| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiu-Juan Li, Li Jiang, Long Chen, Heng-Sheng Chen, Xin L. Neurotoxicity of dibutyl phthalate in brain development following perinatal exposure: a study in rats. Environmental toxicology and pharmacology. vol 36. issue 2. 2014-03-10. PMID:23736097. |
dbp exposure induced cell apoptosis in hippocampal neurons of these neonatal and immature animals, as evidenced by the increased number of tunel-positive and annexin v-propidium iodide (pi) positive cells and up-regulated caspase-3 activity. |
2014-03-10 |
2023-08-12 |
rat |
| Jiping Liu, Liang Feng, Dongying Ma, Minghua Zhang, Junfei Gu, Shuyuan Wang, Qiang Fu, Yu Song, Zhou Lan, Rong Qu, Shiping M. Neuroprotective effect of paeonol on cognition deficits of diabetic encephalopathy in streptozotocin-induced diabetic rat. Neuroscience letters. vol 549. 2014-03-06. PMID:23791853. |
immunohistochemistry and tunel staining showed that paeonol could attenuate apoptosis of neurons and caspase 3 expression, improve two neurotrophic factors bdnf and igf expressions, and also ameliorate aβ deposition in the hippocampus and cerebral cortex. |
2014-03-06 |
2023-08-12 |
rat |
| Fang Han, Shengnan Yan, YuXiu Sh. Single-prolonged stress induces endoplasmic reticulum-dependent apoptosis in the hippocampus in a rat model of post-traumatic stress disorder. PloS one. vol 8. issue 7. 2014-03-03. PMID:23894451. |
single-prolonged stress induces endoplasmic reticulum-dependent apoptosis in the hippocampus in a rat model of post-traumatic stress disorder. |
2014-03-03 |
2023-08-12 |
rat |
| Fang Han, Shengnan Yan, YuXiu Sh. Single-prolonged stress induces endoplasmic reticulum-dependent apoptosis in the hippocampus in a rat model of post-traumatic stress disorder. PloS one. vol 8. issue 7. 2014-03-03. PMID:23894451. |
our previous research indicated that apoptosis induced atrophy in the hippocampus of post-traumatic stress disorder (ptsd) rats. |
2014-03-03 |
2023-08-12 |
rat |
| Fang Han, Shengnan Yan, YuXiu Sh. Single-prolonged stress induces endoplasmic reticulum-dependent apoptosis in the hippocampus in a rat model of post-traumatic stress disorder. PloS one. vol 8. issue 7. 2014-03-03. PMID:23894451. |
the aim of this study was to investigate whether endoplasmic reticulum-related pathway is involved in single-prolonged stress (sps) induces apoptosis in the hippocampus of ptsd rats by examining the expression levels of three important indicators in the er-related apoptotic pathway: glucose-regulated protein (grp) 78, caspase-12 and ca(2+)/cam/camkinaseiiα (camkiiα). |
2014-03-03 |
2023-08-12 |
rat |
| R A Kireev, E Vara, J A F Tresguerre. Growth hormone and melatonin prevent age-related alteration in apoptosis processes in the dentate gyrus of male rats. Biogerontology. vol 14. issue 4. 2014-02-25. PMID:23852044. |
it has been suggested that the age-related decrease in the number of neurons in the hippocampus that leads to alterations in brain function, may be associated with an increase in apoptosis due to the reduced secretion of growth hormone (gh) and/or melatonin in old animals. |
2014-02-25 |
2023-08-12 |
rat |
| R A Kireev, E Vara, J A F Tresguerre. Growth hormone and melatonin prevent age-related alteration in apoptosis processes in the dentate gyrus of male rats. Biogerontology. vol 14. issue 4. 2014-02-25. PMID:23852044. |
both treatments were able to reduce apoptosis and to enhance survival markers in this part of the hippocampus. |
2014-02-25 |
2023-08-12 |
rat |
| Luana Heimfarth, Samanta Oliveira Loureiro, Paula Pierozan, Bárbara Ortiz de Lima, Karina Pires Reis, Elisandra Barbosa Torres, Regina Pessoa-Pureu. Methylglyoxal-induced cytotoxicity in neonatal rat brain: a role for oxidative stress and MAP kinases. Metabolic brain disease. vol 28. issue 3. 2014-02-24. PMID:23378107. |
in this study, we are showing, that mgo is able to suppress cell viability and induce apoptosis in the cerebral cortex and hippocampus of neonatal rats ex-vivo. |
2014-02-24 |
2023-08-12 |
rat |
| P F Jiang, T Zhu, J D Gao, F Gao, S S Mao, W T Zhao, W Z Gu, H M Y. The effect of maternal infection on cognitive development and hippocampus neuronal apoptosis, proliferation and differentiation in the neonatal rats. Neuroscience. vol 246. 2014-02-24. PMID:23597829. |
the effect of maternal infection on cognitive development and hippocampus neuronal apoptosis, proliferation and differentiation in the neonatal rats. |
2014-02-24 |
2023-08-12 |
rat |
| P F Jiang, T Zhu, J D Gao, F Gao, S S Mao, W T Zhao, W Z Gu, H M Y. The effect of maternal infection on cognitive development and hippocampus neuronal apoptosis, proliferation and differentiation in the neonatal rats. Neuroscience. vol 246. 2014-02-24. PMID:23597829. |
in this study, we discovered the effect of maternal infection to hippocampal neuronal apoptosis, proliferation and differentiation, and cognitive development in the developing brains of neonatal rats. |
2014-02-24 |
2023-08-12 |
rat |
| P F Jiang, T Zhu, J D Gao, F Gao, S S Mao, W T Zhao, W Z Gu, H M Y. The effect of maternal infection on cognitive development and hippocampus neuronal apoptosis, proliferation and differentiation in the neonatal rats. Neuroscience. vol 246. 2014-02-24. PMID:23597829. |
terminal deoxynucleotidyl transferase dutp nick end labeling assay was used to determine neuronal apoptosis, immunostaining was conducted to assess neurogenesis, and western blot for extracellular signal-regulated kinase (erk), cyclic amp responsive element-binding protein (creb) and brain-derived neurotrophic factor (bdnf) expression in the hippocampus. |
2014-02-24 |
2023-08-12 |
rat |
| P F Jiang, T Zhu, J D Gao, F Gao, S S Mao, W T Zhao, W Z Gu, H M Y. The effect of maternal infection on cognitive development and hippocampus neuronal apoptosis, proliferation and differentiation in the neonatal rats. Neuroscience. vol 246. 2014-02-24. PMID:23597829. |
maternal infection increased hippocampal neuronal apoptosis and affected cell proliferation and differentiation in neonatal rats, which may be regarded as an etiological factor in cognitive development impairment. |
2014-02-24 |
2023-08-12 |
rat |
| Amin Ataie, Ramin Ataee, Mohammad Shadifar, Sima Shahabi, Seyed Mohsen Aghajanpour, Younes Hosseinpou. Interaction of Memantine with Homocysteine on the Apoptosis in the Rat Hippocampus cells. International journal of molecular and cellular medicine. vol 1. issue 3. 2014-02-19. PMID:24551770. |
interaction of memantine with homocysteine on the apoptosis in the rat hippocampus cells. |
2014-02-19 |
2023-08-12 |
rat |
| Patricia Rivera, Margarita Pérez-Martín, Francisco J Pavón, Antonia Serrano, Ana Crespillo, Manuel Cifuentes, María-Dolores López-Ávalos, Jesús M Grondona, Margarita Vida, Pedro Fernández-Llebrez, Fernando Rodríguez de Fonseca, Juan Suáre. Pharmacological administration of the isoflavone daidzein enhances cell proliferation and reduces high fat diet-induced apoptosis and gliosis in the rat hippocampus. PloS one. vol 8. issue 5. 2014-02-18. PMID:23741384. |
pharmacological administration of the isoflavone daidzein enhances cell proliferation and reduces high fat diet-induced apoptosis and gliosis in the rat hippocampus. |
2014-02-18 |
2023-08-12 |
rat |
| Patricia Rivera, Margarita Pérez-Martín, Francisco J Pavón, Antonia Serrano, Ana Crespillo, Manuel Cifuentes, María-Dolores López-Ávalos, Jesús M Grondona, Margarita Vida, Pedro Fernández-Llebrez, Fernando Rodríguez de Fonseca, Juan Suáre. Pharmacological administration of the isoflavone daidzein enhances cell proliferation and reduces high fat diet-induced apoptosis and gliosis in the rat hippocampus. PloS one. vol 8. issue 5. 2014-02-18. PMID:23741384. |
in the present study we explore the effects of pharmacological administration of daidzein, a main soy isoflavone, in cell proliferation, cell apoptosis and gliosis in the adult hippocampus of animals exposed to a very high-fat diet. |
2014-02-18 |
2023-08-12 |
rat |
| Patricia Rivera, Margarita Pérez-Martín, Francisco J Pavón, Antonia Serrano, Ana Crespillo, Manuel Cifuentes, María-Dolores López-Ávalos, Jesús M Grondona, Margarita Vida, Pedro Fernández-Llebrez, Fernando Rodríguez de Fonseca, Juan Suáre. Pharmacological administration of the isoflavone daidzein enhances cell proliferation and reduces high fat diet-induced apoptosis and gliosis in the rat hippocampus. PloS one. vol 8. issue 5. 2014-02-18. PMID:23741384. |
then, plasma levels of metabolites and metabolic hormones, cell proliferation in the subgranular zone of the dentate gyrus (sgz), and immunohistochemical markers of hippocampal cell apoptosis (caspase-3), gliosis (gfap and iba-1), food reward factor fosb and estrogen receptor alpha (erα) were analyzed. |
2014-02-18 |
2023-08-12 |
rat |
| Shahid Ali Shah, Ikram Ullah, Hae Young Lee, Myeong Ok Ki. Anthocyanins protect against ethanol-induced neuronal apoptosis via GABAB1 receptors intracellular signaling in prenatal rat hippocampal neurons. Molecular neurobiology. vol 48. issue 1. 2014-02-12. PMID:23645118. |
anthocyanins protect against ethanol-induced neuronal apoptosis via gabab1 receptors intracellular signaling in prenatal rat hippocampal neurons. |
2014-02-12 |
2023-08-12 |
rat |
| Shahid Ali Shah, Ikram Ullah, Hae Young Lee, Myeong Ok Ki. Anthocyanins protect against ethanol-induced neuronal apoptosis via GABAB1 receptors intracellular signaling in prenatal rat hippocampal neurons. Molecular neurobiology. vol 48. issue 1. 2014-02-12. PMID:23645118. |
here, we investigated the possible involvement of gamma-aminobutyric acid b1 receptor (gabab1r) in mediating the protective effects of black soybean anthocyanins against ethanol-induced apoptosis in prenatal hippocampal neurons because gabars are known to play an important role in the development of central nervous system. |
2014-02-12 |
2023-08-12 |
rat |
| Jingjing Guo, Jianing Wang, Zhe Zhang, Jun Yan, Mingming Chen, Tao Pang, Luyong Zhang, Hong Lia. proNGF inhibits neurogenesis and induces glial activation in adult mouse dentate gyrus. Neurochemical research. vol 38. issue 8. 2014-02-06. PMID:23709363. |
prongf infusion also induced prominent cell apoptosis and activated residential astrocyte and microglia, which might further impair the hippocampal neurogenesis. |
2014-02-06 |
2023-08-12 |
mouse |
| Seung-Eon Roh, Jung A Woo, Madepalli K Lakshmana, Courtney Uhlar, Vinishaa Ankala, Taylor Boggess, Tian Liu, Yun-Hwa Hong, Inhee Mook-Jung, Sang Jeong Kim, David E Kan. Mitochondrial dysfunction and calcium deregulation by the RanBP9-cofilin pathway. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 27. issue 12. 2014-02-04. PMID:23982146. |
here we show in primary hippocampal neurons that ranbp9 potentiates aβ-induced reactive oxygen species (ros) overproduction, apoptosis, and calcium deregulation. |
2014-02-04 |
2023-08-12 |
mouse |