| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhen Zhang, Tao Sun, Jian-Guo Niu, Zhen-Quan He, Yang Liu, Feng Wan. Amentoflavone protects hippocampal neurons: anti-inflammatory, antioxidative, and antiapoptotic effects. Neural regeneration research. vol 10. issue 7. 2015-09-02. PMID:26330838. |
amentoflavone effectively prevented pilocarpine-induced epilepsy in a mouse kindling model, suppressed nuclear factor-κb activation and expression, inhibited excessive discharge of hippocampal neurons resulting in a reduction in epileptic seizures, shortened attack time, and diminished loss and apoptosis of hippocampal neurons. |
2015-09-02 |
2023-08-13 |
mouse |
| Xiao-Lan Qian, Wei Zhang, Ming-Zheng Liu, Yu-Bing Zhou, Jing-Min Zhang, Li Han, You-Mei Peng, Jin-hua Jiang, Qing-Duan Wan. Dexmedetomidine improves early postoperative cognitive dysfunction in aged mice. European journal of pharmacology. vol 746. 2015-08-31. PMID:25460022. |
these results suggest that hippocampal inflammatory response and neuronal apoptosis may contribute to pocd, and selective alpha 2 adrenal receptor excitation play a protective role. |
2015-08-31 |
2023-08-13 |
mouse |
| Hui-Yun Yang, Yang Liu, Jia-Cun Xie, Nan-Nan Liu, Xin Tia. Effects of repetitive transcranial magnetic stimulation on synaptic plasticity and apoptosis in vascular dementia rats. Behavioural brain research. vol 281. 2015-08-31. PMID:25541037. |
this study aims to determine whether low-frequency repetitive transcranial magnetic stimulation (rtms) protects pyramidal cells from apoptosis and promotes hippocampal synaptic plasticity in a vascular dementia (vad) rat model. |
2015-08-31 |
2023-08-13 |
rat |
| Mercedes Garcia-Gil, Andrea Lazzarini, Remo Lazzarini, Emanuela Floridi, Samuela Cataldi, Alessandro Floridi, Elisabetta Alb. Serum deprivation alters lipid profile in HN9.10e embryonic hippocampal cells. Neuroscience letters. vol 589. 2015-08-27. PMID:25556686. |
in hn9.10e embryonic hippocampal cells, serum deprivation induces apoptosis preceded by sphingomyelinase activation and raise of ceramide levels. |
2015-08-27 |
2023-08-13 |
Not clear |
| Min Zhu, Mengru Lu, Qing-Jie Li, Zhuo Zhang, Zheng-Zheng Wu, Jie Li, Lai Qian, Yun Xu, Zhong-Yuan Wan. Hyperbaric oxygen suppresses hypoxic-ischemic brain damage in newborn rats. Journal of child neurology. vol 30. issue 1. 2015-08-25. PMID:24762865. |
fourteen days after hypoxic-ischemic brain damage, cell density and apoptosis rate, number of fas-l+, caspase-8+, and caspase-3+ neuronal cells, levels of nitric oxide, malondialdehyde, and superoxide dismutase in hippocampus were examined. |
2015-08-25 |
2023-08-13 |
rat |
| Xiao Yuan, Xueling Guo, Yan Deng, Die Zhu, Jin Shang, Huiguo Li. Chronic intermittent hypoxia-induced neuronal apoptosis in the hippocampus is attenuated by telmisartan through suppression of iNOS/NO and inhibition of lipid peroxidation and inflammatory responses. Brain research. vol 1596. 2015-08-24. PMID:25463026. |
chronic intermittent hypoxia-induced neuronal apoptosis in the hippocampus is attenuated by telmisartan through suppression of inos/no and inhibition of lipid peroxidation and inflammatory responses. |
2015-08-24 |
2023-08-13 |
rat |
| Xiao Yuan, Xueling Guo, Yan Deng, Die Zhu, Jin Shang, Huiguo Li. Chronic intermittent hypoxia-induced neuronal apoptosis in the hippocampus is attenuated by telmisartan through suppression of iNOS/NO and inhibition of lipid peroxidation and inflammatory responses. Brain research. vol 1596. 2015-08-24. PMID:25463026. |
here, we examined the neuroprotective effects of telmisartan against hippocampal apoptosis induced by chronic intermittent hypoxia (cih), the most characteristic pathophysiological change of osas. |
2015-08-24 |
2023-08-13 |
rat |
| Xiao Yuan, Xueling Guo, Yan Deng, Die Zhu, Jin Shang, Huiguo Li. Chronic intermittent hypoxia-induced neuronal apoptosis in the hippocampus is attenuated by telmisartan through suppression of iNOS/NO and inhibition of lipid peroxidation and inflammatory responses. Brain research. vol 1596. 2015-08-24. PMID:25463026. |
neuronal apoptosis in the hippocampal ca1 region, nos activity, no content, and the presence of inflammatory agents and radical oxygen species in the hippocampus were determined. |
2015-08-24 |
2023-08-13 |
rat |
| Xiao Yuan, Xueling Guo, Yan Deng, Die Zhu, Jin Shang, Huiguo Li. Chronic intermittent hypoxia-induced neuronal apoptosis in the hippocampus is attenuated by telmisartan through suppression of iNOS/NO and inhibition of lipid peroxidation and inflammatory responses. Brain research. vol 1596. 2015-08-24. PMID:25463026. |
in addition, telmisartan significantly ameliorated the hippocampal apoptosis induced by cih. |
2015-08-24 |
2023-08-13 |
rat |
| Xiao Yuan, Xueling Guo, Yan Deng, Die Zhu, Jin Shang, Huiguo Li. Chronic intermittent hypoxia-induced neuronal apoptosis in the hippocampus is attenuated by telmisartan through suppression of iNOS/NO and inhibition of lipid peroxidation and inflammatory responses. Brain research. vol 1596. 2015-08-24. PMID:25463026. |
in conclusion, pre-cih telmisartan administration attenuated cih-induced hippocampal apoptosis partly by regulating nos activity, inhibiting excessive no generation, and reducing lipid peroxidation and inflammatory responses. |
2015-08-24 |
2023-08-13 |
rat |
| Irene Paterniti, Marika Cordaro, Michela Campolo, Rosalba Siracusa, Carolin Cornelius, Michele Navarra, Salvatore Cuzzocrea, Emanuela Esposit. Neuroprotection by association of palmitoylethanolamide with luteolin in experimental Alzheimer's disease models: the control of neuroinflammation. CNS & neurological disorders drug targets. vol 13. issue 9. 2015-08-19. PMID:25106636. |
for the organotypic model of ad, hippocampal slice cultures were prepared from mice at postnatal day 6 and after 21 days of culturing the slices were pre-treated with co-ultrapealut (reference concentrations: 27, 2.7 and 0.27 µm pea) for 2 h and then incubated with aβ₁₋₄₂ (1 µg/ml) for 24 h. pre-treatment with co-ultrapealut significantly reduced inducible nitric oxide synthase and glial fibrillary acidic protein expression, restored neuronal nitric oxide synthase and brainderived neurotrophic factor and reduced the apoptosis. |
2015-08-19 |
2023-08-13 |
mouse |
| Ying Han, Wenxia Yi, Jiong Qin, Yang Zhao, Jing Zhang, Xingzhi Chan. Carbon monoxide offers neuroprotection from hippocampal cell damage induced by recurrent febrile seizures through the PERK-activated ER stress pathway. Neuroscience letters. vol 585. 2015-08-19. PMID:25434873. |
in the present study, using a rat model of recurrent febrile seizures (fss), we found an increase in plasma co, evidence of neuronal damage and apoptosis, an increase in the expression of the endoplasmic reticulum stress (ers) marker glucose-regulated protein 78 (grp78) and c/ebp homologous binding protein (chop), and an increase in phosphorylated protein kinase rna-like endoplasmic reticulum kinase (p-perk)/eukaryotic translation initiation factor 2 alpha (p-eif2α) in the hippocampus after 10 fss. |
2015-08-19 |
2023-08-13 |
rat |
| Ying Han, Wenxia Yi, Jiong Qin, Yang Zhao, Jing Zhang, Xingzhi Chan. Carbon monoxide offers neuroprotection from hippocampal cell damage induced by recurrent febrile seizures through the PERK-activated ER stress pathway. Neuroscience letters. vol 585. 2015-08-19. PMID:25434873. |
administration of hemin (a co donor) in fs rats alleviated the neuronal damage, reduced neuronal apoptosis, upregulated grp78 expression, decreased chop, and increased p-perk and p-eif2α expression in the hippocampus, compared to fs control rats. |
2015-08-19 |
2023-08-13 |
rat |
| Shao-huai Shi, Xu Zhao, Ai-jing Liu, Bing Liu, Huan Li, Bo Wu, Kai-shun Bi, Ying Ji. Protective effect of n-butanol extract from Alpinia oxyphylla on learning and memory impairments. Physiology & behavior. vol 139. 2015-08-19. PMID:25446210. |
besides, nb (180 mg/kg, 360 mg/kg) was able to attenuate the neuronal damage and apoptosis in the frontal cortex and hippocampus in mice. |
2015-08-19 |
2023-08-13 |
mouse |
| Quan Ma, Ming Ying, Xiaojing Sui, Huimin Zhang, Haiyan Huang, Linqing Yang, Xinfeng Huang, Zhixiong Zhuang, Jianjun Liu, Xifei Yan. Chronic copper exposure causes spatial memory impairment, selective loss of hippocampal synaptic proteins, and activation of PKR/eIF2α pathway in mice. Journal of Alzheimer's disease : JAD. vol 43. issue 4. 2015-08-18. PMID:25159668. |
in addition, the expression of the pro-apoptotic target molecule c/ebp homology protein (chop) of atf-4 was upregulated and hippocampal neuronal apoptosis was induced by copper exposure. |
2015-08-18 |
2023-08-13 |
mouse |
| WITHDRAWN: Retraction notice to: "Acute ethanol administration affects memory reactivation: a look at the neuronal density and apoptosis in the rat hippocampus" [Pharmacology, Biochemistry and Behavior 102/2 (2012) 321-328 of retracted article]. Pharmacology, biochemistry, and behavior. vol 125. 2015-07-28. PMID:25389541. |
withdrawn: retraction notice to: "acute ethanol administration affects memory reactivation: a look at the neuronal density and apoptosis in the rat hippocampus" [pharmacology, biochemistry and behavior 102/2 (2012) 321-328 of retracted article]. |
2015-07-28 |
2023-08-13 |
rat |
| Lingling Liu, Keliang Xie, Hongguang Chen, Xiaoqing Dong, Yuan Li, Yang Yu, Guolin Wang, Yonghao Y. Inhalation of hydrogen gas attenuates brain injury in mice with cecal ligation and puncture via inhibiting neuroinflammation, oxidative stress and neuronal apoptosis. Brain research. vol 1589. 2015-07-21. PMID:25251596. |
the histopathologic changes and neuronal apoptosis were observed in hippocampus by nissl staining and tunel assay. |
2015-07-21 |
2023-08-13 |
mouse |
| Lin Sun, Chunni Guo, Tao Wang, Xia Li, Guanjun Li, Yanli Luo, Shifu Xia. LIMK1 is involved in the protective effects of bone morphogenetic protein 6 against amyloid-β-induced neurotoxicity in rat hippocampal neurons. Journal of Alzheimer's disease : JAD. vol 42. issue 2. 2015-07-20. PMID:24903778. |
our data demonstrated that bmp6 prevented apoptosis induced by a high dose of aβ25-35, and inhibited rod formation induced by low dose of aβ25-35 in hippocampal neurons. |
2015-07-20 |
2023-08-13 |
rat |
| Minmin Zhu, Jiawei Chen, Meilin Wen, Zhirong Sun, Xia Sun, Jing Wang, Changhong Mia. Propofol protects against angiotensin II-induced mouse hippocampal HT22 cells apoptosis via inhibition of p66Shc mitochondrial translocation. Neuromolecular medicine. vol 16. issue 4. 2015-07-20. PMID:25151272. |
propofol protects against angiotensin ii-induced mouse hippocampal ht22 cells apoptosis via inhibition of p66shc mitochondrial translocation. |
2015-07-20 |
2023-08-13 |
mouse |
| Minmin Zhu, Jiawei Chen, Meilin Wen, Zhirong Sun, Xia Sun, Jing Wang, Changhong Mia. Propofol protects against angiotensin II-induced mouse hippocampal HT22 cells apoptosis via inhibition of p66Shc mitochondrial translocation. Neuromolecular medicine. vol 16. issue 4. 2015-07-20. PMID:25151272. |
hippocampal neuronal oxidative stress and apoptosis have been reported to be involved in cognitive impairment, and angiotensin ii could induce hippocampal oxidative stress and apoptosis. |
2015-07-20 |
2023-08-13 |
mouse |