| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cheng Chen, Yun Wang, Juan Zhang, Lian Ma, Jiang Gu, Guyu H. Contribution of neural cell death to depressive phenotypes of streptozotocin-induced diabetic mice. Disease models & mechanisms. vol 7. issue 6. 2015-01-12. PMID:24764190. |
immunohistological studies showed markedly increased tunel-positive cells in the frontal cortex and hippocampus of the comorbid mice, indicating apoptosis. |
2015-01-12 |
2023-08-13 |
mouse |
| Clayton W Winkler, Katherine G Taylor, Karin E Peterso. Location is everything: let-7b microRNA and TLR7 signaling results in a painful TRP. Science signaling. vol 7. issue 327. 2015-01-10. PMID:24866018. |
found that let-7b stimulation of cortical and hippocampal neurons led to neuronal apoptosis, whereas park et al. |
2015-01-10 |
2023-08-13 |
Not clear |
| T Kreisel, M G Frank, T Licht, R Reshef, O Ben-Menachem-Zidon, M V Baratta, S F Maier, R Yirmiy. Dynamic microglial alterations underlie stress-induced depressive-like behavior and suppressed neurogenesis. Molecular psychiatry. vol 19. issue 6. 2015-01-09. PMID:24342992. |
we report that following an initial period (2-3 days) of stress-induced microglial proliferation and activation, some microglia underwent apoptosis, leading to reductions in their numbers within the hippocampus, but not in other brain regions, following 5 weeks of cus exposure. |
2015-01-09 |
2023-08-12 |
mouse |
| Yue Zhang, Wei Liu, Yi Zhou, Chunling Ma, Shujin Li, Bin Con. Endoplasmic reticulum stress is involved in restraint stress-induced hippocampal apoptosis and cognitive impairments in rats. Physiology & behavior. vol 131. 2015-01-07. PMID:24732417. |
endoplasmic reticulum stress is involved in restraint stress-induced hippocampal apoptosis and cognitive impairments in rats. |
2015-01-07 |
2023-08-13 |
rat |
| Yue Zhang, Wei Liu, Yi Zhou, Chunling Ma, Shujin Li, Bin Con. Endoplasmic reticulum stress is involved in restraint stress-induced hippocampal apoptosis and cognitive impairments in rats. Physiology & behavior. vol 131. 2015-01-07. PMID:24732417. |
the present study investigated the involvement of ers in restraint stress (rs)-induced hippocampal apoptosis and cognitive impairments. |
2015-01-07 |
2023-08-13 |
rat |
| Yue Zhang, Wei Liu, Yi Zhou, Chunling Ma, Shujin Li, Bin Con. Endoplasmic reticulum stress is involved in restraint stress-induced hippocampal apoptosis and cognitive impairments in rats. Physiology & behavior. vol 131. 2015-01-07. PMID:24732417. |
furthermore, in the three possible signaling pathways of ers-induced apoptosis, the protein and mrna levels of c/ebp homologous protein (chop) were significantly up-regulated, and caspase-12 was activated and cleaved, which suggested that these two pathways crucially contributed to hippocampal cell death. |
2015-01-07 |
2023-08-13 |
rat |
| Yue Zhang, Wei Liu, Yi Zhou, Chunling Ma, Shujin Li, Bin Con. Endoplasmic reticulum stress is involved in restraint stress-induced hippocampal apoptosis and cognitive impairments in rats. Physiology & behavior. vol 131. 2015-01-07. PMID:24732417. |
however, we found no changes in protein levels of phosphorylated jnk, implying that the jnk pathway was not the primary pathway involved in hippocampal apoptosis. |
2015-01-07 |
2023-08-13 |
rat |
| Tae-Beom Seo, Tae-Woon Kim, Mal-Soon Shin, Eun-Sang Ji, Han-Sam Cho, Jae-Min Lee, Tae-Wook Kim, Chang-Ju Ki. Aerobic exercise alleviates ischemia-induced memory impairment by enhancing cell proliferation and suppressing neuronal apoptosis in hippocampus. International neurourology journal. vol 18. issue 4. 2015-01-06. PMID:25562035. |
aerobic exercise alleviates ischemia-induced memory impairment by enhancing cell proliferation and suppressing neuronal apoptosis in hippocampus. |
2015-01-06 |
2023-08-13 |
Not clear |
| Tae-Beom Seo, Tae-Woon Kim, Mal-Soon Shin, Eun-Sang Ji, Han-Sam Cho, Jae-Min Lee, Tae-Wook Kim, Chang-Ju Ki. Aerobic exercise alleviates ischemia-induced memory impairment by enhancing cell proliferation and suppressing neuronal apoptosis in hippocampus. International neurourology journal. vol 18. issue 4. 2015-01-06. PMID:25562035. |
in the present study, we investigated the effects of treadmill exercise on memory function and its relation to cell proliferation and apoptosis in the hippocampus, following transient global ischemia in gerbils. |
2015-01-06 |
2023-08-13 |
Not clear |
| Yu-Jing Liu, Yu F. [Progress of experimental research on treating Alzheimer's disease by acupuncture]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine. vol 34. issue 3. 2015-01-05. PMID:24758091. |
senile dementia rats' cognitive capabilities and memory could be improved by reduction of beta-amyloid protein, attenuation of excessive phosphorylation of tau protein, regulation of center neurotransmitter dysmetabolism, oxidation of anti-free radicals, reduction of neuron apoptosis in the cortex and the hippocampus, inhibition of glial cells' differentiation, adjustment of g protein signaling transduction, and improvement of the mitochondrial dysfunction, thus providing experimental evidence for treating ad by acupuncture. |
2015-01-05 |
2023-08-13 |
rat |
| Xiao-Ping Yang, Tao-Yan Liu, Xiao-Yan Qin, Long-Chuan Y. Potential protection of 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside against staurosporine-induced toxicity on cultured rat hippocampus neurons. Neuroscience letters. vol 576. 2015-01-05. PMID:24887581. |
the results showed that administration of 200μm of thsg significantly protected against 0.3μm of sts-induced apoptosis in cultured rat hippocampal neurons tested by methyl thiazolyl tetrazolium (mtt) and terminal deoxynucleotidyl transferase-mediated dutp nick-end labeling (tunel) assays. |
2015-01-05 |
2023-08-13 |
rat |
| Jon G Holler, Christian T Brandt, Stephen L Leib, Ian J Rowland, Christian Østergaar. Increase in hippocampal water diffusion and volume during experimental pneumococcal meningitis is aggravated by bacteremia. BMC infectious diseases. vol 14. 2014-12-30. PMID:24886045. |
the hippocampus undergoes apoptosis in experimental pneumococcal meningitis leading to neurofunctional deficits in learning and memory function. |
2014-12-30 |
2023-08-13 |
Not clear |
| Jon G Holler, Christian T Brandt, Stephen L Leib, Ian J Rowland, Christian Østergaar. Increase in hippocampal water diffusion and volume during experimental pneumococcal meningitis is aggravated by bacteremia. BMC infectious diseases. vol 14. 2014-12-30. PMID:24886045. |
the aim of the present study was 1) to investigate hippocampal apparent diffusion coefficient (adc) and volume with mri during the course of experimental pneumococcal meningitis, 2) to explore the influence of accompanying bacteremia on hippocampal water distribution and volume, 3) and to correlate these findings to the extent of apoptosis in the hippocampus. |
2014-12-30 |
2023-08-13 |
Not clear |
| Chih-Yang Huang, Wei-Wen Kuo, Hung-En Liao, Yueh-Min Lin, Chia-Hua Kuo, Fuu-Jen Tsai, Chang-Hai Tsai, Jia-Long Chen, Jing-Ying Li. Lumbrokinase attenuates side-stream-smoke-induced apoptosis and autophagy in young hamster hippocampus: correlated with eNOS induction and NFκB/iNOS/COX-2 signaling suppression. Chemical research in toxicology. vol 26. issue 5. 2014-12-22. PMID:23682761. |
lumbrokinase attenuates side-stream-smoke-induced apoptosis and autophagy in young hamster hippocampus: correlated with enos induction and nfκb/inos/cox-2 signaling suppression. |
2014-12-22 |
2023-08-12 |
Not clear |
| Chih-Yang Huang, Wei-Wen Kuo, Hung-En Liao, Yueh-Min Lin, Chia-Hua Kuo, Fuu-Jen Tsai, Chang-Hai Tsai, Jia-Long Chen, Jing-Ying Li. Lumbrokinase attenuates side-stream-smoke-induced apoptosis and autophagy in young hamster hippocampus: correlated with eNOS induction and NFκB/iNOS/COX-2 signaling suppression. Chemical research in toxicology. vol 26. issue 5. 2014-12-22. PMID:23682761. |
this study evaluated the influence of side stream smoke (sss) exposure on hippocampal apoptosis and of the lumbrokinase (lk) effects on sss induced apoptosis in young hamster hippocampus. |
2014-12-22 |
2023-08-12 |
Not clear |
| Chih-Yang Huang, Wei-Wen Kuo, Hung-En Liao, Yueh-Min Lin, Chia-Hua Kuo, Fuu-Jen Tsai, Chang-Hai Tsai, Jia-Long Chen, Jing-Ying Li. Lumbrokinase attenuates side-stream-smoke-induced apoptosis and autophagy in young hamster hippocampus: correlated with eNOS induction and NFκB/iNOS/COX-2 signaling suppression. Chemical research in toxicology. vol 26. issue 5. 2014-12-22. PMID:23682761. |
we found that the detrimental effects of sss on the hippocampus are truly mediated by cell apoptosis and autophagy. |
2014-12-22 |
2023-08-12 |
Not clear |
| Chih-Yang Huang, Wei-Wen Kuo, Hung-En Liao, Yueh-Min Lin, Chia-Hua Kuo, Fuu-Jen Tsai, Chang-Hai Tsai, Jia-Long Chen, Jing-Ying Li. Lumbrokinase attenuates side-stream-smoke-induced apoptosis and autophagy in young hamster hippocampus: correlated with eNOS induction and NFκB/iNOS/COX-2 signaling suppression. Chemical research in toxicology. vol 26. issue 5. 2014-12-22. PMID:23682761. |
however, lk reduced the hippocampus apoptosis and autophagy related injuries induced by sss in a widespread manner. |
2014-12-22 |
2023-08-12 |
Not clear |
| Chih-Yang Huang, Wei-Wen Kuo, Hung-En Liao, Yueh-Min Lin, Chia-Hua Kuo, Fuu-Jen Tsai, Chang-Hai Tsai, Jia-Long Chen, Jing-Ying Li. Lumbrokinase attenuates side-stream-smoke-induced apoptosis and autophagy in young hamster hippocampus: correlated with eNOS induction and NFκB/iNOS/COX-2 signaling suppression. Chemical research in toxicology. vol 26. issue 5. 2014-12-22. PMID:23682761. |
we suggest that lk presents protective effects on hippocampus apoptosis and has therapeutic potential against abnormal hippocampal function. |
2014-12-22 |
2023-08-12 |
Not clear |
| Shu Yang, Qihai Gong, Qin Wu, Fei Li, Yuanfu Lu, Jingshan Sh. Alkaloids enriched extract from Dendrobium nobile Lindl. attenuates tau protein hyperphosphorylation and apoptosis induced by lipopolysaccharide in rat brain. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 21. issue 5. 2014-12-15. PMID:24268296. |
the present study demonstrated that ednla attenuates lps-induced hyperphosphorylation of tau protein in rat's hippocampus and protects against lps-induced apoptosis in rat brain. |
2014-12-15 |
2023-08-12 |
rat |
| Rasoul Ghasemi, Asadollah Zarifkar, Karim Rastegar, Nader Maghsoudi, Maryam Moosav. Repeated intra-hippocampal injection of beta-amyloid 25–35 induces a reproducible impairment of learning and memory: considering caspase-3 and MAPKs activity. European journal of pharmacology. vol 726. 2014-12-15. PMID:24418687. |
hippocampal western blot analysis revealed that behavioral impairment is in parallel with greater apoptosis and mapks activation. |
2014-12-15 |
2023-08-12 |
rat |