| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhen Sun, Jin-Tai Yu, Teng Jiang, Meng-Meng Li, Lin Tan, Qun Zhang, Lan Ta. Genome-wide microRNA profiling of rat hippocampus after status epilepticus induced by amygdala stimulation identifies modulators of neuronal apoptosis. PloS one. vol 8. issue 10. 2015-02-23. PMID:24205215. |
genome-wide microrna profiling of rat hippocampus after status epilepticus induced by amygdala stimulation identifies modulators of neuronal apoptosis. |
2015-02-23 |
2023-08-12 |
rat |
| Zhen Sun, Jin-Tai Yu, Teng Jiang, Meng-Meng Li, Lin Tan, Qun Zhang, Lan Ta. Genome-wide microRNA profiling of rat hippocampus after status epilepticus induced by amygdala stimulation identifies modulators of neuronal apoptosis. PloS one. vol 8. issue 10. 2015-02-23. PMID:24205215. |
meanwhile, neuronal survival and apoptosis in the hippocampus after se were evaluated by nissl staining and terminal deoxynucleotidyl transferase-mediated dutp end-labeling assay. |
2015-02-23 |
2023-08-12 |
rat |
| M Kiray, A R Sisman, U M Camsari, M Evren, A Dayi, B Baykara, I Aksu, M Ates, Nazan Uysa. Effects of carbon dioxide exposure on early brain development in rats. Biotechnic & histochemistry : official publication of the Biological Stain Commission. vol 89. issue 5. 2015-02-23. PMID:24476563. |
in addition, apoptosis was increased, while cell numbers were decreased in the ca1 regions of hippocampus and pfc after 0.3% co2 air exposure in adolescent rats. |
2015-02-23 |
2023-08-12 |
rat |
| Retraction notice to ‘‘The effect of maternal infection on cognitive development and hippocampus neuronal apoptosis, proliferation and differentiation in the neonatal rats’’ [Neuroscience 246 (2013) 422–434. Neuroscience. vol 254. 2015-02-23. PMID:24527492. |
retraction notice to ‘‘the effect of maternal infection on cognitive development and hippocampus neuronal apoptosis, proliferation and differentiation in the neonatal rats’’ [neuroscience 246 (2013) 422–434. |
2015-02-23 |
2023-08-12 |
Not clear |
| Jinying Wang, Peng Wang, Shuhong Li, Shilei Wang, Yu Li, Nan Liang, Min Wan. Mdivi-1 prevents apoptosis induced by ischemia-reperfusion injury in primary hippocampal cells via inhibition of reactive oxygen species-activated mitochondrial pathway. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. vol 23. issue 6. 2015-02-23. PMID:24774441. |
mdivi-1 prevents apoptosis induced by ischemia-reperfusion injury in primary hippocampal cells via inhibition of reactive oxygen species-activated mitochondrial pathway. |
2015-02-23 |
2023-08-13 |
rat |
| Goksin Nilufer Yonguc, Yavuz Dodurga, Esat Adiguzel, Gulsah Gundogdu, Vural Kucukatay, Seda Ozbal, Ismail Yilmaz, Ulker Cankurt, Yusuf Yilmaz, Ilgaz Akdoga. Grape seed extract has superior beneficial effects than vitamin E on oxidative stress and apoptosis in the hippocampus of streptozotocin induced diabetic rats. Gene. vol 555. issue 2. 2015-02-17. PMID:25445279. |
grape seed extract has superior beneficial effects than vitamin e on oxidative stress and apoptosis in the hippocampus of streptozotocin induced diabetic rats. |
2015-02-17 |
2023-08-13 |
rat |
| Goksin Nilufer Yonguc, Yavuz Dodurga, Esat Adiguzel, Gulsah Gundogdu, Vural Kucukatay, Seda Ozbal, Ismail Yilmaz, Ulker Cankurt, Yusuf Yilmaz, Ilgaz Akdoga. Grape seed extract has superior beneficial effects than vitamin E on oxidative stress and apoptosis in the hippocampus of streptozotocin induced diabetic rats. Gene. vol 555. issue 2. 2015-02-17. PMID:25445279. |
we aimed to investigate the effects of grape seed extract (gse) and vitamin e (vit e) on oxidative stress and apoptosis in the hippocampus of streptozotocin-induced diabetic rats. |
2015-02-17 |
2023-08-13 |
rat |
| Goksin Nilufer Yonguc, Yavuz Dodurga, Esat Adiguzel, Gulsah Gundogdu, Vural Kucukatay, Seda Ozbal, Ismail Yilmaz, Ulker Cankurt, Yusuf Yilmaz, Ilgaz Akdoga. Grape seed extract has superior beneficial effects than vitamin E on oxidative stress and apoptosis in the hippocampus of streptozotocin induced diabetic rats. Gene. vol 555. issue 2. 2015-02-17. PMID:25445279. |
in conclusion, gse (more prominently) and vitamin e decreased oxidative stress and neuronal apoptosis occurring in the hippocampus of diabetic rats. |
2015-02-17 |
2023-08-13 |
rat |
| Maryam Moosavi, Amir Hossein Zarifkar, Yaghoub Farbood, Mahin Dianat, Alireza Sarkaki, Rasoul Ghasem. Agmatine protects against intracerebroventricular streptozotocin-induced water maze memory deficit, hippocampal apoptosis and Akt/GSK3β signaling disruption. European journal of pharmacology. vol 736. 2015-02-13. PMID:24769303. |
agmatine protects against intracerebroventricular streptozotocin-induced water maze memory deficit, hippocampal apoptosis and akt/gsk3β signaling disruption. |
2015-02-13 |
2023-08-13 |
rat |
| Maryam Moosavi, Amir Hossein Zarifkar, Yaghoub Farbood, Mahin Dianat, Alireza Sarkaki, Rasoul Ghasem. Agmatine protects against intracerebroventricular streptozotocin-induced water maze memory deficit, hippocampal apoptosis and Akt/GSK3β signaling disruption. European journal of pharmacology. vol 736. 2015-02-13. PMID:24769303. |
after complement of behavioral studies the hippocampi was isolated and the amounts of hippocampal cleaved caspase-3 (the landmark of apoptosis), bax/bcl-2 ratio, total and phosphorylated forms of gsk-3β and akt were analyzed by western blot. |
2015-02-13 |
2023-08-13 |
rat |
| Maryam Moosavi, Amir Hossein Zarifkar, Yaghoub Farbood, Mahin Dianat, Alireza Sarkaki, Rasoul Ghasem. Agmatine protects against intracerebroventricular streptozotocin-induced water maze memory deficit, hippocampal apoptosis and Akt/GSK3β signaling disruption. European journal of pharmacology. vol 736. 2015-02-13. PMID:24769303. |
this study disclosed that agmatine treatment averts not only stz-induced memory deterioration but also hippocampal apoptosis and akt/gsk-3β signaling disruption. |
2015-02-13 |
2023-08-13 |
rat |
| Xue-Qin Hou, Dian-Wei Wu, Chun-Xia Zhang, Rong Yan, Cong Yang, Cui-Ping Rong, Lei Zhang, Xiang Chang, Ru-Yu Su, Shi-Jie Zhang, Wen-Qing He, Zhao Qu, Shi Li, Zi-Ren Su, Yun-Bo Chen, Qi Wang, Shu-Huan Fan. Bushen‑Yizhi formula ameliorates cognition deficits and attenuates oxidative stress‑related neuronal apoptosis in scopolamine‑induced senescence in mice. International journal of molecular medicine. vol 34. issue 2. 2015-02-12. PMID:24919922. |
the present study aimed to investigate the effects of bsyz on learning and memory abilities, as well as oxidative stress and neuronal apoptosis in the hippocampus of scopolamine (scop)‑induced senescence in mice, in order to reveal whether bsyz is a potential therapeutic agent for alzheimer's disease (ad). |
2015-02-12 |
2023-08-13 |
mouse |
| Xue-Qin Hou, Dian-Wei Wu, Chun-Xia Zhang, Rong Yan, Cong Yang, Cui-Ping Rong, Lei Zhang, Xiang Chang, Ru-Yu Su, Shi-Jie Zhang, Wen-Qing He, Zhao Qu, Shi Li, Zi-Ren Su, Yun-Bo Chen, Qi Wang, Shu-Huan Fan. Bushen‑Yizhi formula ameliorates cognition deficits and attenuates oxidative stress‑related neuronal apoptosis in scopolamine‑induced senescence in mice. International journal of molecular medicine. vol 34. issue 2. 2015-02-12. PMID:24919922. |
moreover, the neural apoptosis in the hippocampus of scop‑treated mice was reversed by bsyz by regulating the expression of bcl‑2, bax and caspase‑3. |
2015-02-12 |
2023-08-13 |
mouse |
| Xiangyu Kong, Wei Kong, Guangxin Miao, Shumin Zhao, Meng Chen, Xiaoying Zheng, Jiangtao Ba. Pretreatment with scutellaria baicalensis stem-leaf total flavonoid protects against cerebral ischemia/reperfusion injury in hippocampal neurons. Neural regeneration research. vol 9. issue 23. 2015-02-06. PMID:25657723. |
the underlying mechanisms may involve reducing brain water content, increasing microvascular recanalization, inhibiting the apoptosis of hippocampal neurons, and attenuating free radical damage. |
2015-02-06 |
2023-08-13 |
rat |
| Kunio Doi, Koji Uetsuk. Mechanisms of mycotoxin-induced neurotoxicity through oxidative stress-associated pathways. International journal of molecular sciences. vol 12. issue 8. 2015-01-29. PMID:21954354. |
ota causes acute depletion of striatal dopamine and its metabolites, accompanying evidence of neuronal cell apoptosis in the substantia nigra, striatum and hippocampus. |
2015-01-29 |
2023-08-12 |
Not clear |
| Fang Wang, Chan Wang, Yueming Jiang, Xiangfa Deng, Jipei Lu, Shiyan O. Protective role of sodium para-amino salicylic acid against manganese-induced hippocampal neurons damage. Environmental toxicology and pharmacology. vol 37. issue 3. 2015-01-29. PMID:24769799. |
hippocampal neurons were exposed to 50 μm manganese chloride (mncl(2)) for 24 h, following by 50, 500, or 5000 μm pas treatment for 24 h. cell viability, apoptosis rate, mean fluorescence intensity of mitochondrial and dna damage were respectively performed. |
2015-01-29 |
2023-08-13 |
human |
| Hai-Yan Han, Jin-Ping Zhang, Su-Qiong Ji, Qi-Ming Liang, Hui-Cong Kang, Rong-Hua Tang, Sui-Qiang Zhu, Zheng Xu. αν and β1 Integrins mediate Aβ-induced neurotoxicity in hippocampal neurons via the FAK signaling pathway. PloS one. vol 8. issue 6. 2015-01-28. PMID:23755149. |
moreover, tunel immunostaining and flow cytometry indicated that both 17e6 and ab58524 significantly protected hippocampal neurons against apoptosis induced by aβ (p<0.05) compared with the aβ-treated cells. |
2015-01-28 |
2023-08-12 |
Not clear |
| Mingyan Liu, Fujun Chen, Lei Sha, Shuang Wang, Lin Tao, Lutian Yao, Miao He, Zhimin Yao, Hang Liu, Zheng Zhu, Zhenjie Zhang, Zhihong Zheng, Xianzheng Sha, Minjie We. (-)-Epigallocatechin-3-gallate ameliorates learning and memory deficits by adjusting the balance of TrkA/p75NTR signaling in APP/PS1 transgenic mice. Molecular neurobiology. vol 49. issue 3. 2015-01-26. PMID:24356899. |
moreover, after egcg treatment, trka signaling was activated by increasing the phosphorylation of trka following the increased phosphorylation of c-raf, erk1/2, and camp response element-binding protein (creb), simultaneously the p75ntr signaling was significantly inhibited by decreasing the p75icd expression, jnk2 phosphorylation, and cleaved-caspase 3 expression, so that the aβ deposits and neuronal apoptosis in the hippocampus were inhibited. |
2015-01-26 |
2023-08-12 |
mouse |
| Mary E Blue, Mary Ann Wilson, Claude A Beaty, Timothy J George, George J Arnaoutakis, Kara A Haggerty, Melissa Jones, Jeffrey Brawn, Shaliza Manmohan, Mary S Lange, Michael V Johnston, William A Baumgartner, Juan C Troncos. Brain injury in canine models of cardiac surgery. Journal of neuropathology and experimental neurology. vol 73. issue 12. 2015-01-26. PMID:25383634. |
apoptosis developed as early as 2 hours after injury and was most severe in the granule cells of the hippocampal dentate gyrus. |
2015-01-26 |
2023-08-13 |
dog |
| Yujuan Li, Minting Zeng, Weiqiang Chen, Chuiliang Liu, Fei Wang, Xue Han, Zhiyi Zuo, Shuling Pen. Dexmedetomidine reduces isoflurane-induced neuroapoptosis partly by preserving PI3K/Akt pathway in the hippocampus of neonatal rats. PloS one. vol 9. issue 4. 2015-01-15. PMID:24743508. |
terminal deoxyribonucleotide transferase-mediated dutp nick end labeling (tunel) and activated caspase-3 were used to detect neuronal apoptosis in their hippocampus. |
2015-01-15 |
2023-08-13 |
rat |