Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Tsuneo Takadera, Yoko Shiraishi, Takao Ohyashik. Prostaglandin E2 induced caspase-dependent apoptosis possibly through activation of EP2 receptors in cultured hippocampal neurons. Neurochemistry international. vol 45. issue 5. 2004-09-16. PMID:15234114. |
prostaglandin e2 increased the intracellular concentration of camp, and the selective ep2 agonist butaprost also induced apoptosis accompanied by increasing camp levels in hippocampal cells. |
2004-09-16 |
2023-08-12 |
Not clear |
Tsuneo Takadera, Yoko Shiraishi, Takao Ohyashik. Prostaglandin E2 induced caspase-dependent apoptosis possibly through activation of EP2 receptors in cultured hippocampal neurons. Neurochemistry international. vol 45. issue 5. 2004-09-16. PMID:15234114. |
moreover, a cell permeable camp analog, dibutyryl camp also induced apoptosis in hippocampal cells. |
2004-09-16 |
2023-08-12 |
Not clear |
Tsuneo Takadera, Yoko Shiraishi, Takao Ohyashik. Prostaglandin E2 induced caspase-dependent apoptosis possibly through activation of EP2 receptors in cultured hippocampal neurons. Neurochemistry international. vol 45. issue 5. 2004-09-16. PMID:15234114. |
we showed in this report that prostaglandin e2 directly induced apoptosis in hippocampal neurons. |
2004-09-16 |
2023-08-12 |
Not clear |
Toshimitsu Suzuki, Antonio V Delgado-Escueta, Kripamoy Aguan, Maria E Alonso, Jun Shi, Yuji Hara, Motohiro Nishida, Tomohiro Numata, Marco T Medina, Tamaki Takeuchi, Ryoji Morita, Dongsheng Bai, Subramaniam Ganesh, Yoshihisa Sugimoto, Johji Inazawa, Julia N Bailey, Adriana Ochoa, Aurelio Jara-Prado, Astrid Rasmussen, Jaime Ramos-Peek, Sergio Cordova, Francisco Rubio-Donnadieu, Yushi Inoue, Makiko Osawa, Sunao Kaneko, Hirokazu Oguni, Yasuo Mori, Kazuhiro Yamakaw. Mutations in EFHC1 cause juvenile myoclonic epilepsy. Nature genetics. vol 36. issue 8. 2004-09-13. PMID:15258581. |
overexpression of efhc1 in mouse hippocampal primary culture neurons induced apoptosis that was significantly lowered by the mutations. |
2004-09-13 |
2023-08-12 |
mouse |
b' Jun Chen, Weiguo Zhu, Qiusheng Chen, Ling L\\xc3\\xb. [Effects of lead on the Brn-3a expression and the apoptosis in hippocampus neurons]. Wei sheng yan jiu = Journal of hygiene research. vol 33. issue 2. 2004-08-24. PMID:15208987.' |
[effects of lead on the brn-3a expression and the apoptosis in hippocampus neurons]. |
2004-08-24 |
2023-08-12 |
Not clear |
Makoto Hamanoue, Akira Yoshioka, Toya Ohashi, Yoshikatsu Eto, Ken Takamats. NF-kappaB prevents TNF-alpha-induced apoptosis in an oligodendrocyte cell line. Neurochemical research. vol 29. issue 8. 2004-08-19. PMID:15260136. |
nuclear factor kappa beta (nf-kappab) inhibits apoptosis in sensory, hippocampal, and striatal neurons of the central nervous system. |
2004-08-19 |
2023-08-12 |
human |
Dongyan Yang, Chaoke Liang, Yinlong Jin, Dewen Wan. [Effect of arsenic toxicity on morphology and viability of enzyme in primary culture of rat hippocampal neurons]. Wei sheng yan jiu = Journal of hygiene research. vol 32. issue 4. 2004-08-13. PMID:14535089. |
the morphometric analysis showed that the isolated neonatal hippocampal neurons exposed to lower concentration of arsenic had cytoplasm vacuoles, frothing and nuclear condensation with the intact membrane, indicating the possible induction of apoptosis, whereas higher dose of arsenic leaded to the appearance of necrosis. |
2004-08-13 |
2023-08-12 |
rat |
Dongyan Yang, Chaoke Liang, Yinlong Jin, Dewen Wan. [Effect of arsenic toxicity on morphology and viability of enzyme in primary culture of rat hippocampal neurons]. Wei sheng yan jiu = Journal of hygiene research. vol 32. issue 4. 2004-08-13. PMID:14535089. |
it is suggested that the neonatal hippocampal neurons of rat treated with different doses of arsenic suffered from morphological changes including degeneration, apoptosis and necrosis in various degrees. |
2004-08-13 |
2023-08-12 |
rat |
Jennifer S Hoshooley, David F Sherr. Neuron production, neuron number, and structure size are seasonally stable in the hippocampus of the food-storing black-capped chickadee (Poecile atricapillus). Behavioral neuroscience. vol 118. issue 2. 2004-08-12. PMID:15113260. |
two weeks later, birds were killed by overdose, and hippocampal neuron production, apoptosis, neuron number, and hippocampal volume were determined. |
2004-08-12 |
2023-08-12 |
Not clear |
Jennifer S Hoshooley, David F Sherr. Neuron production, neuron number, and structure size are seasonally stable in the hippocampus of the food-storing black-capped chickadee (Poecile atricapillus). Behavioral neuroscience. vol 118. issue 2. 2004-08-12. PMID:15113260. |
chickadees collected in october, november, january, february, and march did not differ in neuron production, apoptosis, hippocampal volume, or neuron number. |
2004-08-12 |
2023-08-12 |
Not clear |
Alejandra R Alvarez, Juan A Godoy, Karin Mullendorff, Gonzalo H Olivares, Miguel Bronfman, Nibaldo C Inestros. Wnt-3a overcomes beta-amyloid toxicity in rat hippocampal neurons. Experimental cell research. vol 297. issue 1. 2004-08-12. PMID:15194435. |
we further demonstrate that wnt-3a protects hippocampal neurons from apoptosis induced by abeta. |
2004-08-12 |
2023-08-12 |
rat |
A N Kalehua, J E Nagel, L M Whelchel, J J Gides, R S Pyle, R J Smith, J W Kusiak, D D Tau. Monocyte chemoattractant protein-1 and macrophage inflammatory protein-2 are involved in both excitotoxin-induced neurodegeneration and regeneration. Experimental cell research. vol 297. issue 1. 2004-08-12. PMID:15194436. |
furthermore, this chemokine apoptotic effect could also be observed in vivo as intrahippocampal injections of mcp-1 or mip-2 resulted in the apoptosis of hippocampal neurons, thus supporting a direct role of these chemokines in neuronal death. |
2004-08-12 |
2023-08-12 |
Not clear |
Charles Thompson, Devin Gary, Mark Mattson, Alex Mackenzie, George S Robertso. Kainic acid-induced naip expression in the hippocampus is blocked in mice lacking TNF receptors. Brain research. Molecular brain research. vol 123. issue 1-2. 2004-08-03. PMID:15046874. |
we report here that systemic administration of kainic acid rapidly elevates expression of mrna encoding neuronal apoptosis inhibitor protein (naip) in the hippocampus and that this increase does not occur in mice that lack tnf receptors. |
2004-08-03 |
2023-08-12 |
mouse |
Colin P J Glover, Darren J Heywood, Alison S Bienemann, Ulrich Deuschle, James N C Kew, James B Une. Adenoviral expression of CREB protects neurons from apoptotic and excitotoxic stress. Neuroreport. vol 15. issue 7. 2004-07-27. PMID:15129168. |
the over-expression of creb but not a-creb was found to protect primary hippocampal neurons from staurosporine-induced apoptosis, glutamate induced excitotoxicity and exposure to an in vitro ischaemic stress. |
2004-07-27 |
2023-08-12 |
Not clear |
Ying Liu, Hongwei Ren, Caihong Wu, Shuhua Bai, Xiaokun Zhang, Binggen R. Attenuation of zinc-induced neuronal death by the interaction of growth inhibitory factor with Rab3A in rat hippocampal neurons. Neuroscience letters. vol 358. issue 3. 2004-07-16. PMID:15039103. |
in an in vitro cell culture system, 300 microm zn(2+) readily induced death of hippocampal neuronal cells, which was characterized by massive necrosis and a minor degree of apoptosis. |
2004-07-16 |
2023-08-12 |
rat |
YueMei Zhang, XiaoFeng Lu, Bhagu R Bhavnan. Equine estrogens differentially inhibit DNA fragmentation induced by glutamate in neuronal cells by modulation of regulatory proteins involved in programmed cell death. BMC neuroscience. vol 4. 2004-07-15. PMID:14693041. |
recent data indicate that excitotoxicity of high levels of neurotransmitter glutamate may be mediated via programmed cell death (apoptosis) and that it can be prevented in ht22 mouse hippocampal cells by various equine estrogens with delta8,17beta-estradiol (delta8,17beta-e2) being the most potent. |
2004-07-15 |
2023-08-12 |
mouse |
Ling-Qun Zhu, Ji-ping Fan, Qi-fu Huang, Su-lun Sun, Ying Gao, Yi-huai Zou, Zhuang Zhang, Li-yun He, Hong Zhen. [Study on the anti-apopotosis induced by hypoxia/hypoglycemia and reoxygenation of panax notoginseng saponins in cultured rat hippocampal neurons]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 28. issue 1. 2004-07-15. PMID:15015268. |
to study the inhibitory effects of panax notoginseng saponins(pns) on apoptosis induced by hypoxia/hypoglycemia and reoxygenation in cultured rat hippocampal neurons. |
2004-07-15 |
2023-08-12 |
rat |
Vivi M Heine, Suharti Maslam, Marian Joëls, Paul J Lucasse. Prominent decline of newborn cell proliferation, differentiation, and apoptosis in the aging dentate gyrus, in absence of an age-related hypothalamus-pituitary-adrenal axis activation. Neurobiology of aging. vol 25. issue 3. 2004-07-15. PMID:15123342. |
neurogenesis and apoptosis in the hippocampal dentate gyrus (dg) occur during development and adulthood. |
2004-07-15 |
2023-08-12 |
rat |
Zhen-Guo Li, Weixian Zhang, Anders A F Sim. C-peptide enhances insulin-mediated cell growth and protection against high glucose-induced apoptosis in SH-SY5Y cells. Diabetes/metabolism research and reviews. vol 19. issue 5. 2004-07-13. PMID:12951645. |
we have previously reported that c-peptide exerts preventive and therapeutic effects on diabetic neuropathy in type 1 diabetic bb/wor-rats and that it prevents duration-dependent hippocampal apoptosis in the same animal model. |
2004-07-13 |
2023-08-12 |
human |
Sthephen L Leib, Chris Heimgartner, Yoeng-Delphine Bifrare, Jutta M Loeffler, Martin G Täaube. Dexamethasone aggravates hippocampal apoptosis and learning deficiency in pneumococcal meningitis in infant rats. Pediatric research. vol 54. issue 3. 2004-07-09. PMID:12788989. |
dexamethasone aggravates hippocampal apoptosis and learning deficiency in pneumococcal meningitis in infant rats. |
2004-07-09 |
2023-08-12 |
rat |