| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Katsunori Iwasaki, Izzettin Hatip-Al-Khatib, Nobuaki Egashira, Yuki Akiyoshi, Takashi Arai, Kenichi Mishima, Yuki Takagaki, Keiichiro Inui, Michihiro Fujiwar. Ovariectomy combined with amyloid beta(1-42) impairs memory by decreasing acetylcholine release and alpha 7nAChR expression without induction of apoptosis in the hippocampus CA1 neurons of rats. Neurotoxicity research. vol 6. issue 4. 2005-04-22. PMID:15545013. |
in this study, the effect of ovariectomy and amyloid beta(1-42) (abeta(1-42))on eight-armed radial maze performance, acetylcholine (ach) release, alpha7nach receptor (alpha7nachr), glyceraldehyde 3-phosphate dehydrogenase (gapdh) expression, and apoptosis of ca1 neurons in the dorsal hippocampus were investigated in rat. |
2005-04-22 |
2023-08-12 |
rat |
| Katsunori Iwasaki, Izzettin Hatip-Al-Khatib, Nobuaki Egashira, Yuki Akiyoshi, Takashi Arai, Kenichi Mishima, Yuki Takagaki, Keiichiro Inui, Michihiro Fujiwar. Ovariectomy combined with amyloid beta(1-42) impairs memory by decreasing acetylcholine release and alpha 7nAChR expression without induction of apoptosis in the hippocampus CA1 neurons of rats. Neurotoxicity research. vol 6. issue 4. 2005-04-22. PMID:15545013. |
this effect was accompanied by a decrease of the basal ach level (67%), a7nachr mrna expression (52%) and a7nachr/gapdh ratio (44%) without induction of apoptosis in the dorsal hippocampus. |
2005-04-22 |
2023-08-12 |
rat |
| Katsunori Iwasaki, Izzettin Hatip-Al-Khatib, Nobuaki Egashira, Yuki Akiyoshi, Takashi Arai, Kenichi Mishima, Yuki Takagaki, Keiichiro Inui, Michihiro Fujiwar. Ovariectomy combined with amyloid beta(1-42) impairs memory by decreasing acetylcholine release and alpha 7nAChR expression without induction of apoptosis in the hippocampus CA1 neurons of rats. Neurotoxicity research. vol 6. issue 4. 2005-04-22. PMID:15545013. |
these results suggest that ovariectomy-induced hormonal deprivation after 4 weeks, when accompanied by abeta(1-42) accumulation in the dorsal hippocampus, could impair memory by decreasing ach release and a7nachr expression without inducing apoptosis in the ca1 field of the dorsal hippocampus. |
2005-04-22 |
2023-08-12 |
rat |
| Jie Zhang, Xue-Fei Wang, Zhong-Bing Lu, Nian-Qing Liu, Bao-Lu Zha. The effects of meso-2,3-dimercaptosuccinic acid and oligomeric procyanidins on acute lead neurotoxicity in rat hippocampus. Free radical biology & medicine. vol 37. issue 7. 2005-04-21. PMID:15336320. |
it was proved that reactive oxygen species and oxidative damage were implicated in the induction of apoptosis induced by lead in the hippocampus. |
2005-04-21 |
2023-08-12 |
rat |
| Takeshi Tanaka, Yukio Horikawa, Takanori Kawamoto, Noriko Kabe-Sakurai, Jun Takeda, Masahiko Mikun. Expression profile of mRNAs from rat hippocampus and its application to microarray. Brain research. Molecular brain research. vol 129. issue 1-2. 2005-04-19. PMID:15469879. |
severe stress has been shown to induce neuronal atrophy and apoptosis, especially in the hippocampus, which is thought to be a region of the brain important in stress-related disorders. |
2005-04-19 |
2023-08-12 |
rat |
| Kurt Watson, Guo-Huang Fa. Macrophage inflammatory protein 2 inhibits beta-amyloid peptide (1-42)-mediated hippocampal neuronal apoptosis through activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase signaling pathways. Molecular pharmacology. vol 67. issue 3. 2005-04-12. PMID:15608143. |
macrophage inflammatory protein 2 inhibits beta-amyloid peptide (1-42)-mediated hippocampal neuronal apoptosis through activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase signaling pathways. |
2005-04-12 |
2023-08-12 |
Not clear |
| Zhiguo Chen, Rui-Sheng Duan, Hernan Concha Quezada, Eilhard Mix, Inger Nennesmo, Abdu Adem, Bengt Winblad, Jie Zh. Increased microglial activation and astrogliosis after intranasal administration of kainic acid in C57BL/6 mice. Journal of neurobiology. vol 62. issue 2. 2005-04-11. PMID:15459893. |
by using nissl's staining, neurodegeneration was found in area ca3 of hippocampus, and neuronal apoptosis was demonstrated by enhanced fas(cd95/apo-1) expression detected by immunohistochemistry and western blotting. |
2005-04-11 |
2023-08-12 |
mouse |
| Thor D Stein, Nicholas J Anders, Charles DeCarli, Sic L Chan, Mark P Mattson, Jeffrey A Johnso. Neutralization of transthyretin reverses the neuroprotective effects of secreted amyloid precursor protein (APP) in APPSW mice resulting in tau phosphorylation and loss of hippocampal neurons: support for the amyloid hypothesis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 35. 2005-04-05. PMID:15342738. |
chronic infusion of an antibody against transthyretin into the hippocampus of mice overexpressing app with the swedish mutation (app(sw)) leads to increased abeta, tau phosphorylation, and neuronal loss and apoptosis within the ca1 neuronal field. |
2005-04-05 |
2023-08-12 |
mouse |
| M Mori, D L Burgess, L A Gefrides, P J Foreman, J T Opferman, S J Korsmeyer, E A Cavalheiro, Md G Naffah-Mazzacoratti, J L Noebel. Expression of apoptosis inhibitor protein Mcl1 linked to neuroprotection in CNS neurons. Cell death and differentiation. vol 11. issue 11. 2005-03-02. PMID:15286683. |
in resistant c57bl/6j mice, mcl1 protein levels remain persistently elevated in hippocampal pyramidal neurons after seizures, but fall rapidly in c3h/hej hippocampus, coinciding with extensive neuronal apoptosis. |
2005-03-02 |
2023-08-12 |
mouse |
| M D Siegelin, L S Kossatz, J Winckler, A Ram. Regulation of XIAP and Smac/DIABLO in the rat hippocampus following transient forebrain ischemia. Neurochemistry international. vol 46. issue 1. 2005-02-22. PMID:15567514. |
we investigated the expression of xiap (x chromosome-linked inhibitor of apoptosis protein) and smac/diablo, a newly identified mitochondrial apoptogenig molecule in the hippocampus following transient global ischemia. |
2005-02-22 |
2023-08-12 |
rat |
| Yun Li, Changman Zhou, John W Calvert, Austin R T Colohan, John H Zhan. Multiple effects of hyperbaric oxygen on the expression of HIF-1 alpha and apoptotic genes in a global ischemia-hypotension rat model. Experimental neurology. vol 191. issue 1. 2005-02-18. PMID:15589527. |
these molecular changes were accompanied by massive cell loss in the hippocampal regions and to a lesser degree in the cortex, with features of apoptosis. |
2005-02-18 |
2023-08-12 |
rat |
| Jean-Luc Daval, Paul Ver. Apoptosis and neurogenesis after transient hypoxia in the developing rat brain. Seminars in perinatology. vol 28. issue 4. 2005-02-15. PMID:15565785. |
in vivo, hypoxia induced cell damage in the ca1 subfield of the hippocampus, where the total number of cells was reduced by 27% at days 6-7 postreoxygenation, with histopathological hallmarks of apoptosis. |
2005-02-15 |
2023-08-12 |
rat |
| Georg Johannes Müller, Christine Stadelmann, Lone Bastholm, Folmer Elling, Hans Lassmann, Flemming Fryd Johanse. Ischemia leads to apoptosis--and necrosis-like neuron death in the ischemic rat hippocampus. Brain pathology (Zurich, Switzerland). vol 14. issue 4. 2005-02-14. PMID:15605989. |
ischemia leads to apoptosis--and necrosis-like neuron death in the ischemic rat hippocampus. |
2005-02-14 |
2023-08-12 |
rat |
| Wei Wang, Mark Solc, Ping Ji, Kimberly E Do. Corticotropin-releasing hormone potentiates neural injury induced by oxygen-glucose deprivation: a possible involvement of microglia. Neuroscience letters. vol 371. issue 2-3. 2005-01-25. PMID:15519743. |
in the present study, we have determined the effect of crh on oxygen-glucose deprivation (ogd) induced apoptosis in fetal hippocampal neurons. |
2005-01-25 |
2023-08-12 |
Not clear |
| Eberhard Fuchs, Boldizsár Czéh, Maarten H P Kole, Thomas Michaelis, Paul J Lucasse. Alterations of neuroplasticity in depression: the hippocampus and beyond. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 14 Suppl 5. 2005-01-19. PMID:15550346. |
even though long-lasting social conflict does not lead to a loss of principal cells, the hippocampal changes were accompanied by modifications in the incidence of apoptosis. |
2005-01-19 |
2023-08-12 |
Not clear |
| Philippe Fossati, Andrei Radtchenko, Patrice Boye. Neuroplasticity: from MRI to depressive symptoms. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 14 Suppl 5. 2005-01-19. PMID:15550349. |
may be responsible for increased apoptosis in the hippocampus and prefrontal cortex corresponding to the cognitive impairment described in depression. |
2005-01-19 |
2023-08-12 |
Not clear |
| J Guan, G B Thomas, H Lin, S Mathai, D C Bachelor, S George, P D Gluckma. Neuroprotective effects of the N-terminal tripeptide of insulin-like growth factor-1, glycine-proline-glutamate (GPE) following intravenous infusion in hypoxic-ischemic adult rats. Neuropharmacology. vol 47. issue 6. 2005-01-13. PMID:15527823. |
gpe reduced both caspase-3-dependent and -independent apoptosis in the hippocampus. |
2005-01-13 |
2023-08-12 |
rat |
| Rommy von Bernhardi, Jaime Eugení. Microglial reactivity to beta-amyloid is modulated by astrocytes and proinflammatory factors. Brain research. vol 1025. issue 1-2. 2005-01-06. PMID:15464759. |
conditioned media obtained from microglial cultures exposed to abeta induced apoptosis of hippocampal cells. |
2005-01-06 |
2023-08-12 |
Not clear |
| Lauren Mitchell, S Hope Smith, Johann S Braun, Karl-Heinz Herzog, Joerg R Weber, Elaine I Tuomane. Dual phases of apoptosis in pneumococcal meningitis. The Journal of infectious diseases. vol 190. issue 11. 2004-12-30. PMID:15529270. |
significant injury during bacterial meningitis arises from mechanisms of neuronal apoptosis, particularly in the hippocampus. |
2004-12-30 |
2023-08-12 |
mouse |
| Amanda J Patel, Michel Lazdunsk. The 2P-domain K+ channels: role in apoptosis and tumorigenesis. Pflugers Archiv : European journal of physiology. vol 448. issue 3. 2004-12-22. PMID:15133669. |
moreover, genetic transfer of task subunits into hippocampal neurons that lack task-3, induces apoptosis. |
2004-12-22 |
2023-08-12 |
Not clear |