| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ping He, Weihong He, Aiguo Wang, Tao Xia, Bayi Xu, Ming Zhang, Xuemin Che. PBDE-47-induced oxidative stress, DNA damage and apoptosis in primary cultured rat hippocampal neurons. Neurotoxicology. vol 29. issue 1. 2008-05-02. PMID:18054389. |
pbde-47-induced oxidative stress, dna damage and apoptosis in primary cultured rat hippocampal neurons. |
2008-05-02 |
2023-08-12 |
rat |
| Ping He, Weihong He, Aiguo Wang, Tao Xia, Bayi Xu, Ming Zhang, Xuemin Che. PBDE-47-induced oxidative stress, DNA damage and apoptosis in primary cultured rat hippocampal neurons. Neurotoxicology. vol 29. issue 1. 2008-05-02. PMID:18054389. |
this paper investigates the mechanism by studying the effects of oxidative stress, dna damage, and apoptosis induced by pbde-47 in cultured primary rat hippocampal neurons at different pbde-47-concentrations (0, 2.06, 20.6, and 41.2 microm). |
2008-05-02 |
2023-08-12 |
rat |
| Ping He, Weihong He, Aiguo Wang, Tao Xia, Bayi Xu, Ming Zhang, Xuemin Che. PBDE-47-induced oxidative stress, DNA damage and apoptosis in primary cultured rat hippocampal neurons. Neurotoxicology. vol 29. issue 1. 2008-05-02. PMID:18054389. |
these results suggested that pbde-47 could induce oxidative stress, dna damage, and apoptosis in primary rat hippocampal neurons. |
2008-05-02 |
2023-08-12 |
rat |
| Denis Grandgirard, Oliver Steiner, Martin G Täuber, Stephen L Lei. An infant mouse model of brain damage in pneumococcal meningitis. Acta neuropathologica. vol 114. issue 6. 2008-04-25. PMID:17938941. |
the histomorphological correlate of these sequelae is a pattern of brain damage characterized by necrotic tissue damage in the cerebral cortex and apoptosis of neurons in the hippocampal dentate gyrus. |
2008-04-25 |
2023-08-12 |
mouse |
| Denis Grandgirard, Oliver Steiner, Martin G Täuber, Stephen L Lei. An infant mouse model of brain damage in pneumococcal meningitis. Acta neuropathologica. vol 114. issue 6. 2008-04-25. PMID:17938941. |
histological evaluations of brain sections revealed apoptosis in the dentate gyrus of the hippocampus in 27% of infected c57bl/6 and in 5% of infected cd1 mice. |
2008-04-25 |
2023-08-12 |
mouse |
| Johann Sellner, Ralph Ringer, Pierre Baumann, Michèl Jonzier Perey, Bernhard Schmitt, Stephen L Lei. Effect of the NMDA-receptor antagonist dextromethorphan in infant rat pneumococcal meningitis. Current drug metabolism. vol 9. issue 1. 2008-04-24. PMID:18220575. |
we conclude that in this infant rat model of pneumococcal meningitis interference of the eea and nmda pathway using dm causes ataxia, attenuates epileptic seizures and increases hippocampal apoptosis, but is not effective in protecting the brain from injury. |
2008-04-24 |
2023-08-12 |
rat |
| X W Huang, H M Yin, C Ji, Y F Qin, R W Yang, Z Y Zha. Effects of perinatal hypothyroidism on rat behavior and its relation with apoptosis of hippocampus neurons. Journal of endocrinological investigation. vol 31. issue 1. 2008-04-16. PMID:18296899. |
effects of perinatal hypothyroidism on rat behavior and its relation with apoptosis of hippocampus neurons. |
2008-04-16 |
2023-08-12 |
rat |
| X W Huang, H M Yin, C Ji, Y F Qin, R W Yang, Z Y Zha. Effects of perinatal hypothyroidism on rat behavior and its relation with apoptosis of hippocampus neurons. Journal of endocrinological investigation. vol 31. issue 1. 2008-04-16. PMID:18296899. |
our study aimed to investigate the effects of perinatal hypothyroidism on behavior changes of rat pups and its relation with the apoptosis of hippocampus neurons. |
2008-04-16 |
2023-08-12 |
rat |
| X W Huang, H M Yin, C Ji, Y F Qin, R W Yang, Z Y Zha. Effects of perinatal hypothyroidism on rat behavior and its relation with apoptosis of hippocampus neurons. Journal of endocrinological investigation. vol 31. issue 1. 2008-04-16. PMID:18296899. |
tunel staining was used to analyze the apoptosis of neurons on ca3 region of hippocampus. |
2008-04-16 |
2023-08-12 |
rat |
| Quan-zhong Chang, De-hui Hu, Ming Chen, Ying Wang, Tian-ming Ga. [Neuroprotection of chloride channel blockers against NMDA-induced apoptosis of cultured rat hippocampal neurons]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 26. issue 2. 2008-04-14. PMID:16503518. |
[neuroprotection of chloride channel blockers against nmda-induced apoptosis of cultured rat hippocampal neurons]. |
2008-04-14 |
2023-08-12 |
rat |
| Katrine Fabricius, Gitta Wörtwein, Bente Pakkenber. The impact of maternal separation on adult mouse behaviour and on the total neuron number in the mouse hippocampus. Brain structure & function. vol 212. issue 5. 2008-04-03. PMID:18200448. |
apparently a single maternal separation can impact the number of neurons in mouse hippocampus either by a decrease of neurogenesis or as an increase in neuron apoptosis. |
2008-04-03 |
2023-08-12 |
mouse |
| Simone Molz, Helena Decker, Tharine Dal-Cim, Carla Cremonez, Fabiano M Cordova, Rodrigo B Leal, Carla I Tasc. Glutamate-induced toxicity in hippocampal slices involves apoptotic features and p38 MAPK signaling. Neurochemical research. vol 33. issue 1. 2008-04-01. PMID:17616814. |
however, glutamate-induced apoptosis and the signaling pathways related to glutamate-induced cell death in acute hippocampal slices remain elusive. |
2008-04-01 |
2023-08-12 |
Not clear |
| Simone Molz, Helena Decker, Tharine Dal-Cim, Carla Cremonez, Fabiano M Cordova, Rodrigo B Leal, Carla I Tasc. Glutamate-induced toxicity in hippocampal slices involves apoptotic features and p38 MAPK signaling. Neurochemical research. vol 33. issue 1. 2008-04-01. PMID:17616814. |
in the present study we have shown that glutamate induces apoptosis in hippocampal slices and it causes an impairment of cell viability that was dependent of ionotropic and metabotropic receptors activation and, may involve the activation of p38 mapk pathway. |
2008-04-01 |
2023-08-12 |
Not clear |
| Jung-Mi Han, Byung-Joon Chang, Tian-Zhu Li, Nong-Hoon Choe, Fu-Shi Quan, Bong-Jun Jang, Ik-Hyun Cho, Hea-Nam Hong, Jong-Hwan Le. Protective effects of ascorbic acid against lead-induced apoptotic neurodegeneration in the developing rat hippocampus in vivo. Brain research. vol 1185. 2008-03-28. PMID:17959157. |
at the end of the treatment, neuronal damage, apoptosis and blood lead levels were determined and the levels of bax and bcl-2 were immunodetected in the hippocampus of 21-day-old male pups. |
2008-03-28 |
2023-08-12 |
rat |
| Jung-Mi Han, Byung-Joon Chang, Tian-Zhu Li, Nong-Hoon Choe, Fu-Shi Quan, Bong-Jun Jang, Ik-Hyun Cho, Hea-Nam Hong, Jong-Hwan Le. Protective effects of ascorbic acid against lead-induced apoptotic neurodegeneration in the developing rat hippocampus in vivo. Brain research. vol 1185. 2008-03-28. PMID:17959157. |
histopathological evaluation demonstrated that ascorbic acid significantly attenuates apoptosis in the developing hippocampus and also spares hippocampal ca1, ca3 and dentate gyrus (dg) neurons. |
2008-03-28 |
2023-08-12 |
rat |
| Yi-Rong Wang, Ren-Yi Liu, Liang-Chun Wang, Hai-Feng Mao, Jia-Qin Che. Effect of Huwentoxin-I on the Fas and TNF apoptosis pathway in the hippocampus of rat with global cerebral ischemia. Toxicon : official journal of the International Society on Toxinology. vol 50. issue 8. 2008-03-25. PMID:17900647. |
effect of huwentoxin-i on the fas and tnf apoptosis pathway in the hippocampus of rat with global cerebral ischemia. |
2008-03-25 |
2023-08-12 |
rat |
| Yi-Rong Wang, Ren-Yi Liu, Liang-Chun Wang, Hai-Feng Mao, Jia-Qin Che. Effect of Huwentoxin-I on the Fas and TNF apoptosis pathway in the hippocampus of rat with global cerebral ischemia. Toxicon : official journal of the International Society on Toxinology. vol 50. issue 8. 2008-03-25. PMID:17900647. |
it also reduced the expression level of related factors of fas and tumor necrosis factor death receptor apoptosis pathways in the hippocampus. |
2008-03-25 |
2023-08-12 |
rat |
| Yujuan Li, Ge Liang, Shouping Wang, Qingcheng Meng, Qiujun Wang, Huafeng We. Effects of fetal exposure to isoflurane on postnatal memory and learning in rats. Neuropharmacology. vol 53. issue 8. 2008-03-21. PMID:17959201. |
apoptosis was quantified in the hippocampus and cortex at 2 and 18h after exposure in the fetal brain and in the postnatal day 5 (p5) pup brain. |
2008-03-21 |
2023-08-12 |
rat |
| Brent L Williams, Mady Hornig, Kavitha Yaddanapudi, W Ian Lipki. Hippocampal poly(ADP-Ribose) polymerase 1 and caspase 3 activation in neonatal bornavirus infection. Journal of virology. vol 82. issue 4. 2008-03-05. PMID:18057239. |
infection of neonatal rats with borna disease virus results in a characteristic behavioral syndrome and apoptosis of subsets of neurons in the hippocampus, cerebellum, and cortex (neonatal borna disease [nbd]). |
2008-03-05 |
2023-08-12 |
rat |
| Takuya Watanabe, Katsunori Iwasaki, Shin Ishikane, Tetsuya Naitou, Yoshitaka Yoshimitsu, Norito Yamagata, Mehmeto Bülent Ozdemir, Kotaro Takasaki, Nobuaki Egashira, Kenichi Mishima, Michihiro Fujiwar. Spatial memory impairment without apoptosis induced by the combination of beta-amyloid oligomers and cerebral ischemia is related to decreased acetylcholine release in rats. Journal of pharmacological sciences. vol 106. issue 1. 2008-03-04. PMID:18187922. |
in the present study, the combination of abeta oligomers and cerebral ischemia, but not cerebral ischemia alone, significantly impaired spatial memory without apoptosis in the ca1 region of the hippocampus. |
2008-03-04 |
2023-08-12 |
rat |