| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yue He, Ailing Zhou, Wei Jian. Toll-like receptor 4-mediated signaling participates in apoptosis of hippocampal neurons. Neural regeneration research. vol 8. issue 29. 2014-09-10. PMID:25206585. |
these findings suggest that the tlr4-pi3k/akt-gsk3β signaling pathway may be involved in lipopolysaccharide-induced apoptosis of hippocampal neurons. |
2014-09-10 |
2023-08-13 |
Not clear |
| Yanjun Du, Ruolan Liu, Guojie Sun, Peiyan Meng, Jie Son. Pre-moxibustion and moxibustion prevent Alzheimer's disease. Neural regeneration research. vol 8. issue 30. 2014-09-10. PMID:25206602. |
results showed no evidence of apoptosis in hippocampal neurons, a significantly reduced apoptosis rate of neurons and improved learning and memory abilities were observed in the alzheimer's disease model. |
2014-09-10 |
2023-08-13 |
rat |
| Lijuan Xu, Shuling Zhang, Hongling Fan, Zhichao Zhong, Xi Li, Xiaoxiao Jin, Quanzhong Chan. ClC-3 chloride channel in hippocampal neuronal apoptosis. Neural regeneration research. vol 8. issue 32. 2014-09-10. PMID:25206625. |
clc-3 chloride channel in hippocampal neuronal apoptosis. |
2014-09-10 |
2023-08-13 |
rat |
| Lijuan Xu, Shuling Zhang, Hongling Fan, Zhichao Zhong, Xi Li, Xiaoxiao Jin, Quanzhong Chan. ClC-3 chloride channel in hippocampal neuronal apoptosis. Neural regeneration research. vol 8. issue 32. 2014-09-10. PMID:25206625. |
our findings indicate that the increased activities of the clc-3 chloride channel may be involved in hippocampal neuronal apoptosis induced by nitric oxide. |
2014-09-10 |
2023-08-13 |
rat |
| Shumin Zhao, Wei Kong, Shufeng Zhang, Meng Chen, Xiaoying Zheng, Xiangyu Kon. Pretreatment with scutellaria baicalensis stem-leaf total flavonoid prevents cerebral ischemia-reperfusion injury. Neural regeneration research. vol 8. issue 34. 2014-09-10. PMID:25206639. |
pretreatment with scutellaria baicalensis stem-leaf total flavonoid at any dose lowered the neurological deficit scores, reduced the infarct volume, prevented apoptosis in hippocampal cells, attenuated neuronal and blood-brain barrier damage and upregulated bcl-2 protein expression but inhibited bax protein expression. |
2014-09-10 |
2023-08-13 |
rat |
| Cuicui Yu, Junke Wan. Neuroprotective effect of penehyclidine hydrochloride on focal cerebral ischemia-reperfusion injury. Neural regeneration research. vol 8. issue 7. 2014-09-10. PMID:25206707. |
tetrazolium chloride, terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate-biotin nick end labeling and immunohistochemical staining showed that, penehyclidine hydrochloride pretreatment markedly attenuated neuronal histopathological changes in the cortex, hippocampus and striatum, reduced infarction size, increased the expression level of bcl-2, decreased the expression level of caspase-3, and inhibited neuronal apoptosis in rats with cerebral ischemia-reperfusion injury. |
2014-09-10 |
2023-08-13 |
rat |
| Hongliang Liu, Tijun Dai, Weitao Gu. Isoflurane-induced neuronal apoptosis in developing hippocampal neurons. Neural regeneration research. vol 8. issue 9. 2014-09-10. PMID:25206730. |
isoflurane-induced neuronal apoptosis in developing hippocampal neurons. |
2014-09-10 |
2023-08-13 |
rat |
| Hongliang Liu, Tijun Dai, Weitao Gu. Isoflurane-induced neuronal apoptosis in developing hippocampal neurons. Neural regeneration research. vol 8. issue 9. 2014-09-10. PMID:25206730. |
we hypothesized that the p2x7 receptor may be the target of isoflurane, so we investigated the roles of the p2x7 receptor and inositol triphosphate receptor in calcium overload and neuronal apoptosis induced by isoflurane in cultured embryonic rat hippocampal neurons. |
2014-09-10 |
2023-08-13 |
rat |
| Xiangyu Ji, Li'na Zhang, Ran Liu, Yingzhi Liu, Jianfang Song, He Dong, Yanfang Jia, Zangong Zho. Potential targets for protecting against hippocampal cell apoptosis after transient cerebral ischemia-reperfusion injury in aged rats. Neural regeneration research. vol 9. issue 11. 2014-09-10. PMID:25206771. |
potential targets for protecting against hippocampal cell apoptosis after transient cerebral ischemia-reperfusion injury in aged rats. |
2014-09-10 |
2023-08-13 |
rat |
| Xiangyu Ji, Li'na Zhang, Ran Liu, Yingzhi Liu, Jianfang Song, He Dong, Yanfang Jia, Zangong Zho. Potential targets for protecting against hippocampal cell apoptosis after transient cerebral ischemia-reperfusion injury in aged rats. Neural regeneration research. vol 9. issue 11. 2014-09-10. PMID:25206771. |
this study investigated the involvement of mitochondrial proteins in hippocampal cell apoptosis after transient cerebral ischemia-reperfusion injury in aged rats using a comparative proteomics strategy. |
2014-09-10 |
2023-08-13 |
rat |
| Xiangyu Ji, Li'na Zhang, Ran Liu, Yingzhi Liu, Jianfang Song, He Dong, Yanfang Jia, Zangong Zho. Potential targets for protecting against hippocampal cell apoptosis after transient cerebral ischemia-reperfusion injury in aged rats. Neural regeneration research. vol 9. issue 11. 2014-09-10. PMID:25206771. |
our experimental results show that the aged rat brain is sensitive to ischemia-reperfusion injury and that transient ischemia led to cell apoptosis in the hippocampus and changes in memory and cognition of aged rats. |
2014-09-10 |
2023-08-13 |
rat |
| Xiqing Chai, Weina Kong, Lingyun Liu, Wenguo Yu, Zhenqing Zhang, Yimin Su. A viral vector expressing hypoxia-inducible factor 1 alpha inhibits hippocampal neuronal apoptosis. Neural regeneration research. vol 9. issue 11. 2014-09-10. PMID:25206774. |
a viral vector expressing hypoxia-inducible factor 1 alpha inhibits hippocampal neuronal apoptosis. |
2014-09-10 |
2023-08-13 |
human |
| Xiqing Chai, Weina Kong, Lingyun Liu, Wenguo Yu, Zhenqing Zhang, Yimin Su. A viral vector expressing hypoxia-inducible factor 1 alpha inhibits hippocampal neuronal apoptosis. Neural regeneration research. vol 9. issue 11. 2014-09-10. PMID:25206774. |
in this study, we constructed a recombinant adeno-associated virus (raav) vector expressing the human hif-1α gene (raav-hif-1α), and tested the assumption that raav-hif-1α represses hippocampal neuronal apoptosis induced by amyloid-beta protein. |
2014-09-10 |
2023-08-13 |
human |
| Xiqing Chai, Weina Kong, Lingyun Liu, Wenguo Yu, Zhenqing Zhang, Yimin Su. A viral vector expressing hypoxia-inducible factor 1 alpha inhibits hippocampal neuronal apoptosis. Neural regeneration research. vol 9. issue 11. 2014-09-10. PMID:25206774. |
our results confirmed that raav-hif-1α significantly reduces apoptosis induced by amyloid-beta protein in primary cultured hippocampal neurons. |
2014-09-10 |
2023-08-13 |
human |
| Xiqing Chai, Weina Kong, Lingyun Liu, Wenguo Yu, Zhenqing Zhang, Yimin Su. A viral vector expressing hypoxia-inducible factor 1 alpha inhibits hippocampal neuronal apoptosis. Neural regeneration research. vol 9. issue 11. 2014-09-10. PMID:25206774. |
single raav-hif-1α administration resulted in decreased apoptosis of hippocampal neurons in an alzheimer's disease rat model established by intracerebroventricular injection of aggregated amyloid-beta protein (25-35). |
2014-09-10 |
2023-08-13 |
human |
| Xiqing Chai, Weina Kong, Lingyun Liu, Wenguo Yu, Zhenqing Zhang, Yimin Su. A viral vector expressing hypoxia-inducible factor 1 alpha inhibits hippocampal neuronal apoptosis. Neural regeneration research. vol 9. issue 11. 2014-09-10. PMID:25206774. |
our in vitro and in vivo findings demonstrate that hif-1 has potential for attenuating hippocampal neuronal apoptosis induced by amyloid-beta protein, and provides experimental support for treatment of neurodegenerative diseases using gene therapy. |
2014-09-10 |
2023-08-13 |
human |
| Xiaorong Hou, Rongjun Zhang, Hang Lv, Xinghui Cai, Guangchuan Xie, Xiaoge Son. Acupuncture at Baihui and Dazhui reduces brain cell apoptosis in heroin readdicts. Neural regeneration research. vol 9. issue 2. 2014-09-10. PMID:25206797. |
in this study, cell apoptosis was observed in the hippocampus and frontal lobe of heroin readdicted rats by electron microscopy. |
2014-09-10 |
2023-08-13 |
rat |
| Yaning Zhao, Jianmin Li, Qiqun Tang, Pan Zhang, Liwei Jing, Changxiang Chen, Shuxing L. Regulation of extracellular signal-regulated kinase 1/2 influences hippocampal neuronal survival in a rat model of diabetic cerebral ischemia. Neural regeneration research. vol 9. issue 7. 2014-09-10. PMID:25206883. |
these findings demonstrate that inhibition of extracellular signal-regulated kinase 1/2 activity aggravated neuronal loss in the hippocampus in a diabetic rat after cerebral ischemia/reperfusion, further decreased dna repairing ability and accelerated apoptosis in hippocampal neurons. |
2014-09-10 |
2023-08-13 |
rat |
| Juan Liu, Jing He, Liang Huang, Ling Dou, Shuang Wu, Qionglan Yua. Neuroprotective effects of ginsenoside Rb1 on hippocampal neuronal injury and neurite outgrowth. Neural regeneration research. vol 9. issue 9. 2014-09-10. PMID:25206916. |
additionally, cultured hippocampal neurons were exposed to amyloid beta (25-35) for 30 minutes; ginsenoside rb1 prevented apoptosis induced by amyloid beta (25-35), and this effect was blocked by api-2 and pd98059. |
2014-09-10 |
2023-08-13 |
Not clear |
| Debora Cutuli, Paola De Bartolo, Paola Caporali, Daniela Laricchiuta, Francesca Foti, Maurizio Ronci, Claudia Rossi, Cristina Neri, Gianfranco Spalletta, Carlo Caltagirone, Stefano Farioli-Vecchioli, Laura Petrosin. n-3 polyunsaturated fatty acids supplementation enhances hippocampal functionality in aged mice. Frontiers in aging neuroscience. vol 6. 2014-09-09. PMID:25202271. |
in fact, n-3 pufa supplementation increased hippocampal neurogenesis and dendritic arborization of newborn neurons, volume, neuronal density and microglial cell number, while it decreased apoptosis, astrocytosis and lipofuscin accumulation in the hippocampus. |
2014-09-09 |
2023-08-13 |
mouse |