| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Katherine E Galvin, Hong Ye, Derek J Erstad, Rod Feddersen, Cynthia Wetmor. Gli1 induces G2/M arrest and apoptosis in hippocampal but not tumor-derived neural stem cells. Stem cells (Dayton, Ohio). vol 26. issue 4. 2008-08-15. PMID:18276799. |
gli1 induces g2/m arrest and apoptosis in hippocampal but not tumor-derived neural stem cells. |
2008-08-15 |
2023-08-12 |
Not clear |
| In Koo Hwang, Ki-Yeon Yoo, Hua Li, Jung Hoon Choi, Choong Hyun Lee, Dae Won Chung, In Se Lee, Dae Won Kim, Soo Young Choi, Moo-Ho Wo. Time course of changes in immunoreactivities of GABA degradation enzymes in the hippocampal CA1 region after adrenalectomy in gerbils. Neurochemical research. vol 33. issue 5. 2008-08-11. PMID:18030617. |
adrenalectomy (adx) has been useful for a good in vivo model for apoptosis in the hippocampus by the absence of corticosteroids following adx. |
2008-08-11 |
2023-08-12 |
Not clear |
| J M Barker, L A M Gale. Repeated estradiol administration alters different aspects of neurogenesis and cell death in the hippocampus of female, but not male, rats. Neuroscience. vol 152. issue 4. 2008-08-07. PMID:18353559. |
we therefore demonstrate a clear sex difference in the response to estradiol of hippocampal neurogenesis and apoptosis in adult rats, with adult females being more responsive to the effects of estradiol than males. |
2008-08-07 |
2023-08-12 |
rat |
| Anders A F Sima, Weixian Zhang, Zhen-guo Li, Hideki Kamiy. The effects of C-peptide on type 1 diabetic polyneuropathies and encephalopathy in the BB/Wor-rat. Experimental diabetes research. vol 2008. 2008-08-06. PMID:18437223. |
c-peptide prevents hippocampal apoptosis and cognitive deficits. |
2008-08-06 |
2023-08-12 |
Not clear |
| Dinesh K Thotala, Dennis E Hallahan, Eugenia M Yazlovitskay. Inhibition of glycogen synthase kinase 3 beta attenuates neurocognitive dysfunction resulting from cranial irradiation. Cancer research. vol 68. issue 14. 2008-08-06. PMID:18632640. |
here we show that glycogen synthase kinase 3beta (gsk-3beta) is required for radiation-induced hippocampal neuronal apoptosis and subsequent neurocognitive decline. |
2008-08-06 |
2023-08-12 |
mouse |
| Dinesh K Thotala, Dennis E Hallahan, Eugenia M Yazlovitskay. Inhibition of glycogen synthase kinase 3 beta attenuates neurocognitive dysfunction resulting from cranial irradiation. Cancer research. vol 68. issue 14. 2008-08-06. PMID:18632640. |
inhibition of gsk-3beta either by small molecules (sb216763 or sb415286) or by ectopic expression of kinase-inactive gsk-3beta before irradiation significantly attenuated radiation-induced apoptosis in hippocampal neurons. |
2008-08-06 |
2023-08-12 |
mouse |
| Dinesh K Thotala, Dennis E Hallahan, Eugenia M Yazlovitskay. Inhibition of glycogen synthase kinase 3 beta attenuates neurocognitive dysfunction resulting from cranial irradiation. Cancer research. vol 68. issue 14. 2008-08-06. PMID:18632640. |
gsk-3beta inhibition with sb216763 or sb415286 also decreased apoptosis in the subgranular zone of the hippocampus in irradiated mice, leading to improved cognitive function in irradiated animals. |
2008-08-06 |
2023-08-12 |
mouse |
| Dinesh K Thotala, Dennis E Hallahan, Eugenia M Yazlovitskay. Inhibition of glycogen synthase kinase 3 beta attenuates neurocognitive dysfunction resulting from cranial irradiation. Cancer research. vol 68. issue 14. 2008-08-06. PMID:18632640. |
studies of the molecular mechanisms of the cytoprotective effect showed that gsk-3beta activity in hippocampal neurons was not significantly altered by radiation, pointing to the indirect involvement of this enzyme in radiation-induced apoptosis. |
2008-08-06 |
2023-08-12 |
mouse |
| Solomon Raju Bhupanapadu Sunkesula, Umakanta Swain, Phanithi Prakash Bab. Cell death is associated with reduced base excision repair during chronic alcohol administration in adult rat brain. Neurochemical research. vol 33. issue 6. 2008-07-24. PMID:18259862. |
results of the current study revealed that frontal cortex exhibits a higher level of ethanol-induced apoptosis relative to hippocampus. |
2008-07-24 |
2023-08-12 |
rat |
| R Silva, A R Mesquita, J Bessa, J C Sousa, I Sotiropoulos, P Leão, O F X Almeida, N Sous. Lithium blocks stress-induced changes in depressive-like behavior and hippocampal cell fate: the role of glycogen-synthase-kinase-3beta. Neuroscience. vol 152. issue 3. 2008-07-21. PMID:18291594. |
although the mechanisms implicated in the genesis of mood disorders are still unclear, stress is known to predispose to depression, and recently, studies have related hippocampal neurogenesis and apoptosis to depression. |
2008-07-21 |
2023-08-12 |
rat |
| Sunil K Hota, Kalpana Barhwal, Shashi B Singh, G Ilavazhaga. Chronic hypobaric hypoxia induced apoptosis in CA1 region of hippocampus: a possible role of NMDAR mediated p75NTR upregulation. Experimental neurology. vol 212. issue 1. 2008-07-17. PMID:18466900. |
chronic hypobaric hypoxia induced apoptosis in ca1 region of hippocampus: a possible role of nmdar mediated p75ntr upregulation. |
2008-07-17 |
2023-08-12 |
rat |
| Sunil K Hota, Kalpana Barhwal, Shashi B Singh, G Ilavazhaga. Chronic hypobaric hypoxia induced apoptosis in CA1 region of hippocampus: a possible role of NMDAR mediated p75NTR upregulation. Experimental neurology. vol 212. issue 1. 2008-07-17. PMID:18466900. |
to study the contribution of apoptosis to hypobaric hypoxia induced cell death in the hippocampus, rat brains were examined for the occurrence of apoptosis by determining the number of cells showing dna breaks using terminal deoxynucleotidyl transferase-mediated utp nick end labeling (tunel) assay and chromatin condensation using hoechst staining along with estimation of caspase activity and expression of active caspase 3. |
2008-07-17 |
2023-08-12 |
rat |
| Sunil K Hota, Kalpana Barhwal, Shashi B Singh, G Ilavazhaga. Chronic hypobaric hypoxia induced apoptosis in CA1 region of hippocampus: a possible role of NMDAR mediated p75NTR upregulation. Experimental neurology. vol 212. issue 1. 2008-07-17. PMID:18466900. |
further, reduced expression of p75(ntr) expression by antisense nucleotide administration significantly decreased apoptosis in the ca1 region of hippocampus. |
2008-07-17 |
2023-08-12 |
rat |
| Sandra Guidi, Paola Bonasoni, Claudio Ceccarelli, Donatella Santini, Fabio Gualtieri, Elisabetta Ciani, Renata Bartesagh. Neurogenesis impairment and increased cell death reduce total neuron number in the hippocampal region of fetuses with Down syndrome. Brain pathology (Zurich, Switzerland). vol 18. issue 2. 2008-07-10. PMID:18093248. |
results show reduced neuron number in the ds hippocampal region and suggest that this defect is caused by disruption of neurogenesis and apoptosis, two fundamental processes underlying brain building. |
2008-07-10 |
2023-08-12 |
Not clear |
| Anne-Lie Svensson, Nora Bucht, Mathias Hallberg, Fred Nyber. Reversal of opiate-induced apoptosis by human recombinant growth hormone in murine foetus primary hippocampal neuronal cell cultures. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 20. 2008-06-24. PMID:18474854. |
reversal of opiate-induced apoptosis by human recombinant growth hormone in murine foetus primary hippocampal neuronal cell cultures. |
2008-06-24 |
2023-08-12 |
mouse |
| Anne-Lie Svensson, Nora Bucht, Mathias Hallberg, Fred Nyber. Reversal of opiate-induced apoptosis by human recombinant growth hormone in murine foetus primary hippocampal neuronal cell cultures. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 20. 2008-06-24. PMID:18474854. |
in this work, we demonstrate that gh may reverse opiate-induced apoptosis in cells derived from prenatal mouse hippocampus. |
2008-06-24 |
2023-08-12 |
mouse |
| Maoquan Li, Yanyan Wang, Yanwen Zhang, Zhou Zhou, Zhengping Y. Elevation of plasma corticosterone levels and hippocampal glucocorticoid receptor translocation in rats: a potential mechanism for cognition impairment following chronic low-power-density microwave exposure. Journal of radiation research. vol 49. issue 2. 2008-06-10. PMID:18198477. |
mw exposure increased levels of plasma corticosterone, and consequently gc receptor (gr) nuclear translocation and apoptosis in the hippocampus. |
2008-06-10 |
2023-08-12 |
rat |
| Yukitoshi Takahashi, Yuko Kubota, Etsuko Yamasaki, Kazumi Matsud. [Rasmussen encephalitis and non-herpetic acute limbic encephalitis]. Rinsho shinkeigaku = Clinical neurology. vol 48. issue 3. 2008-05-30. PMID:18409535. |
however, anti-double-stranded dna antibodies in patients with sle are reported to cross-react with n-terminal of glurepsilon2, and cause neuronal apoptosis in rat hippocampus, ensuing memory impairment, and emotional behavior impairment in mice. |
2008-05-30 |
2023-08-12 |
mouse |
| I V Kudriashova, M V Onufriev, I E Kudriashov, N V Guliaev. [Caspase-3 activity in the rat hippocampal slices reflects changes in synaptic plasticity]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 94. issue 1. 2008-05-20. PMID:18383726. |
our data suggest that high caspase-3 activity in hippocampal slices is involved in maintenance of synaptic plasticity but not necessarily related to apoptosis. |
2008-05-20 |
2023-08-12 |
rat |
| Ming-Wai Hung, George L Tipoe, Angela Ming-See Poon, Russel J Reiter, Man-Lung Fun. Protective effect of melatonin against hippocampal injury of rats with intermittent hypoxia. Journal of pineal research. vol 44. issue 2. 2008-05-05. PMID:18289174. |
also, melatonin treatment significantly reduced hippocampal mda levels and totally prevented apoptosis. |
2008-05-05 |
2023-08-12 |
rat |