| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Del Signore, S Mandillo, A Rizzo, E Di Mauro, A Mele, R Negri, A Oliverio, P Pagg. Hippocampal gene expression is modulated by hypergravity. The European journal of neuroscience. vol 19. issue 3. 2004-03-29. PMID:14984417. |
the modulated genes code for proteins involved in a wide range of cellular functions (dna/rna metabolism, protein processing, intermediate metabolism, cytoskeleton and motility, cell cycle and apoptosis, signal transduction, neuronal structure/function), suggesting that rotation + hypergravity may affect several aspects of the hippocampal function in order to compensate for environmental changes. |
2004-03-29 |
2023-08-12 |
mouse |
| Marieke C Wichers, Michael Mae. The role of indoleamine 2,3-dioxygenase (IDO) in the pathophysiology of interferon-alpha-induced depression. Journal of psychiatry & neuroscience : JPN. vol 29. issue 1. 2004-03-25. PMID:14719046. |
3-oh-kyn is able to produce oxidative stress by increasing the production of reactive oxygen species (ros), and quin may produce overstimulation of hippocampal n-methyl-d-aspartate (nmda) receptors, which leads to apoptosis and hippocampal atrophy. |
2004-03-25 |
2023-08-12 |
Not clear |
| Laura Solforosi, Jose R Criado, Dorian B McGavern, Sebastian Wirz, Manuel Sánchez-Alavez, Shuei Sugama, Lorraine A DeGiorgio, Bruce T Volpe, Erika Wiseman, Gil Abalos, Eliezer Masliah, Donald Gilden, Michael B Oldstone, Bruno Conti, R Anthony Williamso. Cross-linking cellular prion protein triggers neuronal apoptosis in vivo. Science (New York, N.Y.). vol 303. issue 5663. 2004-03-25. PMID:14752167. |
here, cross-linking prpc in vivo with specific monoclonal antibodies was found to trigger rapid and extensive apoptosis in hippocampal and cerebellar neurons. |
2004-03-25 |
2023-08-12 |
Not clear |
| Charles L Limoli, Erich Giedzinski, Radoslaw Rola, Shinji Otsuka, Theo D Palmer, John R Fik. Radiation response of neural precursor cells: linking cellular sensitivity to cell cycle checkpoints, apoptosis and oxidative stress. Radiation research. vol 161. issue 1. 2004-03-12. PMID:14680400. |
in an effort to understand the mechanisms underlying radiation-induced stem cell dysfunction, neural precursor cells isolated from the adult rat hippocampus were analyzed for acute (0-24 h) and chronic (3-33 days) changes in apoptosis and reactive oxygen species (ros) after exposure to x rays. |
2004-03-12 |
2023-08-12 |
mouse |
| Corneliu N Craciunescu, Elliott C Brown, Mei-Heng Mar, Craig D Albright, Marie R Nadeau, Steven H Zeise. Folic acid deficiency during late gestation decreases progenitor cell proliferation and increases apoptosis in fetal mouse brain. The Journal of nutrition. vol 134. issue 1. 2004-02-20. PMID:14704311. |
in mice and rats, maternal dietary choline intake during late pregnancy modulates mitosis and apoptosis in progenitor cells of the fetal hippocampus and septum. |
2004-02-20 |
2023-08-12 |
mouse |
| A Goldbart, B W Row, L Kheirandish, A Schurr, E Gozal, S Z Guo, R S Payne, Z Cheng, K R Brittian, D Goza. Intermittent hypoxic exposure during light phase induces changes in cAMP response element binding protein activity in the rat CA1 hippocampal region: water maze performance correlates. Neuroscience. vol 122. issue 3. 2004-02-17. PMID:14622901. |
creb phosphorylation and dna binding, as well as the presence of apoptosis in the ca1 region of the hippocampus were examined in sprague-dawley male rats exposed to ih. |
2004-02-17 |
2023-08-12 |
rat |
| Takehiko Iijima, Tatsuya Mishima, Kimio Akagawa, Yasuhide Iwa. Mitochondrial hyperpolarization after transient oxygen-glucose deprivation and subsequent apoptosis in cultured rat hippocampal neurons. Brain research. vol 993. issue 1-2. 2004-02-12. PMID:14642839. |
mitochondrial hyperpolarization after transient oxygen-glucose deprivation and subsequent apoptosis in cultured rat hippocampal neurons. |
2004-02-12 |
2023-08-12 |
rat |
| Aileen M Lynch, Michelle Moore, Sarah Craig, Peter E Lonergan, Darren S Martin, Marina A Lync. Analysis of interleukin-1 beta-induced cell signaling activation in rat hippocampus following exposure to gamma irradiation. Protective effect of eicosapentaenoic acid. The Journal of biological chemistry. vol 278. issue 51. 2004-01-30. PMID:14525971. |
the trigger that leads to jnk activation has not been identified, although, in rat hippocampus at least, irradiation-induced apoptosis has been coupled with increased accumulation of reactive oxygen species (ros). |
2004-01-30 |
2023-08-12 |
rat |
| Bernardo Moreno-López, Carmen Romero-Grimaldi, José Angel Noval, Maribel Murillo-Carretero, Esperanza R Matarredona, Carmen Estrad. Nitric oxide is a physiological inhibitor of neurogenesis in the adult mouse subventricular zone and olfactory bulb. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 1. 2004-01-30. PMID:14715941. |
systemic administration of the nos inhibitors n(omega)-nitro-l-arginine methyl ester or 7-nitroindazole to adult mice produced a dose- and time-dependent increase in the number of mitotic cells in the subventricular zone, rostral migratory stream, and olfactory bulb, but not in the dentate gyrus of the hippocampus, without affecting apoptosis. |
2004-01-30 |
2023-08-12 |
mouse |
| Shu-Yan Li, Ju-Hua Ni, De-Sheng Xu, Hong-Ti Ji. Down-regulation of GluR2 is associated with Ca2+-dependent protease activities in kainate-induced apoptotic cell death in cultured [correction of culturd] rat hippocampal neurons. Neuroscience letters. vol 352. issue 2. 2004-01-23. PMID:14625034. |
these results suggest that long-term exposure of hippocampal neurons to kainate causes apoptosis, whose mechanisms involve multiple ca(2+)-dependent cascades, in which ampa receptor subunits may be targets for ca(2+)-activated protease-mediated degradation during kainate-induced neuron apoptosis. |
2004-01-23 |
2023-08-12 |
rat |
| Ying-Chao Chang, A-Min Huang, Yu-Min Kuo, Shan-Tair Wang, Yung-Yee Chang, Chao-Ching Huan. Febrile seizures impair memory and cAMP response-element binding protein activation. Annals of neurology. vol 54. issue 6. 2004-01-14. PMID:14681880. |
neither hippocampal neuronal damage nor apoptosis was noted within 72 hours after fs, nor was there significant hippocampal neuronal loss, aberrant mossy fiber sprouting, or altered seizure threshold to pentylenetetrazol in any fs group at adulthood. |
2004-01-14 |
2023-08-12 |
rat |
| Lisa M Melton, Alexander B Keith, Sue Davis, Arthur E Oakley, James A Edwardson, Christopher M Morri. Chronic glial activation, neurodegeneration, and APP immunoreactive deposits following acute administration of double-stranded RNA. Glia. vol 44. issue 1. 2003-12-15. PMID:12951652. |
in close temporal succession to glial activation, there is neurodegeneration, with neuron loss involving apoptosis in selected brain regions including the septal nucleus, hippocampus, cortex and thalamus, along with hippocampal atrophy. |
2003-12-15 |
2023-08-12 |
human |
| J Lu, D Goula, N Sousa, O F X Almeid. Ionotropic and metabotropic glutamate receptor mediation of glucocorticoid-induced apoptosis in hippocampal cells and the neuroprotective role of synaptic N-methyl-D-aspartate receptors. Neuroscience. vol 121. issue 1. 2003-12-05. PMID:12946705. |
ionotropic and metabotropic glutamate receptor mediation of glucocorticoid-induced apoptosis in hippocampal cells and the neuroprotective role of synaptic n-methyl-d-aspartate receptors. |
2003-12-05 |
2023-08-12 |
rat |
| L E Haynes, C L Lendon, D J Barber, I J Mitchel. 17 Beta-oestradiol attenuates dexamethasone-induced lethal and sublethal neuronal damage in the striatum and hippocampus. Neuroscience. vol 120. issue 3. 2003-12-04. PMID:12895519. |
this association may result from the toxic actions of endogenous corticosteroids which can induce apoptosis of hippocampal neurons. |
2003-12-04 |
2023-08-12 |
rat |
| L E Haynes, C L Lendon, D J Barber, I J Mitchel. 17 Beta-oestradiol attenuates dexamethasone-induced lethal and sublethal neuronal damage in the striatum and hippocampus. Neuroscience. vol 120. issue 3. 2003-12-04. PMID:12895519. |
injections of dexamethasone (when preceded by vehicle injections) resulted in elevated levels of apoptosis and sub-lethal damage, as demonstrated by reduced levels of microtubule-associated protein-2-immunopositive neurons, in the striatum and hippocampus. |
2003-12-04 |
2023-08-12 |
rat |
| Joanna Sekita-Krzak, Krystyna Czerny, Iwona Zebrowska-Łupina, Maria Stepniewska, Józef Visconti, Jacek Kozie. Neuroprotective effect of ACTH (4-9) in degeneration of hippocampal nerve cells caused by dexamethasone: morphological studies. Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina. vol 57. issue 2. 2003-12-03. PMID:12898847. |
this chemical inhibits dexamethasone induced degeneration of hippocampal nerve cells having morphological features characteristic of apoptosis. |
2003-12-03 |
2023-08-12 |
mouse |
| Koichi Uemura, Sumihisa Hoshino, Koji Uchida, Ryosuke Tsuruta, Tsuyoshi Maekawa, Ken-ichi Yoshid. Hypothermia attenuates delayed cortical cell death and ROS generation following CO inhalation. Toxicology letters. vol 145. issue 2. 2003-12-02. PMID:14581162. |
we demonstrated there were both apoptosis and necrosis in the cortex, basal ganglia and hippocampus in a case of human co accident. |
2003-12-02 |
2023-08-12 |
human |
| Mark A Lovell, Chengsong Xie, Shuling Xiong, William R Markesber. Wilms' tumor suppressor (WT1) is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer's disease. Brain research. vol 983. issue 1-2. 2003-11-28. PMID:12914969. |
laser confocal microscopy of hippocampal neuron cultures undergoing apoptosis induced by amyloid beta peptide (abeta) or staurosporine demonstrated significant time-dependent elevations of wt1 correlating with increased levels of apoptosis. |
2003-11-28 |
2023-08-12 |
Not clear |
| Honghui Chen, Shenggang Sun, Yuanwu Mei, Changqin Liu, Anqiu Liu, Etang Ton. The effect of beta-amyloid on neurons and the influence of glucocorticoid and age on such effect. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 22. issue 3. 2003-11-26. PMID:12658818. |
to explore the relationship between beta-amyloid (a beta) and the pathogenesis of alzheimer disease (ad), after injection of beta-amyloid into the rat brain, the apoptosis of nerve cells and acetylcholine (ach) content in rat hippocampus were examined by employing tunel technique and base hydroxylamine colorimetry respectively. |
2003-11-26 |
2023-08-12 |
rat |
| Honghui Chen, Shenggang Sun, Yuanwu Mei, Changqin Liu, Anqiu Liu, Etang Ton. The effect of beta-amyloid on neurons and the influence of glucocorticoid and age on such effect. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 22. issue 3. 2003-11-26. PMID:12658818. |
a beta peptide could strongly induce the apoptosis of neurons in hippocampus, cortex and striate body (p < 0.05 or p < 0.01). |
2003-11-26 |
2023-08-12 |
rat |