| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shen Yang, Guangan Zhou, Hong Liu, Bo Zhang, Juan Li, Ruiting Cui, Yifeng D. Protective effects of p38 MAPK inhibitor SB202190 against hippocampal apoptosis and spatial learning and memory deficits in a rat model of vascular dementia. BioMed research international. vol 2013. 2014-07-29. PMID:24455679. |
protective effects of p38 mapk inhibitor sb202190 against hippocampal apoptosis and spatial learning and memory deficits in a rat model of vascular dementia. |
2014-07-29 |
2023-08-12 |
rat |
| Shen Yang, Guangan Zhou, Hong Liu, Bo Zhang, Juan Li, Ruiting Cui, Yifeng D. Protective effects of p38 MAPK inhibitor SB202190 against hippocampal apoptosis and spatial learning and memory deficits in a rat model of vascular dementia. BioMed research international. vol 2013. 2014-07-29. PMID:24455679. |
in the present study, we examined the protective effects of p38 mapk inhibitor sb202190 against hippocampal apoptosis and spatial learning and memory deficits in a chronic hypoperfusion rat model of vad established by permanent bilateral carotid occlusion (2-vo). |
2014-07-29 |
2023-08-12 |
rat |
| Shen Yang, Guangan Zhou, Hong Liu, Bo Zhang, Juan Li, Ruiting Cui, Yifeng D. Protective effects of p38 MAPK inhibitor SB202190 against hippocampal apoptosis and spatial learning and memory deficits in a rat model of vascular dementia. BioMed research international. vol 2013. 2014-07-29. PMID:24455679. |
the sb202190 group also showed significantly reduced neuronal apoptosis in the hippocampus compared to vad model rats (p < 0.01) as well as higher (antiapoptotic) bcl-2 expression and lower (proapoptotic) caspase-3 expression (p < 0.01 for both). |
2014-07-29 |
2023-08-12 |
rat |
| Shen Yang, Guangan Zhou, Hong Liu, Bo Zhang, Juan Li, Ruiting Cui, Yifeng D. Protective effects of p38 MAPK inhibitor SB202190 against hippocampal apoptosis and spatial learning and memory deficits in a rat model of vascular dementia. BioMed research international. vol 2013. 2014-07-29. PMID:24455679. |
in conclusion, blockade of the p38 mapk signaling pathway by sb202190 following permanent 2-ov reduced apoptosis of hippocampal neurons and rescued spatial learning and memory deficits. |
2014-07-29 |
2023-08-12 |
rat |
| Mi-Sook Park, Hyean-Ae Oh, Il-Gyu Ko, Sung-Eun Kim, Sang-Hoon Kim, Chang-Ju Kim, Hyun-Bae Kim, Hong Ki. Influence of mild traumatic brain injury during pediatric stage on short-term memory and hippocampal apoptosis in adult rats. Journal of exercise rehabilitation. vol 10. issue 3. 2014-07-25. PMID:25061593. |
influence of mild traumatic brain injury during pediatric stage on short-term memory and hippocampal apoptosis in adult rats. |
2014-07-25 |
2023-08-13 |
rat |
| Mi-Sook Park, Hyean-Ae Oh, Il-Gyu Ko, Sung-Eun Kim, Sang-Hoon Kim, Chang-Ju Kim, Hyun-Bae Kim, Hong Ki. Influence of mild traumatic brain injury during pediatric stage on short-term memory and hippocampal apoptosis in adult rats. Journal of exercise rehabilitation. vol 10. issue 3. 2014-07-25. PMID:25061593. |
moreover, we investigated the influence of mild tbi on memory impairment in relation with hippocampal apoptosis. |
2014-07-25 |
2023-08-13 |
rat |
| Lei Xi, Jin Wang, Hui Zheng, Qun Wan. [Mechanism of cytoprotective effect of thyroid hormone on the hippocampus of rats with chronic cerebral ischemia]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 33. issue 5. 2014-07-24. PMID:23689003. |
to investigate the role of bcl-2 in the cytoprotective effect of thyroid hormone against hippocampal cell apoptosis in rats with chronic cerebral ischemia. |
2014-07-24 |
2023-08-12 |
rat |
| L An, Z Li, T Zhan. Reversible effects of vitamins C and E combination on oxidative stress-induced apoptosis in melamine-treated PC12 cells. Free radical research. vol 48. issue 2. 2014-07-24. PMID:24182201. |
previous studies showed that melamine-induced apoptosis and oxidative damage on pc12 cells and rats' hippocampus. |
2014-07-24 |
2023-08-12 |
rat |
| Eun-Ju Yang, Gyu Hwan Park, Kyung-Sik Son. Neuroprotective effects of liquiritigenin isolated from licorice roots on glutamate-induced apoptosis in hippocampal neuronal cells. Neurotoxicology. vol 39. 2014-07-23. PMID:24012889. |
neuroprotective effects of liquiritigenin isolated from licorice roots on glutamate-induced apoptosis in hippocampal neuronal cells. |
2014-07-23 |
2023-08-12 |
mouse |
| Hai-Yan Hu, Zhi-Hui Cui, Hui-Qin Li, Yi-Ru Wang, Xiang Chen, Ji-Huang Li, Dong-Mei Xv, Guo-Qing Zhen. Fumanjian, a Classic Chinese Herbal Formula, Can Ameliorate the Impairment of Spatial Learning and Memory through Apoptotic Signaling Pathway in the Hippocampus of Rats with Aβ 1-40 -Induced Alzheimer's Disease. Evidence-based complementary and alternative medicine : eCAM. vol 2014. 2014-07-22. PMID:25050129. |
apoptosis was tested using tunel staining in hippocampus neuronal cells; rt-pcr tested expression of bcl-2 and bax mrna; western blotting tested protein level of cleaved caspase-3. |
2014-07-22 |
2023-08-13 |
rat |
| Ye-Nan Chi, Xu Zhang, Jie Cai, Feng-Yu Liu, Guo-Gang Xing, You Wa. Formaldehyde increases intracellular calcium concentration in primary cultured hippocampal neurons partly through NMDA receptors and T-type calcium channels. Neuroscience bulletin. vol 28. issue 6. 2014-07-21. PMID:23160928. |
formaldehyde induces mis-folding and aggregation of neuronal tau protein, hippocampal neuronal apoptosis, cognitive impairment and loss of memory functions, as well as excitation of peripheral nociceptive neurons in cancer pain models. |
2014-07-21 |
2023-08-12 |
Not clear |
| Jianliang Chen, Xuesong Li, Jiandong Qiu, Hengxing You, Qingping Zhang, Guangyu Dong, You Zu. Kinetics of apoptosis and expression of apoptosis-related proteins in rat CA3 hippocampus cells after experimental diffuse brain injury. Cell biochemistry and biophysics. vol 67. issue 3. 2014-07-15. PMID:23559276. |
kinetics of apoptosis and expression of apoptosis-related proteins in rat ca3 hippocampus cells after experimental diffuse brain injury. |
2014-07-15 |
2023-08-12 |
rat |
| Jianliang Chen, Xuesong Li, Jiandong Qiu, Hengxing You, Qingping Zhang, Guangyu Dong, You Zu. Kinetics of apoptosis and expression of apoptosis-related proteins in rat CA3 hippocampus cells after experimental diffuse brain injury. Cell biochemistry and biophysics. vol 67. issue 3. 2014-07-15. PMID:23559276. |
the present study examined kinetics of apoptosis and expression of apoptosis-related proteins bcl-2, bax, and caspase-3 in the ca3 hippocampus cells after diffuse brain injury (dbi) induced experimentally in rats. |
2014-07-15 |
2023-08-12 |
rat |
| Jianliang Chen, Xuesong Li, Jiandong Qiu, Hengxing You, Qingping Zhang, Guangyu Dong, You Zu. Kinetics of apoptosis and expression of apoptosis-related proteins in rat CA3 hippocampus cells after experimental diffuse brain injury. Cell biochemistry and biophysics. vol 67. issue 3. 2014-07-15. PMID:23559276. |
substantial neuronal apoptosis was documented in the ca3 hippocampus cells after dbi (22.26 ± 2.97% at 72 h after dbi vs. 2.92 ± 0.88% in sham-operated animals). |
2014-07-15 |
2023-08-12 |
rat |
| Jianliang Chen, Xuesong Li, Jiandong Qiu, Hengxing You, Qingping Zhang, Guangyu Dong, You Zu. Kinetics of apoptosis and expression of apoptosis-related proteins in rat CA3 hippocampus cells after experimental diffuse brain injury. Cell biochemistry and biophysics. vol 67. issue 3. 2014-07-15. PMID:23559276. |
in conclusion, cell apoptosis and altered expressions of bcl-2, bax, and caspase-3 are present in the ca3 region of hippocampus after experimental dbi. |
2014-07-15 |
2023-08-12 |
rat |
| Praveen Kumar Kadeyala, Saritha Sannadi, Rajarami Reddy Gottipol. Alterations in apoptotic caspases and antioxidant enzymes in arsenic exposed rat brain regions: reversal effect of essential metals and a chelating agent. Environmental toxicology and pharmacology. vol 36. issue 3. 2014-07-15. PMID:24184500. |
the present study was designed to evaluate the protective effect of calcium, zinc or monoisoamyl dimercaptosuccinic acid (miadmsa), either individually or in combination on as induced oxidative stress and apoptosis in brain regions (cerebral cortex, hippocampus and cerebellum) of postnatal day (pnd) 21, 28 and 3 months old rats. |
2014-07-15 |
2023-08-12 |
rat |
| Jun Zhang, Kai-Fu Ke, Zhan Liu, Yi-Hua Qiu, Yu-Ping Pen. Th17 cell-mediated neuroinflammation is involved in neurodegeneration of aβ1-42-induced Alzheimer's disease model rats. PloS one. vol 8. issue 10. 2014-07-11. PMID:24124514. |
further, the immunofluorescent histochemistry on ad hippocampal sections with neun, rorγ, fas and fasl displayed that fas was principally expressed by neurons and fasl was predominantly expressed by th17 cells, and that neuronal apoptosis shown by tunel and neun double-labeled cells increased. |
2014-07-11 |
2023-08-12 |
rat |
| Wan-Xia Xiong, Guo-Xia Zhou, Bei Wang, Zhang-Gang Xue, Lu Wang, Hui-Chuan Sun, Sheng-Jin G. Impaired spatial learning and memory after sevoflurane-nitrous oxide anesthesia in aged rats is associated with down-regulated cAMP/CREB signaling. PloS one. vol 8. issue 11. 2014-07-11. PMID:24260214. |
besides these, the current study also found the dg neurogenesis significantly decreased as well as neuronal loss and neuronal apoptosis increased in the hippocampus of rats exposed to sev+n2o. |
2014-07-11 |
2023-08-12 |
rat |
| Svetlana Zonis, Vladimir A Ljubimov, Michael Mahgerefteh, Robert N Pechnick, Kolja Wawrowsky, Vera Chesnokov. p21Cip restrains hippocampal neurogenesis and protects neuronal progenitors from apoptosis during acute systemic inflammation. Hippocampus. vol 23. issue 12. 2014-07-09. PMID:23966332. |
p21cip restrains hippocampal neurogenesis and protects neuronal progenitors from apoptosis during acute systemic inflammation. |
2014-07-09 |
2023-08-12 |
mouse |
| Svetlana Zonis, Vladimir A Ljubimov, Michael Mahgerefteh, Robert N Pechnick, Kolja Wawrowsky, Vera Chesnokov. p21Cip restrains hippocampal neurogenesis and protects neuronal progenitors from apoptosis during acute systemic inflammation. Hippocampus. vol 23. issue 12. 2014-07-09. PMID:23966332. |
the current study suggests that p21 is induced in vivo in the hippocampus of wt mice in response to acute systemic inflammation caused by lps injections, restrains neuronal progenitor proliferation and protects these cells from inflammation-induced apoptosis. |
2014-07-09 |
2023-08-12 |
mouse |