| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mia Kim, Ki-Ho Cho, Mal-Soon Shin, Jae-Min Lee, Han-Sam Cho, Chang-Ju Kim, Dong-Hoon Shin, Hyeon Jeong Yan. Berberine prevents nigrostriatal dopaminergic neuronal loss and suppresses hippocampal apoptosis in mice with Parkinson's disease. International journal of molecular medicine. vol 33. issue 4. 2014-10-21. PMID:24535622. |
treatment with berberine also improved short-term memory by inhibiting apoptosis in the hippocampus. |
2014-10-21 |
2023-08-12 |
mouse |
| Yang-Yang Wu, Wang-Yang Wu, Hui-Ling Gong, Wei-Zu Li, Yan-Yan Yi. Astragalosides attenuate learning and memory impairment in rats following ischemia‑reperfusion injury. Molecular medicine reports. vol 9. issue 4. 2014-10-21. PMID:24567111. |
a histological examination and hoechst 33258 staining was used to observe the neuronal changes and apoptosis in the hippocampus. |
2014-10-21 |
2023-08-12 |
rat |
| Yasaman Razavi, Shabnam Zeighamy Alamdary, Seyedeh-Najmeh Katebi, Fariba Khodagholi, Abbas Haghparas. Morphine-induced apoptosis in the ventral tegmental area and hippocampus after the development but not extinction of reward-related behaviors in rats. Cellular and molecular neurobiology. vol 34. issue 2. 2014-10-16. PMID:24281942. |
morphine-induced apoptosis in the ventral tegmental area and hippocampus after the development but not extinction of reward-related behaviors in rats. |
2014-10-16 |
2023-08-12 |
rat |
| Yun Peng, Bo Jiang, Huiling Wu, Ruchun Dai, Liming Ta. Effects of genistein on neuronal apoptosis, and expression of Bcl-2 and Bax proteins in the hippocampus of ovariectomized rats. Neural regeneration research. vol 7. issue 36. 2014-10-15. PMID:25317139. |
effects of genistein on neuronal apoptosis, and expression of bcl-2 and bax proteins in the hippocampus of ovariectomized rats. |
2014-10-15 |
2023-08-13 |
rat |
| Yun Peng, Bo Jiang, Huiling Wu, Ruchun Dai, Liming Ta. Effects of genistein on neuronal apoptosis, and expression of Bcl-2 and Bax proteins in the hippocampus of ovariectomized rats. Neural regeneration research. vol 7. issue 36. 2014-10-15. PMID:25317139. |
at 15 weeks after ovariectomy, the expression of bcl-2 in the hippocampus of rats decreased and bax expression increased, with an obvious upregulation of apoptosis. |
2014-10-15 |
2023-08-13 |
rat |
| Yun Peng, Bo Jiang, Huiling Wu, Ruchun Dai, Liming Ta. Effects of genistein on neuronal apoptosis, and expression of Bcl-2 and Bax proteins in the hippocampus of ovariectomized rats. Neural regeneration research. vol 7. issue 36. 2014-10-15. PMID:25317139. |
however, intraperitoneal injection of genistein or 17β-estradiol for 15 consecutive weeks from the second day after operation upregulated bcl-2 protein expression, downregulated bax protein expression, and attenuated hippocampal neuron apoptosis. |
2014-10-15 |
2023-08-13 |
rat |
| Yun Peng, Bo Jiang, Huiling Wu, Ruchun Dai, Liming Ta. Effects of genistein on neuronal apoptosis, and expression of Bcl-2 and Bax proteins in the hippocampus of ovariectomized rats. Neural regeneration research. vol 7. issue 36. 2014-10-15. PMID:25317139. |
our experimental findings indicate that long-term intervention with genistein can lead to a decrease in apoptosis in hippocampal neurons following ovariectomy, upregulate the expression of bcl-2, and downregulate the expression of bax. |
2014-10-15 |
2023-08-13 |
rat |
| Alexander J Engelmann, Mark B Aparicio, Airee Kim, Jeffery C Sobieraj, Clara J Yuan, Yanabel Grant, Chitra D Mandya. Chronic wheel running reduces maladaptive patterns of methamphetamine intake: regulation by attenuation of methamphetamine-induced neuronal nitric oxide synthase. Brain structure & function. vol 219. issue 2. 2014-10-14. PMID:23443965. |
wr-induced beneficial effects on methamphetamine self-administration were not attributable to neuroplasticity effects in the hippocampus and medial prefrontal cortex, but were attributable to wr-induced inhibition of methamphetamine-induced increases in the number of neuronal nitric oxide synthase expressing neurons and apoptosis in the nucleus accumbens shell. |
2014-10-14 |
2023-08-12 |
rat |
| Xiaobo Lu, Cuihong Jin, Jinghua Yang, Qiufang Liu, Shengwen Wu, Dandan Li, Yangyang Guan, Yuan Ca. Prenatal and lactational lead exposure enhanced oxidative stress and altered apoptosis status in offspring rats' hippocampus. Biological trace element research. vol 151. issue 1. 2014-10-10. PMID:23086308. |
prenatal and lactational lead exposure enhanced oxidative stress and altered apoptosis status in offspring rats' hippocampus. |
2014-10-10 |
2023-08-12 |
rat |
| Xiaobo Lu, Cuihong Jin, Jinghua Yang, Qiufang Liu, Shengwen Wu, Dandan Li, Yangyang Guan, Yuan Ca. Prenatal and lactational lead exposure enhanced oxidative stress and altered apoptosis status in offspring rats' hippocampus. Biological trace element research. vol 151. issue 1. 2014-10-10. PMID:23086308. |
to better understand the adverse effect on the developing central nervous system (cns) after lead exposure during pregnancy and lactation, the indexes of oxidative stress, apoptosis status, and bax and bcl-2 expression of offspring rats' hippocampus were determined. |
2014-10-10 |
2023-08-12 |
rat |
| Xiao-Min Li, Mai-Tao Zhou, Xing-Ming Wang, Mu-Huo Ji, Zhi-Qiang Zhou, Jian-Jun Yan. Resveratrol pretreatment attenuates the isoflurane-induced cognitive impairment through its anti-inflammation and -apoptosis actions in aged mice. Journal of molecular neuroscience : MN. vol 52. issue 2. 2014-10-06. PMID:24126892. |
we therefore aimed to investigate the effects of resveratrol on the isoflurane-induced cognitive impairments and the associated hippocampal inflammation responses and neuronal apoptosis in the aged mice. |
2014-10-06 |
2023-08-12 |
mouse |
| Mia Kim, Mal Soon Shin, Jae Min Lee, Han Sam Cho, Chang Ju Kim, Young Joon Kim, Hey Ran Choi, Jung Won Jeo. Inhibitory Effects of Isoquinoline Alkaloid Berberine on Ischemia-Induced Apoptosis via Activation of Phosphoinositide 3-Kinase/Protein Kinase B Signaling Pathway. International neurourology journal. vol 18. issue 3. 2014-10-03. PMID:25279238. |
in the present study, we investigated the effects of berberine on global ischemia-induced apoptosis, and focused on the phosphoinositide 3-kinase (pi3k)/protein kinase b (akt) signaling pathway in the hippocampus using gerbils. |
2014-10-03 |
2023-08-13 |
Not clear |
| D Jia, L-J Heng, R-H Yang, G-D Ga. Fish oil improves learning impairments of diabetic rats by blocking PI3K/AKT/nuclear factor-κB-mediated inflammatory pathways. Neuroscience. vol 258. 2014-09-29. PMID:24252320. |
the present study investigated the effects of fish oil supplementation on the lipid peroxidation, inflammation and neuron apoptosis in the hippocampus of streptozotocin (stz)-induced diabetes rats. |
2014-09-29 |
2023-08-12 |
rat |
| D Jia, L-J Heng, R-H Yang, G-D Ga. Fish oil improves learning impairments of diabetic rats by blocking PI3K/AKT/nuclear factor-κB-mediated inflammatory pathways. Neuroscience. vol 258. 2014-09-29. PMID:24252320. |
stz-induced diabetes impaired spatial learning and memory of rats, which was associated with the inflammation, oxidative stress and apoptosis of hippocampal neurons. |
2014-09-29 |
2023-08-12 |
rat |
| Yansong Wang, Wei Wang, Dongguo Li, Mi Li, Peipei Wang, Jian Wen, Min Liang, Bo Su, Yanling Yi. IGF-1 alleviates NMDA-induced excitotoxicity in cultured hippocampal neurons against autophagy via the NR2B/PI3K-AKT-mTOR pathway. Journal of cellular physiology. vol 229. issue 11. 2014-09-25. PMID:24604717. |
together, these data suggest that nmda induces the autophagy, followed by apoptosis in cultured hippocampal neurons, and that igf-1 can block this effect via inhibition of nr2b receptors and activation of the pi3k-akt-mtor pathway. |
2014-09-25 |
2023-08-12 |
Not clear |
| Masatoshi Kakizaki, Hiromi Kashiwazaki, Rihito Watanab. Mutant murine hepatitis virus-induced apoptosis in the hippocampus. Japanese journal of infectious diseases. vol 67. issue 1. 2014-09-15. PMID:24451095. |
mutant murine hepatitis virus-induced apoptosis in the hippocampus. |
2014-09-15 |
2023-08-12 |
mouse |
| Masatoshi Kakizaki, Hiromi Kashiwazaki, Rihito Watanab. Mutant murine hepatitis virus-induced apoptosis in the hippocampus. Japanese journal of infectious diseases. vol 67. issue 1. 2014-09-15. PMID:24451095. |
in contrast, in cl-2 infection, 10-20% of the infected mice exhibited apoptosis in the hippocampus, which was primarily observed in the ca1 subregion. |
2014-09-15 |
2023-08-12 |
mouse |
| Mehmet Bülent Ozdemir, Cagdas Erdogan, Katsunori Iwasaki, Takuya Watanabe, Shin Ishikane, Michihiro Fujiwar. Injection of specific amyloid-beta oligomers (beta₁₋₄₀:beta₁₋₄₂ = 10:1) into rat medial septum impairs memory retention without inducing hippocampal apoptosis. Neurological research. vol 35. issue 8. 2014-09-12. PMID:23622689. |
injection of specific amyloid-beta oligomers (beta₁₋₄₀:beta₁₋₄₂ = 10:1) into rat medial septum impairs memory retention without inducing hippocampal apoptosis. |
2014-09-12 |
2023-08-12 |
rat |
| N Uysal, M Kiray, A R Sisman, B Baykara, I Aksu, A Dayi, C Gencoglu, M Evren, E Buyuk, F Cetin, O Acikgo. Effects of exercise and poor indoor air quality on learning, memory and blood IGF-1 in adolescent mice. Biotechnic & histochemistry : official publication of the Biological Stain Commission. vol 89. issue 2. 2014-09-12. PMID:24050191. |
poor air quality increased apoptosis in the hippocampus and pfc. |
2014-09-12 |
2023-08-12 |
mouse |
| Young Hoon Kim, Yun-Hee Sung, Hee-Hyuk Lee, Il-Gyu Ko, Sung-Eun Kim, Mal-Soon Shin, Bo-Kyun Ki. Postnatal treadmill exercise alleviates short-term memory impairment by enhancing cell proliferation and suppressing apoptosis in the hippocampus of rat pups born to diabetic rats. Journal of exercise rehabilitation. vol 10. issue 4. 2014-09-11. PMID:25210695. |
postnatal treadmill exercise alleviates short-term memory impairment by enhancing cell proliferation and suppressing apoptosis in the hippocampus of rat pups born to diabetic rats. |
2014-09-11 |
2023-08-13 |
rat |