| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Q Niu, Y Yang, Q Zhang, P Niu, S He, M Di Gioacchino, P Conti, P Boscol. The relationship between Bcl-gene expression and learning and memory impairment in chronic aluminum-exposed rats. Neurotoxicity research. vol 12. issue 3. 2008-02-29. PMID:17967740. |
neuronal apoptosis was extensive in the brain of al-exposed groups, and the expressions of bcl-2 protein in frontal cortex, cerebellum and hippocampus of al-exposed rats was stronger. |
2008-02-29 |
2023-08-12 |
rat |
| Myeung Ju Kim, Hyoung-Soo Lim, Young Bok Yoo, Young Il Lee, Dae-Hyun Hahm, Hye-Jung Lee, Kee Wook Jung, Jong-Wan Kim, Sung Moon Yoe, David Chanwook Chung, Young Pyo Chan. Expression of CD95 and CD95L on astrocytes in the CA1 area of the immature rat hippocampus after hypoxia-ischemia injury. Comparative medicine. vol 57. issue 6. 2008-02-29. PMID:18246871. |
our findings show that increases in the expression of cd95 and cd95l after hi injury may involve astrocytic apoptosis in the 7-d-old rat hippocampus, and these molecules may act as targets or inducers of cell death. |
2008-02-29 |
2023-08-12 |
rat |
| Anders A F Sima, Hideki Kamiy. Is C-peptide replacement the missing link for successful treatment of neurological complications in type 1 diabetes? Current drug targets. vol 9. issue 1. 2008-02-28. PMID:18220711. |
c-peptide replacement partially prevents hippocampal neuronal apoptosis and cognitive deficits. |
2008-02-28 |
2023-08-12 |
Not clear |
| Siegfried Kasper, Bruce S McEwe. Neurobiological and clinical effects of the antidepressant tianeptine. CNS drugs. vol 22. issue 1. 2008-02-25. PMID:18072812. |
in particular, in the hippocampus, it prevents stress-induced dendritic atrophy, improves neurogenesis, reduces apoptosis and normalizes metabolite levels and hippocampal volume. |
2008-02-25 |
2023-08-12 |
Not clear |
| Karen Fuenzalida, Rodrigo Quintanilla, Patricio Ramos, Daniela Piderit, Rodrigo A Fuentealba, Gabriela Martinez, Nibaldo C Inestrosa, Miguel Bronfma. Peroxisome proliferator-activated receptor gamma up-regulates the Bcl-2 anti-apoptotic protein in neurons and induces mitochondrial stabilization and protection against oxidative stress and apoptosis. The Journal of biological chemistry. vol 282. issue 51. 2008-02-20. PMID:17965419. |
here we show that the ppargamma agonist rosiglitazone (rgz) protects hippocampal and dorsal root ganglion neurons against abeta-induced mitochondrial damage and ngf deprivation-induced apoptosis, respectively, and promotes pc12 cell survival. |
2008-02-20 |
2023-08-12 |
Not clear |
| Shirley L Chao, Jason M Moss, G Jean Harr. Lead-induced alterations of apoptosis and neurotrophic factor mRNA in the developing rat cortex, hippocampus, and cerebellum. Journal of biochemical and molecular toxicology. vol 21. issue 5. 2008-02-19. PMID:17912701. |
lead-induced alterations of apoptosis and neurotrophic factor mrna in the developing rat cortex, hippocampus, and cerebellum. |
2008-02-19 |
2023-08-12 |
rat |
| Tobias Engel, Brona M Murphy, Clara K Schindler, David C Henshal. Elevated p53 and lower MDM2 expression in hippocampus from patients with intractable temporal lobe epilepsy. Epilepsy research. vol 77. issue 2-3. 2008-02-14. PMID:17942278. |
recent studies of resected hippocampus from patients with intractable temporal lobe epilepsy (tle) have yielded biochemical evidence of signalling pathways associated with apoptosis. |
2008-02-14 |
2023-08-12 |
human |
| Zhihong Guo, Haiyang Jiang, Xiangru Xu, Wenzhen Duan, Mark P Mattso. Leptin-mediated cell survival signaling in hippocampal neurons mediated by JAK STAT3 and mitochondrial stabilization. The Journal of biological chemistry. vol 283. issue 3. 2008-02-14. PMID:17993459. |
by enhancing mitochondrial resistance to apoptosis and excitotoxicity, our findings suggest that leptin signaling serves a neurotrophic function in the developing and adult hippocampus. |
2008-02-14 |
2023-08-12 |
mouse |
| Ping Liu, Ju-ying Wang, Qian Li, Fu-yu Xu, Zi-ying Wang, Hong-yan Xu, Zhao-ping Liu, Xiu-mei Zhan. [Effect of baicalin on HSP70 expression of hippocampal neurons in focal brain ischemia-reperfusion injury rats]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 41. issue 7. 2008-02-11. PMID:17007353. |
to investigate the effect of baicalin on the hippocampal neuronal apoptosis and the expression of hsp70 in rats with focal brain ischemia-reperfusion injury. |
2008-02-11 |
2023-08-12 |
rat |
| Xiaohong Xu, Xiaoxiang Zhen. Potential involvement of calcium and nitric oxide in protective effects of puerarin on oxygen-glucose deprivation in cultured hippocampal neurons. Journal of ethnopharmacology. vol 113. issue 3. 2008-01-31. PMID:17698307. |
flow cytometric analysis of annexin-v and propidium iodide (pi) labeling cells found that apoptosis and necrosis were significantly reduced in the cultured hippocampal neurons by addition of pur during 3h ogd and for the following 24h. |
2008-01-31 |
2023-08-12 |
rat |
| Caroline L Bellac, Roney S Coimbra, Franziska Simon, Hans Imboden, Stephen L Lei. Gene and protein expression of galectin-3 and galectin-9 in experimental pneumococcal meningitis. Neurobiology of disease. vol 28. issue 2. 2008-01-11. PMID:17706429. |
cortical necrosis and hippocampal apoptosis in pneumococcal meningitis (pm). |
2008-01-11 |
2023-08-12 |
Not clear |
| M S Petrik, J M B Wilson, S C Grant, S J Blackband, R C Tabata, X Shan, C Krieger, C A Sha. Magnetic resonance microscopy and immunohistochemistry of the CNS of the mutant SOD murine model of ALS reveals widespread neural deficits. Neuromolecular medicine. vol 9. issue 3. 2007-12-27. PMID:17914180. |
increased apoptosis, gfap positive astrocytes, and/or activated microglia were observed in all those cns regions that showed volume loss except for the hippocampus. |
2007-12-27 |
2023-08-12 |
mouse |
| Ying Jin, Ying Fan, En-zhi Yan, Zhuo Liu, Zhi-hong Zong, Zhi-min Q. Effects of sodium ferulate on amyloid-beta-induced MKK3/MKK6-p38 MAPK-Hsp27 signal pathway and apoptosis in rat hippocampus. Acta pharmacologica Sinica. vol 27. issue 10. 2007-12-11. PMID:17007737. |
effects of sodium ferulate on amyloid-beta-induced mkk3/mkk6-p38 mapk-hsp27 signal pathway and apoptosis in rat hippocampus. |
2007-12-11 |
2023-08-12 |
rat |
| Robert F Hevne. The cerebral cortex malformation in thanatophoric dysplasia: neuropathology and pathogenesis. Acta neuropathologica. vol 110. issue 3. 2007-12-07. PMID:16133544. |
defective patterning accounts for hippocampal dysplasia, while increased proliferation and decreased apoptosis account for temporal lobe hyperplasia and premature development of aberrant sulci. |
2007-12-07 |
2023-08-12 |
mouse |
| Armen A Galoyan, Josef Krieglstein, Susanne Klumpp, Kristina E Danielian, Karine A Galoian, Wolfram Kremers, Kristina B Bezirganyan, Tigran K Davtya. Effect of hypothalamic proline-rich peptide (PRP-1) on neuronal and bone marrow cell apoptosis. Neurochemical research. vol 32. issue 11. 2007-12-06. PMID:17549627. |
here we investigated the influence of prp-1 on staurosporine-induced apoptosis of postnatal hippocampal cells and on doxorubicin-induced bone marrow granulocyte- and monocyte apoptosis. |
2007-12-06 |
2023-08-12 |
cattle |
| Armen A Galoyan, Josef Krieglstein, Susanne Klumpp, Kristina E Danielian, Karine A Galoian, Wolfram Kremers, Kristina B Bezirganyan, Tigran K Davtya. Effect of hypothalamic proline-rich peptide (PRP-1) on neuronal and bone marrow cell apoptosis. Neurochemical research. vol 32. issue 11. 2007-12-06. PMID:17549627. |
we demonstrate that prp-1 significantly reduced apoptosis of postnatal hippocampal cells induced by staurosporine. |
2007-12-06 |
2023-08-12 |
cattle |
| Armen A Galoyan, Josef Krieglstein, Susanne Klumpp, Kristina E Danielian, Karine A Galoian, Wolfram Kremers, Kristina B Bezirganyan, Tigran K Davtya. Effect of hypothalamic proline-rich peptide (PRP-1) on neuronal and bone marrow cell apoptosis. Neurochemical research. vol 32. issue 11. 2007-12-06. PMID:17549627. |
previously obtained data and results of the current studies suggested that the hypothalamic prp-1 possibly represents an endogenous peptide whose primary functions are to regulate myelopoiesis and neuron survival as we provide evidence that prp can differentially reduce both staurosporine- and doxorubicin-induced hippocampal and bone marrow cell apoptosis. |
2007-12-06 |
2023-08-12 |
cattle |
| Shuqiao Yao, Min Peng, Xiongzhao Zhu, Ming Cheng, Xiaoli Q. Heat shock protein72 protects hippocampal neurons from apoptosis induced by chronic psychological stress. The International journal of neuroscience. vol 117. issue 11. 2007-12-06. PMID:17917925. |
heat shock protein72 protects hippocampal neurons from apoptosis induced by chronic psychological stress. |
2007-12-06 |
2023-08-12 |
mouse |
| Shuqiao Yao, Min Peng, Xiongzhao Zhu, Ming Cheng, Xiaoli Q. Heat shock protein72 protects hippocampal neurons from apoptosis induced by chronic psychological stress. The International journal of neuroscience. vol 117. issue 11. 2007-12-06. PMID:17917925. |
chronic psychological stress is a kind of stress that could cause hippocampal neuron apoptosis. |
2007-12-06 |
2023-08-12 |
mouse |
| Shuqiao Yao, Min Peng, Xiongzhao Zhu, Ming Cheng, Xiaoli Q. Heat shock protein72 protects hippocampal neurons from apoptosis induced by chronic psychological stress. The International journal of neuroscience. vol 117. issue 11. 2007-12-06. PMID:17917925. |
to investigate the possible protective role of hsp72 in decreasing chronic psychological stress-induced hippocampal neuron apoptosis, this study analyzed hsp72 expression, apoptotic neurons in the hippocampus of mice. |
2007-12-06 |
2023-08-12 |
mouse |