Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Ling Wei, Shujuan Lv, Quanfang Huang, Jinbin Wei, Shijun Zhang, Renbin Huang, Zhongpeng Lu, Xing Li. Pratensein attenuates Aβ-induced cognitive deficits in rats: enhancement of synaptic plasticity and cholinergic function. Fitoterapia. vol 101. 2015-05-29. PMID:25665942. |
the results showed that pratensein treatment significantly protected against aβ1-42-induced cognitive impairments, as evidenced by the improvement in learning and memory and the attenuation of neuronal degeneration and apoptosis in hippocampus. |
2015-05-29 |
2023-08-13 |
rat |
Changhe Ren, Xuan Yu, Gangming Wu, Changli Liao, Qiao Tang, Jian Zhan, Cehua O. The experiment research of neuroprotection of hypoperfusion postconditioning on cerebral ischemia. The Journal of craniofacial surgery. vol 25. issue 4. 2015-05-28. PMID:25006960. |
this could relate with decreasing expression of tap63 and increasing expression of △np63 in hippocampal region of the first area in the hippocampal circuit to inhibit neuronal apoptosis. |
2015-05-28 |
2023-08-13 |
rat |
Li Sun, Xie-Lai Zhou, Hong-Ping Yi, Su-Jun Jiang, Hong Yua. Lead-induced morphological changes and amyloid precursor protein accumulation in adult rat hippocampus. Biotechnic & histochemistry : official publication of the Biological Stain Commission. vol 89. issue 7. 2015-05-21. PMID:24806610. |
the morphological changes in the hippocampus included mitochondrial degeneration, apoptosis and abnormal synapses in the rats exposed to lead. |
2015-05-21 |
2023-08-13 |
rat |
M I Naseer, I Ullah, M L Narasimhan, H Y Lee, R A Bressan, G H Yoon, D J Yun, M O Ki. Neuroprotective effect of osmotin against ethanol-induced apoptotic neurodegeneration in the developing rat brain. Cell death & disease. vol 5. 2015-05-18. PMID:24675468. |
administration of osmotin to rat pups reduced ethanol-induced apoptosis in cortical and hippocampal neurons. |
2015-05-18 |
2023-08-12 |
rat |
M I Naseer, I Ullah, M L Narasimhan, H Y Lee, R A Bressan, G H Yoon, D J Yun, M O Ki. Neuroprotective effect of osmotin against ethanol-induced apoptotic neurodegeneration in the developing rat brain. Cell death & disease. vol 5. 2015-05-18. PMID:24675468. |
adiponectin can protect hippocampal neurons against ethanol-induced apoptosis. |
2015-05-18 |
2023-08-12 |
rat |
Shu-Qun Hu, Yan-Yan Zong, Guang-Yi Zhan. [Overexpression of PDZ1 domain of PSD-95 protein rescues hippocampal neurons from apoptosis induced by oxygen-glucose deprivation]. Sheng li xue bao : [Acta physiologica Sinica]. vol 60. issue 6. 2015-05-16. PMID:19082428. |
[overexpression of pdz1 domain of psd-95 protein rescues hippocampal neurons from apoptosis induced by oxygen-glucose deprivation]. |
2015-05-16 |
2023-08-12 |
rat |
Shu-Qun Hu, Yan-Yan Zong, Guang-Yi Zhan. [Overexpression of PDZ1 domain of PSD-95 protein rescues hippocampal neurons from apoptosis induced by oxygen-glucose deprivation]. Sheng li xue bao : [Acta physiologica Sinica]. vol 60. issue 6. 2015-05-16. PMID:19082428. |
to detect the effect of pdz1, domain of postsynaptic density 95 (psd-95), on apoptosis of hippocampal neurons induced by oxygen-glucose deprivation (ogd), sprague-dawley rat hippocampal neurons were infected with pdz1-viruses after 21 days of plating. |
2015-05-16 |
2023-08-12 |
rat |
Shu-Qun Hu, Yan-Yan Zong, Guang-Yi Zhan. [Overexpression of PDZ1 domain of PSD-95 protein rescues hippocampal neurons from apoptosis induced by oxygen-glucose deprivation]. Sheng li xue bao : [Acta physiologica Sinica]. vol 60. issue 6. 2015-05-16. PMID:19082428. |
the results showed that: (1) pdz1 overexpression was observed in hippocampal neurons; (2) apoptosis induced by ogd was obviously decreased in neurons overexpressing pdz1 (p<0.05); (3) overexpression of pdz1 prevented the binding of glur6 to psd-95; (4) overexpression of pdz1 inhibited mlk3 and jnk1/2 activation induced by ogd. |
2015-05-16 |
2023-08-12 |
rat |
Shu-Qun Hu, Yan-Yan Zong, Guang-Yi Zhan. [Overexpression of PDZ1 domain of PSD-95 protein rescues hippocampal neurons from apoptosis induced by oxygen-glucose deprivation]. Sheng li xue bao : [Acta physiologica Sinica]. vol 60. issue 6. 2015-05-16. PMID:19082428. |
these results indicate that overexpression of pdz1 may prevent hippocampal neurons from apoptosis induced by ogd. |
2015-05-16 |
2023-08-12 |
rat |
Ming Lei, Lu Luo, Shi-Qi Ma, Yan Zhang, Xi-Hong Wu, Liang L. [Behavioral and neurobiological abnormalities induced by social isolation as a useful animal model of schizophrenia]. Sheng li xue bao : [Acta physiologica Sinica]. vol 65. issue 1. 2015-05-16. PMID:23426521. |
finally, social isolation affects cell apoptosis in different brain areas, such as the medial prefrontal cortex, amygdala, nucleus accumbens, and hippocampus. |
2015-05-16 |
2023-08-12 |
rat |
Ling Xu, Ai-Ling Zhou, Min Zha. [Involvement of Toll-like receptor 4 in apoptosis of hippocampal neurons through Akt/FoxO3a/Bim signaling pathways]. Sheng li xue bao : [Acta physiologica Sinica]. vol 66. issue 3. 2015-05-16. PMID:24964849. |
[involvement of toll-like receptor 4 in apoptosis of hippocampal neurons through akt/foxo3a/bim signaling pathways]. |
2015-05-16 |
2023-08-13 |
rat |
Ling Xu, Ai-Ling Zhou, Min Zha. [Involvement of Toll-like receptor 4 in apoptosis of hippocampal neurons through Akt/FoxO3a/Bim signaling pathways]. Sheng li xue bao : [Acta physiologica Sinica]. vol 66. issue 3. 2015-05-16. PMID:24964849. |
the present study was to investigate whether toll-like receptor 4 (tlr4)-mediated akt/foxo3a/bim signaling pathway participated in lipopolysaccharide (lps)-induced apoptosis in hippocampal neurons. |
2015-05-16 |
2023-08-13 |
rat |
Ling Xu, Ai-Ling Zhou, Min Zha. [Involvement of Toll-like receptor 4 in apoptosis of hippocampal neurons through Akt/FoxO3a/Bim signaling pathways]. Sheng li xue bao : [Acta physiologica Sinica]. vol 66. issue 3. 2015-05-16. PMID:24964849. |
in conclusion, the present study suggests that akt/foxo3a/bim signaling pathways mediated by tlr4 participate in the apoptotic processes of primarily cultured hippocampal neurons treated with lps, and the activation of tlr4 causes neuronal apoptosis. |
2015-05-16 |
2023-08-13 |
rat |
Małgorzata Lehner, Aleksandra Wisłowska-Stanek, Anna Skórzewska, Adam Płaźni. Chronic restraint increases apoptosis in the hippocampus of rats with high responsiveness to fear stimuli. Neuroscience letters. vol 586. 2015-05-14. PMID:25486591. |
chronic restraint increases apoptosis in the hippocampus of rats with high responsiveness to fear stimuli. |
2015-05-14 |
2023-08-13 |
rat |
Małgorzata Lehner, Aleksandra Wisłowska-Stanek, Anna Skórzewska, Adam Płaźni. Chronic restraint increases apoptosis in the hippocampus of rats with high responsiveness to fear stimuli. Neuroscience letters. vol 586. 2015-05-14. PMID:25486591. |
this finding suggests that higher susceptibility to fear stimuli predisposes rats to increased apoptosis in the hippocampus after exposure to chronic stressors. |
2015-05-14 |
2023-08-13 |
rat |
Roman A Kireev, Sara Cuesta, Elena Vara, Jesus A F Tresguerre. Effect of growth hormone and melatonin on the brain: from molecular mechanisms to structural changes. Hormone molecular biology and clinical investigation. vol 7. issue 2. 2015-05-13. PMID:25961272. |
both gh and melatonin were able to reduce inflammation and apoptosis in the hippocampus. |
2015-05-13 |
2023-08-13 |
rat |
Roman A Kireev, Sara Cuesta, Elena Vara, Jesus A F Tresguerre. Effect of growth hormone and melatonin on the brain: from molecular mechanisms to structural changes. Hormone molecular biology and clinical investigation. vol 7. issue 2. 2015-05-13. PMID:25961272. |
in conclusion, neuroprotective effects demonstrated by gh and melatonin in the hippocampus were exerted by decreasing inflammation and apoptosis. |
2015-05-13 |
2023-08-13 |
rat |
Zhaoxia Liao, Dexiong Cao, Xue Han, Chuiliang Liu, Jun Peng, Zhiyi Zuo, Fei Wang, Yujuan L. Both JNK and P38 MAPK pathways participate in the protection by dexmedetomidine against isoflurane-induced neuroapoptosis in the hippocampus of neonatal rats. Brain research bulletin. vol 107. 2015-05-12. PMID:25026397. |
terminal deoxyribonucleotide transferase-mediated dutp nick end labeling (tunel) was used to detect neuronal apoptosis in their hippocampus. |
2015-05-12 |
2023-08-13 |
rat |
S Karimi, M Jahanshahi, M J Golalipou. The effect of MDMA-induced anxiety on neuronal apoptosis in adult male rats' hippocampus. Folia biologica. vol 60. issue 4. 2015-05-12. PMID:25152052. |
the effect of mdma-induced anxiety on neuronal apoptosis in adult male rats' hippocampus. |
2015-05-12 |
2023-08-13 |
rat |
S Karimi, M Jahanshahi, M J Golalipou. The effect of MDMA-induced anxiety on neuronal apoptosis in adult male rats' hippocampus. Folia biologica. vol 60. issue 4. 2015-05-12. PMID:25152052. |
the aim of this study was to investigate the effects of mdma on anxiety and apoptosis of hippocampal neurons. |
2015-05-12 |
2023-08-13 |
rat |