| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lingzhi Sun, Weiduan Zhuang, Xiangqing Xu, Jun Yang, Jing Teng, Fengxia Zhan. The effect of injection of EGb 761 into the lateral ventricle on hippocampal cell apoptosis and stem cell stimulation in situ of the ischemic/reperfusion rat model. Neuroscience letters. vol 555. 2014-01-31. PMID:24036465. |
the effect of injection of egb 761 into the lateral ventricle on hippocampal cell apoptosis and stem cell stimulation in situ of the ischemic/reperfusion rat model. |
2014-01-31 |
2023-08-12 |
rat |
| Lingzhi Sun, Weiduan Zhuang, Xiangqing Xu, Jun Yang, Jing Teng, Fengxia Zhan. The effect of injection of EGb 761 into the lateral ventricle on hippocampal cell apoptosis and stem cell stimulation in situ of the ischemic/reperfusion rat model. Neuroscience letters. vol 555. 2014-01-31. PMID:24036465. |
infarct volume, as revealed by 1% 2,3,5-triphenyltetrazolium chloride (ttc) staining, was significantly reduced, coupled with conspicuous suppression of neurons apoptosis and significant increments in the cell proliferation and migration in hippocampus. |
2014-01-31 |
2023-08-12 |
rat |
| Masashi Okada, Yasukazu Hozumi, Toshiaki Tanaka, Yusuke Suzuki, Mitsuaki Yanagida, Yoshihiko Araki, Camilla Evangelisti, Hitoshi Yagisawa, Matthew K Topham, Alberto M Martelli, Kaoru Got. DGKζ is degraded through the cytoplasmic ubiquitin-proteasome system under excitotoxic conditions, which causes neuronal apoptosis because of aberrant cell cycle reentry. Cellular signalling. vol 24. issue 8. 2014-01-30. PMID:22516102. |
collectively, these results suggest that 1) glutamate excitotoxicity induces nucleocytoplasmic translocation of dgkζ followed by its degradation through the cytoplasmic ups in hippocampal neurons and that 2) dgkζ-deficient neurons do not succumb directly to apoptosis, although they are more vulnerable to excitotoxicity because of aberrant cell cycle reentry. |
2014-01-30 |
2023-08-12 |
mouse |
| Hong Liu, Fang Han, Yuxiu Sh. Effect of calreticulin on Ca2+/CaM kinaseIIα and endoplasmic reticulum stress in hippocampal in a rat model of post-traumatic stress disorder. Neurochemical research. vol 38. issue 7. 2014-01-24. PMID:23575574. |
therefore, we propose that the hippocampal apoptosis could be one of the pathological mechanisms related to the memory disorders in ptsd. |
2014-01-24 |
2023-08-12 |
rat |
| Ke-Ping Ye, Chun-Ru Chen, Jin-Wei Zheng, Hong Cao, Bin Ji, Rui Zhou, Zhi-Yan Meng, Jun Li, Qing-Quan Lia. [Effect of curcumine on the nuclear pathway of JNK during hippocampal ischemia/reperfusion injury in SHR]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 26. issue 4. 2014-01-23. PMID:21328975. |
to investigate the diversify of the nuclear pathway of c-jun nh2-terminal kinases (jnk) during transient brain ischemia/reperfusion injury in hippocampal neuron apoptosis in spontaneously hypertensive rats (shr) and to test whether the neuroprotection of curcumine on transient brain ischemia/reperfusion injury in shr is related to the nuclear pathway of jnk. |
2014-01-23 |
2023-08-12 |
rat |
| Hong Wang, Marjorie C Gondré-Lewi. Prenatal nicotine and maternal deprivation stress de-regulate the development of CA1, CA3, and dentate gyrus neurons in hippocampus of infant rats. PloS one. vol 8. issue 6. 2014-01-21. PMID:23785432. |
these results suggest that early stressors may modulate neurogenesis, apoptosis, or maturation of glutamatergic neurons in the hippocampus in a region-specific manner during critical periods of neurodevelopment. |
2014-01-21 |
2023-08-12 |
rat |
| Mohammad Amin Sherafat, Abdolaziz Ronaghi, Leila Ahmad-Molaei, Mohammad Nejadhoseynian, Rasoul Ghasemi, Arman Hosseini, Nima Naderi, Fereshteh Motamed. Kindling-induced learning deficiency and possible cellular and molecular involved mechanisms. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 34. issue 6. 2014-01-17. PMID:22744648. |
the results suggested that the decrease in learning and memory in kindled animals is likely due to demyelination and augmentation in apoptosis rate accompanied by inflammatory reaction in hippocampal neurons of kindled rats. |
2014-01-17 |
2023-08-12 |
rat |
| Yushu Dong, Yue Li, Dayun Feng, Julei Wang, Hua Wen, Debao Liu, Dandan Zhao, Haiying Liu, Guodong Gao, Zhongmin Yin, Huaizhou Qi. Protective effect of HIF-1α against hippocampal apoptosis and cognitive dysfunction in an experimental rat model of subarachnoid hemorrhage. Brain research. vol 1517. 2014-01-17. PMID:23608228. |
protective effect of hif-1α against hippocampal apoptosis and cognitive dysfunction in an experimental rat model of subarachnoid hemorrhage. |
2014-01-17 |
2023-08-12 |
rat |
| Yushu Dong, Yue Li, Dayun Feng, Julei Wang, Hua Wen, Debao Liu, Dandan Zhao, Haiying Liu, Guodong Gao, Zhongmin Yin, Huaizhou Qi. Protective effect of HIF-1α against hippocampal apoptosis and cognitive dysfunction in an experimental rat model of subarachnoid hemorrhage. Brain research. vol 1517. 2014-01-17. PMID:23608228. |
the aim of the present study was to investigate the expression of hif-1α in the hippocampus and its possible protective effect against hippocampal apoptosis and cognitive dysfunction in a rat model of sah. |
2014-01-17 |
2023-08-12 |
rat |
| Yushu Dong, Yue Li, Dayun Feng, Julei Wang, Hua Wen, Debao Liu, Dandan Zhao, Haiying Liu, Guodong Gao, Zhongmin Yin, Huaizhou Qi. Protective effect of HIF-1α against hippocampal apoptosis and cognitive dysfunction in an experimental rat model of subarachnoid hemorrhage. Brain research. vol 1517. 2014-01-17. PMID:23608228. |
these results indicate that hippocampal apoptosis increased and cognitive function deteriorated when hif-1α was inhibited, suggesting that hif-1α has a neuroprotective effect in sah and may represent an effective therapeutic target. |
2014-01-17 |
2023-08-12 |
rat |
| M Jahanshahi, E G Nickmahzar, F Babakord. Effect of Gingko biloba extract on scopolamine-induced apoptosis in the hippocampus of rats. Anatomical science international. vol 88. issue 4. 2014-01-16. PMID:23828103. |
effect of gingko biloba extract on scopolamine-induced apoptosis in the hippocampus of rats. |
2014-01-16 |
2023-08-12 |
rat |
| M Jahanshahi, E G Nickmahzar, F Babakord. Effect of Gingko biloba extract on scopolamine-induced apoptosis in the hippocampus of rats. Anatomical science international. vol 88. issue 4. 2014-01-16. PMID:23828103. |
whereas, ginkgo biloba extract reduce the neuronal apoptosis in the hippocampus before and/or after encounter with scopolamine. |
2014-01-16 |
2023-08-12 |
rat |
| M Jahanshahi, E G Nickmahzar, F Babakord. Effect of Gingko biloba extract on scopolamine-induced apoptosis in the hippocampus of rats. Anatomical science international. vol 88. issue 4. 2014-01-16. PMID:23828103. |
we concluded that pretreatment and treatment injection of ginkgo biloba extract can have a protective effect for neurons and it can limit apoptosis in all area of the hippocampus. |
2014-01-16 |
2023-08-12 |
rat |
| Andréia Gomes Bezerra, Soraya Soubhi Smaili, Guiomar Silva Lopes, Elisaldo Araújo Carlin. Effects of Panax ginseng, Turnera diffusa and Heteropterys tomentosa extracts on hippocampal apoptosis of aged rats. Einstein (Sao Paulo, Brazil). vol 11. issue 2. 2014-01-15. PMID:23843055. |
effects of panax ginseng, turnera diffusa and heteropterys tomentosa extracts on hippocampal apoptosis of aged rats. |
2014-01-15 |
2023-08-12 |
rat |
| Ming-Chao Liu, Yan Xu, Yao-Ming Chen, Juan Li, Fang Zhao, Gang Zheng, Jin-Fei Jing, Tao Ke, Jing-Yuan Chen, Wen-Jing Lu. The effect of sodium selenite on lead induced cognitive dysfunction. Neurotoxicology. vol 36. 2014-01-13. PMID:23529067. |
the levels of hippocampal ltp, the spatial memory, the apoptosis of hippocampal neurons, the levels of lactate dehydrogenase (ldh) release, and the serum level of superoxide dismutase (sod) and malondialdehyde (mda) were assayed. |
2014-01-13 |
2023-08-12 |
rat |
| Fatemeh Mohagheghi, Abolhassan Ahmadiani, Behrouz Rahmani, Fatemeh Moradi, Nathalie Romond, Leila Khala. Gemfibrozil pretreatment resulted in a sexually dimorphic outcome in the rat models of global cerebral ischemia-reperfusion via modulation of mitochondrial pro-survival and apoptotic cell death factors as well as MAPKs. Journal of molecular neuroscience : MN. vol 50. issue 3. 2014-01-10. PMID:23288702. |
gemfibrozil also proved to be neuroprotective in met-estrous females, as it inhibited caspase-dependent apoptosis while in males it led to hippocampal neurodegeneration via activation of both the caspase-dependent and caspase-independent apoptosis. |
2014-01-10 |
2023-08-12 |
rat |
| Eduardo Blanco-Calvo, Patricia Rivera, Sergio Arrabal, Antonio Vargas, Francisco Javier Pavón, Antonia Serrano, Estela Castilla-Ortega, Pablo Galeano, Leticia Rubio, Juan Suárez, Fernando Rodriguez de Fonsec. Pharmacological blockade of either cannabinoid CB1 or CB2 receptors prevents both cocaine-induced conditioned locomotion and cocaine-induced reduction of cell proliferation in the hippocampus of adult male rat. Frontiers in integrative neuroscience. vol 7. 2014-01-10. PMID:24409127. |
additionally, we measured cell apoptosis (as monitored by the expression of cleaved caspase-3) and glial activation [by analyzing the expression of glial fibrillary acidic protein (gfap) and iba-1] in the striatum and hippocampus during acute and repeated (4 days) cocaine administration (20 mg/kg). |
2014-01-10 |
2023-08-12 |
rat |
| Nanchang Xie, Cui Wang, Yajun Lian, Haifeng Zhang, Chuanjie Wu, Qian Zhan. A selective inhibitor of Drp1, mdivi-1, protects against cell death of hippocampal neurons in pilocarpine-induced seizures in rats. Neuroscience letters. vol 545. 2014-01-06. PMID:23628672. |
altogether, our data suggested that mdivi-1 exerts neuroprotective effects against cell death of hippocampal neurons induced by seizures, and the underlying mechanism may be through inhibiting cytc release, aif translocation and suppression of the mitochondrial apoptosis pathway. |
2014-01-06 |
2023-08-12 |
rat |
| Xiaoming Zhang, Linhao Xu, Daqiang He, Shucai Lin. Endoplasmic reticulum stress-mediated hippocampal neuron apoptosis involved in diabetic cognitive impairment. BioMed research international. vol 2013. 2013-12-31. PMID:23710464. |
endoplasmic reticulum stress-mediated hippocampal neuron apoptosis involved in diabetic cognitive impairment. |
2013-12-31 |
2023-08-12 |
rat |
| Xiaoming Zhang, Linhao Xu, Daqiang He, Shucai Lin. Endoplasmic reticulum stress-mediated hippocampal neuron apoptosis involved in diabetic cognitive impairment. BioMed research international. vol 2013. 2013-12-31. PMID:23710464. |
the present results suggested that the chop-dependent endoplasmic reticulum (er) stress-mediated apoptosis may be involved in hyperglycemia-induced hippocampal synapses and neurons impairment and promote the diabetic cognitive impairment. |
2013-12-31 |
2023-08-12 |
rat |