| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nazan Uysal, Kazim Tugyan, Berkant Muammer Kayatekin, Osman Acikgoz, Husnu Alper Bagriyanik, Sevil Gonenc, Durgul Ozdemir, Ilkay Aksu, Ayca Topcu, Ilgi Semi. The effects of regular aerobic exercise in adolescent period on hippocampal neuron density, apoptosis and spatial memory. Neuroscience letters. vol 383. issue 3. 2005-08-09. PMID:15878799. |
the present study examined the effects of regular aerobic exercise on spatial memory using the morris water maze, cell density and apoptosis of hippocampus in adolescent rats. |
2005-08-09 |
2023-08-12 |
rat |
| Nazan Uysal, Kazim Tugyan, Berkant Muammer Kayatekin, Osman Acikgoz, Husnu Alper Bagriyanik, Sevil Gonenc, Durgul Ozdemir, Ilkay Aksu, Ayca Topcu, Ilgi Semi. The effects of regular aerobic exercise in adolescent period on hippocampal neuron density, apoptosis and spatial memory. Neuroscience letters. vol 383. issue 3. 2005-08-09. PMID:15878799. |
this result may derive from treadmill exercise-induced increase cell density without altering of apoptosis in the hippocampus and dentate gyrus of adolescent rats. |
2005-08-09 |
2023-08-12 |
rat |
| Yong Cheol Ji, Young Baeg Kim, Seung Won Park, Sung Nam Hwang, Byung Kook Min, Hyun Jong Hong, Jeong Taik Kwon, Jong Sik Su. Neuroprotective effect of ginseng total saponins in experimental traumatic brain injury. Journal of Korean medical science. vol 20. issue 2. 2005-07-14. PMID:15832003. |
contusion volume and the number of hippocampal neurons were calculated with apoptosis evaluated by tunel staining. |
2005-07-14 |
2023-08-12 |
rat |
| Gigliola Ramírez, Rodrigo Toro, Heinz Döbeli, Rommy von Bernhard. Protection of rat primary hippocampal cultures from A beta cytotoxicity by pro-inflammatory molecules is mediated by astrocytes. Neurobiology of disease. vol 19. issue 1-2. 2005-07-12. PMID:15837580. |
2 microm a beta(1-42) induced apoptosis of hippocampal cells and lps + ifn-gamma reduced the apoptosis induced by a beta. |
2005-07-12 |
2023-08-12 |
rat |
| Gigliola Ramírez, Rodrigo Toro, Heinz Döbeli, Rommy von Bernhard. Protection of rat primary hippocampal cultures from A beta cytotoxicity by pro-inflammatory molecules is mediated by astrocytes. Neurobiology of disease. vol 19. issue 1-2. 2005-07-12. PMID:15837580. |
however, lps + ifn-gamma prevented apoptosis only in hippocampal cultures containing astrocytes. |
2005-07-12 |
2023-08-12 |
rat |
| Woong Sun, Adam Winseck, Sharon Vinsant, Ok-hee Park, Hyun Kim, Ronald W Oppenhei. Programmed cell death of adult-generated hippocampal neurons is mediated by the proapoptotic gene Bax. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 49. 2005-07-07. PMID:15590937. |
several markers for apoptosis failed to reveal cell death in bax-deficient mice, and this, together with a progressive increase in neuron number in the dg of the bax knock-out, indicates that bax is critical for the pcd of adult-generated hippocampal neurons. |
2005-07-07 |
2023-08-12 |
mouse |
| Anders A F Sima, Zhen-guo L. The effect of C-peptide on cognitive dysfunction and hippocampal apoptosis in type 1 diabetic rats. Diabetes. vol 54. issue 5. 2005-07-05. PMID:15855338. |
the effect of c-peptide on cognitive dysfunction and hippocampal apoptosis in type 1 diabetic rats. |
2005-07-05 |
2023-08-12 |
rat |
| Anders A F Sima, Zhen-guo L. The effect of C-peptide on cognitive dysfunction and hippocampal apoptosis in type 1 diabetic rats. Diabetes. vol 54. issue 5. 2005-07-05. PMID:15855338. |
the results show that several partially interrelated apoptotic mechanisms are involved in primary encephalopathy and suggest that impaired insulinomimetic action by c-peptide plays a prominent role in cognitive dysfunction and hippocampal apoptosis in type 1 diabetes. |
2005-07-05 |
2023-08-12 |
rat |
| Ewa Nagańska, Ewa Matyj. Expression of apoptosis-related proteins in model of anoxia in vitro. Folia neuropathologica. vol 43. issue 1. 2005-06-30. PMID:15827887. |
we examined the expression of proteins related to programmed cell death in hippocampal neurons in vitro, exposed to pure anoxia or pretreated with apoptosis modulating agents: zinc and zinc chelator - tpen. |
2005-06-30 |
2023-08-12 |
Not clear |
| Ewa Nagańska, Ewa Matyj. Expression of apoptosis-related proteins in model of anoxia in vitro. Folia neuropathologica. vol 43. issue 1. 2005-06-30. PMID:15827887. |
this strong immunoreactivity of proapototic proteins (p53 and bax) in hippocampal cultures exposed to anoxia or/and tpen correlated with previous ultrastructural evidences of anoxia- and tpen-induced apoptosis, while the overexpression of anti-apoptotic protein (bcl-2 and bcl-x) in zinc-pretreated cultures evidenced the protective ability of this metal against apoptosis in model of anoxia in vitro. |
2005-06-30 |
2023-08-12 |
Not clear |
| Irene Knuesel, Abigail Elliott, Hong-Jung Chen, Isabelle M Mansuy, Mary B Kenned. A role for synGAP in regulating neuronal apoptosis. The European journal of neuroscience. vol 21. issue 3. 2005-06-28. PMID:15733080. |
in all mutants, however, an abnormally high number of neurons in the hippocampus and cortex undergo apoptosis, as detected by caspase-3 activation. |
2005-06-28 |
2023-08-12 |
mouse |
| S Thees, G B Hubbard, J Winckler, C Schultz, A Ram. Specific alteration of the Bax/Bcl2 ratio and cytochrome c without execution of apoptosis in the hippocampus of aged baboons. Restorative neurology and neuroscience. vol 23. issue 1. 2005-06-28. PMID:15846027. |
specific alteration of the bax/bcl2 ratio and cytochrome c without execution of apoptosis in the hippocampus of aged baboons. |
2005-06-28 |
2023-08-12 |
Not clear |
| S Thees, G B Hubbard, J Winckler, C Schultz, A Ram. Specific alteration of the Bax/Bcl2 ratio and cytochrome c without execution of apoptosis in the hippocampus of aged baboons. Restorative neurology and neuroscience. vol 23. issue 1. 2005-06-28. PMID:15846027. |
the aim of this study was to investigate the potential occurrence of apoptosis in the hippocampus of aged baboons. |
2005-06-28 |
2023-08-12 |
Not clear |
| Zhong Xu, Ru-xiang Xu, Bao-song Liu, Xiao-dan Jiang, Tao Huang, Lian-shu Ding, Jun Yua. Time window characteristics of cultured rat hippocampal neurons subjected to ischemia and reperfusion. Chinese journal of traumatology = Zhonghua chuang shang za zhi. vol 8. issue 3. 2005-06-28. PMID:15896277. |
to explore cell death and apoptosis in rat hippocampal neurons at different time points after ischemia, hypoxia and reperfusion injury and to elucidate time window characteristics in ischemia neuronal injury. |
2005-06-28 |
2023-08-12 |
rat |
| Manel G Medina, Maria Dolores Ledesma, Jorge E Domínguez, Miguel Medina, Delia Zafra, Francesc Alameda, Carlos G Dotti, Pilar Navarr. Tissue plasminogen activator mediates amyloid-induced neurotoxicity via Erk1/2 activation. The EMBO journal. vol 24. issue 9. 2005-06-24. PMID:15861134. |
here we show in primary hippocampal neurons that tpa promotes a catalytic-independent activation of the extracellular regulated kinase (erk)1/2 signal transduction pathway through the n-methyl-d-aspartate receptor, g-proteins and protein kinase c. this results in gsk3 activation in a process that requires de novo synthesis of proteins, and leads to tau aberrant phosphorylation, microtubule destabilization and apoptosis. |
2005-06-24 |
2023-08-12 |
mouse |
| Dalinda Liazoghli, Sebastien Perreault, Kristina D Micheva, Mylène Desjardins, Nicole Lecler. Fragmentation of the Golgi apparatus induced by the overexpression of wild-type and mutant human tau forms in neurons. The American journal of pathology. vol 166. issue 5. 2005-06-21. PMID:15855649. |
in both primary hippocampal neurons and jnpl3 mice, the tau-induced ga fragmentation was not caused by apoptosis. |
2005-06-21 |
2023-08-12 |
mouse |
| S M Strukova, E V Kiseleva, T N Dugina, E Glusa, T P Storozhevykh, V G Pineli. [Effect of thrombin on survival of hippocampal neurons]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 91. issue 1. 2005-06-16. PMID:15773580. |
thrombin (10 nm) was shown to inhibit 100-mkm glutamate--or 10-mkm hemoglobin-induced apoptosis of the rat hippocampal neurons. |
2005-06-16 |
2023-08-12 |
rat |
| Zhen-Guo Li, Weixian Zhang, Anders A F Sim. The role of impaired insulin/IGF action in primary diabetic encephalopathy. Brain research. vol 1037. issue 1-2. 2005-06-16. PMID:15777748. |
we have previously shown that hippocampal neuronal apoptosis accompanied by impaired cognitive functions occurs in type 1 diabetic bb/wor rats. |
2005-06-16 |
2023-08-12 |
rat |
| Laura Korhonen, Inga Hansson, Jyrki P Kukkonen, Karin Brännvall, Masaaki Kobayashi, Ken Takamatsu, Dan Lindhol. Hippocalcin protects against caspase-12-induced and age-dependent neuronal degeneration. Molecular and cellular neurosciences. vol 28. issue 1. 2005-05-19. PMID:15607944. |
neuronal apoptosis inhibitor protein (naip), known to interact with hippocalcin, was not altered, but hippocampal neurons from gene-deleted mice were more sensitive to excitotoxicity caused by kainic acid. |
2005-05-19 |
2023-08-12 |
mouse |
| A A Shute, R J Cormier, K L Moulder, A Benz, K E Isenberg, C F Zorumski, S Menneric. Astrocytes exert a pro-apoptotic effect on neurons in postnatal hippocampal cultures. Neuroscience. vol 131. issue 2. 2005-05-03. PMID:15708478. |
we investigated conditions that promote basal and activity-dependent neuronal apoptosis in postnatal rat hippocampal cultures. |
2005-05-03 |
2023-08-12 |
rat |