| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anna Kolarova, Ralph Ringer, Martin G Täuber, Stephen L Lei. Blockade of NMDA receptor subtype NR2B prevents seizures but not apoptosis of dentate gyrus neurons in bacterial meningitis in infant rats. BMC neuroscience. vol 4. 2004-07-07. PMID:13129439. |
here we evaluated the effect of ro 25-6981 on hippocampal neuronal apoptosis in an infant rat model of meningitis due to streptococcus pneumoniae. |
2004-07-07 |
2023-08-12 |
rat |
| Marina Ioudina, Etsuro Uemura, Heather West Greenle. Glucose insufficiency alters neuronal viability and increases susceptibility to glutamate toxicity. Brain research. vol 1004. issue 1-2. 2004-06-24. PMID:15033434. |
we investigated the effect of a restricted supply of glucose on neuronal vulnerability to glutamate by assaying cellular atp levels (cellular energy production), 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (mtt) reduction (mitochondrial function), lactate dehydrogenase (ldh) release (cellular viability) and activation of caspase-3 (apoptosis) in rat hippocampal neurons cultured in media (1.7, 5 and 25 mm glucose) with or without 100 microm glutamate. |
2004-06-24 |
2023-08-12 |
rat |
| Katsunori Iwasaki, Kenichi Mishima, Nobuaki Egashira, Izzettin Hatip Al-Khatib, Daisuke Ishibashi, Keiichi Irie, Hirotoshi Kobayashi, Takashi Egawa, Michihiro Fujiwar. Effect of nilvadipine on the cerebral ischemia-induced impairment of spatial memory and hippocampal apoptosis in rats. Journal of pharmacological sciences. vol 93. issue 2. 2004-06-18. PMID:14578587. |
effect of nilvadipine on the cerebral ischemia-induced impairment of spatial memory and hippocampal apoptosis in rats. |
2004-06-18 |
2023-08-12 |
rat |
| Katsunori Iwasaki, Kenichi Mishima, Nobuaki Egashira, Izzettin Hatip Al-Khatib, Daisuke Ishibashi, Keiichi Irie, Hirotoshi Kobayashi, Takashi Egawa, Michihiro Fujiwar. Effect of nilvadipine on the cerebral ischemia-induced impairment of spatial memory and hippocampal apoptosis in rats. Journal of pharmacological sciences. vol 93. issue 2. 2004-06-18. PMID:14578587. |
on the other hand, repeated cerebral ischemia (10 min ischemia x 2, 1 h interval) impaired spatial memory and induced hippocampal apoptosis 7 days after the final occlusion/reperfusion. |
2004-06-18 |
2023-08-12 |
rat |
| Katsunori Iwasaki, Kenichi Mishima, Nobuaki Egashira, Izzettin Hatip Al-Khatib, Daisuke Ishibashi, Keiichi Irie, Hirotoshi Kobayashi, Takashi Egawa, Michihiro Fujiwar. Effect of nilvadipine on the cerebral ischemia-induced impairment of spatial memory and hippocampal apoptosis in rats. Journal of pharmacological sciences. vol 93. issue 2. 2004-06-18. PMID:14578587. |
however, mrna expression of the apoptosis-related early oncogene bax and cpp 32 (caspase-3) was observed after 24 h. in these rats, nilvadipine, but not amlodipine, significantly improved memory, concomitantly decreased hippocampal apoptosis, and suppressed both bax and cpp 32 expression. |
2004-06-18 |
2023-08-12 |
rat |
| Katsunori Iwasaki, Kenichi Mishima, Nobuaki Egashira, Izzettin Hatip Al-Khatib, Daisuke Ishibashi, Keiichi Irie, Hirotoshi Kobayashi, Takashi Egawa, Michihiro Fujiwar. Effect of nilvadipine on the cerebral ischemia-induced impairment of spatial memory and hippocampal apoptosis in rats. Journal of pharmacological sciences. vol 93. issue 2. 2004-06-18. PMID:14578587. |
these results suggest that nilvadipine improved the memory impairment in repeated ischemia by reducing bax and cpp 32 expression and suppressing the induction of apoptosis in the hippocampus. |
2004-06-18 |
2023-08-12 |
rat |
| Paolo G Marciano, Julia Brettschneider, Elisabetta Manduchi, Jason E Davis, Scott Eastman, Ramesh Raghupathi, Kathryn E Saatman, Terence P Speed, Christian J Stoeckert, James H Eberwine, Tracy K McIntos. Neuron-specific mRNA complexity responses during hippocampal apoptosis after traumatic brain injury. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 12. 2004-06-10. PMID:15044525. |
neuron-specific mrna complexity responses during hippocampal apoptosis after traumatic brain injury. |
2004-06-10 |
2023-08-12 |
mouse |
| Seiji Shioda, Hirokazu Ohtaki, Ryusuke Suzuki, Tomoya Nakamachi, Fumiko Takenoya, Kenji Dohi, Shigeo Nakaj. [Prevention of delayed neuronal cell death by PACAP and its molecular mechanism]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 123. issue 4. 2004-06-10. PMID:15056939. |
ischemic delayed neuronal cell death (apoptosis) in the hippocampus is prevented by pacap. |
2004-06-10 |
2023-08-12 |
mouse |
| Kan Liu, Andrew J Paterson, Fengxue Zhang, Joanne McAndrew, Ken-Ichiro Fukuchi, J Michael Wyss, Ling Peng, Yong Hu, Jeffrey E Kudlo. Accumulation of protein O-GlcNAc modification inhibits proteasomes in the brain and coincides with neuronal apoptosis in brain areas with high O-GlcNAc metabolism. Journal of neurochemistry. vol 89. issue 4. 2004-06-04. PMID:15140202. |
later, some hippocampal cells, but not purkinje cells, undergo apoptosis. |
2004-06-04 |
2023-08-12 |
Not clear |
| Li Yang, Kyoko Omori, Junko Suzukawa, Chiyoko Inagak. Calcineurin-mediated BAD Ser155 dephosphorylation in ammonia-induced apoptosis of cultured rat hippocampal neurons. Neuroscience letters. vol 357. issue 1. 2004-06-03. PMID:15036616. |
calcineurin-mediated bad ser155 dephosphorylation in ammonia-induced apoptosis of cultured rat hippocampal neurons. |
2004-06-03 |
2023-08-12 |
rat |
| Li Yang, Kyoko Omori, Junko Suzukawa, Chiyoko Inagak. Calcineurin-mediated BAD Ser155 dephosphorylation in ammonia-induced apoptosis of cultured rat hippocampal neurons. Neuroscience letters. vol 357. issue 1. 2004-06-03. PMID:15036616. |
we previously reported that ammonia induced apoptosis in cultured rat hippocampal neurons with moderate increases in the intracellular calcium concentration and decreases in phospho-bad levels. |
2004-06-03 |
2023-08-12 |
rat |
| Sarah M Richardson-Burns, Kenneth L Tyle. Regional differences in viral growth and central nervous system injury correlate with apoptosis. Journal of virology. vol 78. issue 10. 2004-05-27. PMID:15113925. |
vark-induced apoptosis was limited to the hippocampus in vivo, and in vitro both viruses induced apoptosis equally in mhc but vark induced significantly less apoptosis than t3d in mcc. |
2004-05-27 |
2023-08-12 |
mouse |
| Laura Korhonen, Ulla Näpänkangas, Håkan Steen, Yuming Chen, Rodrigo Martinez, Dan Lindhol. Differential regulation of X-chromosome-linked inhibitor of apoptosis protein (XIAP) and caspase-3 by NMDA in developing hippocampal neurons; involvement of the mitochondrial pathway in NMDA-mediated neuronal survival. Experimental cell research. vol 295. issue 2. 2004-05-20. PMID:15093730. |
differential regulation of x-chromosome-linked inhibitor of apoptosis protein (xiap) and caspase-3 by nmda in developing hippocampal neurons; involvement of the mitochondrial pathway in nmda-mediated neuronal survival. |
2004-05-20 |
2023-08-12 |
Not clear |
| Laura Korhonen, Ulla Näpänkangas, Håkan Steen, Yuming Chen, Rodrigo Martinez, Dan Lindhol. Differential regulation of X-chromosome-linked inhibitor of apoptosis protein (XIAP) and caspase-3 by NMDA in developing hippocampal neurons; involvement of the mitochondrial pathway in NMDA-mediated neuronal survival. Experimental cell research. vol 295. issue 2. 2004-05-20. PMID:15093730. |
here, we show that treatment with low concentrations of nmda upregulates the neuroprotective molecule, x-chromosome-linked inhibitor of apoptosis protein (xiap) in cultured hippocampal neurons at the post-transcriptional level. |
2004-05-20 |
2023-08-12 |
Not clear |
| Paul J Lucassen, Eberhard Fuchs, Boldizsár Czé. Antidepressant treatment with tianeptine reduces apoptosis in the hippocampal dentate gyrus and temporal cortex. Biological psychiatry. vol 55. issue 8. 2004-05-17. PMID:15050859. |
antidepressant treatment with tianeptine reduces apoptosis in the hippocampal dentate gyrus and temporal cortex. |
2004-05-17 |
2023-08-12 |
Not clear |
| Hyun-Taeg Shin, Seok-Hee Chung, Jong-Soo Lee, Sung-Soo Kim, Hyun-Dae Shin, Mi-Hyeon Jang, Min-Chul Shin, Geon-Ho Bahn, Eun-Kyung Paik, Jae-Hyung Park, Chang-Ju Ki. Protective effect of shenqi-wan against H2O2-induced apoptosis in hippocampal neuronal cells. The American journal of Chinese medicine. vol 31. issue 5. 2004-05-14. PMID:14696671. |
protective effect of shenqi-wan against h2o2-induced apoptosis in hippocampal neuronal cells. |
2004-05-14 |
2023-08-12 |
Not clear |
| Hyun-Taeg Shin, Seok-Hee Chung, Jong-Soo Lee, Sung-Soo Kim, Hyun-Dae Shin, Mi-Hyeon Jang, Min-Chul Shin, Geon-Ho Bahn, Eun-Kyung Paik, Jae-Hyung Park, Chang-Ju Ki. Protective effect of shenqi-wan against H2O2-induced apoptosis in hippocampal neuronal cells. The American journal of Chinese medicine. vol 31. issue 5. 2004-05-14. PMID:14696671. |
the present study investigated whether shenqi-wan possesses a protective effect against hydrogen peroxide (h2o2)-induced apoptosis of the hippocampal cell line hib5. |
2004-05-14 |
2023-08-12 |
Not clear |
| Hyun-Taeg Shin, Seok-Hee Chung, Jong-Soo Lee, Sung-Soo Kim, Hyun-Dae Shin, Mi-Hyeon Jang, Min-Chul Shin, Geon-Ho Bahn, Eun-Kyung Paik, Jae-Hyung Park, Chang-Ju Ki. Protective effect of shenqi-wan against H2O2-induced apoptosis in hippocampal neuronal cells. The American journal of Chinese medicine. vol 31. issue 5. 2004-05-14. PMID:14696671. |
these results suggest that shenqi-wan may exert its protective effect against h2o2-induced apoptosis via inhibition of nmda receptors in hippocampal neuronal cells. |
2004-05-14 |
2023-08-12 |
Not clear |
| Marina Ioudina, Etsuro Uemur. A three amino acid peptide, Gly-Pro-Arg, protects and rescues cell death induced by amyloid beta-peptide. Experimental neurology. vol 184. issue 2. 2004-04-02. PMID:14769384. |
our findings suggest that gpr can rescue cultured rat hippocampal neurons from abeta-induced neuronal death by inhibiting caspase-3/p53-dependent apoptosis. |
2004-04-02 |
2023-08-12 |
rat |
| H A Volk, K Burkhardt, H Potschka, J Chen, A Becker, W Lösche. Neuronal expression of the drug efflux transporter P-glycoprotein in the rat hippocampus after limbic seizures. Neuroscience. vol 123. issue 3. 2004-03-31. PMID:14706787. |
increased pgp expression in hippocampal neurons is likely to affect the action of drugs with intraneuronal targets and, in view of recent evidence from other cell types, could be associated with prevention of apoptosis which is involved in neuronal damage developing after seizures such as produced by pilocarpine. |
2004-03-31 |
2023-08-12 |
rat |