| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhe Cheng, Haiquan Zhao, Yuguan Ze, Junju Su, Bing Li, Lei Sheng, Liyuan Zhu, Ning Guan, Suxin Gui, Xuezi Sang, Xiaoyang Zhao, Qingqing Sun, Ling Wang, Jie Cheng, Renping Hu, Fashui Hon. Gene-expression changes in cerium chloride-induced injury of mouse hippocampus. PloS one. vol 8. issue 4. 2013-10-22. PMID:23573234. |
our findings suggested that exposure to cecl(3) led to hippocampal lesions, apoptosis, oxidative stress and impairment of spatial recognition memory. |
2013-10-22 |
2023-08-12 |
mouse |
| Matthew E Pamenter, Guy A Perkins, Xiang Q Gu, Mark H Ellisman, Gabriel G Hadda. DIDS (4,4-diisothiocyanatostilbenedisulphonic acid) induces apoptotic cell death in a hippocampal neuronal cell line and is not neuroprotective against ischemic stress. PloS one. vol 8. issue 4. 2013-10-22. PMID:23577164. |
we conclude that dids induces apoptosis in cultured hippocampal neurons, in spite of the fact that some common hallmarks of cell death pathways are prevented. |
2013-10-22 |
2023-08-12 |
Not clear |
| María Irene Ayuso, Emma Martínez-Alonso, Cristina Cid, Maria Alonso de Leciñana, Alberto Alcáza. The translational repressor eIF4E-binding protein 2 (4E-BP2) correlates with selective delayed neuronal death after ischemia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 33. issue 8. 2013-10-22. PMID:23591646. |
upon reperfusion, a selective neuronal apoptosis in the hippocampal cornu ammonis 1 (ca1) region was induced, while it did not occur in the cerebral cortex. |
2013-10-22 |
2023-08-12 |
rat |
| Bo-Kyun Kim, Il-Gyu Ko, Sung-Eun Kim, Chang-Ju Kim, Jee-Sang Yoon, Hyung-Hwan Baik, Byung-Kwan Jin, Choong-Yeol Lee, Sang-Bin Baek, Mal-Soon Shi. Impact of Several Types of Stresses on Short-term Memory and Apoptosis in the Hippocampus of Rats. International neurourology journal. vol 17. issue 3. 2013-10-21. PMID:24143289. |
impact of several types of stresses on short-term memory and apoptosis in the hippocampus of rats. |
2013-10-21 |
2023-08-12 |
rat |
| R Krolow, C Noschang, D M Arcego, L F Pettenuzzo, S N Weis, M L Marcolin, A P Huffell, C S Mota, C Dalma. Isolation stress exposure and consumption of palatable diet during the prepubertal period leads to cellular changes in the hippocampus. Neurochemical research. vol 38. issue 2. 2013-10-17. PMID:23132740. |
for this, we evaluated oxidative stress parameters, dna breakage index, mitochondrial mass and potential, respiratory chain enzyme activities, apoptosis, and necrosis in the hippocampus of juvenile male rats submitted or not to isolation stress during the pre-puberty period. |
2013-10-17 |
2023-08-12 |
rat |
| R Krolow, C Noschang, D M Arcego, L F Pettenuzzo, S N Weis, M L Marcolin, A P Huffell, C S Mota, C Dalma. Isolation stress exposure and consumption of palatable diet during the prepubertal period leads to cellular changes in the hippocampus. Neurochemical research. vol 38. issue 2. 2013-10-17. PMID:23132740. |
in conclusion, the stress experienced during the pre-pubertal period induced a hippocampal oxidative imbalance, dna damage, mitochondrial dysfunction, and increased apoptosis, while consumption of a palatable diet attenuated some of these effects of exposure, such as the reduction in live cells and increased apoptosis, besides favoring an increase in antioxidant enzymes activities. |
2013-10-17 |
2023-08-12 |
rat |
| Phullara B Shelat, Leigh D Plant, Janice C Wang, Elizabeth Lee, Jeremy D Mark. The membrane-active tri-block copolymer pluronic F-68 profoundly rescues rat hippocampal neurons from oxygen-glucose deprivation-induced death through early inhibition of apoptosis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 30. 2013-10-17. PMID:23884935. |
the membrane-active tri-block copolymer pluronic f-68 profoundly rescues rat hippocampal neurons from oxygen-glucose deprivation-induced death through early inhibition of apoptosis. |
2013-10-17 |
2023-08-12 |
rat |
| Phullara B Shelat, Leigh D Plant, Janice C Wang, Elizabeth Lee, Jeremy D Mark. The membrane-active tri-block copolymer pluronic F-68 profoundly rescues rat hippocampal neurons from oxygen-glucose deprivation-induced death through early inhibition of apoptosis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 30. 2013-10-17. PMID:23884935. |
here, we demonstrate the efficacy of pluronic f-68 in rescuing rat hippocampal neurons from apoptosis after oxygen-glucose deprivation (ogd). |
2013-10-17 |
2023-08-12 |
rat |
| Zhengwu Peng, Ruiguo Zhang, Huaning Wang, Yunchun Chen, Fen Xue, Lei Wang, Fan Yang, Yihuan Chen, Ling Liu, Fang Kuang, Qingrong Ta. Ziprasidone ameliorates anxiety-like behaviors in a rat model of PTSD and up-regulates neurogenesis in the hippocampus and hippocampus-derived neural stem cells. Behavioural brain research. vol 244. 2013-09-30. PMID:23384713. |
one possible explanation is that the neuroprotective and neurogenetic actions of ziprasidone can attenuate the neuronal apoptosis which occurs in the hippocampus. |
2013-09-30 |
2023-08-12 |
rat |
| Subhash Dwivedi, Rajasekar Nagarajan, Kashif Hanif, Hefazat Husain Siddiqui, Chandishwar Nath, Rakesh Shukl. Standardized Extract of Bacopa monniera Attenuates Okadaic Acid Induced Memory Dysfunction in Rats: Effect on Nrf2 Pathway. Evidence-based complementary and alternative medicine : eCAM. vol 2013. 2013-09-30. PMID:24078822. |
rats were sacrificed for biochemical estimations of oxidative stress, neuroinflammation, apoptosis, and molecular studies of nrf2, ho1, and gclc expressions in cerebral cortex and hippocampus brain regions. |
2013-09-30 |
2023-08-12 |
rat |
| Muhammad Imran Naseer, Ikram Ullah, Mohammed H Al-Qahtani, Sajjad Karim, Najeeb Ullah, Shakeel Ahmed Ansari, Myeong Ok Kim, Fehmida Bib. Decreased GABABR expression and increased neuronal cell death in developing rat brain after PTZ-induced seizure. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 34. issue 4. 2013-09-26. PMID:22484544. |
the results of the present study showed that ptz-induced seizure significantly decreased gababr expression and induced neuronal apoptosis in cortical and hippocampal part of brain. |
2013-09-26 |
2023-08-12 |
rat |
| Li Hu, Jia Liang, Shu-Ying Jin, Yan-Jing Han, Jun Lu, Ya T. [Progress of researches on mechanisms of acupuncture underlying improvement of depression in the past five years]. Zhen ci yan jiu = Acupuncture research. vol 38. issue 3. 2013-09-24. PMID:24006675. |
; 2) upregulating expression of hippocampal brain-derived neurotrophic factor protein and mrna and its receptor trkb, and activating adenyl cyclase-camp-pka-creb signaling pathway; 3) increasing hippocampal growth-associated protein 43 level and suppressing hippocampal c-jun n-terminal kinase activation and cellular apoptosis; 4) upregulating expression of glial fibrillary acidic protein (activating glia cells); 5) regulating activities of hypothalamus-pituitary-adrenal axis and hypothalamus-pituitary-sex gland axis; 6) down-regulating serum il-1beta, il-6, and tumor necrosis factor-alpha levels. |
2013-09-24 |
2023-08-12 |
Not clear |
| Xu Zhang, Patrick K K Yeung, Grainne M McAlonan, Stephen S M Chung, Sookja K Chun. Transgenic mice over-expressing endothelial endothelin-1 show cognitive deficit with blood-brain barrier breakdown after transient ischemia with long-term reperfusion. Neurobiology of learning and memory. vol 101. 2013-09-09. PMID:23313614. |
parallel with these behavioral changes, tet-1 mice showed more severe brain damage with blood-brain-barrier breakdown (bbb), reactive astrogliosis, increased caspase-3, and increased peroxiredoxin 6 (prx6) expressions around blood vessels in the ipsilateral hippocampus, compared to that of ntg mice, suggesting that et-1 over-expression in the endothelial cells leads to more severe bbb breakdown and increased oxidative stress which may resulted in neuronal apoptosis and glial reactivity, which might contribute to the emotional changes and cognitive deficits after short-term ischemia with long-term reperfusion. |
2013-09-09 |
2023-08-12 |
mouse |
| Yan Long, Yubang Wang, Guixiang Ji, Lifeng Yan, Fan Hu, Aihua G. Neurotoxicity of perfluorooctane sulfonate to hippocampal cells in adult mice. PloS one. vol 8. issue 1. 2013-09-04. PMID:23382877. |
significant apoptosis was found in hippocampal cells after pfos exposure, accompanied with a increase of glutamate in the hippocampus and decreases of dopamine (da) and 3,4-dihydrophenylacetic acid (dopac) in caudate putamen in the 10.75 mg/kg pfos group. |
2013-09-04 |
2023-08-12 |
mouse |
| Mal-Soon Shin, Il-Gyu Ko, Sung-Eun Kim, Bo-Kyun Kim, Tae-Soo Kim, Shin-Ho Lee, Dong-Sup Hwang, Chang-Ju Kim, Jin-Kook Park, Baek-Vin Li. Treadmill exercise ameliorates symptoms of methimazole-induced hypothyroidism through enhancing neurogenesis and suppressing apoptosis in the hippocampus of rat pups. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 31. issue 3. 2013-08-30. PMID:23328696. |
treadmill exercise ameliorates symptoms of methimazole-induced hypothyroidism through enhancing neurogenesis and suppressing apoptosis in the hippocampus of rat pups. |
2013-08-30 |
2023-08-12 |
rat |
| Mal-Soon Shin, Il-Gyu Ko, Sung-Eun Kim, Bo-Kyun Kim, Tae-Soo Kim, Shin-Ho Lee, Dong-Sup Hwang, Chang-Ju Kim, Jin-Kook Park, Baek-Vin Li. Treadmill exercise ameliorates symptoms of methimazole-induced hypothyroidism through enhancing neurogenesis and suppressing apoptosis in the hippocampus of rat pups. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 31. issue 3. 2013-08-30. PMID:23328696. |
induction of hypothyroidism during the fetal and early postnatal period showed suppression of neurogenesis and enhancement of apoptosis in the hippocampus. |
2013-08-30 |
2023-08-12 |
rat |
| Gang Chen, Ming Gong, Min Yan, Xiaoming Zhan. Sevoflurane induces endoplasmic reticulum stress mediated apoptosis in hippocampal neurons of aging rats. PloS one. vol 8. issue 2. 2013-08-29. PMID:23469093. |
sevoflurane induces endoplasmic reticulum stress mediated apoptosis in hippocampal neurons of aging rats. |
2013-08-29 |
2023-08-12 |
rat |
| Gang Chen, Ming Gong, Min Yan, Xiaoming Zhan. Sevoflurane induces endoplasmic reticulum stress mediated apoptosis in hippocampal neurons of aging rats. PloS one. vol 8. issue 2. 2013-08-29. PMID:23469093. |
therefore we hypothesized that er stress mediated hippocampal neurons apoptosis might play an important role in the mechanism of sevoflurane-induced cognitive impairment in aged rats. |
2013-08-29 |
2023-08-12 |
rat |
| Xiaoqiang Tian, Lida Zhang, Jingmei Wang, Jianguo Dai, Shanshan Shen, Lin Yang, Peilin Huan. The protective effect of hyperbaric oxygen and Ginkgo biloba extract on Aβ25-35-induced oxidative stress and neuronal apoptosis in rats. Behavioural brain research. vol 242. 2013-08-27. PMID:23266522. |
the activities of sod and gsh, the apoptosis-related genes and proteins and the apoptosis rate of hippocampus were detected. |
2013-08-27 |
2023-08-12 |
human |
| Chun-I Sze, Yung-Chieh Lin, Yuh-Jyh Lin, Ting-Hui Hsieh, Yu Min Kuo, Chyi-Her Li. The role of glucocorticoid receptors in dexamethasone-induced apoptosis of neuroprogenitor cells in the hippocampus of rat pups. Mediators of inflammation. vol 2013. 2013-08-19. PMID:23401645. |
the role of glucocorticoid receptors in dexamethasone-induced apoptosis of neuroprogenitor cells in the hippocampus of rat pups. |
2013-08-19 |
2023-08-12 |
rat |