressed both bax and cpp 32 expression. |
2004-06-18 |
2023-08-12 |
rat |
| Katsunori Iwasaki, Kenichi Mishima, Nobuaki Egashira, Izzettin Hatip Al-Khatib, Daisuke Ishibashi, Keiichi Irie, Hirotoshi Kobayashi, Takashi Egawa, Michihiro Fujiwar. Effect of nilvadipine on the cerebral ischemia-induced impairment of spatial memory and hippocampal apoptosis in rats. Journal of pharmacological sciences. vol 93. issue 2. 2004-06-18. PMID:14578587. |
these results suggest that nilvadipine improved the memory impairment in repeated ischemia by reducing bax and cpp 32 expression and suppressing the induction of apoptosis in the hippocampus. |
2004-06-18 |
2023-08-12 |
rat |
| Paolo G Marciano, Julia Brettschneider, Elisabetta Manduchi, Jason E Davis, Scott Eastman, Ramesh Raghupathi, Kathryn E Saatman, Terence P Speed, Christian J Stoeckert, James H Eberwine, Tracy K McIntos. Neuron-specific mRNA complexity responses during hippocampal apoptosis after traumatic brain injury. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 12. 2004-06-10. PMID:15044525. |
neuron-specific mrna complexity responses during hippocampal apoptosis after traumatic brain injury. |
2004-06-10 |
2023-08-12 |
mouse |
| Seiji Shioda, Hirokazu Ohtaki, Ryusuke Suzuki, Tomoya Nakamachi, Fumiko Takenoya, Kenji Dohi, Shigeo Nakaj. [Prevention of delayed neuronal cell death by PACAP and its molecular mechanism]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 123. issue 4. 2004-06-10. PMID:15056939. |
ischemic delayed neuronal cell death (apoptosis) in the hippocampus is prevented by pacap. |
2004-06-10 |
2023-08-12 |
mouse |
| Kan Liu, Andrew J Paterson, Fengxue Zhang, Joanne McAndrew, Ken-Ichiro Fukuchi, J Michael Wyss, Ling Peng, Yong Hu, Jeffrey E Kudlo. Accumulation of protein O-GlcNAc modification inhibits proteasomes in the brain and coincides with neuronal apoptosis in brain areas with high O-GlcNAc metabolism. Journal of neurochemistry. vol 89. issue 4. 2004-06-04. PMID:15140202. |
later, some hippocampal cells, but not purkinje cells, undergo apoptosis. |
2004-06-04 |
2023-08-12 |
Not clear |
| Li Yang, Kyoko Omori, Junko Suzukawa, Chiyoko Inagak. Calcineurin-mediated BAD Ser155 dephosphorylation in ammonia-induced apoptosis of cultured rat hippocampal neurons. Neuroscience letters. vol 357. issue 1. 2004-06-03. PMID:15036616. |
calcineurin-mediated bad ser155 dephosphorylation in ammonia-induced apoptosis of cultured rat hippocampal neurons. |
2004-06-03 |
2023-08-12 |
rat |
| Li Yang, Kyoko Omori, Junko Suzukawa, Chiyoko Inagak. Calcineurin-mediated BAD Ser155 dephosphorylation in ammonia-induced apoptosis of cultured rat hippocampal neurons. Neuroscience letters. vol 357. issue 1. 2004-06-03. PMID:15036616. |
we previously reported that ammonia induced apoptosis in cultured rat hippocampal neurons with moderate increases in the intracellular calcium concentration and decreases in phospho-bad levels. |
2004-06-03 |
2023-08-12 |
rat |
| Sarah M Richardson-Burns, Kenneth L Tyle. Regional differences in viral growth and central nervous system injury correlate with apoptosis. Journal of virology. vol 78. issue 10. 2004-05-27. PMID:15113925. |
vark-induced apoptosis was limited to the hippocampus in vivo, and in vitro both viruses induced apoptosis equally in mhc but vark induced significantly less apoptosis than t3d in mcc. |
2004-05-27 |
2023-08-12 |
mouse |
| Laura Korhonen, Ulla Näpänkangas, Håkan Steen, Yuming Chen, Rodrigo Martinez, Dan Lindhol. Differential regulation of X-chromosome-linked inhibitor of apoptosis protein (XIAP) and caspase-3 by NMDA in developing hippocampal neurons; involvement of the mitochondrial pathway in NMDA-mediated neuronal survival. Experimental cell research. vol 295. issue 2. 2004-05-20. PMID:15093730. |
differential regulation of x-chromosome-linked inhibitor of apoptosis protein (xiap) and caspase-3 by nmda in developing hippocampal neurons; involvement of the mitochondrial pathway in nmda-mediated neuronal survival. |
2004-05-20 |
2023-08-12 |
Not clear |
| Laura Korhonen, Ulla Näpänkangas, Håkan Steen, Yuming Chen, Rodrigo Martinez, Dan Lindhol. Differential regulation of X-chromosome-linked inhibitor of apoptosis protein (XIAP) and caspase-3 by NMDA in developing hippocampal neurons; involvement of the mitochondrial pathway in NMDA-mediated neuronal survival. Experimental cell research. vol 295. issue 2. 2004-05-20. PMID:15093730. |
here, we show that treatment with low concentrations of nmda upregulates the neuroprotective molecule, x-chromosome-linked inhibitor of apoptosis protein (xiap) in cultured hippocampal neurons at the post-transcriptional level. |
2004-05-20 |
2023-08-12 |
Not clear |
| Paul J Lucassen, Eberhard Fuchs, Boldizsár Czé. Antidepressant treatment with tianeptine reduces apoptosis in the hippocampal dentate gyrus and temporal cortex. Biological psychiatry. vol 55. issue 8. 2004-05-17. PMID:15050859. |
antidepressant treatment with tianeptine reduces apoptosis in the hippocampal dentate gyrus and temporal cortex. |
2004-05-17 |
2023-08-12 |
Not clear |
| Hyun-Taeg Shin, Seok-Hee Chung, Jong-Soo Lee, Sung-Soo Kim, Hyun-Dae Shin, Mi-Hyeon Jang, Min-Chul Shin, Geon-Ho Bahn, Eun-Kyung Paik, Jae-Hyung Park, Chang-Ju Ki. Protective effect of shenqi-wan against H2O2-induced apoptosis in hippocampal neuronal cells. The American journal of Chinese medicine. vol 31. issue 5. 2004-05-14. PMID:14696671. |
protective effect of shenqi-wan against h2o2-induced apoptosis in hippocampal neuronal cells. |
2004-05-14 |
2023-08-12 |
Not clear |
| Hyun-Taeg Shin, Seok-Hee Chung, Jong-Soo Lee, Sung-Soo Kim, Hyun-Dae Shin, Mi-Hyeon Jang, Min-Chul Shin, Geon-Ho Bahn, Eun-Kyung Paik, Jae-Hyung Park, Chang-Ju Ki. Protective effect of shenqi-wan against H2O2-induced apoptosis in hippocampal neuronal cells. The American journal of Chinese medicine. vol 31. issue 5. 2004-05-14. PMID:14696671. |
the present study investigated whether shenqi-wan possesses a protective effect against hydrogen peroxide (h2o2)-induced apoptosis of the hippocampal cell line hib5. |
2004-05-14 |
2023-08-12 |
Not clear |