| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kimikazu Fujita, Nobuko Yoshimoto, Toshiaki Kato, Hideki Imada, Gaku Matsumoto, Takahiro Inakuma, Yutaka Nagata, Eiichi Miyach. Lycopene inhibits ischemia/reperfusion-induced neuronal apoptosis in gerbil hippocampal tissue. Neurochemical research. vol 38. issue 3. 2013-08-15. PMID:23296626. |
lycopene inhibits ischemia/reperfusion-induced neuronal apoptosis in gerbil hippocampal tissue. |
2013-08-15 |
2023-08-12 |
Not clear |
| Zhong-Yan Zhao, Ping Luan, Shi-Xiong Huang, Song-Hua Xiao, Jia Zhao, Bei Zhang, Bei-Bei Gu, Rong-Biao Pi, Jun Li. Edaravone protects HT22 neurons from H2O2-induced apoptosis by inhibiting the MAPK signaling pathway. CNS neuroscience & therapeutics. vol 19. issue 3. 2013-08-14. PMID:23253171. |
this study aimed to investigate the effects and their underlying mechanism(s) of edaravone upon hydrogen peroxide (h2o2)-induced oxidative stress and apoptosis in ht22 cells, a murine hippocampal neuronal model. |
2013-08-14 |
2023-08-12 |
Not clear |
| Ghorbangol Ashabi, Shabnam Zeighamy Alamdary, Mahmoudreza Ramin, Fariba Khodaghol. Reduction of hippocampal apoptosis by intracerebroventricular administration of extracellular signal-regulated protein kinase and/or p38 inhibitors in amyloid beta rat model of Alzheimer's disease: involvement of nuclear-related factor-2 and nuclear factor-κB. Basic & clinical pharmacology & toxicology. vol 112. issue 3. 2013-08-05. PMID:22913737. |
reduction of hippocampal apoptosis by intracerebroventricular administration of extracellular signal-regulated protein kinase and/or p38 inhibitors in amyloid beta rat model of alzheimer's disease: involvement of nuclear-related factor-2 and nuclear factor-κb. |
2013-08-05 |
2023-08-12 |
rat |
| Suli Wei, Zhiqiang Xu, Junying Gao, Jiong Ding, Ming Xia. Prenatal ethanol exposure does not cause neurological alterations in adult CD1 mice. Neuroreport. vol 24. issue 4. 2013-07-29. PMID:23340320. |
consistently, pathological changes, such as increased neuronal apoptosis, decreased synaptic protein synaptophysin expression, synaptic loss and reactive astrogliosis, were not observed in the hippocampus of mice prenatally exposed to ethanol. |
2013-07-29 |
2023-08-12 |
mouse |
| X Yang, S Wang, Y Lin, Y Han, X Qiu, X Zhao, L Cao, X Wang, Z Ch. Poly(ADP-ribose) polymerase inhibition protects epileptic hippocampal neurons from apoptosis via suppressing Akt-mediated apoptosis-inducing factor translocation in vitro. Neuroscience. vol 231. 2013-07-25. PMID:23201256. |
poly(adp-ribose) polymerase inhibition protects epileptic hippocampal neurons from apoptosis via suppressing akt-mediated apoptosis-inducing factor translocation in vitro. |
2013-07-25 |
2023-08-12 |
Not clear |
| C Lin, C-J Wu, I-H Wei, M-H Tsai, N-W Chang, T-T Yang, Y-M Ku. Chronic treadmill running protects hippocampal neurons from hypobaric hypoxia-induced apoptosis in rats. Neuroscience. vol 231. 2013-07-25. PMID:23219906. |
chronic treadmill running protects hippocampal neurons from hypobaric hypoxia-induced apoptosis in rats. |
2013-07-25 |
2023-08-12 |
rat |
| F Lu, Y-Q Li, I Aubert, C S Won. Endothelial cells regulate p53-dependent apoptosis of neural progenitors after irradiation. Cell death & disease. vol 3. 2013-07-23. PMID:22717579. |
npcs transplanted into the hippocampus of smpd1-/- mice were protected against apoptosis after irradiation compared with those transplanted into smpd1+/+ mice. |
2013-07-23 |
2023-08-12 |
mouse |
| Jinghua Yang, Qiufang Liu, Shengwen Wu, Qi Xi, Yuan Ca. Effects of lanthanum chloride on glutamate level, intracellular calcium concentration and caspases expression in the rat hippocampus. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. vol 26. issue 1. 2013-07-12. PMID:23097080. |
these results indicate that lacl(3) increases glutamate level, [ca(2+)](i) and ratio of bax and bcl-2 expression, which cause excessive apoptosis by the mitochondrial and endoplasmic reticulum stress-induced pathway, and thus neuronal damages in the hippocampus. |
2013-07-12 |
2023-08-12 |
rat |
| Sandeep Gupta, Reshma Maurya, Monika Saxena, Jonaki Se. Defining structural homology between the mammalian and avian hippocampus through conserved gene expression patterns observed in the chick embryo. Developmental biology. vol 366. issue 2. 2013-07-05. PMID:22537492. |
we have identified the time window of neurogenesis and apoptosis during hippocampal development as well as the likely origin and migration path of neurons of the ventral v-shaped region of chick hippocampus. |
2013-07-05 |
2023-08-12 |
mouse |
| U R Goonetilleke, S A Ward, S B Gordo. Could proteomic research deliver the next generation of treatments for pneumococcal meningitis? Interdisciplinary perspectives on infectious diseases. vol 2009. 2013-07-04. PMID:19503804. |
animal models have added greatly to our knowledge of possible mechanisms and shown that hippocampal apoptosis and cortical necrosis are distinct mechanisms of neuronal death. |
2013-07-04 |
2023-08-12 |
human |
| Fariba Khodagholi, Ghorbangol Ashab. Dietary supplementation with Salvia sahendica attenuates memory deficits, modulates CREB and its down-stream molecules and decreases apoptosis in amyloid beta-injected rats. Behavioural brain research. vol 241. 2013-07-01. PMID:23201360. |
moreover, we used terminal-transferase dutp nick end labeling (tunel) technique to detect apoptosis in the hippocampus of aβ-injected rats. |
2013-07-01 |
2023-08-12 |
rat |
| Carmen Silva-Alvarez, Macarena S Arrázola, Juan A Godoy, Daniela Ordenes, Nibaldo C Inestros. Canonical Wnt signaling protects hippocampal neurons from Aβ oligomers: role of non-canonical Wnt-5a/Ca(2+) in mitochondrial dynamics. Frontiers in cellular neuroscience. vol 7. 2013-06-28. PMID:23805073. |
we report here, that indirect activation of canonical wnt/β-catenin signaling using bromoindirubin-30-oxime (6-bio), an inhibitor of glycogen synthase kinase-3β, protects hippocampal neurons from amyloid-β (aβ) oligomers with the concomitant blockade of neuronal apoptosis. |
2013-06-28 |
2023-08-12 |
Not clear |
| Ruiyun Zhang, Guanglu Yang, Qingyi Wang, Feng Guo, Hua Wan. Acylated ghrelin protects hippocampal neurons in pilocarpine-induced seizures of immature rats by inhibiting cell apoptosis. Molecular biology reports. vol 40. issue 1. 2013-06-14. PMID:23129314. |
acylated ghrelin protects hippocampal neurons in pilocarpine-induced seizures of immature rats by inhibiting cell apoptosis. |
2013-06-14 |
2023-08-12 |
rat |
| Xin Li Xiao, Dong Liang Ma, Jing Wu, Feng-Ru Tan. Metabotropic glutamate receptor 5 (mGluR5) regulates proliferation and differentiation of neuronal progenitors in the developmental hippocampus. Brain research. vol 1493. 2013-06-13. PMID:23165119. |
western blot study suggested that programmed neuronal death was p53-dependent apoptosis in the developmental hippocampus in mglur5(+/+) mice. |
2013-06-13 |
2023-08-12 |
mouse |
| Xiao-Qing Tang, Yuan-Yuan Zhuang, Ping Zhang, Heng-Rong Fang, Cheng-Fang Zhou, Hong-Feng Gu, Hui Zhang, Chun-Yan Wan. Formaldehyde impairs learning and memory involving the disturbance of hydrogen sulfide generation in the hippocampus of rats. Journal of molecular neuroscience : MN. vol 49. issue 1. 2013-06-12. PMID:23108488. |
we found that the intracerebroventricular injection of fa in rats impairs the function of learning and memory in the morris water maze and novel object recognition test and increases the formation of apoptosis and lipid peroxidation in the hippocampus. |
2013-06-12 |
2023-08-12 |
rat |
| Mark Dunleavy, Giovanni Provenzano, David C Henshall, Yuri Bozz. Kainic acid-induced seizures modulate Akt (SER473) phosphorylation in the hippocampus of dopamine D2 receptor knockout mice. Journal of molecular neuroscience : MN. vol 49. issue 1. 2013-06-12. PMID:23188702. |
thus, we propose that gsk-3β phosphorylation-mediated hippocampal cell survival may depend on akt (ser473) phosphorylation; loss of d2r-mediated signalling in the ca3 region of d2r-/- mice leads to reduced akt (ser473) phosphorylation rendering neurons more vulnerable to apoptosis. |
2013-06-12 |
2023-08-12 |
mouse |
| Paul G W Keddy, Kate Dunlop, Jordan Warford, Michel L Samson, Quinton R D Jones, H P Vasantha Rupasinghe, George S Robertso. Neuroprotective and anti-inflammatory effects of the flavonoid-enriched fraction AF4 in a mouse model of hypoxic-ischemic brain injury. PloS one. vol 7. issue 12. 2013-06-11. PMID:23251498. |
af4 pre-treatment enhanced mrna levels for pro-survival proteins such as x-linked inhibitor of apoptosis and erythropoietin following hi in the dorsal hippocampus and striatum, respectively. |
2013-06-11 |
2023-08-12 |
mouse |
| Hamid Kalalian-Moghaddam, Tourandokht Baluchnejadmojarad, Mehrdad Roghani, Fatemeh Goshadrou, Abdolaziz Ronagh. Hippocampal synaptic plasticity restoration and anti-apoptotic effect underlie berberine improvement of learning and memory in streptozotocin-diabetic rats. European journal of pharmacology. vol 698. issue 1-3. 2013-06-10. PMID:23099256. |
chronic diabetes mellitus initiates apoptosis and negatively affects synaptic plasticity in the hippocampus with ensuing impairments of learning and memory. |
2013-06-10 |
2023-08-12 |
rat |
| Ai-Min Sun, Chuan-Gang Li, Yong-Qing Han, Que-Ling Liu, Qiong Xia, Ya-Wei Yua. X-ray irradiation promotes apoptosis of hippocampal neurons through up-regulation of Cdk5 and p25. Cancer cell international. vol 13. issue 1. 2013-06-07. PMID:23688022. |
x-ray irradiation promotes apoptosis of hippocampal neurons through up-regulation of cdk5 and p25. |
2013-06-07 |
2023-08-12 |
Not clear |
| Ai-Min Sun, Chuan-Gang Li, Yong-Qing Han, Que-Ling Liu, Qiong Xia, Ya-Wei Yua. X-ray irradiation promotes apoptosis of hippocampal neurons through up-regulation of Cdk5 and p25. Cancer cell international. vol 13. issue 1. 2013-06-07. PMID:23688022. |
however, the roles of cdk5 in hippocampal apoptosis in response to x-ray irradiation have not been explored. |
2013-06-07 |
2023-08-12 |
Not clear |